Published in Zygote on August 25, 2010
MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival. Cancer Res (2008) 2.33
Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res (2005) 2.19
Randomized phase III trial of gemcitabine-based chemotherapy with in situ RRM1 and ERCC1 protein levels for response prediction in non-small-cell lung cancer. J Clin Oncol (2009) 2.13
ERK activation drives intestinal tumorigenesis in Apc(min/+) mice. Nat Med (2010) 2.09
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies. Nat Biotechnol (2013) 1.71
Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis. J Biol Chem (2008) 1.64
Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes. Biochim Biophys Acta (2002) 1.61
Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes. Proc Natl Acad Sci U S A (2011) 1.57
A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans. J Immunol (2010) 1.55
Randomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol (2013) 1.55
The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis (2002) 1.55
Possible genomic imprinting of three human obesity-related genetic loci. Am J Hum Genet (2005) 1.54
Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury. J Neurosci (2007) 1.54
Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection. J Immunol (2010) 1.49
Common cerebral networks associated with distinct deep brain stimulation targets for cluster headache. Cephalalgia (2013) 1.43
Corticosteroid Therapy Benefits Septic Mice With Adrenal Insufficiency But Harms Septic Mice Without Adrenal Insufficiency. Crit Care Med (2015) 1.39
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol (2009) 1.39
Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev Vaccines (2009) 1.34
Characterization of Chlamydia trachomatis plasmid-encoded open reading frames. J Bacteriol (2013) 1.31
Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Mol Cell Biol (2005) 1.31
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent. Proc Natl Acad Sci U S A (2013) 1.20
Identifying the main mosquito species in China based on DNA barcoding. PLoS One (2012) 1.19
Characterization of Pgp3, a Chlamydia trachomatis plasmid-encoded immunodominant antigen. J Bacteriol (2010) 1.18
Effect of surface roughness on stain resistance of dental resin composites. J Esthet Restor Dent (2005) 1.17
Glutathione-indole-3-acetonitrile is required for camalexin biosynthesis in Arabidopsis thaliana. Plant Cell (2011) 1.15
A novel two-step strategy for in vitro culture of early-stage ovarian follicles in the mouse. Fertil Steril (2009) 1.15
ATG16L1 T300A polymorphism and Crohn's disease susceptibility: evidence from 13,022 cases and 17,532 controls. Hum Genet (2009) 1.11
Never smokers and lung cancer risk: a case-control study of epidemiological factors. Int J Cancer (2006) 1.10
Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner. BMC Microbiol (2008) 1.10
DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA. Carcinogenesis (2012) 1.10
Frequency and distribution in East Asia of 12 mutations identified in the SLC25A13 gene of Japanese patients with citrin deficiency. J Hum Genet (2005) 1.09
Optofluidic planar reactors for photocatalytic water treatment using solar energy. Biomicrofluidics (2010) 1.08
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway. Microbiology (2010) 1.08
Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1. Microbiology (2011) 1.07
Multi-institutional evaluation of deep brain stimulation targeting using probabilistic connectivity-based thalamic segmentation. J Neurosurg (2011) 1.07
Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum. PLoS One (2013) 1.06
Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Cancer Res (2004) 1.06
Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events. Stem Cell Res (2012) 1.05
ED handoffs: observed practices and communication errors. Am J Emerg Med (2010) 1.04
The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol. BMC Microbiol (2011) 1.04
Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Clin Cancer Res (2008) 1.04
ERCC1 and RRM1 in the international adjuvant lung trial by automated quantitative in situ analysis. Am J Pathol (2010) 1.04
The Nell-1 growth factor stimulates bone formation by purified human perivascular cells. Tissue Eng Part A (2011) 1.02
Complexes with mixed primary and secondary cellulose synthases are functional in Arabidopsis plants. Plant Physiol (2012) 1.01
Brn3a regulation of TrkA/NGF receptor expression in developing sensory neurons. Development (2003) 1.01
Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer. Lung Cancer (2004) 1.01
Molecular characterization of four rice genes encoding ethylene-responsive transcriptional factors and their expressions in response to biotic and abiotic stress. J Plant Physiol (2006) 1.01
Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance. Lung Cancer (2005) 1.01
Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling. Nat Immunol (2012) 1.01
Expression and localization of Hsps in the heart and blood vessel of heat-stressed broilers. Cell Stress Chaperones (2008) 1.01
Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma. Cancer Lett (2012) 1.00
Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells. Microb Pathog (2010) 1.00
Prevalence and severity of chronic kidney disease and anemia in the nursing home population. J Am Med Dir Assoc (2009) 0.99
