Published in Biochim Biophys Acta on September 08, 2010
Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression. Aging (Albany NY) (2011) 1.74
A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels. Cell Rep (2014) 1.48
Cancer as a metabolic disease: implications for novel therapeutics. Carcinogenesis (2013) 1.38
SOD1 integrates signals from oxygen and glucose to repress respiration. Cell (2013) 1.28
A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. J Cell Biol (2012) 1.24
Reversing the Warburg effect as a treatment for glioblastoma. J Biol Chem (2013) 1.02
Simultaneous steady-state and dynamic 13C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells. J Biol Chem (2014) 1.01
Coordinated metabolic transitions during Drosophila embryogenesis and the onset of aerobic glycolysis. G3 (Bethesda) (2014) 0.98
Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes. EMBO J (2015) 0.98
Natural compounds as regulators of the cancer cell metabolism. Int J Cell Biol (2013) 0.91
The role of mitochondria in yeast programmed cell death. Front Oncol (2012) 0.90
Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells. Front Oncol (2013) 0.90
Golgi apparatus dis- and reorganizations studied with the aid of 2-deoxy-D-glucose and visualized by 3D-electron tomography. Histochem Cell Biol (2016) 0.89
Energy and redox homeostasis in tumor cells. Int J Cell Biol (2012) 0.89
Warburg and Crabtree effects in premalignant Barrett's esophagus cell lines with active mitochondria. PLoS One (2013) 0.88
Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. J Cell Physiol (2013) 0.86
Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation. Stem Cells (2015) 0.85
Yeast as a tool to study signaling pathways in mitochondrial stress response and cytoprotection. ScientificWorldJournal (2012) 0.85
Curcumin inhibits lung cancer invasion and metastasis by attenuating GLUT1/MT1-MMP/MMP2 pathway. Int J Clin Exp Med (2015) 0.85
Effects of Neospora caninum infection on brain microvascular endothelial cells bioenergetics. Parasit Vectors (2013) 0.85
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer. Nutr Metab (Lond) (2017) 0.85
Forward chemical genetics in yeast for discovery of chemical probes targeting metabolism. Molecules (2012) 0.84
Metabolic shifts: a fitness perspective for microbial cell factories. Biotechnol Lett (2012) 0.83
Benchmarking of commercially available CHO cell culture media for antibody production. Appl Microbiol Biotechnol (2015) 0.83
An evolutionary perspective on the Crabtree effect. Front Mol Biosci (2014) 0.83
In scarcity and abundance: metabolic signals regulating cell growth. Physiology (Bethesda) (2013) 0.83
Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells. J Biol Chem (2016) 0.82
L-carnosine affects the growth of Saccharomyces cerevisiae in a metabolism-dependent manner. PLoS One (2012) 0.82
O-linked β-N-acetylglucosamine transferase directs cell proliferation in idiopathic pulmonary arterial hypertension. Circulation (2015) 0.81
Functional and regulatory profiling of energy metabolism in fission yeast. Genome Biol (2016) 0.81
PAT-seq: a method to study the integration of 3'-UTR dynamics with gene expression in the eukaryotic transcriptome. RNA (2015) 0.81
Efavirenz induces neuronal autophagy and mitochondrial alterations. J Pharmacol Exp Ther (2014) 0.81
The Warburg effect and drug resistance. Br J Pharmacol (2016) 0.81
The Natural Product Resveratrol Inhibits Yeast Cell Separation by Extensively Modulating the Transcriptional Landscape and Reprogramming the Intracellular Metabolome. PLoS One (2016) 0.81
Homeostasis and the glycogen shunt explains aerobic ethanol production in yeast. Proc Natl Acad Sci U S A (2015) 0.80
Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.80
Determinants of brain cell metabolic phenotypes and energy substrate utilization unraveled with a modeling approach. PLoS Comput Biol (2012) 0.80
L-methionase: a therapeutic enzyme to treat malignancies. Biomed Res Int (2014) 0.79
Mitochondrial respiratory function induces endogenous hypoxia. PLoS One (2014) 0.79
Evolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity). Cancers (Basel) (2011) 0.79
Role of p90(RSK) in regulating the Crabtree effect: implications for cancer. Biochem Soc Trans (2013) 0.79
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons. Nucleic Acids Res (2015) 0.78
