|
1
|
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
|
Nature
|
2012
|
10.99
|
|
2
|
Medulloblastoma comprises four distinct molecular variants.
|
J Clin Oncol
|
2010
|
8.06
|
|
3
|
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
|
Cancer Cell
|
2012
|
6.71
|
|
4
|
FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma.
|
J Clin Oncol
|
2011
|
3.33
|
|
5
|
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.
|
Cancer Cell
|
2011
|
3.11
|
|
6
|
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.
|
Cell
|
2013
|
2.74
|
|
7
|
Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p.
|
Blood
|
2011
|
2.37
|
|
8
|
Molecular staging of intracranial ependymoma in children and adults.
|
J Clin Oncol
|
2010
|
2.27
|
|
9
|
Adult medulloblastoma comprises three major molecular variants.
|
J Clin Oncol
|
2011
|
2.07
|
|
10
|
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.
|
Acta Neuropathol
|
2011
|
2.01
|
|
11
|
Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load.
|
J Clin Oncol
|
2013
|
1.84
|
|
12
|
Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.
|
Acta Neuropathol
|
2010
|
1.82
|
|
13
|
Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma.
|
Haematologica
|
2010
|
1.73
|
|
14
|
Prognostic significance of focal lesions in whole-body magnetic resonance imaging in patients with asymptomatic multiple myeloma.
|
J Clin Oncol
|
2010
|
1.60
|
|
15
|
Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation.
|
Haematologica
|
2010
|
1.58
|
|
16
|
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
|
Acta Neuropathol
|
2012
|
1.33
|
|
17
|
Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.
|
Acta Neuropathol
|
2011
|
1.32
|
|
18
|
mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.
|
Proc Natl Acad Sci U S A
|
2013
|
1.20
|
|
19
|
Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma.
|
Blood
|
2009
|
1.16
|
|
20
|
High-dimensional Cox models: the choice of penalty as part of the model building process.
|
Biom J
|
2010
|
1.15
|
|
21
|
Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.
|
Cancer Res
|
2010
|
1.07
|
|
22
|
A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR.
|
Epigenetics
|
2012
|
1.05
|
|
23
|
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
|
Acta Neuropathol
|
2011
|
1.04
|
|
24
|
Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma.
|
Haematologica
|
2012
|
1.04
|
|
25
|
HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas.
|
J Clin Invest
|
2013
|
1.01
|
|
26
|
Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.
|
Carcinogenesis
|
2011
|
0.99
|
|
27
|
MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.
|
Acta Neuropathol
|
2011
|
0.96
|
|
28
|
Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective.
|
Neuro Oncol
|
2013
|
0.95
|
|
29
|
Chromosomal aberrations +1q21 and del(17p13) predict survival in patients with recurrent multiple myeloma treated with lenalidomide and dexamethasone.
|
Cancer
|
2010
|
0.94
|
|
30
|
Nestin expression identifies ependymoma patients with poor outcome.
|
Brain Pathol
|
2012
|
0.92
|
|
31
|
The insulin-like growth factor binding proteins 3 and 7 are associated with colorectal cancer and liver metastasis.
|
Cancer Biol Ther
|
2011
|
0.92
|
|
32
|
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
|
Acta Neuropathol Commun
|
2015
|
0.91
|
|
33
|
Gene expression profiling in multiple myeloma--reporting of entities, risk, and targets in clinical routine.
|
Clin Cancer Res
|
2011
|
0.91
|
|
34
|
Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib. Laboratory investigation.
|
J Neurosurg
|
2009
|
0.89
|
|
35
|
Lenalidomide in combination with dexamethasone: effective regimen in patients with relapsed or refractory multiple myeloma complicated by renal impairment.
|
Ann Hematol
|
2010
|
0.88
|
|
36
|
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging of bone marrow in healthy individuals.
|
Acta Radiol
|
2011
|
0.87
|
|
37
|
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
|
Cancer Res
|
2014
|
0.87
|
|
38
|
Fibroblast growth factor receptor 4 gene (FGFR4) 388Arg allele predicts prolonged survival and platinum sensitivity in advanced ovarian cancer.
|
Int J Cancer
|
2012
|
0.85
|
|
39
|
Somatostatin receptor subtype 2 (sst₂) is a potential prognostic marker and a therapeutic target in medulloblastoma.
|
Childs Nerv Syst
|
2013
|
0.85
|
|
40
|
Comparison of peripheral zone and central gland volume in patients undergoing intensity-modulated radiotherapy.
|
J Comput Assist Tomogr
|
2010
|
0.84
|
|
41
|
Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia.
|
PLoS One
|
2013
|
0.83
|
|
42
|
Pathogenetic pathways leading to glioblastoma multiforme: association between gene expressions and resistance to erlotinib.
|
Anticancer Res
|
2009
|
0.82
|
|
43
|
Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib.
|
Anticancer Res
|
2009
|
0.80
|
|
44
|
Sequential biphasic changes in claudin1 and claudin4 expression are correlated to colorectal cancer progression and liver metastasis.
|
J Cell Mol Med
|
2012
|
0.79
|
|
45
|
A robust alternative to the schemper-henderson estimator of prediction error.
|
Biometrics
|
2010
|
0.79
|
|
46
|
Clinical outcome of patients with follicular lymphoma and bulky disease after rituximab-CHOP immunochemotherapy with and without consolidating radiotherapy.
|
Eur J Haematol
|
2010
|
0.78
|
|
47
|
NPM1 is overexpressed in hyperdiploid multiple myeloma due to a gain of chromosome 5 but is not delocalized to the cytoplasm.
|
Genes Chromosomes Cancer
|
2010
|
0.78
|
|
48
|
Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis.
|
Int J Cancer
|
2013
|
0.78
|
|
49
|
Epigenetic Silencing of DKK3 in medulloblastoma.
|
Int J Mol Sci
|
2013
|
0.77
|
|
50
|
Appearance of monoclonal plasma cell diseases in whole-body magnetic resonance imaging and correlation with parameters of disease activity.
|
Int J Cancer
|
2014
|
0.77
|
|
51
|
Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative.
|
Digestion
|
2016
|
0.76
|
|
52
|
Risk Factors for Local Recurrence of Large, Flat Colorectal Polyps after Endoscopic Mucosal Resection.
|
Digestion
|
2016
|
0.75
|
|
53
|
Metastasis-related processes show various degrees of activation in different stages of pancreatic cancer rat liver metastasis.
|
Oncol Res Treat
|
2014
|
0.75
|