G Jay

Author PubWeight™ 175.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse. Proc Natl Acad Sci U S A 1979 6.93
2 HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991 5.34
3 Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell 1979 4.30
4 The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice. Science 1987 4.01
5 Identification of the SV40 agnogene product: a DNA binding protein. Nature 1981 3.80
6 p53 transformation-related protein: detection by monoclonal antibody in mouse and human cells. Proc Natl Acad Sci U S A 1981 3.72
7 The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature 1988 3.07
8 Unusual features in the nucleotide sequence of a cDNA clone derived from the common region of avian sarcoma virus messenger RNA. Proc Natl Acad Sci U S A 1980 2.45
9 Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma viruses. Science 1985 2.23
10 Reversal of oncogenesis by the expression of a major histocompatibility complex class I gene. Science 1985 2.22
11 Secretion of a transplantation-related antigen. Cell 1983 2.12
12 A nonpolymorphic class I gene in the murine major histocompatibility complex. Cell 1984 2.12
13 Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice. Science 1989 2.08
14 The released interleukin 2 receptor binds interleukin 2 efficiently. J Immunol 1986 2.08
15 A transgenic mouse model for human neurofibromatosis. Science 1987 2.05
16 The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet 1995 2.03
17 Gene expression: chemical synthesis of E. coli ribosome binding sites and their use in directing the expression of mammalian proteins in bacteria. Nucleic Acids Res 1982 2.01
18 Exocrinopathy resembling Sjögren's syndrome in HTLV-1 tax transgenic mice. Nature 1989 1.98
19 The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells. Mol Cell Biol 1990 1.91
20 Prostate-specific and androgen-dependent expression of a novel homeobox gene. J Biol Chem 1996 1.85
21 Functional inactivation but not structural mutation of p53 causes liver cancer. Nat Genet 1995 1.80
22 Tissue-specific expression of an unusual H-2 (class I)-related gene. Proc Natl Acad Sci U S A 1982 1.76
23 Identification of a transformation-specific protein induced by a Rous sarcoma virus. Cell 1978 1.74
24 A common transformation-related protein in murine sarcomas and leukemias. Cold Spring Harb Symp Quant Biol 1980 1.74
25 Discrete regions of simian virus 40 large T antigen are required for nonspecific and viral origin-specific DNA binding. J Virol 1982 1.71
26 Human error in medicine: promise and pitfalls, part 2. Ann Emerg Med 2000 1.61
27 Role of the major histocompatibility complex class I antigens in tumor growth and metastasis. Annu Rev Immunol 1988 1.60
28 Simian virus 40-specific ribosome-binding proteins induced by a nondefective adenovirus 2-simian virus 40 hybrid. J Virol 1977 1.59
29 Detection of a secreted form of the murine H-2 class I antigen with an antibody against its predicted carboxyl terminus. Proc Natl Acad Sci U S A 1984 1.58
30 Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J Biol Chem 2000 1.57
31 New chimeric splice junction in adenovirus type 2-simian virus 40 hybrid viral mRNA. J Virol 1980 1.53
32 A transcriptional enhancer and an interferon-responsive sequence in major histocompatibility complex class I genes. Mol Cell Biol 1986 1.50
33 Characterization of an immune complex kinase in immunoprecipitates of avian sarcoma virus-transformed fibroblasts. J Virol 1979 1.48
34 Three classes of mouse H-2 messenger RNA distinguished by analysis of cDNA clones. Nature 1982 1.48
35 Regulated expression of a murine class I gene in transgenic mice. Mol Cell Biol 1986 1.44
36 Developmental activation of the H-2K gene is correlated with an increase in DNA methylation. Cell 1983 1.44
37 Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice. Proc Natl Acad Sci U S A 1986 1.43
38 Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain. J Virol 1983 1.42
39 Expression of the complete human T-cell leukemia virus type I pX coding sequence as a functional protein in Escherichia coli. Proc Natl Acad Sci U S A 1986 1.41
40 Modulation of the tumorigenicity of human adenovirus-12-transformed cells by interferon. Cell 1985 1.41
