MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.

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Published in Oncogene on October 29, 2007

Authors

I A Asangani1, S A K Rasheed, D A Nikolova, J H Leupold, N H Colburn, S Post, H Allgayer

Author Affiliations

1: Department of Experimental Surgery and Molecular Oncology of Solid Tumors, Medical Faculty Mannheim, University of Heidelberg, Germany.

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A (1994) 2.43

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Effects of antacids on the clinical pharmacokinetics of drugs. An update. Clin Pharmacokinet (1990) 1.23

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PCR-direct sequencing of a GC-rich region by inclusion of 10% DMSO: application to mouse c-jun. Biotechniques (1993) 1.13

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis. Gene Ther (2009) 1.11

Role of microcirculatory derangements in manifestation of portal triad cross-clamping-induced hepatic reperfusion injury. J Surg Res (1996) 1.11

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Local excision of early rectal cancer: is transanal endoscopic microsurgery an alternative to radical surgery? Rev Esp Enferm Dig (2009) 1.00

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Tumor-promoting phorbol esters inhibit procollagen synthesis at a pretranslational level in JB-6 mouse epidermal cells. Mol Cell Biol (1983) 1.00

Dosage-dependent dominance over wild-type p53 of a mutant p53 isolated from nasopharyngeal carcinoma. FASEB J (1993) 1.00

Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation. J Biol Chem (1995) 0.99

Differential c-jun expression in response to tumor promoters in JB6 cells sensitive or resistant to neoplastic transformation. Mol Carcinog (1992) 0.98

Tumor promotion and preneoplastic progression. Carcinog Compr Surv (1980) 0.98

Extrahepatic biliary obstruction impairs microvascular perfusion and increases leukocyte adhesion in rat liver. Hepatology (1997) 0.97

Tumor-associated proteolysis and prognosis: new functional risk factors in gastric cancer defined by the urokinase-type plasminogen activator system. J Clin Oncol (1995) 0.97

Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA. Carcinogenesis (1985) 0.97

Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells. FASEB J (1998) 0.96

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Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor. Eur J Biochem (2000) 0.96

Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines. Ann N Y Acad Sci (1981) 0.96

Drug-induced fibrosing colonopathy in inflammatory bowel disease after 5-ASA? Dig Dis Sci (1999) 0.95

Four-day duration of tumor promoter exposure required to transform JB6 promotion-sensitive cells to anchorage independence. Cancer Res (1988) 0.95

Biodegradation of absorbable sutures in body fluids and pH buffers. Eur Surg Res (2004) 0.94

A family of mitogen-activated protein kinase-related proteins interacts in vivo with activator protein-1 transcription factor. J Biol Chem (1994) 0.93

Nasopharyngeal carcinoma shows no detectable retinoblastoma susceptibility gene alterations. Oncogene (1993) 0.93

Studies of the reaction of beta-propiolactone with deoxyguanosine and related compounds. Biochem Pharmacol (1965) 0.92

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Ileus secondary to wireless capsule enteroscopy. Int J Colorectal Dis (2006) 0.91

Impact of N-acetylcysteine on the hepatic microcirculation after orthotopic liver transplantation. Transplantation (1996) 0.91

Role of cytoskeleton changes and expression of the H-ras oncogene during promotion of neoplastic transformation in mouse epidermal JB6 cells. Cancer Res (1986) 0.90

Is delayed gastric emptying following pancreaticoduodenectomy related to pylorus preservation? Langenbecks Arch Surg (1999) 0.90

Clostridial gas gangrene of the abdominal wall after laparoscopic cholecystectomy. J Laparoendosc Adv Surg Tech A (1997) 0.90

Malignant intestinal non-Hodgkin's lymphoma from the surgical point of view. Onkologie (2002) 0.90

Inhibition of nitric oxide synthesis in ischemia/reperfusion of the rat liver is followed by impairment of hepatic microvascular blood flow. J Hepatol (1997) 0.90

C-JUN/AP-1 as possible mediators of tumor necrosis factor-alpha-induced apoptotic response in mouse JB6 tumor cells. Oncol Res (1995) 0.90

Influence of autologous blood transfusion on natural killer and lymphokine-activated killer cell activities in cancer surgery. Vox Sang (1997) 0.90

Early superoxide dismutase-sensitive event promotes neoplastic transformation in mouse epidermal JB6 cells. Carcinogenesis (1988) 0.90

Selective fluid cushion in the submucosal layer by water jet: advantage for endoscopic mucosal resection. Eur Surg Res (2007) 0.89

Effect of olsalazine and mesalazine on human ileal and colonic (Na+ + K+)-ATPase. A possible diarrhogenic factor? Clin Investig (1993) 0.89

Involvement of Ras/Raf/AP-1 in BMP-4 signaling during Xenopus embryonic development. Proc Natl Acad Sci U S A (1996) 0.89

Prognostic influence of blood transfusion on minimal residual disease in resected gastric cancer patients. Anticancer Res (1997) 0.89

A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor. Eur J Biochem (1999) 0.89

Retrorectal tumors: excision by transanal endoscopic microsurgery. Rev Esp Enferm Dig (2007) 0.89

Impact of gastrin-releasing peptide on intestinal microcirculation after ischemia-reperfusion in rats. Digestion (2000) 0.89

Differential transformation efficiency but not AP-1 induction under anchorage-dependent and -independent conditions. Carcinogenesis (1994) 0.89

Endoscopic full-thickness resection of the stomach: an experimental approach. Surg Endosc (2006) 0.88

[Open abdomen 2009. A national survey of open abdomen treatment in Germany]. Chirurg (2011) 0.88