Published in J Hepatol on August 01, 2010
Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J Hepatol (2013) 2.14
Obesity, inflammation, and liver cancer. J Hepatol (2011) 2.09
Integration of cellular bioenergetics with mitochondrial quality control and autophagy. Biol Chem (2012) 2.08
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy. Mediators Inflamm (2013) 1.80
Organotypic liver culture models: meeting current challenges in toxicity testing. Crit Rev Toxicol (2012) 1.46
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy. Cell Death Differ (2011) 1.32
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. J Clin Invest (2012) 1.29
Autophagy protects against palmitate-induced apoptosis in hepatocytes. Cell Biosci (2014) 1.23
The emerging role of autophagy in alcoholic liver disease. Exp Biol Med (Maywood) (2011) 1.13
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224. Hepatology (2013) 1.12
Autophagy: a cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress. Autophagy (2012) 1.08
Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis. World J Gastroenterol (2011) 1.06
Liver autophagy: much more than just taking out the trash. Nat Rev Gastroenterol Hepatol (2013) 1.05
Autophagy: a multifaceted partner in liver fibrosis. Biomed Res Int (2014) 1.05
Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase. Cell Death Dis (2013) 1.01
Targeting autophagy for the treatment of liver diseases. Pharmacol Res (2012) 1.01
Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. Free Radic Biol Med (2012) 0.99
MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R. Oncotarget (2014) 0.99
The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease. Toxicol Sci (2013) 0.98
CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2. Cell Death Dis (2014) 0.96
Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy. Am J Physiol Gastrointest Liver Physiol (2012) 0.95
Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. Redox Biol (2013) 0.94
Remote ischemic preconditioning protects against liver ischemia-reperfusion injury via heme oxygenase-1-induced autophagy. PLoS One (2014) 0.93
Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics. Biochem Soc Trans (2013) 0.93
Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX. Liver Int (2013) 0.90
Changes in autophagic response in patients with chronic hepatitis C virus infection. Am J Pathol (2011) 0.89
Hepatic differentiation and maturation of human embryonic stem cells cultured in a perfused three-dimensional bioreactor. Stem Cells Dev (2012) 0.88
Primary hepatocytes and their cultures in liver apoptosis research. Arch Toxicol (2013) 0.88
Autophagy and liver ischemia-reperfusion injury. Biomed Res Int (2015) 0.88
Autophagy modulation as a potential therapeutic target for liver diseases. J Clin Exp Hepatol (2014) 0.87
mTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment. World J Transplant (2013) 0.87
Endoplasmic reticulum is at the crossroads of autophagy, inflammation, and apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus. J Diabetes Res (2013) 0.86
Physiological and pathophysiological roles for phospholipase D. J Lipid Res (2015) 0.86
Liver autophagy in anorexia nervosa and acute liver injury. Biomed Res Int (2014) 0.85
Autophagy: A novel therapeutic target for hepatocarcinoma (Review). Oncol Lett (2014) 0.84
Impaired autophagy response in human hepatocellular carcinoma. Exp Mol Pathol (2013) 0.84
Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. Pflugers Arch (2013) 0.84
Polyethylene glycol rinse solution: an effective way to prevent ischemia-reperfusion injury. World J Gastroenterol (2014) 0.83
Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis (2014) 0.83
Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD). Chin Med (2014) 0.82
The regulation of the autophagic network and its implications for human disease. Int J Biol Sci (2013) 0.82
Ethanol-induced oxidant stress modulates hepatic autophagy and proteasome activity. Redox Biol (2014) 0.82
Autophagy Protects against CYP2E1/Chronic Ethanol-Induced Hepatotoxicity. Biomolecules (2015) 0.81
Mitigation of autophagy ameliorates hepatocellular damage following ischemia-reperfusion injury in murine steatotic liver. Am J Physiol Gastrointest Liver Physiol (2014) 0.81
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy. Int J Mol Sci (2015) 0.81
Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes. World J Gastroenterol (2016) 0.81
Efficacy of MK615 for the treatment of patients with liver disorders. World J Gastroenterol (2012) 0.80
Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression. J Lipid Res (2012) 0.80
Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer. Oncotarget (2016) 0.80
GADD45β induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia. Oncotarget (2016) 0.79
Mechanisms of fibrosis in acute liver failure. Liver Int (2015) 0.79
Autophagy: a new target for nonalcoholic fatty liver disease therapy. Hepat Med (2016) 0.79
Cross-talk between the thyroid and liver: a new target for nonalcoholic fatty liver disease treatment. World J Gastroenterol (2013) 0.79
Hyperoxia fully protects mitochondria of explanted livers. J Bioenerg Biomembr (2011) 0.79