The antimicrobial and osteoinductive properties of silver nanoparticle/poly (DL-lactic-co-glycolic acid)-coated stainless steel. Biomaterials (2012) 0.99
Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Dev Dyn (2013) 0.98
Efficient gene silencing induction in tomato by a viral satellite DNA vector. Virus Res (2007) 0.97
A quantitative approach to scar analysis. Am J Pathol (2011) 0.96
Deficiency of scavenger receptor BI leads to impaired lymphocyte homeostasis and autoimmune disorders in mice. Arterioscler Thromb Vasc Biol (2011) 0.96
Molecular characterization and expression analysis of OsBISERK1, a gene encoding a leucine-rich repeat receptor-like kinase, during disease resistance responses in rice. Mol Biol Rep (2007) 0.96
High density lipoprotein protects against polymicrobe-induced sepsis in mice. J Biol Chem (2013) 0.96
Long-term outcomes of vitrectomy for progressive X-linked retinoschisis. Am J Ophthalmol (2012) 0.95
The endocytosis of cellulose synthase in Arabidopsis is dependent on μ2, a clathrin-mediated endocytosis adaptin. Plant Physiol (2013) 0.95
Cell wall, cytoskeleton, and cell expansion in higher plants. Mol Plant (2014) 0.94
Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection. Infect Immun (2014) 0.94
A Chlamydia trachomatis OmcB C-terminal fragment is released into the host cell cytoplasm and is immunogenic in humans. Infect Immun (2011) 0.94
Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma. J Hematol Oncol (2013) 0.94
Features of potentially predictive biomarkers of chemotherapeutic efficacy in small cell lung cancer. J Thorac Oncol (2010) 0.93
CD14 C-260T gene polymorphism and ischemic heart disease susceptibility: a HuGE review and meta-analysis. Genet Med (2009) 0.92
High-order photonic differentiator employing on-chip cascaded microring resonators. Opt Lett (2013) 0.92
Chlamydia trachomatis secretion of an immunodominant hypothetical protein (CT795) into host cell cytoplasm. J Bacteriol (2011) 0.92
Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone. Cell Res (2004) 0.91
Serum DJ-1 as a diagnostic marker and prognostic factor for pancreatic cancer. J Dig Dis (2011) 0.91
Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro. Acta Pharmacol Sin (2010) 0.91
Genetic susceptibility for lung cancer: interactions with gender and smoking history and impact on early detection policies. Hum Hered (2003) 0.90
Compact, flexible and versatile photonic differentiator using silicon Mach-Zehnder interferometers. Opt Express (2013) 0.90
Early treatment with hepatocyte growth factor improves cardiac function in experimental heart failure induced by myocardial infarction. J Pharmacol Exp Ther (2003) 0.90
Overexpression in transgenic tobacco reveals different roles for the rice homeodomain gene OsBIHD1 in biotic and abiotic stress responses. J Exp Bot (2005) 0.90
Effects of hypoxia on osteogenic differentiation of rat bone marrow mesenchymal stem cells. Mol Cell Biochem (2011) 0.90
Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk. Cancer (2003) 0.90
[A dyslipidemia animal model induced by poloxamer 407 in golden hamsters and pilot study on the mechanism]. Yao Xue Xue Bao (2011) 0.90
Polyhydroxyalkanoate synthases PhaC1 and PhaC2 from Pseudomonas stutzeri 1317 had different substrate specificities. FEMS Microbiol Lett (2004) 0.89
Imprinting detection by extending a regression-based QTL analysis method. Hum Genet (2007) 0.89
Chlamydia trachomatis outer membrane complex protein B (OmcB) is processed by the protease CPAF. J Bacteriol (2012) 0.89
Poly(hydroxybutyrate-co-hydroxyhexanoate) promoted production of extracellular matrix of articular cartilage chondrocytes in vitro. Biomaterials (2003) 0.89
Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells. Cancer Biol Ther (2009) 0.89
Distinct roles of CD28- and CD40 ligand-mediated costimulation in the development of protective immunity and pathology during Chlamydia muridarum urogenital infection in mice. Infect Immun (2009) 0.89
Antiapoptotic signaling pathways in non-small-cell lung cancer: biology and therapeutic strategies. Clin Lung Cancer (2004) 0.89
Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells. Acta Biochim Biophys Sin (Shanghai) (2011) 0.88
Multi-residue method for fast determination of pesticide residues in plants used in traditional chinese medicine by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry. J Chromatogr A (2011) 0.88
Rotation of meiotic spindle is controlled by microfilaments in mouse oocytes. Biol Reprod (2003) 0.88
Alteration of gene expression profile in maize infected with a double-stranded RNA fijivirus associated with symptom development. Mol Plant Pathol (2011) 0.88
Chlamydia trachomatis GlgA is secreted into host cell cytoplasm. PLoS One (2013) 0.88
Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway. Mol Cell Endocrinol (2006) 0.87
Neuregulin-1/ErbB signaling is impaired in the rat model of diabetic cardiomyopathy. Cardiovasc Pathol (2012) 0.87
Modification of Wiener Index and its application. J Chem Inf Comput Sci (2003) 0.87
A nodule-specific plant cysteine proteinase, AsNODF32, is involved in nodule senescence and nitrogen fixation activity of the green manure legume Astragalus sinicus. New Phytol (2008) 0.87
Recent progress in nanotechnology for cancer therapy. Chin J Cancer (2010) 0.87
Photocaged DNAzymes as a general method for sensing metal ions in living cells. Angew Chem Int Ed Engl (2014) 0.87