Published in Anal Bioanal Chem on September 25, 2010
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Miniaturized bioaffinity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail. Biology (Basel) (2014) 0.75
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A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures. J Am Chem Soc (2004) 0.94
Integrated microfluidic immunoassay for the rapid determination of clenbuterol. Lab Chip (2009) 0.94
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Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS. Anal Bioanal Chem (2010) 0.87
Development of a countergradient parking system for gradient liquid chromatography with online biochemical detection of serine protease inhibitors. Anal Chem (2008) 0.87
A microfluidic-based enzymatic assay for bioactivity screening combined with capillary liquid chromatography and mass spectrometry. Lab Chip (2005) 0.86
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Strategies to improve the sensitivity in capillary electrophoresis for the analysis of drugs in biological fluids. Electrophoresis (2000) 0.86
Stopped-flow enzyme assays on a chip using a microfabricated mixer. Anal Chem (2003) 0.84
Reversed-phase liquid chromatography coupled on-line to receptor affinity detection based on the human estrogen receptor. Anal Chem (1996) 0.81
An on-line post-column detection system for the detection of reactive-oxygen-species-producing compounds and antioxidants in mixtures. Anal Bioanal Chem (2007) 0.79
Microfluidic sequential injection analysis in a short capillary. Anal Chem (2006) 0.79
Electrophoresis on a microfluidic chip for analysis of fluorescence-labeled human rhinovirus. Electrophoresis (2007) 0.79
Competitive MS binding assays for dopamine D2 receptors employing spiperone as a native marker. Chembiochem (2005) 0.78
Portable in situ fluorescence cytometry of microscale cell-based assays. Opt Lett (2005) 0.77
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Capillary electrophoresis laser-induced fluorescence for screening combinatorial peptide libraries in assays of botulinum neurotoxin A. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.77
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Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nat Struct Mol Biol (2005) 2.45
Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability. Am J Hum Genet (2010) 2.02
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking. Nat Neurosci (2008) 1.98
Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet (2009) 1.87
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Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors. J Biol Chem (2005) 1.74
Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex. Neuron (2007) 1.72
The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov (2005) 1.67
The Netherlands Twin Register biobank: a resource for genetic epidemiological studies. Twin Res Hum Genet (2010) 1.65
Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats. J Neurosci (2003) 1.61
Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of contextual fear. Nat Neurosci (2011) 1.60
Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology. J Biol Chem (2003) 1.56
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Neuroadaptive effects of active versus passive drug administration in addiction research. Trends Pharmacol Sci (2003) 1.47
Insight in nAChR subtype selectivity from AChBP crystal structures. Biochem Pharmacol (2009) 1.44
A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors. PLoS Biol (2011) 1.38
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Analytical separation and detection methods for flavonoids. J Chromatogr A (2006) 1.36
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The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease. Microbiology (2009) 1.34
Development of the motivational system during adolescence, and its sensitivity to disruption by nicotine. Dev Cogn Neurosci (2011) 1.33
Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury. Eur J Neurosci (2007) 1.33
Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry. Rapid Commun Mass Spectrom (2003) 1.31
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands. Nat Chem Biol (2012) 1.31
Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor. J Med Chem (2011) 1.30
A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Twin Res Hum Genet (2010) 1.30
Nicotinic acetylcholine receptor β2 subunits in the medial prefrontal cortex control attention. Science (2011) 1.28
Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacology (2008) 1.26
Prefrontal cortex plasticity mechanisms in drug seeking and relapse. Neurosci Biobehav Rev (2009) 1.23
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proc Natl Acad Sci U S A (2012) 1.22
CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation. Neuron (2013) 1.21
Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo. J Med Chem (2008) 1.20
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Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein. J Biol Chem (2010) 1.18
Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin. J Med Chem (2007) 1.18
Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. Neuropsychopharmacology (2010) 1.17
