Published in Am J Respir Crit Care Med on September 17, 2010
Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways. J Biol Chem (2013) 1.13
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease. Life Sci (2011) 1.08
Sarcoidosis vs. Sarcoid-like reactions: The Two Sides of the same Coin? Wien Med Wochenschr (2014) 1.05
The role of the innate immune system in granulomatous disorders. Front Immunol (2013) 0.89
p38 Mitogen-Activated Protein Kinase in beryllium-induced dendritic cell activation. Hum Immunol (2014) 0.81
Interleukin-12 family cytokines and sarcoidosis. Front Pharmacol (2014) 0.77
Model Predicts That MKP1 and TAB1 Regulate p38α Nuclear Pulse and Its Basal Activity through Positive and Negative Feedback Loops in Response to IL-1. PLoS One (2016) 0.76
Development of a T7 Phage Display Library to Detect Sarcoidosis and Tuberculosis by a Panel of Novel Antigens. EBioMedicine (2015) 0.76
Concomitant pemphigus herpetiformis and sarcoidosis. JAAD Case Rep (2016) 0.75
Innate pathways shape sarcoidosis signaling: from bugs to drugs. Am J Respir Crit Care Med (2011) 0.75
New molecular targets for the treatment of sarcoidosis. Curr Opin Pulm Med (2016) 0.75
The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without Löfgren's Syndrome. Mediators Inflamm (2016) 0.75
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells. J Immunol (2016) 0.75
Metabolomics connects aberrant bioenergetic, transmethylation, and gut microbiota in sarcoidosis. Metabolomics (2016) 0.75
Lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, and sarcoidosis: more pathological findings in the same chest CT, or a single pathological pathway? BMC Pulm Med (2017) 0.75
The NLR gene family: a standard nomenclature. Immunity (2008) 4.77
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J Exp Med (2005) 3.37
Induction of Nod2 in myelomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation. J Biol Chem (2002) 3.27
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol (2007) 3.06
Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J Immunol (2002) 2.46
Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol (2012) 2.27
The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. J Biol Chem (2004) 2.22
The function of mitogen-activated protein kinase phosphatase-1 in peptidoglycan-stimulated macrophages. J Biol Chem (2004) 1.67
NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet (2005) 1.66
Regulation of innate immune response by MAP kinase phosphatase-1. Cell Signal (2007) 1.65
STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria. Mol Immunol (2009) 1.59
Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth. Cancer Res (2007) 1.53
Regulation of mitochondrial oxidative phosphorylation through cell signaling. Biochim Biophys Acta (2007) 1.51
The NOD2-RICK complex signals from the plasma membrane. J Biol Chem (2007) 1.50
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion (2011) 1.40
Knockout of Mkp-1 enhances the host inflammatory responses to gram-positive bacteria. J Immunol (2007) 1.40
Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res (2006) 1.35
Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines. Cancer Res (2005) 1.32
MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge. Am J Physiol Cell Physiol (2007) 1.28
Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice. J Immunol (2009) 1.27
Regulation of mitochondrial respiration and apoptosis through cell signaling: cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation. Biochim Biophys Acta (2011) 1.27
P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1. J Immunol (2009) 1.25
The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res (2006) 1.23
TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation. J Biol Chem (2011) 1.21
TLR4 is required for host resistance in Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2006) 1.20
TLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages. J Immunol (2012) 1.18
Feedback control of MKP-1 expression by p38. Cell Signal (2006) 1.18
Respiratory virus-induced TLR7 activation controls IL-17-associated increased mucus via IL-23 regulation. J Immunol (2010) 1.17
Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: a critical role of mitogen-activated protein kinase phosphatase 1. Endocrinology (2008) 1.16
Triptolide induces anti-inflammatory cellular responses. Am J Transl Res (2009) 1.15
Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways. J Biol Chem (2013) 1.13
SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling. J Immunol (2006) 1.13
Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. J Biol Chem (2003) 1.09
MAP kinase phosphatase-1, a critical negative regulator of the innate immune response. Int J Clin Exp Med (2009) 1.09
TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway. Oncogene (2002) 1.09
The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia. Life Sci (2008) 1.09
Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc. J Immunol (2004) 1.09
CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy. Arthritis Rheum (2002) 1.08
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease. Life Sci (2011) 1.08
NF-kappaB signaling in lymphocytes: a new cast of characters. J Cell Sci (2004) 1.07
Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Mol Cell Biol (2008) 1.07
Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor. Am J Respir Cell Mol Biol (2005) 1.06