Knockdown of linc-POU3F3 suppresses the proliferation, apoptosis, and migration resistance of colorectal cancer. Oncotarget (2016) 0.79
The Dichotomy of Endoplasmic Reticulum Stress Response in Liver Ischemia-Reperfusion Injury. Transplantation (2016) 0.78
Activation of autophagy protects against cholestasis-induced hepatic injury. Cell Biosci (2014) 0.78
Autophagy Constitutes a Protective Mechanism against Ethanol Toxicity in Mouse Astrocytes and Neurons. PLoS One (2016) 0.78
Baicalein pretreatment reduces liver ischemia/reperfusion injury via induction of autophagy in rats. Sci Rep (2016) 0.78
ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds. Am J Cancer Res (2016) 0.78
Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease. Mol Med Rep (2016) 0.77
The Role of Autophagy in Hepatocellular Carcinoma. Int J Mol Sci (2015) 0.77
Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy. Oncotarget (2016) 0.77
Transforming growth factor‑β1 reduces apoptosis via autophagy activation in hepatic stellate cells. Mol Med Rep (2014) 0.77
Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep (2015) 0.77
Autophagy in anti-apoptotic effect of augmenter of liver regeneration in HepG2 cells. World J Gastroenterol (2015) 0.77
Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors. Sci Rep (2016) 0.76
Autophagy protects against dasatinib-induced hepatotoxicity via p38 signaling. Oncotarget (2015) 0.76
Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy. Sci Rep (2016) 0.76
Zebrafish as a disease model for studying human hepatocellular carcinoma. World J Gastroenterol (2015) 0.76
Retinoic acid receptor α promotes autophagy to alleviate liver ischemia and reperfusion injury. World J Gastroenterol (2015) 0.76
Biliary epithelial senescence and plasticity in acute cellular rejection. Am J Transplant (2013) 0.76
Rapamycin enhances HBV production by inducing cellular autophagy. Hepat Mon (2014) 0.76
Role of Protein Quality Control Failure in Alcoholic Hepatitis Pathogenesis. Biomolecules (2017) 0.75
miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate. World J Gastroenterol (2016) 0.75
Autophagy and liver disease. J Clin Exp Hepatol (2013) 0.75
Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts. Front Physiol (2016) 0.75
Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti-fibrosis effect by inhibition of mammalian target of rapamycin. J Cell Mol Med (2016) 0.75
Ischemic preconditioning attenuates ischemia/reperfusion injury in rat steatotic liver: role of heme oxygenase-1-mediated autophagy. Oncotarget (2016) 0.75
Identification of natural products with neuronal and metabolic benefits through autophagy induction. Autophagy (2016) 0.75
Capillary Electrophoresis with Laser-Induced Fluorescent Detection of Immunolabeled Individual Autophagy Organelles Isolated from Liver Tissue. Anal Chem (2016) 0.75
Lactobacillus fermentum Postbiotic-induced Autophagy as Potential Approach for Treatment of Acetaminophen Hepatotoxicity. Front Microbiol (2017) 0.75
Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response. Autophagy (2016) 0.75
Autophagy Determines Efficiency of Liver-directed Gene Therapy with Adeno-associated Viral Vectors. Hepatology (2017) 0.75
The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Autophagy (2017) 0.75
Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells. Sci Rep (2017) 0.75
Early liver transplantation for severe alcoholic hepatitis. N Engl J Med (2011) 8.50
Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites. Hepatology (2010) 8.11
Clinical classification of pulmonary hypertension. J Am Coll Cardiol (2004) 5.87
Enoxaparin prevents portal vein thrombosis and liver decompensation in patients with advanced cirrhosis. Gastroenterology (2012) 5.75
Diagnostic accuracy of the Multistix 8 SG reagent strip in diagnosis of spontaneous bacterial peritonitis. Hepatology (2007) 3.75
Acute-on chronic liver failure. J Hepatol (2012) 3.74
Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis. Gastroenterology (2007) 3.61
The "50-50 criteria" on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy. Ann Surg (2005) 3.46
Amanita phalloides poisoning: reassessment of prognostic factors and indications for emergency liver transplantation. J Hepatol (2006) 3.14
The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. Hepatology (2003) 3.00
Early serum HBsAg drop: a strong predictor of sustained virological response to pegylated interferon alfa-2a in HBeAg-negative patients. Hepatology (2009) 2.97
Acute portal vein thrombosis unrelated to cirrhosis: a prospective multicenter follow-up study. Hepatology (2010) 2.82
Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis. Gut (2011) 2.65
Beta-blockers cause paracentesis-induced circulatory dysfunction in patients with cirrhosis and refractory ascites: a cross-over study. J Hepatol (2011) 2.59
Diagnosis of portopulmonary hypertension in candidates for liver transplantation: a prospective study. Hepatology (2003) 2.57
Impact of peginterferon and ribavirin therapy on hepatocellular carcinoma: incidence and survival in hepatitis C patients with advanced fibrosis. J Hepatol (2010) 2.43
