Published in Clin Exp Metastasis on September 16, 2010
Exosomes: a novel pathway of local and distant intercellular communication that facilitates the growth and metastasis of neoplastic lesions. Am J Pathol (2013) 1.54
In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model. BMC Cancer (2011) 1.21
Metastasis suppressor genes at the interface between the environment and tumor cell growth. Int Rev Cell Mol Biol (2011) 1.18
Metastasis suppressors and the tumor microenvironment. Semin Cancer Biol (2010) 1.03
Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo. Clin Cancer Res (2015) 0.94
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice. Clin Exp Metastasis (2012) 0.92
S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase. Sci Rep (2015) 0.91
Non-invasive molecular imaging for preclinical cancer therapeutic development. Br J Pharmacol (2013) 0.91
βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancer. Oncotarget (2015) 0.90
Targeted noninvasive imaging of EGFR-expressing orthotopic pancreatic cancer using multispectral optoacoustic tomography. Cancer Res (2014) 0.87
Clinical and biological significance of KISS1 expression in prostate cancer. Am J Pathol (2012) 0.85
Orthotopic pancreatic tumors detected by optoacoustic tomography using Syndecan-1. J Surg Res (2014) 0.82
Detection of Phosphatidylcholine-Coated Gold Nanoparticles in Orthotopic Pancreatic Adenocarcinoma using Hyperspectral Imaging. PLoS One (2015) 0.80
KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway. Eur J Histochem (2013) 0.80
Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography. J Nanobiotechnology (2015) 0.79
Predictive modeling of in vivo response to gemcitabine in pancreatic cancer. PLoS Comput Biol (2013) 0.79
Development of orthotopic pancreatic tumor mouse models. Methods Mol Biol (2013) 0.79
Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomography. ACS Biomater Sci Eng (2016) 0.78
Clinical significance of KISS1 protein expression for brain invasion and metastasis. Cancer (2011) 0.78
Suppression of pancreatic cancer growth and metastasis by HMP19 identified through genome-wide shRNA screen. Int J Cancer (2016) 0.77
Genomics screens for metastasis genes. Cancer Metastasis Rev (2012) 0.77
Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice. Pancreas (2015) 0.76
KiSS‑1‑mediated suppression of the invasive ability of human pancreatic carcinoma cells is not dependent on the level of KiSS‑1 receptor GPR54. Mol Med Rep (2015) 0.75
Cancer statistics, 2009. CA Cancer J Clin (2009) 83.57
Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev (2006) 8.26
KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst (1996) 4.16
Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer (2003) 3.96
Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem (2000) 2.53
A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer. Br J Cancer (2002) 2.53
Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res (1997) 2.27
Novel functions of TIMPs in cell signaling. Cancer Metastasis Rev (2006) 2.26
Neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreas: treatment variables and survival duration. Ann Surg Oncol (2001) 2.24
Surgery for pancreatic cancer: recent controversies and current practice. Gastroenterology (2005) 1.78
Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy. J Natl Cancer Inst (2007) 1.78
Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application. Clin Cancer Res (2006) 1.75
Metastasis suppressors genes in cancer. Int J Biochem Cell Biol (2008) 1.67
Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res (2002) 1.38
Metastin and its variant forms suppress migration of pancreatic cancer cells. Biochem Biophys Res Commun (2004) 1.36
High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential. Biochem Biophys Res Commun (1999) 1.35
Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma. Int J Cancer (2004) 1.34
KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis (2005) 1.33
Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma. BMC Med (2007) 1.15
Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. Clin Cancer Res (2007) 1.14
Present treatment and future expectations in advanced pancreatic cancer. Anticancer Res (2008) 1.06
The missing kiss of life: transcriptional activity of the metastasis suppressor gene KiSS1 in early breast cancer. Anticancer Res (2007) 0.96
Prognostic value of metastin expression in human pancreatic cancer. J Exp Clin Cancer Res (2009) 0.94
Nm23 and tumour metastasis: basic and translational advances. Biochem Soc Symp (1998) 0.92
Pancreatic cancer: from molecular signature to target therapy. Crit Rev Oncol Hematol (2008) 0.92
High collagenolytic activity in spontaneously highly metastatic variants derived from a human pancreatic cancer cell line (SUIT-2) in nude mice. Clin Exp Metastasis (2000) 0.91
Clinical significance of plasma metastin level in pancreatic cancer patients. Oncol Rep (2009) 0.88
Metastasis: recent discoveries and novel treatment strategies. Lancet (2007) 3.93
Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res (2009) 3.40
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 3.12
SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res (2007) 2.98
Return of research results from genomic biobanks: cost matters. Genet Med (2012) 2.93
Modern age pathology of pulmonary arterial hypertension. Am J Respir Crit Care Med (2012) 2.68
Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer (2009) 2.64
Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res (2009) 2.45
SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer. Clin Chem (2007) 2.38
Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood (2007) 2.35
Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group. J Proteome Res (2009) 2.33
Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. Arthritis Rheum (2011) 2.33
Practical implementation issues and challenges for biobanks in the return of individual research results. Genet Med (2012) 2.32
Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Res (2007) 2.27
Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias. Clin Chem (2007) 2.23
Tumor exosomes inhibit differentiation of bone marrow dendritic cells. J Immunol (2007) 2.16
Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clin Cancer Res (2004) 2.02
Promoter hypermethylation profile of kidney cancer. Clin Cancer Res (2004) 2.02
CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest (2004) 2.01
Serum biomarker panels for the detection of pancreatic cancer. Clin Cancer Res (2011) 1.98
Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. J Biol Chem (2003) 1.98
The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. J Biol Chem (2005) 1.96
Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity. Cancer Res (2005) 1.92
Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. Clin Cancer Res (2002) 1.89
Antibody responses of variable lymphocyte receptors in the lamprey. Nat Immunol (2008) 1.87
A functional anatomic defect of the cystic fibrosis airway. Am J Respir Crit Care Med (2014) 1.85
Exosomes and cancer: a newly described pathway of immune suppression. Clin Cancer Res (2011) 1.83
Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma. Cancer (2004) 1.78
Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy. J Natl Cancer Inst (2007) 1.78
Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application. Clin Cancer Res (2006) 1.75
Thymus exosomes-like particles induce regulatory T cells. J Immunol (2008) 1.73
Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma. J Mol Diagn (2006) 1.70
Expression of sperm protein 17 (Sp17) in ovarian cancer. Int J Cancer (2004) 1.70
Suppression of human melanoma metastasis by the metastasis suppressor gene, BRMS1. Exp Cell Res (2002) 1.68
Metastasis suppressors genes in cancer. Int J Biochem Cell Biol (2008) 1.67
The Wnt/β-catenin pathway in ovarian cancer: a review. Gynecol Oncol (2013) 1.66
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer. J Biol Chem (2003) 1.66
Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia. Cancer Res (2007) 1.66
Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model. Clin Cancer Res (2003) 1.65
Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture. Breast Cancer Res (2004) 1.58
Breast cancer chemoprevention phase I evaluation of biomarker modulation by arzoxifene, a third generation selective estrogen receptor modulator. Clin Cancer Res (2004) 1.58
Metastasis suppressor pathways--an evolving paradigm. Cancer Lett (2003) 1.57
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5. Int J Radiat Oncol Biol Phys (2008) 1.56
Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography. PLoS One (2013) 1.56
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer. Cancer Biol Ther (2006) 1.55
Treatment with gemcitabine and TRA-8 anti-death receptor-5 mAb reduces pancreatic adenocarcinoma cell viability in vitro and growth in vivo. J Gastrointest Surg (2006) 1.50
BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process. Am J Pathol (2008) 1.46
Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP. Cancer Res (2003) 1.46
Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patients. Clin Cancer Res (2006) 1.45
ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib. Cancer Biol Ther (2007) 1.43
Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression. Int J Cancer (2009) 1.42
Kinetics of metastatic breast cancer cell trafficking in bone. Clin Cancer Res (2006) 1.42
Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance. Diabetes (2009) 1.42
A framework for biobank sustainability. Biopreserv Biobank (2014) 1.41
Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappaB activation. Mol Cancer (2007) 1.40
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Carcinogenesis (2011) 1.39
Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates. Am J Clin Pathol (2006) 1.39
Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells. J Biol Chem (2008) 1.34
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone. Biochem Biophys Res Commun (2006) 1.33
Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology (2009) 1.33
Genetic background is an important determinant of metastatic potential. Nat Genet (2003) 1.31
Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling. J Biol Chem (2008) 1.30
Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies. J Immunol (2007) 1.30
Serum levels of an isoform of apolipoprotein A-II as a potential marker for prostate cancer. Clin Cancer Res (2005) 1.30
Metastasis suppression by breast cancer metastasis suppressor 1 involves reduction of phosphoinositide signaling in MDA-MB-435 breast carcinoma cells. Cancer Res (2005) 1.30
Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435. Clin Exp Metastasis (2006) 1.30
Expression and functional role of CCR9 in prostate cancer cell migration and invasion. Clin Cancer Res (2004) 1.29
Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone. Oncol Rep (2009) 1.29
Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. Int J Radiat Oncol Biol Phys (2002) 1.28
Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer. Mol Cell Biol (2009) 1.28
Microarray analysis reveals potential mechanisms of BRMS1-mediated metastasis suppression. Clin Exp Metastasis (2007) 1.24
Bax expression is a candidate prognostic and predictive marker of colorectal cancer. J Gastrointest Oncol (2010) 1.24
Pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Gastroenterology (2008) 1.23
Breast cancer metastasis suppressor 1: update. Clin Exp Metastasis (2003) 1.23
A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis. Clin Exp Metastasis (2004) 1.23
Identification of metastasis-associated proteins through protein analysis of metastatic MDA-MB-435 and metastasis-suppressed BRMS1 transfected-MDA-MB-435 cells. Clin Exp Metastasis (2004) 1.22
Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma. Laryngoscope (2003) 1.22
Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors. Oncogene (2005) 1.21
A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases. Clin Cancer Res (2010) 1.21
The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat. Hepatology (2004) 1.21
Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody. Radiology (2008) 1.20
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT. Mol Cell Biol (2005) 1.19
TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth. Mol Cancer Ther (2007) 1.18