Published in Ultrasound Med Biol on September 01, 2010
Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo. IEEE Trans Biomed Eng (2009) 1.97
In vivo transcranial cavitation threshold detection during ultrasound-induced blood-brain barrier opening in mice. Phys Med Biol (2010) 1.94
Noninvasive and localized neuronal delivery using short ultrasonic pulses and microbubbles. Proc Natl Acad Sci U S A (2011) 1.46
Noninvasive and localized blood-brain barrier disruption using focused ultrasound can be achieved at short pulse lengths and low pulse repetition frequencies. J Cereb Blood Flow Metab (2010) 1.42
A quantitative pressure and microbubble-size dependence study of focused ultrasound-induced blood-brain barrier opening reversibility in vivo using MRI. Magn Reson Med (2011) 1.37
Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system. Adv Drug Deliv Rev (2014) 1.34
Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI. Magn Reson Med (2011) 1.33
The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice. J Acoust Soc Am (2011) 1.31
Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo. PLoS One (2011) 1.20
Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. J Control Release (2012) 1.18
Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles. Phys Med Biol (2012) 1.13
Optimization of the ultrasound-induced blood-brain barrier opening. Theranostics (2012) 1.08
Microbubble type and distribution dependence of focused ultrasound-induced blood-brain barrier opening. Ultrasound Med Biol (2013) 1.01
The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure. J Cereb Blood Flow Metab (2014) 0.99
Ultrasound-induced blood-brain barrier opening. Curr Pharm Biotechnol (2012) 0.90
Ultrasound treatment of neurological diseases - current and emerging applications. Nat Rev Neurol (2016) 0.88
Blood-Brain Barrier Opening in Behaving Non-Human Primates via Focused Ultrasound with Systemically Administered Microbubbles. Sci Rep (2015) 0.85
Submicron-bubble-enhanced focused ultrasound for blood-brain barrier disruption and improved CNS drug delivery. PLoS One (2014) 0.85
Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide. Expert Opin Drug Deliv (2013) 0.85
A new brain drug delivery strategy: focused ultrasound-enhanced intranasal drug delivery. PLoS One (2014) 0.84
Effects of the microbubble shell physicochemical properties on ultrasound-mediated drug delivery to the brain. J Control Release (2015) 0.84
FEASIBILITY STUDY OF A CLINICAL BLOOD-BRAIN BARRIER OPENING ULTRASOUND SYSTEM. Nano Life (2010) 0.84
Therapeutic strategies to improve drug delivery across the blood-brain barrier. Neurosurg Focus (2015) 0.83
Targeted and reversible blood-retinal barrier disruption via focused ultrasound and microbubbles. PLoS One (2012) 0.80
Breast tumor response to ultrasound mediated excitation of microbubbles and radiation therapy in vivo. Oncoscience (2016) 0.80
Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound. Neuropharmacology (2016) 0.79
Adenosine receptor agonist NECA increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation. Sci Rep (2016) 0.79
Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound. Ultrasound Med Biol (2015) 0.77
Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability. PLoS One (2016) 0.76
Longitudinal Motor and Behavioral Assessment of Blood-Brain Barrier Opening with Transcranial Focused Ultrasound. Ultrasound Med Biol (2016) 0.76
Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer. Ther Deliv (2015) 0.76
Gene therapy for ocular diseases meditated by ultrasound and microbubbles (Review). Mol Med Rep (2015) 0.75
Unilateral Opening of Rat Blood-Brain Barrier Assisted by Diagnostic Ultrasound Targeted Microbubbles Destruction. Biomed Res Int (2016) 0.75
Nerve growth factor delivery by ultrasound-mediated nanobubble destruction as a treatment for acute spinal cord injury in rats. Int J Nanomedicine (2017) 0.75
Quantification of transient increase of the blood-brain barrier permeability to macromolecules by optimized focused ultrasound combined with microbubbles. Int J Nanomedicine (2014) 0.75
Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice. PLoS One (2016) 0.75
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Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci U S A (2006) 3.70
Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys Med Biol (2006) 3.27
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer (2007) 3.21
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Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. Ultrasound Med Biol (2007) 2.89
