Published in Am J Pathol on September 09, 2010
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Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer. BMC Cancer (2012) 1.30
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Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA (2008) 12.26
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene (2007) 10.79
Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol (2008) 10.28
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Detection of microRNA expression in human peripheral blood microvesicles. PLoS One (2008) 8.04
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol (2008) 7.86
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MicroRNA-143 regulates adipocyte differentiation. J Biol Chem (2004) 6.78
Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer (2006) 6.39
Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int J Cancer (2010) 5.57
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A (2007) 5.50
MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell (2008) 5.34
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology (2008) 4.38
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci U S A (2007) 3.92
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res (2008) 3.81
A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. Urol Oncol (2009) 3.59
Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem (2007) 2.55
The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer (2008) 2.52
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene (2009) 2.49
MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers. Oncol Rep (2006) 2.29
MicroRNA-143 and -145 in colon cancer. DNA Cell Biol (2007) 2.24
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun (2008) 2.08
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation. Mol Syst Biol (2008) 2.04
Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Dis Markers (2009) 2.02
Non-coding MicroRNAs hsa-let-7g and hsa-miR-181b are Associated with Chemoresponse to S-1 in Colon Cancer. Cancer Genomics Proteomics (2006) 1.94
miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. Clin Cancer Res (2008) 1.87
Deregulated expression of miR-106a predicts survival in human colon cancer patients. Genes Chromosomes Cancer (2008) 1.75
High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells. World J Gastroenterol (2009) 1.62
MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. FEBS J (2009) 1.54
Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue. Cancer Genomics Proteomics (2009) 1.41
Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro. Pharmacol Res (2007) 1.37
Concepts in in vivo siRNA delivery for cancer therapy. J Cell Physiol (2009) 0.98
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study. Lancet Oncol (2010) 2.09
Significant antitumor effect from bone-seeking, alpha-particle-emitting (223)Ra demonstrated in an experimental skeletal metastases model. Cancer Res (2002) 1.77
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics (2003) 1.35
Matrix metalloproteinases participate in osteosarcoma invasion. J Surg Res (2005) 1.32
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer. BMC Cancer (2012) 1.30
Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice. Eur J Cancer (2004) 1.28
Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma. Clin Cancer Res (2003) 1.26
Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer. J Pathol (2003) 1.23
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLoS One (2013) 1.22
Circulating tumor cells in the peripheral blood and bone marrow of patients with ovarian carcinoma do not predict prognosis. Cancer (2002) 1.13
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition. Radiat Oncol (2006) 1.13
Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling. Int J Radiat Oncol Biol Phys (2010) 1.13
Early changes in apparent diffusion coefficient predict the quantitative antitumoral activity of capecitabine, oxaliplatin, and irradiation in HT29 xenografts in athymic nude mice. Neoplasia (2007) 1.08
Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer. Clin Colorectal Cancer (2013) 1.08
Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin. Int J Cancer (2004) 1.07
Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum. Tumour Biol (2004) 1.05
Radiosensitization by SAHA in experimental colorectal carcinoma models-in vivo effects and relevance of histone acetylation status. Int J Radiat Oncol Biol Phys (2009) 1.05
Immunomagnetic detection of micrometastatic cells in bone marrow of colorectal cancer patients. Clin Cancer Res (2002) 1.04
B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer. Int J Cancer (2012) 1.01
Nuclear S100A4 is a novel prognostic marker in colorectal cancer. Eur J Cancer (2010) 0.99
Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma. Mod Pathol (2004) 0.98
Cystatin E/M suppresses legumain activity and invasion of human melanoma. BMC Cancer (2010) 0.97
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Nuclear legumain activity in colorectal cancer. PLoS One (2013) 0.95
Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4. BMC Cancer (2004) 0.93
Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma. PLoS One (2011) 0.92
Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles. Breast Cancer Res (2011) 0.92
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells. Pigment Cell Melanoma Res (2010) 0.91
A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth. Cancer Immunol Immunother (2010) 0.90
Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice. Int J Cancer (2004) 0.89
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial. Trials (2015) 0.89
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Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy. Radiat Oncol (2011) 0.88
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1. Oncogene (2003) 0.87
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients. Lung Cancer (2008) 0.87
Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients. Clin Cancer Res (2004) 0.87
Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity? Radiother Oncol (2007) 0.86
Different expression and clinical role of S100A4 in serous ovarian carcinoma at different anatomic sites. Tumour Biol (2009) 0.86
B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome. BMC Cancer (2014) 0.86
AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death. Mol Cancer Ther (2006) 0.86
Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients. Acta Ophthalmol (2009) 0.85
Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype. BMC Cancer (2007) 0.85
Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells. Int J Cancer (2002) 0.85
Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination. Angiogenesis (2011) 0.85
HDAC2 deficiency and histone acetylation. Nat Genet (2008) 0.84
Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer. Int J Radiat Oncol Biol Phys (2013) 0.84
Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma. Radiat Oncol (2012) 0.83
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies. Int J Cancer (2013) 0.83
Inhibition of in vivo tumour growth by the blocking of host alpha(v)beta3 and alphaII(b)beta3 integrins. Anticancer Res (2009) 0.82
The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications. BMC Cancer (2008) 0.81
Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling. Clin Exp Metastasis (2009) 0.81
Bone marrow micrometastases studied by an immunomagnetic isolation procedure in extremity localized non-metastatic osteosarcoma patients. Cancer Treat Res (2009) 0.81
The melanoma specific 9.2.27PE immunotoxin efficiently kills melanoma cells in vitro. Int J Cancer (2009) 0.81
Plasminogen activator inhibitor-1 increases the expression of VEGF in human glioma cells. Exp Cell Res (2004) 0.80
Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts. Int J Cancer (2011) 0.80
Detection of disseminated tumour cells in bone marrow of patients with isolated liver metastases from colorectal cancer. J Surg Oncol (2003) 0.79
The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells. J Ovarian Res (2014) 0.78
Impact of hyperthermia on pharmacokinetics of intraperitoneal mitomycin C in rats investigated by microdialysis. J Surg Oncol (2013) 0.78
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting. Anticancer Res (2006) 0.77
Rab25 is overexpressed in Müllerian serous carcinoma compared to malignant mesothelioma. Virchows Arch (2012) 0.77
MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy. Radiother Oncol (2009) 0.76
Radiosensitizing drugs: lessons to be learned from the oxaliplatin story. J Clin Oncol (2010) 0.76
Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox. Acta Ophthalmol (2015) 0.76
Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer. PLoS One (2012) 0.75
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles. Cancer Gene Ther (2005) 0.75
Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study. BMC Cancer (2010) 0.75
Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma. Amino Acids (2010) 0.75
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients. Melanoma Res (2008) 0.75
Investigation of nonspecific cross-reacting antigen 2 as a prognostic biomarker in bone marrow plasma from colorectal cancer patients. Tumour Biol (2011) 0.75
TD-11 workshop report: characterization of monoclonal antibodies to S100 proteins. Tumour Biol (2010) 0.75
A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer. NAR Cancer (2022) 0.75
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial. Ann Surg (2017) 0.75
Disseminated tumour cells in bone marrow of patients with uveal melanoma. Acta Ophthalmol (2012) 0.75