Published in J Ocul Pharmacol Ther on October 01, 2010
Resolvins and protectins in inflammation resolution. Chem Rev (2011) 3.09
Dry eye disease: an immune-mediated ocular surface disorder. Arch Ophthalmol (2012) 2.23
Controlling herpes simplex virus-induced ocular inflammatory lesions with the lipid-derived mediator resolvin E1. J Immunol (2010) 1.38
Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution. Biochem J (2011) 1.23
Resolvin D1 prevents TNF-α-mediated disruption of salivary epithelial formation. Am J Physiol Cell Physiol (2012) 1.15
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders. Clin Interv Aging (2013) 1.12
Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation. Front Immunol (2012) 1.06
Lipid mediators in the resolution of inflammation. Cold Spring Harb Perspect Biol (2014) 1.04
Patients undergoing long-term treatment with antihypertensive eye drops responded positively with respect to their ocular surface disorder to oral supplementation with antioxidants and essential fatty acids. Clin Interv Aging (2013) 1.01
Neuropathic ocular pain: an important yet underevaluated feature of dry eye. Eye (Lond) (2014) 1.00
Resolvin D1 and aspirin-triggered resolvin D1 regulate histamine-stimulated conjunctival goblet cell secretion. Mucosal Immunol (2013) 1.00
Specialized pro-resolving mediators: endogenous regulators of infection and inflammation. Nat Rev Immunol (2015) 0.99
Dry eye disease: A review of diagnostic approaches and treatments. Saudi J Ophthalmol (2014) 0.98
Natural resolution of inflammation. Periodontol 2000 (2013) 0.97
Dry eye: an inflammatory ocular disease. J Ophthalmic Vis Res (2014) 0.95
ALX/FPR2 receptor for RvD1 is expressed and functional in salivary glands. Am J Physiol Cell Physiol (2013) 0.92
Selenium compound protects corneal epithelium against oxidative stress. PLoS One (2012) 0.92
Docosahexaenoic acid, protectins and dry eye. Curr Opin Clin Nutr Metab Care (2011) 0.90
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model. BMB Rep (2013) 0.86
Expression of resolvin D1 biosynthetic pathways in salivary epithelium. J Dent Res (2014) 0.86
Involvement of pigment epithelium-derived factor, docosahexaenoic acid and neuroprotectin D1 in corneal inflammation and nerve integrity after refractive surgery. Prostaglandins Leukot Essent Fatty Acids (2012) 0.83
Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms. FASEB J (2017) 0.83
Interaction Studies of Resolvin E1 Analog (RX-10045) with Efflux Transporters. J Ocul Pharmacol Ther (2015) 0.82
Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK. Mol Vis (2014) 0.82
Topical delivery of aqueous micellar resolvin E1 analog (RX-10045). Int J Pharm (2015) 0.77
Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology. Mol Aspects Med (2017) 0.77
Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors. Mol Aspects Med (2017) 0.76
ω-3 Tear Film Lipids Correlate With Clinical Measures of Dry Eye. Invest Ophthalmol Vis Sci (2016) 0.76
Resolvins and aliamides: lipid autacoids in ophthalmology - what promise do they hold? Drug Des Devel Ther (2016) 0.76
Evaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model. Mol Vis (2016) 0.75
A semifluorinated alkane (F4H5) as novel carrier for cyclosporine A: a promising therapeutic and prophylactic option for topical treatment of dry eye. Graefes Arch Clin Exp Ophthalmol (2017) 0.75
The role of pro-resolving lipid mediators in ocular diseases. Mol Aspects Med (2017) 0.75
Polyunsaturated fatty acids induce modification in the lipid composition and the prostaglandin production of the conjunctival epithelium cells. Graefes Arch Clin Exp Ophthalmol (2011) 0.75
Recovery of Corneal Sensitivity and Increase in Nerve Density and Wound Healing in Diabetic Mice After PEDF Plus DHA Treatment. Diabetes (2017) 0.75
The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf (2007) 5.62
The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother (2002) 5.58
Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis. Nat Med (2007) 4.36
Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress. Proc Natl Acad Sci U S A (2004) 4.28
Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Invest Ophthalmol Vis Sci (2001) 3.72
A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest (2005) 3.44
Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. Proc Natl Acad Sci U S A (2005) 3.32
Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci (2004) 3.22
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nat Immunol (2008) 3.15
The pathology of dry eye: the interaction between the ocular surface and lacrimal glands. Cornea (1998) 2.86
A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense. J Biol Chem (2005) 2.76
Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. Br J Pharmacol (2007) 2.67
Desiccating stress induces T cell-mediated Sjögren's Syndrome-like lacrimal keratoconjunctivitis. J Immunol (2006) 2.33
Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr (2005) 1.57
Alterations in corneal stromal dendritic cell phenotype and distribution in inflammation. Arch Ophthalmol (2003) 1.43
Epidemiology of dry eye syndrome. Adv Exp Med Biol (2002) 1.43
Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators. Invest Ophthalmol Vis Sci (2009) 1.42
Strain-related cytokine profiles on the murine ocular surface in response to desiccating stress. Cornea (2007) 1.31
Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia. Invest Ophthalmol Vis Sci (2003) 1.28
Evaluation of topical cyclosporine for the treatment of dry eye disease. Arch Ophthalmol (2008) 1.21
Resolvin E1 protects the rat heart against reperfusion injury. Am J Physiol Heart Circ Physiol (2010) 1.20
Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA. Invest Ophthalmol Vis Sci (2009) 1.20
The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem Biophys Res Commun (2005) 1.09
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells. Exp Eye Res (2010) 1.07
Chemokine receptor CCR5 expression in conjunctival epithelium of patients with dry eye syndrome. Arch Ophthalmol (2006) 1.04
Bone marrow-derived dendritic cells generated in the presence of resolvin E1 induce apoptosis of activated CD4+ T cells. J Immunol (2008) 1.01
High-frequency topical cyclosporine 0.05% in the treatment of severe dry eye refractory to twice-daily regimen. Cornea (2009) 0.98
Role of immunity and inflammation in corneal and ocular surface disease associated with dry eye. Adv Exp Med Biol (2002) 0.97
Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Graefes Arch Clin Exp Ophthalmol (2009) 0.96
Corneal stimulation of MMP-1, -9 and uPA by platelet-activating factor is mediated by cyclooxygenase-2 metabolites. Curr Eye Res (2001) 0.94
Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway. Invest Ophthalmol Vis Sci (1997) 0.93
Comparative in vivo high-resolution confocal microscopy of corneal epithelium, sub-basal nerves and stromal cells in mice with and without dry eye after photorefractive keratectomy. Clin Experiment Ophthalmol (2007) 0.92
The pharmacokinetics of a new antiglaucoma drug, latanoprost, in the rabbit. Drug Metab Dispos (1998) 0.89
Platelet-activating factor overturns the transcriptional repressor disposition of Sp1 in the expression of MMP-9 in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2007) 0.88
Inflammation-induced stimulation of the synthesis of prostaglandins and lipoxygenase-reaction products in rabbit cornea. Curr Eye Res (1985) 0.87
Corneal injury alters eicosanoid formation in the rabbit anterior segment in vivo. Invest Ophthalmol Vis Sci (1987) 0.83
A novel platelet activating factor receptor antagonist reduces cell infiltration and expression of inflammatory mediators in mice exposed to desiccating conditions after PRK. Clin Dev Immunol (2009) 0.80
PAF antagonists as possible inhibitors of corneal epithelial defects and ulceration. J Ocul Pharmacol Ther (1997) 0.78
p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades. J Biol Chem (2003) 1.99
Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation. Proc Natl Acad Sci U S A (2012) 1.49
Controlling herpes simplex virus-induced ocular inflammatory lesions with the lipid-derived mediator resolvin E1. J Immunol (2010) 1.38
Mapping the entire human corneal nerve architecture. Exp Eye Res (2010) 1.31
Topical combination of NGF and DHA increases rabbit corneal nerve regeneration after photorefractive keratectomy. Invest Ophthalmol Vis Sci (2005) 1.30
Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA. Invest Ophthalmol Vis Sci (2009) 1.20
Report of the TFOS/ARVO Symposium on global treatments for dry eye disease: an unmet need. Ocul Surf (2012) 1.19
Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. Mol Vis (2004) 1.09
Significance of lipid mediators in corneal injury and repair. J Lipid Res (2009) 1.08
Omega-3 fatty acids in dry eye and corneal nerve regeneration after refractive surgery. Prostaglandins Leukot Essent Fatty Acids (2010) 1.07
Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis (2010) 1.06
Epidermal growth factor synergism with TGF-beta1 via PI-3 kinase activity in corneal keratocyte differentiation. Invest Ophthalmol Vis Sci (2008) 1.05
HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway. Invest Ophthalmol Vis Sci (2004) 1.04
Mapping the nerve architecture of diabetic human corneas. Ophthalmology (2012) 1.02
Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery. Invest Ophthalmol Vis Sci (2013) 0.99