Constrained Allocation Flux Balance Analysis. PLoS Comput Biol (2016) 0.78
Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. CNS Neurol Disord Drug Targets (2013) 0.76
Reduced Histone Expression or a Defect in Chromatin Assembly Induces Respiration. Mol Cell Biol (2016) 0.76
Computational strategies for a system-level understanding of metabolism. Metabolites (2014) 0.76
Measuring oxygen levels in Caco-2 cultures. Hypoxia (Auckl) (2015) 0.76
A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis. Oncotarget (2016) 0.76
Glycolysis for Microbiome Generation. Microbiol Spectr (2015) 0.76
Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer. Cells (2012) 0.76
In vivo nonlinear spectral imaging as a tool to monitor early spectroscopic and metabolic changes in a murine cutaneous squamous cell carcinoma model. Biomed Opt Express (2014) 0.75
Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress. Microb Cell (2017) 0.75
Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites. PLoS One (2017) 0.75
Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J Immunol (2017) 0.75
Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. J Biol Chem (2017) 0.75
Low glucose stress decreases cellular NADH and mitochondrial ATP in colonic epithelial cancer cells: Influence of mitochondrial substrates. Chem Biol Interact (2017) 0.75
Does aberrant membrane transport contribute to poor outcome in adult acute myeloid leukemia? Front Pharmacol (2015) 0.75
An In Vitro Study of the Neurotoxic Effects of N-Benzylpiperazine: A Designer Drug of Abuse. Neurotox Res (2016) 0.75
D-Lactate production as a function of glucose metabolism in Saccharomyces cerevisiae. Yeast (2013) 0.75
Targeting Glycosphingolipid Metabolism to Treat Kidney Disease. Nephron (2016) 0.75
Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest (2017) 0.75
Functional Characterization of Three Concomitant MtDNA LHON Mutations Shows No Synergistic Effect on Mitochondrial Activity. PLoS One (2016) 0.75
Retracted Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect. Am J Cancer Res (2015) 0.75
Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells. Toxicol Sci (2016) 0.75
Impacts of chemical gradients on microbial community structure. ISME J (2017) 0.75
Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation. Sci Rep (2016) 0.75
Restoration of Mitochondrial Gene Expression Using a Cloned Human Gene in Chinese Hamster Lung Cell Mutant. Adv Tech Biol Med (2015) 0.75
Targeted proteome analysis of single-gene deletion strains of Saccharomyces cerevisiae lacking enzymes in the central carbon metabolism. PLoS One (2017) 0.75
A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC). Elife (2017) 0.75
Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes. Biochem J (2017) 0.75
Bridge-Induced Translocation between NUP145 and TOP2 Yeast Genes Models the Genetic Fusion between the Human Orthologs Associated With Acute Myeloid Leukemia. Front Oncol (2017) 0.75
The PWWP domain of the human oncogene WHSC1L1/NSD3 induces a metabolic shift toward fermentation. Oncotarget (2016) 0.75
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science (2003) 4.71
Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling. Antioxid Redox Signal (2010) 1.47
Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect. J Biol Chem (2004) 1.43
Control of mitochondrial volume by mitochondrial metabolic water. Mitochondrion (2011) 1.40
Activation of Ras cascade increases the mitochondrial enzyme content of respiratory competent yeast. Biochem Biophys Res Commun (2002) 1.10
Regional differences in oxidative capacity of rat white adipose tissue are linked to the mitochondrial content of mature adipocytes. Mol Cell Biochem (2004) 1.06
Mitochondrial oxidative phosphorylation is regulated by fructose 1,6-bisphosphate. A possible role in Crabtree effect induction? J Biol Chem (2008) 1.05
Mechanisms of mitochondrial response to variations in energy demand in eukaryotic cells. Am J Physiol Cell Physiol (2006) 1.04
The yeast cAMP protein kinase Tpk3p is involved in the regulation of mitochondrial enzymatic content during growth. Biochim Biophys Acta (2005) 0.97
Site specific alterations of adipose tissue mitochondria in 3'-azido-3'-deoxythymidine (AZT)-treated rats: an early stage in lipodystrophy? Biochem Pharmacol (2005) 0.96
Importance of mitochondrial dynamin-related protein 1 in hypothalamic glucose sensitivity in rats. Antioxid Redox Signal (2012) 0.95