41 Combination chemotherapy with bleomycin, etoposide and cisplatin (BEP) for metastatic testicular teratoma: long-term follow-up. Eur J Cancer 1991 1.39
42 Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene. J Exp Med 1997 1.38
43 The early region of human papovavirus JC induces dysmyelination in transgenic mice. Cell 1986 1.35
44 Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice. J Exp Med 1988 1.34
45 Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis. J Clin Invest 1996 1.33
46 Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene. Virology 1989 1.32
47 Construction of a general vector for efficient expression of mammalian proteins in bacteria: use of a synthetic ribosome binding site. Proc Natl Acad Sci U S A 1981 1.31
48 Molecular mechanism for the capture and excision of the transforming gene of avian sarcoma virus as suggested by analysis of recombinant clones. J Virol 1980 1.31
49 Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization. J Clin Invest 1997 1.31
50 p53 transformation-related protein: detection of an associated phosphotransferase activity. Proc Natl Acad Sci U S A 1981 1.30
51 Subcellular localization of the simian virus 40 agnoprotein. J Virol 1983 1.29
52 Functional insertion of an Alu type 2 (B2 SINE) repetitive sequence in murine class I genes. Science 1984 1.28
53 Expression of major histocompatibility complex class I antigens as a strategy for the potentiation of immune recognition of tumor cells. Proc Natl Acad Sci U S A 1986 1.24
54 Comparison of class I (H-2) gene sequences. Derivation of unique probes for members of this multigene family. J Biol Chem 1983 1.23
55 Altering the boundaries of Hox3.1 expression: evidence for antipodal gene regulation. Cell 1992 1.21
56 Alternative RNA splicing in expression of the H-2K gene. Nature 1984 1.19
57 Specific binding of a chemically synthesized prokaryotic ribosome recognition site. Prospect for molecular cloning and expression of eukaryotic genes. J Biol Chem 1980 1.18
58 Cell-free synthesis of mouse H-2 histocompatibility antigens. Proc Natl Acad Sci U S A 1979 1.16
59 Transgenic mouse model for central nervous system demyelination. Mol Cell Biol 1991 1.15
60 Intensive induction chemotherapy for poor risk non-seminomatous germ cell tumours. Eur J Cancer Clin Oncol 1989 1.13
61 Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence. Proc Natl Acad Sci U S A 1984 1.13
62 trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene. Mol Cell Biol 1989 1.12
63 Immunotherapy of a murine tumor with interleukin 2. Increased sensitivity after MHC class I gene transfection. J Exp Med 1987 1.08
64 Transgenic mouse model for human gastric carcinoma. Proc Natl Acad Sci U S A 1989 1.04
65 Host interference with viral gene expression: mode of action of bacterial factor i. J Mol Biol 1974 1.02
66 Multiple endocrine neoplasia induced by the promiscuous expression of a viral oncogene. Proc Natl Acad Sci U S A 1988 1.02
67 The role of major histocompatibility complex class I antigens in tumorigenesis: future applications in cancer therapy. Biochim Biophys Acta 1989 1.02
68 The molecular basis for the generation of the human soluble interleukin 2 receptor. Cytokine 1990 1.01
69 Mouse Lyt-2 antigen: evidence for two heterodimers with a common subunit. Proc Natl Acad Sci U S A 1982 1.01
70 Biosynthesis, immunological specificity, and intracellular distribution of the simian virus 40-specific protein induced by the nondefective hybrid Ad2+ND1. J Virol 1978 1.00
71 Stress and exercise among the Japanese elderly. Soc Sci Med 1993 1.00
72 Extravasation and transcytosis of liposomes in Kaposi's sarcoma-like dermal lesions of transgenic mice bearing the HIV tat gene. Am J Pathol 1993 1.00
73 Tumor-specific transplantation antigen: use of the Ad2+ND1 hybrid virus to identify the protein responsible for simian virus 40 tumor rejection and its genetic origin. Proc Natl Acad Sci U S A 1978 0.99
74 Activation of retrovirus in transgenic mice: association with development of olfactory neuroblastoma. J Virol 1990 0.97
75 Effectiveness of carboplatin, etoposide, and bleomycin combination chemotherapy in good-prognosis metastatic testicular nonseminomatous germ cell tumors. J Clin Oncol 1991 0.97