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol (2004) 2.76
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg (2006) 2.58
MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol (2005) 2.57
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol (2008) 2.47
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun (2005) 2.28
Drug and gene delivery to the brain: the vascular route. Neuron (2002) 2.17
Ultrasound-mediated cavitation thresholds of liquid perfluorocarbon droplets in vitro. Ultrasound Med Biol (2003) 2.07
Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol (2008) 2.03
Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo. IEEE Trans Biomed Eng (2009) 1.97
Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models. PLoS One (2008) 1.95
Molecules of various pharmacologically-relevant sizes can cross the ultrasound-induced blood-brain barrier opening in vivo. Ultrasound Med Biol (2010) 1.86
Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound. Phys Med Biol (2007) 1.81
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Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption. Ultrasound Med Biol (2007) 1.64
Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med Biol (2007) 1.63
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High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo. Ultrasound Med Biol (2002) 1.49
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Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrason Imaging (2008) 1.41
Ultrasonically produced changes in the blood-brain barrier. AMA Arch Neurol Psychiatry (1956) 1.25
Identifying the inertial cavitation threshold and skull effects in a vessel phantom using focused ultrasound and microbubbles. Ultrasound Med Biol (2010) 1.18
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Apoptosis and programmed cell death: a role in cerebral ischemia. Biomed Pharmacother (1998) 0.78
Optimal Defaults and Active Decisions. Q J Econ (2009) 6.42
Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. Ultrasound Med Biol (2007) 2.89
Pulse wave imaging for noninvasive and quantitative measurement of arterial stiffness in vivo. Am J Hypertens (2010) 2.37
Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo. IEEE Trans Biomed Eng (2009) 1.97
In vivo transcranial cavitation threshold detection during ultrasound-induced blood-brain barrier opening in mice. Phys Med Biol (2010) 1.94
Molecules of various pharmacologically-relevant sizes can cross the ultrasound-induced blood-brain barrier opening in vivo. Ultrasound Med Biol (2010) 1.86
Mapping of cardiac electrical activation with electromechanical wave imaging: an in silico-in vivo reciprocity study. Heart Rhythm (2010) 1.86
A clinical feasibility study of atrial and ventricular electromechanical wave imaging. Heart Rhythm (2013) 1.81
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ECG-gated, mechanical and electromechanical wave imaging of cardiovascular tissues in vivo. Ultrasound Med Biol (2007) 1.54
A composite high-frame-rate system for clinical cardiovascular imaging. IEEE Trans Ultrason Ferroelectr Freq Control (2008) 1.51
Noninvasive and localized neuronal delivery using short ultrasonic pulses and microbubbles. Proc Natl Acad Sci U S A (2011) 1.46
Electromechanical wave imaging of normal and ischemic hearts in vivo. IEEE Trans Med Imaging (2009) 1.43
Pulse wave imaging of normal and aneurysmal abdominal aortas in vivo. IEEE Trans Med Imaging (2008) 1.43
Tissue displacements during acupuncture using ultrasound elastography techniques. Ultrasound Med Biol (2004) 1.42
Noninvasive and localized blood-brain barrier disruption using focused ultrasound can be achieved at short pulse lengths and low pulse repetition frequencies. J Cereb Blood Flow Metab (2010) 1.42
Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrason Imaging (2008) 1.41
High-frame rate, full-view myocardial elastography with automated contour tracking in murine left ventricles in vivo. IEEE Trans Ultrason Ferroelectr Freq Control (2008) 1.40
Quantitative viscoelastic parameters measured by harmonic motion imaging. Phys Med Biol (2009) 1.38
A quantitative pressure and microbubble-size dependence study of focused ultrasound-induced blood-brain barrier opening reversibility in vivo using MRI. Magn Reson Med (2011) 1.37
Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI. Magn Reson Med (2011) 1.33
The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice. J Acoust Soc Am (2011) 1.31
Electromechanical wave imaging for arrhythmias. Phys Med Biol (2011) 1.31
Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates. Appl Phys Lett (2011) 1.30
A novel noninvasive technique for pulse-wave imaging and characterization of clinically-significant vascular mechanical properties in vivo. Ultrason Imaging (2007) 1.27
Theoretical quality assessment of myocardial elastography with in vivo validation. IEEE Trans Ultrason Ferroelectr Freq Control (2007) 1.27
Imaging the electromechanical activity of the heart in vivo. Proc Natl Acad Sci U S A (2011) 1.25
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Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo. PLoS One (2011) 1.20
Numerical study of a simple transcranial focused ultrasound system applied to blood-brain barrier opening. IEEE Trans Ultrason Ferroelectr Freq Control (2010) 1.20
Identifying the inertial cavitation threshold and skull effects in a vessel phantom using focused ultrasound and microbubbles. Ultrasound Med Biol (2010) 1.18
Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles. Phys Med Biol (2012) 1.13
Using implementation intentions prompts to enhance influenza vaccination rates. Proc Natl Acad Sci U S A (2011) 1.08
Myocardial elastography at both high temporal and spatial resolution for the detection of infarcts. Ultrasound Med Biol (2007) 1.07
Single-element focused ultrasound transducer method for harmonic motion imaging. Ultrason Imaging (2006) 1.07
Pulse wave imaging of the human carotid artery: an in vivo feasibility study. IEEE Trans Ultrason Ferroelectr Freq Control (2012) 1.07
Reduced thoracolumbar fascia shear strain in human chronic low back pain. BMC Musculoskelet Disord (2011) 1.07
In vivo feasibility of real-time monitoring of focused ultrasound surgery (FUS) using harmonic motion imaging (HMI). IEEE Trans Biomed Eng (2009) 1.05
Microbubble type and distribution dependence of focused ultrasound-induced blood-brain barrier opening. Ultrasound Med Biol (2013) 1.01
Elastographic imaging of strain distribution in the anterior cruciate ligament and at the ligament-bone insertions. J Orthop Res (2006) 1.01
Effects of various parameters on lateral displacement estimation in ultrasound elastography. Ultrasound Med Biol (2009) 1.00
Single-heartbeat electromechanical wave imaging with optimal strain estimation using temporally unequispaced acquisition sequences. Phys Med Biol (2012) 1.00
Transcranial cavitation detection in primates during blood-brain barrier opening--a performance assessment study. IEEE Trans Ultrason Ferroelectr Freq Control (2014) 0.99
The effect of controlled expression of VEGF by transduced myoblasts in a cardiac patch on vascularization in a mouse model of myocardial infarction. Biomaterials (2012) 0.98
Preliminary validation of angle-independent myocardial elastography using MR tagging in a clinical setting. Ultrasound Med Biol (2008) 0.97
Dependence of the reversibility of focused- ultrasound-induced blood-brain barrier opening on pressure and pulse length in vivo. IEEE Trans Ultrason Ferroelectr Freq Control (2013) 0.96
In vivo study of myocardial elastography under graded ischemia conditions. Phys Med Biol (2011) 0.96
Pulse wave imaging in normal, hypertensive and aneurysmal human aortas in vivo: a feasibility study. Phys Med Biol (2013) 0.95
Dynamic morphometric characterization of local connective tissue network structure in humans using ultrasound. BMC Syst Biol (2007) 0.94
Challenges in atherosclerotic plaque characterization with intravascular ultrasound (IVUS): from data collection to classification. IEEE Trans Inf Technol Biomed (2008) 0.94
Planning prompts as a means of increasing preventive screening rates. Prev Med (2012) 0.93
Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets. J Control Release (2013) 0.92
Imaging of wall motion coupled with blood flow velocity in the heart and vessels in vivo: a feasibility study. Ultrasound Med Biol (2011) 0.92
Radiofrequency ablation in the musculoskeletal system. Semin Roentgenol (2004) 0.91
In vivo characterization of the aortic wall stress-strain relationship. Ultrasonics (2010) 0.91
Ultrasound-induced blood-brain barrier opening. Curr Pharm Biotechnol (2012) 0.90
Theranostic Gd(III)-lipid microbubbles for MRI-guided focused ultrasound surgery. Biomaterials (2011) 0.90
Simulation study of amplitude-modulated (AM) harmonic motion imaging (HMI) for stiffness contrast quantification with experimental validation. Ultrason Imaging (2010) 0.90
Pulse-wave propagation in straight-geometry vessels for stiffness estimation: theory, simulations, phantoms and in vitro findings. J Biomech Eng (2012) 0.90
