Published in Nat Rev Mol Cell Biol on September 01, 2008
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells. J Clin Invest (2010) 3.09
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell (2010) 3.08
Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation (2009) 2.93
Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. PLoS One (2010) 2.86
Challenges with advanced therapy medicinal products and how to meet them. Nat Rev Drug Discov (2010) 2.09
Primary cilia and signaling pathways in mammalian development, health and disease. Nephron Physiol (2009) 2.09
Derivation of neural crest cells from human pluripotent stem cells. Nat Protoc (2010) 2.05
Pluripotency in the embryo and in culture. Cold Spring Harb Perspect Biol (2012) 1.93
Stepwise differentiation of pluripotent stem cells into retinal cells. Nat Protoc (2009) 1.88
Fully functional bioengineered tooth replacement as an organ replacement therapy. Proc Natl Acad Sci U S A (2009) 1.82
Stem cell-based therapies for spinal cord injury. J Spinal Cord Med (2009) 1.77
iPS programmed without c-MYC yield proficient cardiogenesis for functional heart chimerism. Circ Res (2009) 1.77
The potential landscape of genetic circuits imposes the arrow of time in stem cell differentiation. Biophys J (2010) 1.76
Toward clinical therapies using hematopoietic cells derived from human pluripotent stem cells. Blood (2009) 1.73
Present state and future perspectives of using pluripotent stem cells in toxicology research. Arch Toxicol (2011) 1.69
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells. Circulation (2010) 1.67
Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies. J Allergy Clin Immunol (2010) 1.65
Dedifferentiating spermatogonia outcompete somatic stem cells for niche occupancy in the Drosophila testis. Cell Stem Cell (2009) 1.61
Empowering self-renewal and differentiation: the role of mitochondria in stem cells. J Mol Med (Berl) (2010) 1.47
Reprogrammed cells for disease modeling and regenerative medicine. Annu Rev Med (2013) 1.45
Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells. Hum Mol Genet (2010) 1.40
Generation of induced pluripotent stem cells from human kidney mesangial cells. J Am Soc Nephrol (2011) 1.36
Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One (2011) 1.33
Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. J Clin Invest (2013) 1.31
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos Trans R Soc Lond B Biol Sci (2013) 1.26
Genetic control of wayward pluripotent stem cells and their progeny after transplantation. Cell Stem Cell (2009) 1.26
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proc Natl Acad Sci U S A (2011) 1.25
Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA. Biochem J (2012) 1.23
Stem cells in gastroenterology and hepatology. Nat Rev Gastroenterol Hepatol (2009) 1.23
Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation. Proc Natl Acad Sci U S A (2013) 1.21
Molecular genetics of tooth development. Curr Opin Genet Dev (2009) 1.20
Functional tooth regeneration using a bioengineered tooth unit as a mature organ replacement regenerative therapy. PLoS One (2011) 1.17
The challenge of immunogenicity in the quest for induced pluripotency. Nat Rev Immunol (2010) 1.14
microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. Cell Res (2012) 1.12
A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency. PLoS Comput Biol (2010) 1.08
c-MYC independent nuclear reprogramming favors cardiogenic potential of induced pluripotent stem cells. J Cardiovasc Transl Res (2010) 1.08
Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling. Stem Cells Transl Med (2012) 1.06
REST and the RESTless: in stem cells and beyond. Future Neurol (2009) 1.06
Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome - hope or hype? Crit Care (2012) 1.04
Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells. Cell Regen (Lond) (2013) 1.00
The potential for immunogenicity of autologous induced pluripotent stem cell-derived therapies. J Biol Chem (2013) 1.00
Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology. Dev Cell (2016) 0.99
Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells. Stem Cells (2010) 0.99
Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules. Biol Direct (2009) 0.98
Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor. Biomaterials (2013) 0.95
Effects of histocompatibility and host immune responses on the tumorigenicity of pluripotent stem cells. Semin Immunopathol (2011) 0.94
Biomaterial implants mediate autologous stem cell recruitment in mice. Acta Biomater (2011) 0.93
ROCK inhibition facilitates the generation of human-induced pluripotent stem cells in a defined, feeder-, and serum-free system. Cell Reprogram (2010) 0.92
Naive-like conversion overcomes the limited differentiation capacity of induced pluripotent stem cells. J Biol Chem (2013) 0.91
Low immunogenicity of neural progenitor cells differentiated from induced pluripotent stem cells derived from less immunogenic somatic cells. PLoS One (2013) 0.91
Lessons from the embryonic neural stem cell niche for neural lineage differentiation of pluripotent stem cells. Stem Cell Rev (2012) 0.90
An efficient and easy-to-use cryopreservation protocol for human ES and iPS cells. Nat Protoc (2010) 0.90
Ekiden to iPS Cells. Nat Med (2009) 0.89
Bioreactor engineering of stem cell environments. Biotechnol Adv (2013) 0.88
Induced pluripotent stem cells: advances to applications. Stem Cells Cloning (2010) 0.88
Proof of concept for AAV2/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient. Mol Ther Methods Clin Dev (2014) 0.88
