Published in J Mol Med (Berl) on September 01, 2010
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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells. PLoS One (2013) 1.29
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Energy metabolism plasticity enables stemness programs. Ann N Y Acad Sci (2012) 1.02
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To breathe or not to breathe: the haematopoietic stem/progenitor cells dilemma. Br J Pharmacol (2013) 0.91
The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming. Cell Cycle (2012) 0.91
Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate. Cancer Biol Ther (2012) 0.88
Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy. Front Physiol (2013) 0.88
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The effect of hypoxia on the stemness and differentiation capacity of PDLC and DPC. Biomed Res Int (2014) 0.87
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Increased Oxidative Stress as a Selective Anticancer Therapy. Oxid Med Cell Longev (2015) 0.83
Control of cell differentiation by mitochondria, typically evidenced in dictyostelium development. Biomolecules (2013) 0.83
Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells. EMBO Rep (2013) 0.83
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Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency. Stem Cell Res (2014) 0.82
Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria. PLoS One (2014) 0.81
Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation. PLoS One (2012) 0.81
Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication. PLoS One (2014) 0.80
IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations. FASEB J (2015) 0.80
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Neuronal differentiation involves a shift from glucose oxidation to fermentation. J Bioenerg Biomembr (2011) 0.79
Regulation of Stem Cell Fate by ROS-mediated Alteration of Metabolism. Int J Stem Cells (2015) 0.78
Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program. Stem Cells (2016) 0.78
Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function. Philos Trans R Soc Lond B Biol Sci (2012) 0.77
Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells. Oxid Med Cell Longev (2015) 0.76
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV. PLoS One (2014) 0.76
Biomaterial strategies for stem cell maintenance during in vitro expansion. Tissue Eng Part B Rev (2013) 0.76
Species diversity regarding the presence of proximal tubular progenitor cells of the kidney. Eur J Histochem (2016) 0.75
Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate. Aging (Albany NY) (2016) 0.75
Mechanisms Regulating Stemness and Differentiation in Embryonal Carcinoma Cells. Stem Cells Int (2017) 0.75
Accumulation of DNA damage in the aged hematopoietic stem cell compartment. Semin Hematol (2016) 0.75
Mitochondrial fission/fusion and cardiomyopathy. Curr Opin Genet Dev (2016) 0.75
Interruptin B induces brown adipocyte differentiation and glucose consumption in adipose-derived stem cells. Mol Med Rep (2016) 0.75
Mitochondrial-Shaping Proteins in Cardiac Health and Disease - the Long and the Short of It! Cardiovasc Drugs Ther (2017) 0.75
Mitochondria, oxidants, and aging. Cell (2005) 16.11
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell (2008) 10.34
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature (2008) 10.27
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell (2007) 9.20
The regulation of INK4/ARF in cancer and aging. Cell (2006) 8.75
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat Rev Genet (2008) 7.30
Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09
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Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest (2001) 6.59
Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol (2007) 6.33
Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation (2003) 6.30
Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer (2008) 6.02
Hypoxia-inducible factors, stem cells, and cancer. Cell (2007) 5.96
A fresh look at iPS cells. Cell (2009) 5.73
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A (2010) 4.97
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood (2007) 4.49
The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol (2008) 4.43
Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell (2009) 4.38
MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res (2009) 4.32
Low O2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci U S A (2005) 4.15
Targeting mitochondria for cancer therapy. Nat Rev Drug Discov (2010) 4.07
The promise of human induced pluripotent stem cells for research and therapy. Nat Rev Mol Cell Biol (2008) 3.56
Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells (2009) 3.46
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells (2010) 3.17
Mitochondria in cancer cells: what is so special about them? Trends Cell Biol (2008) 2.97
Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation (2009) 2.93
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell (2009) 2.72
Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan. Aging Cell (2007) 2.70
Formation of human myocardium in the rat heart from human embryonic stem cells. Am J Pathol (2005) 2.60
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell Stem Cell (2007) 2.56
Concise review: mesenchymal stromal cells: potential for cardiovascular repair. Stem Cells (2008) 2.39
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells (2008) 2.34
Mitochondrial reactive oxygen species-mediated signaling in endothelial cells. Am J Physiol Heart Circ Physiol (2007) 2.24
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Nat Clin Pract Cardiovasc Med (2007) 2.21
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation (2007) 2.21
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells (2010) 2.17
Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells. Biochem Biophys Res Commun (2006) 2.15
Mitochondrial DNA replication during differentiation of murine embryonic stem cells. J Cell Sci (2007) 1.98
Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia. Circulation (2007) 1.75
The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation. Stem Cell Rev (2009) 1.68
Differentiation-related changes in mitochondrial properties as indicators of stem cell competence. J Cell Physiol (2006) 1.49
Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell (2008) 1.47
Molecular basis of pluripotency. Hum Mol Genet (2008) 1.31
Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain. Stem Cell Res (2009) 1.23
Continuous hypoxic culturing maintains activation of Notch and allows long-term propagation of human embryonic stem cells without spontaneous differentiation. Cell Prolif (2009) 1.04
Sod2 overexpression preserves myoblast mitochondrial mass and function, but not muscle mass with aging. Aging Cell (2009) 0.93
Mechanisms that mediate stem cell self-renewal and differentiation. J Cell Biochem (2008) 0.86
Feeling the elephant of cardiovascular cell therapy. Circulation (2010) 0.79