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1
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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration.
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Proc Natl Acad Sci U S A
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2005
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13.44
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2
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The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
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Cell
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2003
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12.50
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3
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Retracted
Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.
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Science
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2009
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10.76
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4
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The genome of the sea urchin Strongylocentrotus purpuratus.
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Science
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2006
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6.41
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5
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Network modeling links breast cancer susceptibility and centrosome dysfunction.
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Nat Genet
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2007
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4.69
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6
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The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
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J Virol
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2005
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3.63
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7
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Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.
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Ann Med
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2006
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2.65
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8
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MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population.
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J Natl Cancer Inst
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2005
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2.57
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9
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Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.
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Virology
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2006
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1.59
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10
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Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.
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PLoS Genet
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2010
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1.56
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11
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Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping.
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BMC Genet
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2008
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1.53
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12
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Association assessment of copy number polymorphism and risk of age-related macular degeneration.
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Ophthalmology
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2011
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1.46
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13
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Genome-wide association studies of cancer.
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J Clin Oncol
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2010
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1.45
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14
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Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.
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J Biol Chem
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2007
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1.41
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15
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An exhaustive DNA micro-satellite map of the human genome using high performance computing.
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Genomics
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2003
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1.33
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16
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Unique features of TRIM5alpha among closely related human TRIM family members.
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Virology
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2006
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1.33
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17
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New insights on the evolution of the SMN1 and SMN2 region: simulation and meta-analysis for allele and haplotype frequency calculations.
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Eur J Hum Genet
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2004
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1.28
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18
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Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.
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Arch Gen Psychiatry
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2010
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1.24
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19
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Multilocus analysis of age-related macular degeneration.
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Eur J Hum Genet
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2009
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1.18
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20
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The 6q22.33 locus and breast cancer susceptibility.
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Cancer Epidemiol Biomarkers Prev
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2009
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1.13
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21
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UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.
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PLoS One
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2010
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1.12
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22
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The signatures of autozygosity among patients with colorectal cancer.
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Cancer Res
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2008
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1.10
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23
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Partial retraction. Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.
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Science
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2011
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1.10
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24
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Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region.
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Nucleic Acids Res
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2006
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1.03
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25
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Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population.
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J Acquir Immune Defic Syndr
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2005
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0.95
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26
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CYP1A1 and GSTM1 polymorphisms in relation to lung cancer risk in Chinese women.
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Cancer Lett
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2004
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0.94
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27
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Somatic alterations contributing to metastasis of a castration-resistant prostate cancer.
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Hum Mutat
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2013
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0.92
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28
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Molecular evolutionary analysis of ABCB5: the ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms.
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PLoS One
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2011
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0.91
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29
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Strong association of fascin expression with triple negative breast cancer and basal-like phenotype in African-American women.
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J Clin Pathol
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2013
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0.88
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30
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Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers.
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Hum Genet
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2011
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0.87
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31
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Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population.
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Cell Host Microbe
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2009
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0.85
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32
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Retrospective family study of childhood medulloblastoma.
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Am J Med Genet A
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2005
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0.81
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33
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Bayesian risk assessment in genetic testing for autosomal dominant disorders with age-dependent penetrance.
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J Genet Couns
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2007
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0.81
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34
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Bayesian analysis for cystic fibrosis risks in prenatal and carrier screening.
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Genet Med
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2004
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0.80
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35
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Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.
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PLoS One
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2012
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0.80
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36
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An analysis pipeline for genome-wide association studies.
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Cancer Inform
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2008
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0.75
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37
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Counseling molecular diagnostics.
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Drug Discov Today
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2002
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0.75
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38
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Risk calculations for cystic fibrosis in neonatal screening by immunoreactive trypsinogen and CFTR mutation tests.
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Genet Med
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2005
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0.75
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