PubRank

Thomas Hielscher

Author PubWeight™ 80.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012 10.99
2 Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 2010 8.06
3 Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012 6.71
4 FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol 2011 3.33
5 Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 2011 3.11
6 The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation. Cell 2013 2.74
7 Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p. Blood 2011 2.37
8 Molecular staging of intracranial ependymoma in children and adults. J Clin Oncol 2010 2.27
9 Adult medulloblastoma comprises three major molecular variants. J Clin Oncol 2011 2.07
10 Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol 2011 2.01
11 Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load. J Clin Oncol 2013 1.84
12 Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes. Acta Neuropathol 2010 1.82
13 Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma. Haematologica 2010 1.73
14 Prognostic significance of focal lesions in whole-body magnetic resonance imaging in patients with asymptomatic multiple myeloma. J Clin Oncol 2010 1.60
15 Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation. Haematologica 2010 1.58
16 Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathol 2012 1.33
17 Biological and clinical heterogeneity of MYCN-amplified medulloblastoma. Acta Neuropathol 2011 1.32
18 mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A 2013 1.20
19 Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma. Blood 2009 1.16
20 High-dimensional Cox models: the choice of penalty as part of the model building process. Biom J 2010 1.15
21 Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. Cancer Res 2010 1.07
22 A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR. Epigenetics 2012 1.05
23 A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat. Acta Neuropathol 2011 1.04
24 Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma. Haematologica 2012 1.04
25 HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. J Clin Invest 2013 1.01
26 Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma. Carcinogenesis 2011 0.99
27 MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. Acta Neuropathol 2011 0.96
28 Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective. Neuro Oncol 2013 0.95
29 Chromosomal aberrations +1q21 and del(17p13) predict survival in patients with recurrent multiple myeloma treated with lenalidomide and dexamethasone. Cancer 2010 0.94
30 Nestin expression identifies ependymoma patients with poor outcome. Brain Pathol 2012 0.92
31 The insulin-like growth factor binding proteins 3 and 7 are associated with colorectal cancer and liver metastasis. Cancer Biol Ther 2011 0.92
32 Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun 2015 0.91
33 Gene expression profiling in multiple myeloma--reporting of entities, risk, and targets in clinical routine. Clin Cancer Res 2011 0.91
34 Candidate genes for sensitivity and resistance of human glioblastoma multiforme cell lines to erlotinib. Laboratory investigation. J Neurosurg 2009 0.89
35 Lenalidomide in combination with dexamethasone: effective regimen in patients with relapsed or refractory multiple myeloma complicated by renal impairment. Ann Hematol 2010 0.88
36 Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging of bone marrow in healthy individuals. Acta Radiol 2011 0.87
37 GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3. Cancer Res 2014 0.87
38 Fibroblast growth factor receptor 4 gene (FGFR4) 388Arg allele predicts prolonged survival and platinum sensitivity in advanced ovarian cancer. Int J Cancer 2012 0.85
39 Somatostatin receptor subtype 2 (sst₂) is a potential prognostic marker and a therapeutic target in medulloblastoma. Childs Nerv Syst 2013 0.85
40 Comparison of peripheral zone and central gland volume in patients undergoing intensity-modulated radiotherapy. J Comput Assist Tomogr 2010 0.84
41 Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia. PLoS One 2013 0.83
42 Pathogenetic pathways leading to glioblastoma multiforme: association between gene expressions and resistance to erlotinib. Anticancer Res 2009 0.82
43 Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib. Anticancer Res 2009 0.80
44 Sequential biphasic changes in claudin1 and claudin4 expression are correlated to colorectal cancer progression and liver metastasis. J Cell Mol Med 2012 0.79
45 A robust alternative to the schemper-henderson estimator of prediction error. Biometrics 2010 0.79
46 Clinical outcome of patients with follicular lymphoma and bulky disease after rituximab-CHOP immunochemotherapy with and without consolidating radiotherapy. Eur J Haematol 2010 0.78
47 NPM1 is overexpressed in hyperdiploid multiple myeloma due to a gain of chromosome 5 but is not delocalized to the cytoplasm. Genes Chromosomes Cancer 2010 0.78
48 Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis. Int J Cancer 2013 0.78
49 Epigenetic Silencing of DKK3 in medulloblastoma. Int J Mol Sci 2013 0.77
50 Appearance of monoclonal plasma cell diseases in whole-body magnetic resonance imaging and correlation with parameters of disease activity. Int J Cancer 2014 0.77
51 Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative. Digestion 2016 0.76
52 Risk Factors for Local Recurrence of Large, Flat Colorectal Polyps after Endoscopic Mucosal Resection. Digestion 2016 0.75
53 Metastasis-related processes show various degrees of activation in different stages of pancreatic cancer rat liver metastasis. Oncol Res Treat 2014 0.75