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2007) 1.06
MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta. Proc Natl Acad Sci U S A (2008) 1.05
Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri. J Clin Invest (2007) 1.05
Fungicidal activity of fluconazole against Candida albicans in a synthetic vagina-simulative medium. Antimicrob Agents Chemother (2004) 1.03
Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation. J Clin Invest (2012) 1.03
Inducible nitric-oxide synthase expression is regulated by mitogen-activated protein kinase phosphatase-1. J Biol Chem (2009) 1.02
ERK and p38 MAPK signaling pathways negatively regulate CIITA gene expression in dendritic cells and macrophages. J Immunol (2006) 1.02
Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. J Biol Chem (2002) 1.00
Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes. Biochim Biophys Acta (2006) 0.98
NKT cells are critical to initiate an inflammatory response after Pseudomonas aeruginosa ocular infection in susceptible mice. J Immunol (2007) 0.97
Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinase-mediated apoptosis via NF-kappaB regulation. J Biol Chem (2008) 0.96
Gene transfer with inducible nitric oxide synthase decreases production of urea by arginase in pulmonary arterial endothelial cells. Am J Physiol Lung Cell Mol Physiol (2005) 0.96
A mammalian expression system for rapid production and purification of active MAP kinase phosphatases. Protein Expr Purif (2002) 0.96
Lack of mitogen-activated protein kinase phosphatase-1 protects ApoE-null mice against atherosclerosis. Circ Res (2010) 0.95
Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia. Am J Physiol Heart Circ Physiol (2010) 0.94
Embryonic loss due to exposure to polycyclic aromatic hydrocarbons is mediated by Bax. Apoptosis (2006) 0.93
Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps. J Immunol (2012) 0.93
Global expression of cell surface proteins in embryonic stem cells. PLoS One (2010) 0.92
Isolation of regulatory-competent, phosphorylated cytochrome C oxidase. Methods Enzymol (2009) 0.90
Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity. Free Radic Biol Med (2010) 0.89
Cytokine-induced arginase activity in pulmonary endothelial cells is dependent on Src family tyrosine kinase activity. Am J Physiol Lung Cell Mol Physiol (2008) 0.89
MAPK signaling drives inflammation in LPS-stimulated cardiomyocytes: the route of crosstalk to G-protein-coupled receptors. PLoS One (2012) 0.89
Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice. Inflamm Res (2011) 0.89
NOD2 deficiency results in increased susceptibility to peptidoglycan-induced uveitis in mice. Invest Ophthalmol Vis Sci (2011) 0.89
Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A. Proc Natl Acad Sci U S A (2010) 0.87
Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin. Am J Physiol Heart Circ Physiol (2008) 0.86
Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cells. Biochem Biophys Res Commun (2010) 0.86
Bioavailability of fondaparinux to critically ill patients. J Crit Care (2010) 0.86
Receptor-interacting protein shuttles between cell death and survival signaling pathways. Mol Biol Cell (2009) 0.85
Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide. J Mol Med (Berl) (2005) 0.85
Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library. Biochemistry (2006) 0.83
Can jurors recognize missing control groups, confounds, and experimenter bias in psychological science? Law Hum Behav (2008) 0.83
Mitogen-activated protein kinase phosphatase (Mkp)-1 protects mice against acetaminophen-induced hepatic injury. Toxicol Pathol (2012) 0.82
Intracellular thiols contribute to Th2 function via a positive role in IL-4 production. J Immunol (2003) 0.82
Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia. Cardiovasc Res (2011) 0.82
Influence of donor microbiota on the severity of experimental graft-versus-host-disease. Biol Blood Marrow Transplant (2012) 0.80
Aspergillus lung disease in patients with sarcoidosis: a case series and review of the literature. Lung (2011) 0.80
Redundant and cooperative interactions between TLR5 and NLRC4 in protective lung mucosal immunity against Pseudomonas aeruginosa. J Innate Immun (2014) 0.80
Knockout of Mkp-1 exacerbates colitis in Il-10-deficient mice. Am J Physiol Gastrointest Liver Physiol (2012) 0.79
Nitric oxide suppression of cellular proliferation depends on cationic amino acid transporter activity in cytokine-stimulated pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol (2011) 0.79
Production of active recombinant mitogen-activated protein kinases through transient transfection of 293T cells. Protein Expr Purif (2005) 0.78
Effect of smoking and gender on pulmonary function and clinical features in sarcoidosis. Lung (2012) 0.78
Nasal-associated lymphoid tissue is not an absolute requirement for the induction of rat tear IgA antibody responses. Curr Eye Res (2010) 0.77
Distance saturation product predicts health-related quality of life among sarcoidosis patients. Health Qual Life Outcomes (2012) 0.77
The carboxyl-terminal domains of MKP-1 and MKP-2 have inhibitory effects on their phosphatase activity. Mol Cell Biochem (2002) 0.77
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine. Am J Physiol Heart Circ Physiol (2012) 0.75
Role of Pulmonary Evaluation in Diagnosis of Neurosarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis (2016) 0.75