Organelle proteomics of rat synaptic proteins: correlation-profiling by isotope-coded affinity tagging in conjunction with liquid chromatography-tandem mass spectrometry to reveal post-synaptic density specific proteins. J Proteome Res (2005) 1.17
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Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence. Nat Neurosci (2011) 1.16
Inhibitory control and response latency differences between C57BL/6J and DBA/2J mice in a Go/No-Go and 5-choice serial reaction time task and strain-specific responsivity to amphetamine. Behav Brain Res (2010) 1.14
Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling. PLoS One (2013) 1.12
NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. J Neurosci (2009) 1.11
Towards small-molecule CXCR3 ligands with clinical potential. ChemMedChem (2008) 1.11
Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis. J Med Chem (2009) 1.11
Automated serum peptide profiling using novel magnetic C18 beads off-line coupled to MALDI-TOF-MS. Proteomics Clin Appl (2007) 1.10
Quantitative proteomics and protein network analysis of hippocampal synapses of CaMKIIalpha mutant mice. J Proteome Res (2007) 1.10
A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis. Steroids (2013) 1.09
Transforming fragments into candidates: small becomes big in medicinal chemistry. Drug Discov Today (2009) 1.09
Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype. J Biol Chem (2011) 1.09
Stimulated gene expression profiles as a blood marker of major depressive disorder. Biol Psychiatry (2010) 1.06
Molecular and biochemical pharmacology of the histamine H4 receptor. Br J Pharmacol (2009) 1.06
Ventromedial prefrontal cortex pyramidal cells have a temporal dynamic role in recall and extinction of cocaine-associated memory. J Neurosci (2013) 1.06
SCAP is required for timely and proper myelin membrane synthesis. Proc Natl Acad Sci U S A (2009) 1.05
Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein. Proc Natl Acad Sci U S A (2012) 1.04
Biosensor discovery of thyroxine transport disrupting chemicals. Toxicol Appl Pharmacol (2008) 1.04
Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation. Eur J Pharmacol (2007) 1.04
Local synthesis of actin-binding protein beta-thymosin regulates neurite outgrowth. J Neurosci (2006) 1.02
Enhanced cortical and accumbal molecular reactivity associated with conditioned heroin, but not sucrose-seeking behaviour. J Neurochem (2006) 1.02
CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist. Neuropharmacology (2007) 1.02
Dopamine receptor D1/D5 gene expression in the medial prefrontal cortex predicts impulsive choice in rats. Cereb Cortex (2009) 1.02
Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition. J Neurosci (2003) 1.00
Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis. J Am Chem Soc (2011) 1.00
Catechol pyrazolinones as trypanocidals: fragment-based design, synthesis, and pharmacological evaluation of nanomolar inhibitors of trypanosomal phosphodiesterase B1. J Med Chem (2012) 0.99
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis. Mol Cell Biol (2011) 0.99
The synaptic proteome during development and plasticity of the mouse visual cortex. Mol Cell Proteomics (2011) 0.99
Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors. J Pharmacol Exp Ther (2008) 0.99
SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations. Nucleic Acids Res (2012) 0.98
Protein digestion: an overview of the available techniques and recent developments. J Proteome Res (2013) 0.98
Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach. J Med Chem (2008) 0.98
Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein. J Biol Chem (2012) 0.98
Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure. Neuropsychopharmacology (2006) 0.96
Peptidomics of a single identified neuron reveals diversity of multiple neuropeptides with convergent actions on cellular excitability. J Neurosci (2006) 0.96
Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28. J Med Chem (2005) 0.96
Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic. Neuropharmacology (2006) 0.96
Structural basis of ligand recognition in 5-HT3 receptors. EMBO Rep (2012) 0.96
Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification. J Med Chem (2010) 0.96
Calcium channel structural determinants of synaptic transmission between identified invertebrate neurons. J Biol Chem (2002) 0.95
Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry. Phytochemistry (2004) 0.95
Identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc Lymnaea stagnalis. J Biol Chem (2005) 0.94
Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs. J Neurosci (2005) 0.94
A gene network perspective on axonal regeneration. Front Mol Neurosci (2011) 0.94
SREBP-1c expression in Schwann cells is affected by diabetes and nutritional status. Mol Cell Neurosci (2007) 0.94
Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor. J Neurochem (2009) 0.93
REM sleep behavior disorder in the marmoset MPTP model of early Parkinson disease. Sleep (2011) 0.93
Morphine exposure and abstinence define specific stages of gene expression in the rat nucleus accumbens. FASEB J (2004) 0.93
Molecular determinants of ligand binding to H4R species variants. Mol Pharmacol (2010) 0.93
Bioanalytical LC-MS/MS of protein-based biopharmaceuticals. J Chromatogr B Analyt Technol Biomed Life Sci (2013) 0.92
Active heroin administration induces specific genomic responses in the nucleus accumbens shell. FASEB J (2002) 0.92