Transitions between epithelial and mesenchymal states during cell fate conversions. Protein Cell (2014) 0.87
The 5-hydroxytryptamine 4 Receptor Agonist-induced Actions and Enteric Neurogenesis in the Gut. J Neurogastroenterol Motil (2013) 0.87
Imaging of Induced Pluripotent Stem Cells: From Cellular Reprogramming to Transplantation. Am J Nucl Med Mol Imaging (2011) 0.87
Recent developments in StemBase: a tool to study gene expression in human and murine stem cells. BMC Res Notes (2009) 0.86
Stem Cell Therapy in Acute Myocardial Infarction: A Pot of Gold or Pandora's Box. Stem Cells Int (2011) 0.86
MicroRNA-199b Modulates Vascular Cell Fate During iPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling. Stem Cells (2015) 0.84
A simple and highly effective method for slow-freezing human pluripotent stem cells using dimethyl sulfoxide, hydroxyethyl starch and ethylene glycol. PLoS One (2014) 0.84
In vitro pre-vascularisation of tissue-engineered constructs A co-culture perspective. Vasc Cell (2014) 0.84
Pre-transplantation specification of stem cells to cardiac lineage for regeneration of cardiac tissue. Stem Cell Rev (2009) 0.83
Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. PLoS One (2015) 0.83
The science and ethics of induced pluripotency: what will become of embryonic stem cells? Mayo Clin Proc (2011) 0.83
The pharmacology of regenerative medicine. Pharmacol Rev (2013) 0.83
Generation and characterization of human cryptorchid-specific induced pluripotent stem cells from urine. Stem Cells Dev (2013) 0.83
Human endometrial cells express elevated levels of pluripotent factors and are more amenable to reprogramming into induced pluripotent stem cells. Endocrinology (2011) 0.82
Banking on iPSC--is it doable and is it worthwhile. Stem Cell Rev (2015) 0.82
Human iPS cell-derived insulin producing cells form vascularized organoids under the kidney capsules of diabetic mice. PLoS One (2015) 0.82
HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol (2017) 0.82
Establishment of transgene-free induced pluripotent stem cells reprogrammed from human stem cells of apical papilla for neural differentiation. Stem Cell Res Ther (2012) 0.81
Equivalency of buffalo (Bubalus bubalis) embryonic stem cells derived from fertilized, parthenogenetic, and hand-made cloned embryos. Cell Reprogram (2012) 0.81
Antitumor effects of CD40 ligand-expressing endothelial progenitor cells derived from human induced pluripotent stem cells in a metastatic breast cancer model. Stem Cells Transl Med (2014) 0.80
A Closer Look at Schlemm's Canal Cell Physiology: Implications for Biomimetics. J Funct Biomater (2015) 0.80
Induced Pluripotent Stem Cells-A New Foundation in Medicine. J Exp Clin Med (2010) 0.79
Isolating single cells in a neurosphere assay using inertial microfluidics. Lab Chip (2015) 0.79
Generation of thyroid follicular cells from pluripotent stem cells: potential for regenerative medicine. Front Endocrinol (Lausanne) (2014) 0.79
The importance of stem cell engineering in head and neck oncology. Biotechnol Lett (2016) 0.79
A synthetic substrate to support early mesodermal differentiation of human embryonic stem cells. Biomaterials (2011) 0.78
MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state. PLoS One (2013) 0.78
Make room for dedifferentiation. Fly (Austin) (2009) 0.78
Modeling psychiatric disorders: from genomic findings to cellular phenotypes. Mol Psychiatry (2016) 0.78
Differentiation of human induced pluripotent stem cells into a keratinocyte lineage. Methods Mol Biol (2014) 0.77
Reduced immunogenicity of induced pluripotent stem cells derived from Sertoli cells. PLoS One (2014) 0.77
Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo. Cell Regen (Lond) (2015) 0.77
Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4. Stem Cells Int (2015) 0.77
Induced pluripotent stem cells in dermatology: potentials, advances, and limitations. Cold Spring Harb Perspect Med (2014) 0.77
Comparative analysis of nuclear transfer embryo-derived mouse embryonic stem cells. Part I: cellular characterization. Cell Reprogram (2011) 0.76
Induced pluripotent stem cells: how they will change the practice of cardiovascular medicine. Methodist Debakey Cardiovasc J (2013) 0.76
Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype. Mech Dev (2013) 0.76
Comparison of Cardiomyocyte Differentiation Potential Between Type 1 Diabetic Donor- and Nondiabetic Donor-Derived Induced Pluripotent Stem Cells. Cell Transplant (2015) 0.76
FoxO3a contributes to the reprogramming process and the differentiation of induced pluripotent stem cells. Stem Cells Dev (2013) 0.76
Can pluripotent stem cells be used in cell-based therapy? Cell Reprogram (2014) 0.76
Stem cells: holding on to the memories. Nat Rev Mol Cell Biol (2010) 0.76
Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease. Exp Mol Med (2016) 0.75
Induced autologous stem cell transplantation for treatment of rabbit renal interstitial fibrosis. PLoS One (2013) 0.75
Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes. J Am Soc Nephrol (2006) 3.12
New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell (2008) 2.61
A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3. Diabetes (2008) 2.51
Genetics of type 1 diabetes: what's next? Diabetes (2010) 1.80
The Juvenile Diabetes Research Foundation at forty: updates of research in type 1 diabetes. Diabetes (2010) 0.87
Do stem cell-derived islets represent a commercially viable treatment for Type 1 and 2 diabetes? Regen Med (2010) 0.79
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