Published in Endocrinology on September 29, 2010
A maternal high-fat, high-sucrose diet has sex-specific effects on fetal glucocorticoids with little consequence for offspring metabolism and voluntary locomotor activity in mice. PLoS One (2017) 0.75
Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice. PLoS One (2017) 0.75
Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. J Clin Endocrinol Metab (2004) 3.54
Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons. Cell Metab (2007) 3.43
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat Biotechnol (2004) 3.36
Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation. Am J Hum Genet (2006) 3.29
Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice. Diabetes (2012) 2.40
Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Cell Metab (2012) 2.04
Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes (2012) 1.91
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88
Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice. Cardiovasc Res (2012) 1.77
Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis. Endocrinology (2007) 1.77
Production of functional glucagon-secreting α-cells from human embryonic stem cells. Diabetes (2010) 1.73
The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis. Cell Metab (2006) 1.70
Modeling and inferring cleavage patterns in proliferating epithelia. PLoS Comput Biol (2009) 1.52
Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. Am J Physiol Endocrinol Metab (2008) 1.50
Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells (2013) 1.47
Development of metabolic systems. Physiol Behav (2005) 1.43
Targeting the glucagon receptor family for diabetes and obesity therapy. Pharmacol Ther (2012) 1.39
Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents. J Clin Endocrinol Metab (2005) 1.38
Schinzel-Giedion syndrome: report of splenopancreatic fusion and proposed diagnostic criteria. Am J Med Genet A (2008) 1.29
Novel deletions of 14q11.2 associated with developmental delay, cognitive impairment and similar minor anomalies in three children. J Med Genet (2007) 1.28
Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene. J Clin Invest (2007) 1.26
Body weight is modulated by levels of full-length huntingtin. Hum Mol Genet (2006) 1.25
Decreasing linoleic acid with constant alpha-linolenic acid in dietary fats increases (n-3) eicosapentaenoic acid in plasma phospholipids in healthy men. J Nutr (2007) 1.21
Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion. Gastroenterology (2010) 1.20
Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia. J Biol Chem (2007) 1.18
Circulating miR-375 as a biomarker of β-cell death and diabetes in mice. Endocrinology (2013) 1.14
Duodenal-jejunal bypass protects GK rats from {beta}-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1. Am J Physiol Endocrinol Metab (2011) 1.12
Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain. J Nutr (2006) 1.11
Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets. J Clin Invest (2011) 1.10
Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling. Diabetes (2011) 1.10
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. J Lipid Res (2007) 1.09
Pleiotropic effects of GIP on islet function involve osteopontin. Diabetes (2011) 1.08
Trans fatty acids in human milk in Canada declined with the introduction of trans fat food labeling. J Nutr (2006) 1.06
Phthalate metabolites in urine of CF patients are associated with use of enteric-coated pancreatic enzymes. Environ Toxicol Pharmacol (2009) 1.06
Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. Am J Clin Nutr (2009) 1.04
Glucagon-like peptide-1: glucose homeostasis and beyond. Annu Rev Physiol (2013) 1.03
Inhibition of preproinsulin gene expression by leptin induction of suppressor of cytokine signaling 3 in pancreatic beta-cells. Diabetes (2005) 1.03
A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice. Diabetes (2007) 1.02
Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1). Proc Natl Acad Sci U S A (2006) 1.02
A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control. PLoS One (2010) 1.02
Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS One (2012) 1.00
Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice. Diabetologia (2013) 0.99
Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology. Diabetes (2012) 0.99
High dietary omega-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth. Brain Res (2008) 0.99
Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation. J Neurosci (2005) 0.99
Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants. J Nutr (2007) 0.95
Pax6 and Pdx1 are required for production of glucose-dependent insulinotropic polypeptide in proglucagon-expressing L cells. Am J Physiol Endocrinol Metab (2008) 0.95
Controversial nutrients that potentially affect preterm neurodevelopment: essential fatty acids and iron. Pediatr Res (2005) 0.94
Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization. BMC Genomics (2009) 0.94
Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary omega-6 polyunsaturated fatty acids. Free Radic Biol Med (2006) 0.94
Leptin increases hepatic insulin sensitivity and protein tyrosine phosphatase 1B expression. Mol Endocrinol (2004) 0.93
Differential processing of pro-glucose-dependent insulinotropic polypeptide in gut. Am J Physiol Gastrointest Liver Physiol (2010) 0.93