Recovery of corneal sensitivity, calcitonin gene-related peptide-positive nerves, and increased wound healing induced by pigment epithelial-derived factor plus docosahexaenoic acid after experimental surgery. Arch Ophthalmol (2011) 0.98
Dependence of resolvin-induced increases in corneal epithelial cell migration on EGF receptor transactivation. Invest Ophthalmol Vis Sci (2010) 0.98
Alkali-induced corneal stromal melting prevention by a novel platelet-activating factor receptor antagonist. Arch Ophthalmol (2006) 0.97
Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Calpha translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis. J Biol Chem (2004) 0.96
Synergistic effect of platelet-activating factor and tumor necrosis factor-alpha on corneal myofibroblast apoptosis. Invest Ophthalmol Vis Sci (2006) 0.94
EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation. Invest Ophthalmol Vis Sci (2011) 0.94
Delay of corneal epithelial wound healing and induction of keratocyte apoptosis by platelet-activating factor. Invest Ophthalmol Vis Sci (2002) 0.93
Comparative in vivo high-resolution confocal microscopy of corneal epithelium, sub-basal nerves and stromal cells in mice with and without dry eye after photorefractive keratectomy. Clin Experiment Ophthalmol (2007) 0.92
Association of protein tyrosine phosphatases (PTPs)-1B with c-Met receptor and modulation of corneal epithelial wound healing. Invest Ophthalmol Vis Sci (2008) 0.91
The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis. Epilepsia (2011) 0.90
Docosahexaenoic acid, protectins and dry eye. Curr Opin Clin Nutr Metab Care (2011) 0.90
Wound-healing response and refractive regression after conductive keratoplasty. J Cataract Refract Surg (2006) 0.90
Platelet-activating factor (PAF) induces activation of matrix metalloproteinase 2 activity and vascular endothelial cell invasion and migration. FASEB J (2004) 0.90
Platelet-activating factor (PAF) induces corneal neovascularization and upregulates VEGF expression in endothelial cells. Invest Ophthalmol Vis Sci (2004) 0.89
Platelet-activating factor induces the gene expression of TIMP-1, -2, and PAI-1: imbalance between the gene expression of MMP-9 and TIMP-1 and -2. Exp Eye Res (2002) 0.88
Platelet-activating factor overturns the transcriptional repressor disposition of Sp1 in the expression of MMP-9 in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2007) 0.88
Healing process at the flap edge in its influence in the development of corneal ectasia after LASIK. Curr Eye Res (2006) 0.87
Prevention of experimental diffuse lamellar keratitis using a novel platelet-activating factor receptor antagonist. J Cataract Refract Surg (2004) 0.87
Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria. J Neurosci Res (2002) 0.86
Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology. Invest Ophthalmol Vis Sci (2013) 0.86
Comparison of corneal wound-healing response in photorefractive keratectomy and laser-assisted subepithelial keratectomy. J Cataract Refract Surg (2005) 0.85
Protein kinase C alpha and epsilon differentially modulate hepatocyte growth factor-induced epithelial proliferation and migration. Exp Eye Res (2007) 0.83
Growth factor-induced proliferation in corneal epithelial cells is mediated by 12(S)-HETE. Exp Eye Res (2003) 0.83
PAF-induced furin and MT1-MMP expression is independent of MMP-2 activation in corneal myofibroblasts. Invest Ophthalmol Vis Sci (2005) 0.82
Corneal nerve architecture in a donor with unilateral epithelial basement membrane dystrophy. Ophthalmic Res (2013) 0.81
Corneal keloid in Lowe syndrome. J Pediatr Ophthalmol Strabismus (2005) 0.81
Regulation of Cdc42 expression and signaling is critical for promoting corneal epithelial wound healing. Invest Ophthalmol Vis Sci (2013) 0.81
A novel platelet activating factor receptor antagonist reduces cell infiltration and expression of inflammatory mediators in mice exposed to desiccating conditions after PRK. Clin Dev Immunol (2009) 0.80
Aspirin-triggered lipoxin A4 (15-epi-LXA4) increases the endothelial viability of human corneas storage in Optisol-GS. J Ocul Pharmacol Ther (2011) 0.80
Use of autologous serum in corneal epithelial defects post-lamellar surgery. Cornea (2005) 0.79
Role of platelet-activating factor in cell death signaling in the cornea: A review. Mol Neurobiol (2010) 0.77
Lipoxin A₄ inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma. Exp Eye Res (2012) 0.77
The induction of an angiogenic response in corneal myofibroblasts by platelet-activating factor (PAF). Curr Eye Res (2010) 0.76
Immunofluorescence of rabbit corneas after collagen cross-linking treatment with riboflavin and ultraviolet A. Cornea (2010) 0.75
Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye. Res Sq (2020) 0.75