PubRank

J Chernoff

Author PubWeight™ 80.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells. Curr Biol 1997 4.91
2 Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J Biol Chem 1995 4.36
3 Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J 1998 3.03
4 Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors. Science 1995 2.87
5 p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J Cell Biol 1999 2.84
6 Identification of a mouse p21Cdc42/Rac activated kinase. J Biol Chem 1995 2.69
7 Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem 2000 2.51
8 The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J Biol Chem 1996 2.45
9 Emerging from the Pak: the p21-activated protein kinase family. Trends Cell Biol 1997 2.44
10 Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. Immunity 1998 2.23
11 Regulation of macropinocytosis by p21-activated kinase-1. Mol Biol Cell 2000 2.16
12 Cloning and characterization of a human protein kinase with homology to Ste20. J Biol Chem 1995 2.08
13 Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J Biol Chem 1998 2.06
14 Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating. EMBO J 1995 2.00
15 Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase. Proc Natl Acad Sci U S A 1994 2.00
16 Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol Cell Biol 1997 1.94
17 The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem 1996 1.91
18 Temporal and spatial distribution of activated Pak1 in fibroblasts. J Cell Biol 2000 1.82
19 Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1. J Biol Chem 2000 1.64
20 Cloning and characterization of a member of the MST subfamily of Ste20-like kinases. Gene 1995 1.63
21 Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas). J Biol Chem 1996 1.58
22 Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor. Biochem J 1997 1.56
23 A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells. Oncogene 2010 1.53
24 Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin. J Biol Chem 1997 1.37
25 Epitope-tag vectors for eukaryotic protein production. Gene 1995 1.30
26 Protein tyrosine phosphatase 1B negatively regulates integrin signaling. Curr Biol 1998 1.27
27 The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis. Mol Cell Biol 1992 1.23
28 Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA. J Biol Chem 1998 1.21
29 Lentivirus Nef specifically activates Pak2. J Virol 2000 1.18
30 Characterization of a phosphotyrosyl protein phosphatase activity associated with a phosphoseryl protein phosphatase of Mr = 95,000 from bovine heart. J Biol Chem 1983 1.18
31 Evidence for a role of mixed lineage kinases in neuronal apoptosis. J Neurosci 2001 1.14
32 Plant GTPases: the Rhos in bloom. Trends Cell Biol 2000 1.14
33 A phosphotyrosyl-protein phosphatase activity associated with acid phosphatase from human prostate gland. Eur J Biochem 1984 1.13
34 A fission-yeast gene encoding a protein with features of protein-tyrosine-phosphatases. Proc Natl Acad Sci U S A 1991 1.12
35 A major phosphotyrosyl-protein phosphatase from bovine heart is associated with a low-molecular-weight acid phosphatase. Arch Biochem Biophys 1985 1.10
36 Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand. Mol Cell Biol 1998 1.08
37 The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity. Oncogene 2006 1.07
38 Characterization of Pak2p, a pleckstrin homology domain-containing, p21-activated protein kinase from fission yeast. J Biol Chem 1998 1.02
39 Down-regulation of insulin signaling by protein-tyrosine phosphatase 1B is mediated by an N-terminal binding region. J Biol Chem 2000 0.96
40 Nerve growth factor stimulates tyrosine phosphorylation and activation of Src homology-containing protein-tyrosine phosphatase 1 in PC12 cells. J Biol Chem 1995 0.92
41 Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42. J Biol Chem 2001 0.92
42 Delivery of protein into cells using polycationic liposomes. Biotechniques 1995 0.87
43 Long-term culture and passage of human fetal liver cells that synthesize albumin. In Vitro Cell Dev Biol 1985 0.85
44 Multiple forms of phosphotyrosyl- and phosphoseryl-protein phosphatase from cardiac muscle: partial purification and characterization of an EDTA-stimulated phosphotyrosyl-protein phosphatase. Arch Biochem Biophys 1983 0.84
45 Close encounters of the LIM-kinase. Nat Cell Biol 1999 0.83
46 Characterization of phosphotyrosyl-protein phosphatase activity associated with calcineurin. Biochem Biophys Res Commun 1984 0.81
47 Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase. Virus Res 2010 0.80
48 Two-hybrid dual bait system to discriminate specificity of protein interactions in small GTPases. Methods Enzymol 2001 0.79
49 The role of p21-activated kinase in the initiation of atherosclerosis. BMC Cardiovasc Disord 2012 0.79
50 Determinants of patient adherence to consultative comprehensive geriatric assessment recommendations. J Gerontol A Biol Sci Med Sci 1997 0.77
51 Polymerase chain reaction cloning of related genes. Methods Enzymol 1995 0.75