Non-respiratory oxygen consumption pathways in anaerobically-grown Saccharomyces cerevisiae: evidence and partial characterization. Yeast (2002) 0.94
Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species. FEBS Lett (2003) 0.93
Reactive oxygen species-mediated control of mitochondrial biogenesis. Int J Cell Biol (2012) 0.90
Reactive oxygen species-mediated regulation of mitochondrial biogenesis in the yeast Saccharomyces cerevisiae. J Biol Chem (2009) 0.89
A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity. Dis Model Mech (2012) 0.89
In yeast, Ca2+ and octylguanidine interact with porin (VDAC) preventing the mitochondrial permeability transition. Biochim Biophys Acta (2007) 0.89
Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. J Biol Chem (2005) 0.88
cAMP-induced modulation of the growth yield of Saccharomyces cerevisiae during respiratory and respiro-fermentative metabolism. Biochim Biophys Acta (2002) 0.87
Nitric oxide increases oxidative phosphorylation efficiency. J Bioenerg Biomembr (2007) 0.87
Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet. Am J Physiol Endocrinol Metab (2007) 0.87
Kinetic regulation of the mitochondrial glycerol-3-phosphate dehydrogenase by the external NADH dehydrogenase in Saccharomyces cerevisiae. J Biol Chem (2002) 0.86
Growth yield homeostasis in respiring yeast is due to a strict mitochondrial content adjustment. J Biol Chem (2006) 0.85
The trehalose pathway regulates mitochondrial respiratory chain content through hexokinase 2 and cAMP in Saccharomyces cerevisiae. J Biol Chem (2009) 0.85
Thyroid status is a key regulator of both flux and efficiency of oxidative phosphorylation in rat hepatocytes. J Bioenerg Biomembr (2002) 0.84
Effects of decreasing mitochondrial volume on the regulation of the permeability transition pore. J Bioenerg Biomembr (2005) 0.84
Isolation of two cell populations from yeast during high-level alcoholic fermentation that resemble quiescent and nonquiescent cells from the stationary phase on glucose. FEMS Yeast Res (2009) 0.84
Method for functional study of mitochondria in rat hypothalamus. J Neurosci Methods (2008) 0.83
Active proton leak in mitochondria: a new way to regulate substrate oxidation. Biochim Biophys Acta (2009) 0.83
Regulation of mitochondrial biogenesis in eukaryotic cells. Toxicol Mech Methods (2004) 0.81
Electron competition process in respiratory chain: regulatory mechanisms and physiological functions. Biochim Biophys Acta (2010) 0.81
cAMP-induced mitochondrial compartment biogenesis: role of glutathione redox state. J Biol Chem (2012) 0.81
Optical microwell array for large scale studies of single mitochondria metabolic responses. Anal Bioanal Chem (2013) 0.81
Dietary polyphenols preconditioning protects 3T3-L1 preadipocytes from mitochondrial alterations induced by oxidative stress. Int J Biochem Cell Biol (2012) 0.80
Competition of electrons to enter the respiratory chain: a new regulatory mechanism of oxidative metabolism in Saccharomyces cerevisiae. J Biol Chem (2004) 0.80
Acute mitochondrial actions of glitazones on the liver: a crucial parameter for their antidiabetic properties. Cell Physiol Biochem (2011) 0.80
The mitochondrial genome impacts respiration but not fermentation in interspecific Saccharomyces hybrids. PLoS One (2013) 0.79
Electrochemical monitoring of the early events of hydrogen peroxide production by mitochondria. Angew Chem Int Ed Engl (2014) 0.78
Mitochondrial energetic metabolism-some general principles. IUBMB Life (2013) 0.78
Profound effects of the general anesthetic etomidate on oxidative phosphorylation without effects on their yield. J Bioenerg Biomembr (2006) 0.78
Monitoring metabolic responses of single mitochondria within poly(dimethylsiloxane) wells: study of their endogenous reduced nicotinamide adenine dinucleotide evolution. Anal Chem (2013) 0.77
Multilevel control of glucose homeostasis by adenylyl cyclase 8. Diabetologia (2014) 0.76
UCP1 as a water/proton co-transporter. Mitochondrion (2012) 0.76
Kinetic activation of yeast mitochondrial D-lactate dehydrogenase by carboxylic acids. Biochim Biophys Acta (2008) 0.75
PDMS microwells for multi-parametric monitoring of single mitochondria on a large scale: a study of their individual membrane potential and endogenous NADH. Integr Biol (Camb) (2016) 0.75