Portal cavernoma-associated cholangiopathy: a clinical and MR cholangiography coupled with MR portography imaging study. Hepatology (2003) 2.43
Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. J Pharmacol Exp Ther (2005) 2.41
EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002 Geneva, Switzerland. Consensus statement (long version). J Hepatol (2003) 2.37
Severe sepsis in cirrhosis. Hepatology (2009) 2.33
Refractory ascites: pathogenesis, definition and therapy of a severe complication in patients with cirrhosis. Liver Int (2010) 2.32
TIPS for Budd-Chiari syndrome: long-term results and prognostics factors in 124 patients. Gastroenterology (2008) 2.25
Prospective comparison of spleen and liver stiffness by using shear-wave and transient elastography for detection of portal hypertension in cirrhosis. Radiology (2014) 2.22
The evaluation of renal function and disease in patients with cirrhosis. J Hepatol (2010) 2.10
Risk factors for Enterobacteriaceae bacteremia after liver transplantation. Transpl Int (2008) 2.06
Terlipressin in patients with cirrhosis and type 1 hepatorenal syndrome: a retrospective multicenter study. Gastroenterology (2002) 2.06
Resection prior to liver transplantation for hepatocellular carcinoma. Ann Surg (2003) 2.03
Assessment of the prognosis of cirrhosis: Child-Pugh versus MELD. J Hepatol (2004) 2.01
IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C. J Hepatol (2011) 1.97
Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA (2013) 1.94
Cirrhotic patients in the medical intensive care unit: early prognosis and long-term survival. Crit Care Med (2010) 1.94
Microbial epidemiology and outcome of bloodstream infections in liver transplant recipients: an analysis of 259 episodes. Liver Transpl (2010) 1.81
Evidence for a role of nonalcoholic steatohepatitis in hepatitis C: a prospective study. Hepatology (2007) 1.81
Diabetes mellitus is an independent prognostic factor for major liver-related outcomes in patients with cirrhosis and chronic hepatitis C. Hepatology (2014) 1.81
Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. Hepatology (2003) 1.79
The spectrum of renal lesions in patients with cirrhosis: a clinicopathological study. Liver Int (2009) 1.76
Portopulmonary hypertension: survival and prognostic factors. Am J Respir Crit Care Med (2008) 1.71
A single-center surgical experience of 122 patients with single and multiple hepatocellular adenomas. Gastroenterology (2009) 1.70
Abnormal plasma microparticles impair vasoconstrictor responses in patients with cirrhosis. Gastroenterology (2012) 1.69
Management of critically-ill cirrhotic patients. J Hepatol (2012) 1.65
Benefit of initial resection of hepatocellular carcinoma followed by transplantation in case of recurrence: an intention-to-treat analysis. Hepatology (2012) 1.64
Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89-IgA and IgG-IgA complexes: common mechanisms for distinct diseases. Kidney Int (2011) 1.64
Histologic scoring of liver biopsy in focal nodular hyperplasia with atypical presentation. Hepatology (2002) 1.55
Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PLoS One (2010) 1.54
High-density lipoprotein administration attenuates liver proinflammatory response, restores liver endothelial nitric oxide synthase activity, and lowers portal pressure in cirrhotic rats. Hepatology (2007) 1.50
Meta-analyses of FibroTest diagnostic value in chronic liver disease. BMC Gastroenterol (2007) 1.49
Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C. Gastroenterology (2005) 1.48
Long-term outcome of hepatitis C infection after bone marrow transplantation. Blood (2003) 1.45
Cardiac hepatopathy: clinical, hemodynamic, and histologic characteristics and correlations. Hepatology (2003) 1.42
Noninvasive assessment of portal hypertension in patients with cirrhosis. Hepatology (2011) 1.42
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C. J Pathol (2010) 1.41
Lack of prognostic usefulness of hepatic venous pressures and hemodynamic values in a select group of patients with severe alcoholic cirrhosis. Am J Gastroenterol (2002) 1.39
Liver transplantation for hepatocellular carcinoma: should we push the limits? Liver Transpl (2003) 1.39
10-Fold increase (2006-11) in the rate of healthy subjects with extended-spectrum β-lactamase-producing Escherichia coli faecal carriage in a Parisian check-up centre. J Antimicrob Chemother (2012) 1.39
Assessment of prognosis of cirrhosis. Semin Liver Dis (2008) 1.38
Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice. Gastroenterology (2002) 1.35
Prevention of gram-negative translocation reduces the severity of hepatopulmonary syndrome. Am J Respir Crit Care Med (2002) 1.34
Aiming at minimal invasiveness as a therapeutic strategy for Budd-Chiari syndrome. Hepatology (2006) 1.34
Acute liver cell damage in patients with anorexia nervosa: a possible role of starvation-induced hepatocyte autophagy. Gastroenterology (2008) 1.34
Model for end-stage liver disease score and systemic inflammatory response are major prognostic factors in patients with cirrhosis and acute functional renal failure. Hepatology (2007) 1.33
Acute renal failure in patients with cirrhosis: perspectives in the age of MELD. Hepatology (2003) 1.32