Published in J Biol Chem on October 17, 2002
An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ Health Perspect (2010) 2.16
Environmental chemical exposures and human epigenetics. Int J Epidemiol (2011) 1.97
From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia. Blood (2011) 1.41
Epigenetic effects of ethanol on liver and gastrointestinal injury. World J Gastroenterol (2006) 1.29
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. J Neurochem (2004) 1.25
Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia. J Exp Med (2013) 1.15
Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde. Eur J Pharmacol (2007) 1.04
Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. Chromosoma (2007) 0.99
Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh. Cancer Epidemiol Biomarkers Prev (2012) 0.99
Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic. PLoS One (2013) 0.98
Quantitative Mass Spectrometry Reveals Changes in Histone H2B Variants as Cells Undergo Inorganic Arsenic-Mediated Cellular Transformation. Mol Cell Proteomics (2016) 0.92
Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges. Front Genet (2014) 0.90
Histone H3 phosphorylation (Ser10, Ser28) and phosphoacetylation (K9S10) are differentially associated with gene expression in liver of rats treated in vivo with acute ethanol. J Pharmacol Exp Ther (2011) 0.88
Perspectives of differentiation therapies of acute myeloid leukemia: the search for the molecular basis of patients' variable responses to 1,25-dihydroxyvitamin d and vitamin d analogs. Front Oncol (2014) 0.81
Silencer of death domains controls cell death through tumour necrosis factor-receptor 1 and caspase-10 in acute lymphoblastic leukemia. PLoS One (2014) 0.78
Downregulation of caspase-10 predicting poor survival after resection of stage II colorectal cancer. Int J Colorectal Dis (2011) 0.78
E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro. Environ Health Perspect (2015) 0.77
Inhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis. J Biomed Sci (2017) 0.75
Influence of Arsenic on Global Levels of Histone Posttranslational Modifications: a Review of the Literature and Challenges in the Field. Curr Environ Health Rep (2016) 0.75
PML-RARA mutations confer varying arsenic trioxide resistance. Protein Cell (2016) 0.75
Realgar nanoparticles versus ATO arsenic compounds induce in vitro and in vivo activity against multiple myeloma. Br J Haematol (2017) 0.75
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (2004) 11.39
Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell (2007) 5.29
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 5.22
Identification of a target RNA motif for RNA-binding protein HuR. Proc Natl Acad Sci U S A (2004) 5.15
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J (2004) 4.45
HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci U S A (2003) 4.34
LincRNA-p21 suppresses target mRNA translation. Mol Cell (2012) 3.87
Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci U S A (2002) 3.71
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J Exp Med (2005) 3.37
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell (2010) 3.27
AGEMAP: a gene expression database for aging in mice. PLoS Genet (2007) 3.22
p16(INK4a) translation suppressed by miR-24. PLoS One (2008) 3.08
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A (2008) 2.76
Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene (2003) 2.69
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. J Biol Chem (2006) 2.67
miR-519 suppresses tumor growth by reducing HuR levels. Cell Cycle (2010) 2.63
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem (2008) 2.60
Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip Rev RNA (2010) 2.59
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet (2013) 2.59
Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature (2010) 2.46
Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J Immunol (2002) 2.46
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling. J Biol Chem (2003) 2.38
HuR: post-transcriptional paths to malignancy. RNA Biol (2005) 2.38
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J (2005) 2.33
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci U S A (2008) 2.29
Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol (2012) 2.27
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol (2008) 2.26
Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle (2007) 2.25
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs. Mol Cell Biol (2007) 2.24
The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. J Biol Chem (2004) 2.22
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol (2007) 2.20
Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability. BMC Genomics (2005) 2.18
Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev (2008) 2.14
AMP-activated kinase regulates cytoplasmic HuR. Mol Cell Biol (2002) 2.14
Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity (2009) 2.11
Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells. Cancer Res (2011) 2.11
GU-rich RNA: expanding CUGBP1 function, broadening mRNA turnover. Mol Cell (2008) 2.08
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol (2006) 2.05
Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability. Clin Cancer Res (2006) 2.02
Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron (2004) 1.99
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs. Sci Signal (2009) 1.97
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J Biol Chem (2003) 1.95
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol (2003) 1.93
microRNA expression patterns reveal differential expression of target genes with age. PLoS One (2010) 1.92
The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res (2009) 1.88
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Posttranscriptional gene regulation by long noncoding RNA. J Mol Biol (2012) 1.87
HuR function in disease. Front Biosci (Landmark Ed) (2012) 1.86
Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines. Nucleic Acids Res (2009) 1.86
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. Mol Cell Biol (2003) 1.83
SRT1720 improves survival and healthspan of obese mice. Sci Rep (2011) 1.81
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75
Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Pept Sci (2012) 1.71
Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs. J Biol Chem (2006) 1.69
The function of mitogen-activated protein kinase phosphatase-1 in peptidoglycan-stimulated macrophages. J Biol Chem (2004) 1.67
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Proc Natl Acad Sci U S A (2005) 1.67
Dysregulation of p38 and MKP-1 in response to NOD1/TLR4 stimulation in sarcoid bronchoalveolar cells. Am J Respir Crit Care Med (2010) 1.66
Regulation of innate immune response by MAP kinase phosphatase-1. Cell Signal (2007) 1.65
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination. Nat Commun (2013) 1.62
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat Struct Mol Biol (2010) 1.61
Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR. J Immunol (2003) 1.57
MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence. Aging (Albany NY) (2010) 1.53
Ubiquitin-mediated proteolysis of HuR by heat shock. EMBO J (2009) 1.52
Posttranscriptional derepression of GADD45alpha by genotoxic stress. Mol Cell (2006) 1.50
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif. Nucleic Acids Res (2009) 1.50
RNA-binding protein nucleolin in disease. RNA Biol (2012) 1.47
Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase. Mol Cell Biol (2003) 1.47
Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp Cell Res (2002) 1.47
Stability regulation of mRNA and the control of gene expression. Ann N Y Acad Sci (2005) 1.46
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nat Neurosci (2013) 1.46
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR. J Biol Chem (2004) 1.46
An in vitro model of caloric restriction. Exp Gerontol (2003) 1.46
Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. Mol Cell Biol (2007) 1.44
miR-375 inhibits differentiation of neurites by lowering HuD levels. Mol Cell Biol (2010) 1.43
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase. Cancer Res (2009) 1.41
Knockout of Mkp-1 enhances the host inflammatory responses to gram-positive bacteria. J Immunol (2007) 1.40
Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response. Mol Cell Biol (2004) 1.38
Phosphorylated HuR shuttles in cycles. Cell Cycle (2008) 1.38
Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation. Mol Biol Cell (2009) 1.38
Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes. Glia (2013) 1.37
von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays. Mol Cell Biol (2003) 1.37
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay. Mol Cell Biol (2010) 1.35
Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR. J Biol Chem (2004) 1.35
Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res (2006) 1.35
B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. PLoS One (2008) 1.32
Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress. Neuromolecular Med (2006) 1.28
MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge. Am J Physiol Cell Physiol (2007) 1.28
Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. Mol Biol Cell (2007) 1.28
Competitive regulation of nucleolin expression by HuR and miR-494. Mol Cell Biol (2011) 1.28
Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice. J Immunol (2009) 1.27
Variable levels of chromosomal instability and mitotic spindle checkpoint defects in breast cancer. Am J Pathol (2002) 1.26
Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response. Blood (2006) 1.26
miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies. Mol Biol Cell (2011) 1.26