76 Rejection of B16 melanoma induced by expression of a transfected major histocompatibility complex class I gene. Mol Cell Biol 1988 0.97
77 Human immunodeficiency virus-associated vasculopathy in transgenic mice. J Virol 1997 0.96
78 Translational repression of a viral messenger RNA by a host protein. J Biol Chem 1975 0.96
79 Liver cancer in transgenic mice carrying the human immunodeficiency virus tat gene. Cancer Res 1991 0.96
80 Suppression of MHC class I RNA in highly oncogenic cells occurs at the level of transcription initiation. J Immunol 1989 0.95
81 Initiation of protein synthesis. Binding of messenger RNA. J Biol Chem 1975 0.94
82 The activity of single-agent carboplatin in advanced seminoma. Eur J Cancer 1992 0.94
83 Sequence of events in initiation of translation: a role for initiator transfer RNA in the recognition of messenger RNA. Proc Natl Acad Sci U S A 1974 0.93
84 Financial strain and psychological well-being among the American and Japanese elderly. Psychol Aging 1991 0.93
85 Orchidectomy alone for stage I seminoma of the testis. Cancer 1990 0.93
86 Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. J Clin Invest 1996 0.92
87 Stable transfer and restricted expression of a cloned class I gene encoding a secreted transplantation-like antigen. Mol Cell Biol 1985 0.91
88 Inhibition of the transformation-specific kinase in ASV-transformed cells by N-alpha-tosyl-L-lysyl chloromethyl ketone. Cell 1979 0.91
89 Comparison of HLA class I gene sequences. Derivation of locus-specific oligonucleotide probes specific for HLA-A, HLA-B, and HLA-C genes. J Biol Chem 1985 0.90
90 JC virus and simian virus 40 enhancers and transforming proteins: role in determining tissue specificity and pathogenicity in transgenic mice. J Virol 1992 0.89
91 Stepwise immortalization and transformation of adult human prostate epithelial cells by a combination of HPV-18 and v-Ki-ras. Proc Natl Acad Sci U S A 1994 0.88
92 Tumors in hepatobiliary tract and pancreatic islet tissues of transgenic mice harboring gastrin simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci U S A 1993 0.88
93 Detailed mapping of the Rfv-1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia. Eur J Immunogenet 1992 0.88
94 Functional expression of a heterologous major histocompatibility complex class I gene in transgenic mice. Mol Cell Biol 1987 0.87
95 Mice transgenic for HTLV-I LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover. Virology 1993 0.87
96 Neoplastic transformation of human keratinocytes by polybrene-induced DNA-mediated transfer of an activated oncogene. Oncogene 1989 0.85
97 A transgenic model of transactivation by the Tax protein of HTLV-I. Virology 1993 0.85
98 A transgenic class I antigen is recognized as self and functions as a restriction element. J Immunol 1987 0.85
99 Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. J Immunol 1987 0.85
100 Repression of the NF1 gene by Tax may expain the development of neurofibromas in human T-lymphotropic virus type 1 transgenic mice. J Virol 1996 0.84
101 The HIV tat gene transforms human keratinocytes. Oncogene 1992 0.84
102 Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene. Mol Cell Biol 1991 0.84
103 Spontaneous deletion mutants resulting from a frameshift insertion in the simian virus 40 agnogene. J Virol 1986 0.83
104 Control of H-2 antigen and beta 2-microglobulin gene expression in mouse trophoblast cell clones. Proc Natl Acad Sci U S A 1983 0.82
105 Expression of heat-shock and glucose-regulated genes: differential effects of glucose starvation and hypertonicity. Biochim Biophys Acta 1988 0.82
106 Hypofractionated radiotherapy for patients with carcinoma of the bladder. Clin Oncol (R Coll Radiol) 1999 0.81
107 Differential susceptibility of human cells to transformation by murine and avian sarcoma viruses. Proc Soc Exp Biol Med 1982 0.81
108 Occurrence of a unique MHC class I gene in distantly related members of the genus Mus. Immunogenetics 1985 0.81
109 The utility of tumour markers in assessing the response to chemotherapy in advanced bladder cancer. Br J Cancer 2000 0.81
110 Molecular dissection of hepatitis C virus expression. Intervirology 2001 0.80