K-cells and glucose-dependent insulinotropic polypeptide in health and disease. Vitam Horm (2010) 0.93
Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells. PLoS One (2013) 0.92
Disruption of hepatic leptin signaling protects mice from age- and diet-related glucose intolerance. Diabetes (2010) 0.92
Link between GIP and osteopontin in adipose tissue and insulin resistance. Diabetes (2013) 0.92
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine. Am J Clin Nutr (2005) 0.92
Low fish intake is associated with low blood concentrations of vitamin D, choline and n-3 DHA in pregnant women. Br J Nutr (2012) 0.91
Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling. Endocrinology (2010) 0.90
Acute disruption of leptin signaling in vivo leads to increased insulin levels and insulin resistance. Endocrinology (2011) 0.90
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently. Rev Diabet Stud (2004) 0.90
Leptin extends the anorectic effects of chronic PYY(3-36) administration in ad libitum-fed rats. Am J Physiol Regul Integr Comp Physiol (2008) 0.90
A role for hepatic leptin signaling in lipid metabolism via altered very low density lipoprotein composition and liver lipase activity in mice. Hepatology (2012) 0.89
Cardiac proinflammatory pathways are altered with different dietary n-6 linoleic to n-3 alpha-linolenic acid ratios in normal, fat-fed pigs. Am J Physiol Heart Circ Physiol (2007) 0.89
Dietary oils modify the host immune response and colonic tissue damage following Citrobacter rodentium infection in mice. Am J Physiol Gastrointest Liver Physiol (2013) 0.88
Mining incretin hormone pathways for novel therapies. Trends Endocrinol Metab (2009) 0.88
AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes. J Mol Cell Cardiol (2006) 0.88
In vivo expression of HGF/NK1 and GLP-1 From dsAAV vectors enhances pancreatic ß-cell proliferation and improves pathology in the db/db mouse model of diabetes. Diabetes (2010) 0.88
Predictors and outcomes of household food insecurity among inner city families with preschool children in Vancouver. Can J Public Health (2006) 0.86
Suboptimal vitamin D levels in pregnant women despite supplement use. Can J Public Health (2011) 0.86
Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure. Neurosci Lett (2013) 0.86
Bakery foods are the major dietary source of trans-fatty acids among pregnant women with diets providing 30 percent energy from fat. J Am Diet Assoc (2002) 0.86
Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death. Nutrition (2004) 0.86
Cleavage of protein kinase D after acute hypoinsulinemia prevents excessive lipoprotein lipase-mediated cardiac triglyceride accumulation. Diabetes (2009) 0.85
Postnatal handling does not normalize hypothalamic corticotropin-releasing factor mRNA levels in animals prenatally exposed to ethanol. Brain Res Dev Brain Res (2005) 0.85
Left ventricular mechanics and arterial-ventricular coupling following high-intensity interval exercise. J Appl Physiol (1985) (2013) 0.85
Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men. Prostaglandins Leukot Essent Fatty Acids (2009) 0.84
Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques. J Endocrinol (2013) 0.84
Impact of maternal dietary n-3 and n-6 fatty acids on milk medium-chain fatty acids and the implications for neonatal liver metabolism. Am J Physiol Endocrinol Metab (2011) 0.84
Food frequency questionnaire for assessing infant iron nutrition. Can J Diet Pract Res (2005) 0.84
Intestinal responsiveness to experimental colitis in young rats is altered by maternal diet. Am J Physiol Gastrointest Liver Physiol (2005) 0.83
Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study. J Nutrigenet Nutrigenomics (2010) 0.83
Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology (2014) 0.83
A human embryonic stem cell line adapted for high throughput screening. Biotechnol Bioeng (2013) 0.83
Clinical study of two brothers with a novel 33 bp duplication in the ARX gene. Am J Med Genet A (2009) 0.83
Metabolic development in the liver and the implications of the n-3 fatty acid supply. Am J Physiol Gastrointest Liver Physiol (2011) 0.83
Hypaphorine is present in human milk in association with consumption of legumes. J Agric Food Chem (2013) 0.82
Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA. Am J Physiol Heart Circ Physiol (2004) 0.82
Metabolic effects of chronic obestatin infusion in rats. Peptides (2008) 0.82
beta-Agonist stimulation produces changes in cardiac AMPK and coronary lumen LPL only during increased workload. Am J Physiol Endocrinol Metab (2005) 0.82
Pseudohypoparathyroidism type 1a and the GNAS p.R231H mutation: Somatic mosaicism in a mother with two affected sons. Am J Med Genet A (2010) 0.82
Cellular reprogramming of human amniotic fluid cells to express insulin. Differentiation (2010) 0.81
Sources of trans and saturated fatty acids in the diets of Vancouver children. Can J Diet Pract Res (2013) 0.81
Phospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults. Lipids Health Dis (2014) 0.81
Transplantation of PC1/3-Expressing alpha-cells improves glucose handling and cold tolerance in leptin-resistant mice. Mol Ther (2008) 0.81
Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice. Am J Physiol Endocrinol Metab (2012) 0.81
Involvement of adenosine signaling in controlling the release of ghrelin from the mouse stomach. J Pharmacol Exp Ther (2010) 0.81