Performance assessment of HIFU lesion detection by harmonic motion imaging for focused ultrasound (HMIFU): a 3-D finite-element-based framework with experimental validation. Ultrasound Med Biol (2011) 0.89
Sparse matrix beamforming and image reconstruction for 2-D HIFU monitoring using harmonic motion imaging for focused ultrasound (HMIFU) with in vitro validation. IEEE Trans Med Imaging (2014) 0.89
Multi-parametric monitoring and assessment of high-intensity focused ultrasound (HIFU) boiling by harmonic motion imaging for focused ultrasound (HMIFU): an ex vivo feasibility study. Phys Med Biol (2014) 0.88
Mapping the longitudinal wall stiffness heterogeneities within intact canine aortas using Pulse Wave Imaging (PWI) ex vivo. J Biomech (2013) 0.88
Detection of Aortic Wall Inclusion Using Regional Pulse Wave Propagation and Velocity In Silico. Artery Res (2012) 0.88
Serum iron, ferritin, transferrin, total iron binding capacity, hs-CRP, LDL cholesterol and magnesium in children; new reference intervals using the Dade Dimension Clinical Chemistry System. Clin Chim Acta (2004) 0.87
Behavioral economics perspectives on public sector pension plans. J Pension Econ Financ (2011) 0.87
In-vivo Pulse Wave Imaging for arterial stiffness measurement under normal and pathological conditions. Conf Proc IEEE Eng Med Biol Soc (2011) 0.87
Fundamental performance assessment of 2-D myocardial elastography in a phased-array configuration. IEEE Trans Ultrason Ferroelectr Freq Control (2009) 0.84
Acoustic cavitation-based monitoring of the reversibility and permeability of ultrasound-induced blood-brain barrier opening. Phys Med Biol (2015) 0.84
Performance assessment and optimization of Pulse Wave Imaging (PWI) in ex vivo canine aortas and in vivo normal human arteries. Conf Proc IEEE Eng Med Biol Soc (2012) 0.82
Testimonials do not convert patients from brand to generic medication. Am J Manag Care (2013) 0.82
An experimental study on the stiffness of size-isolated microbubbles using atomic force microscopy. IEEE Trans Ultrason Ferroelectr Freq Control (2013) 0.82
Angle-independent and multi-dimensional myocardial elastography--from theory to clinical validation. Ultrasonics (2008) 0.82
Estimation of material elastic moduli in elastography: a local method, and an investigation of Poisson's ratio sensitivity. J Biomech (2004) 0.81
Electromechanical wave imaging of biologically and electrically paced canine hearts in vivo. Ultrasound Med Biol (2013) 0.80
High-resolution ultrasound elastography of articular cartilage in vitro. Conf Proc IEEE Eng Med Biol Soc (2006) 0.80
High-intensity focused ultrasound monitoring using harmonic motion imaging for focused ultrasound (HMIFU) under boiling or slow denaturation conditions. IEEE Trans Ultrason Ferroelectr Freq Control (2015) 0.79
Harmonic motion imaging for abdominal tumor detection and high-intensity focused ultrasound ablation monitoring: an in vivo feasibility study in a transgenic mouse model of pancreatic cancer. IEEE Trans Ultrason Ferroelectr Freq Control (2015) 0.79
Detection of murine infarcts using myocardial elastography at both high temporal and spatial resolution. Conf Proc IEEE Eng Med Biol Soc (2006) 0.79
A mechanical model to compute elastic modulus of tissues for harmonic motion imaging. J Biomech (2008) 0.79
Piecewise Pulse Wave Imaging (pPWI) for Detection and Monitoring of Focal Vascular Disease in Murine Aortas and Carotids In Vivo. IEEE Trans Med Imaging (2015) 0.79
Intensity of signal contacting meniscal surface in recurrent tears on MR arthrography compared with that of contrast material. AJR Am J Roentgenol (2006) 0.79
Non-contact, ultrasound-based indentation method for measuring elastic properties of biological tissues using harmonic motion imaging (HMI). Phys Med Biol (2015) 0.78
Selective nerve root blocks. Semin Roentgenol (2004) 0.78
3D Quasi-Static Ultrasound Elastography With Plane Wave In Vivo. IEEE Trans Med Imaging (2016) 0.78
3D myocardial elastography in vivo. IEEE Trans Med Imaging (2016) 0.78
An inverse approach to determining spatially varying arterial compliance using ultrasound imaging. Phys Med Biol (2016) 0.78
Exploiting flow to control the in vitro spatiotemporal distribution of microbubble-seeded acoustic cavitation activity in ultrasound therapy. Phys Med Biol (2014) 0.77
An all-ultrasound-based system for real-time monitoring and sonication of temperature change and ablation. Conf Proc IEEE Eng Med Biol Soc (2006) 0.77
Atrial electromechanical cycle length mapping in paced canine hearts in vivo. IEEE Trans Ultrason Ferroelectr Freq Control (2015) 0.77