111 Induction of simian virus 40-specific tumour rejection by the Ad2+ND2 hybrid virus. J Gen Virol 1979 0.80
112 Binding of messenger RNA in initiation of prokaryotic translation. Methods Enzymol 1979 0.80
113 Correlation of the induction of transcription of the AKR mouse genome 5-lododeoxyuridine with the activation of an endogenous murine leukemia virus. Cancer Res 1979 0.80
114 Experimental strategies for modification of histocompatibility antigens in tumor cells. Cancer Metastasis Rev 1987 0.80
115 The hiv tat gene is a promoter of epidermal skin tumors. Int J Oncol 1995 0.80
116 Transgenic mouse models of human gastric and hepatic carcinomas. Semin Cancer Biol 1994 0.80
117 Role of major histocompatibility complex class-I molecules in tumor rejection. New insights from studies with synthetic peptides and transgenic mice. Immunol Res 1990 0.79
118 Effects of H-2Kb gene on expression of melanoma-associated antigen and lectin-binding sites on BL6 melanoma cells. Cancer Res 1991 0.79
119 Transgenic dissection of HIV genes involved in lymphoid depletion. J Clin Invest 1997 0.79
120 Expression of a secreted transplantation antigen gene during murine embryogenesis. Mol Cell Biol 1986 0.79
121 Adrenal medullary tumors and iris proliferation in a transgenic mouse model of neurofibromatosis. Am J Pathol 1992 0.79
122 Transgenic approach for the study of pathogenesis induced by human viruses. Mol Biol Med 1989 0.78
123 Resistance of bacterial protein synthesis to double-stranded RNA. Biochem Biophys Res Commun 1974 0.78
124 Neoplastic transformation of a human keratinocyte cell line by the v-fos oncogene. Oncogene 1993 0.78
125 Inhibition of hepatocellular carcinoma development in hepatitis B virus transfected mice by low dietary casein. Hepatology 1997 0.77
126 Synergism between the hbx gene and aflatoxin B-1 in the development of murine liver-cancer. Int J Oncol 1995 0.77
127 Use of transgenic animals to study human retroviruses. Cancer Metastasis Rev 1988 0.76
128 Effect of interferon alpha and cell cycle progression on translation mediated by the hepatitis C virus 5' untranslated region: a study using a transgenic mouse model. J Viral Hepat 2004 0.76
129 Nature and intracellular location of the product of the src gene of avian sarcoma virus. Cold Spring Harb Symp Quant Biol 1980 0.76
130 UV activation of human immunodeficiency virus gene expression in transgenic mice. J Virol 1992 0.75
131 Developmental and tissue-specific regulation of the Q10 class I gene by DNA methylation. Proc Natl Acad Sci U S A 1986 0.75
132 Comparison of synthetic ribosome binding sites for the efficient expression of eukaryotic proteins in Escherichia coli. Gene Amplif Anal 1983 0.75
133 Evolving concepts in molecular pathology. FASEB J 1994 0.75
134 Human error in medicine: promise and pitfalls, part 1. Ann Emerg Med 2000 0.75
135 Differential effects on T cell and NK cell development by tissue-specific expression of H-2D(d) transgene. Eur J Immunol 2000 0.75
136 Accelerated chemotherapy in the treatment of urothelial cancer. Clin Oncol (R Coll Radiol) 2001 0.75
137 Cell surface antigens of chemically induced sarcomas of inbred mice. Transplant Proc 1980 0.75
138 The pathogenic role of human immunodeficiency virus accessory genes in transgenic mice. Curr Top Microbiol Immunol 1995 0.75
139 Clinical genetics, IV. Alzheimer's disease: from gene to pathology. Am J Psychiatry 1997 0.75
140 Increased sensitivity to MHC-nonrestricted lysis of BL6 melanoma cells by transfection with class I H-2Kb gene. J Immunol 1990 0.75
141 Regulating gene expression in transgenic animals. Curr Opin Biotechnol 1992 0.75
142 Characterization of the Epstein-Barr virus isolated from a cell line derived from a patient with American Burkitt's lymphoma. Cancer Res 1981 0.75
143 Upper-extremity deep-vein thrombosis: thrombolytic therapy with anistrepalase. Ann Emerg Med 1993 0.75
144 MHC class I gene expression by tumors: immunotherapeutic implications. Curr Top Microbiol Immunol 1988 0.75
145 Human epithelial cell carcinogenesis: combined action of DNA and RNA tumor viruses produces malignant transformation of primary human epidermal keratinocytes. Carcinog Compr Surv 1985 0.75