Published in J Cancer on September 01, 2010
HIF-1α signaling by airway epithelial cell K-α1-tubulin: role in fibrosis and chronic rejection of human lung allografts. Cell Immunol (2011) 0.97
p16 Stimulates CDC42-dependent migration of hepatocellular carcinoma cells. PLoS One (2013) 0.85
Putative biomarkers and targets of estrogen receptor negative human breast cancer. Int J Mol Sci (2011) 0.85
Inhibition of Breast Tumor Cell Growth by Ectopic Expression of p16/INK4A Via Combined Effects of Cell Cycle Arrest, Senescence and Apoptotic Induction, and Angiogenesis Inhibition. J Cancer (2012) 0.83
Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia. J Cell Sci (2012) 0.81
Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death. Carcinogenesis (2015) 0.77
Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line. Biol Res (2016) 0.77
Targeting HIF-1 for cancer therapy. Nat Rev Cancer (2003) 28.01
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol (1996) 15.20
Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer (2003) 13.01
Regulation of cancer cell motility through actin reorganization. Cancer Sci (2005) 3.87
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst (2003) 2.91
Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia (2007) 2.03
HIF-1α and HIF-2α correlate with migration and invasion in gastric cancer. Cancer Biol Ther (2010) 1.83
Targeting gene expression to hypoxic tumor cells. Nat Med (1997) 1.82
Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models. Cancer Res (2002) 1.59
Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. FASEB J (2005) 1.56
The role of hypoxia-inducible factors in cancer. Cell Mol Life Sci (2007) 1.33
The molecular players of sperm-egg fusion in mammals. Semin Cell Dev Biol (2006) 1.31
Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation. Cancer Res (1999) 1.26
Inhibition of spontaneous breast cancer metastasis by anti-Thomsen-Friedenreich antigen monoclonal antibody JAA-F11. Neoplasia (2006) 1.23
The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem (2003) 1.14
Hypoxia-inducible factor-1alpha is associated with risk of aggressive behavior and tumor angiogenesis in gastrointestinal stromal tumor. Jpn J Clin Oncol (2005) 1.13
mTOR signaling in cancer cell motility and tumor metastasis. Crit Rev Eukaryot Gene Expr (2010) 1.13
A specific cell surface glycoconjugate controlling cell motility: evidence by functional monoclonal antibodies that inhibit cell motility and tumor cell metastasis. Biochemistry (1991) 1.07
Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells. Cancer Res (2010) 1.04
Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis. Cancer Ther (2007) 1.02
Suppression of pulmonary metastasis using adenovirally motility related protein-1 (MRP-1/CD9) gene delivery. Oncogene (2000) 0.97
Vitexin, an HIF-1alpha inhibitor, has anti-metastatic potential in PC12 cells. Mol Cells (2006) 0.96
p16 Modulates VEGF expression via its interaction with HIF-1alpha in breast cancer cells. Cancer Invest (2010) 0.91
p16INK4A as a human tumor suppressor. Biochim Biophys Acta (1996) 0.88
CD9 protein appears on growing mouse oocytes at the time when they develop the ability to fuse with spermatozoa. Zygote (2006) 0.80
Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem (2005) 6.13
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat Immunol (2007) 5.33
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nat Neurosci (2010) 4.28
Functional nucleic acid sensors. Chem Rev (2009) 3.32
A colorimetric lead biosensor using DNAzyme-directed assembly of gold nanoparticles. J Am Chem Soc (2003) 2.77
Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles. Angew Chem Int Ed Engl (2005) 2.45
The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clin Cancer Res (2011) 2.09
Act1, a U-box E3 ubiquitin ligase for IL-17 signaling. Sci Signal (2009) 2.05
Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets. Nat Chem (2011) 1.93
Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol (2011) 1.77
Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth. J Natl Cancer Inst (2010) 1.74
Rationally tuning the reduction potential of a single cupredoxin beyond the natural range. Nature (2009) 1.68
Mentoring. Linking student interests to science curricula. Science (2007) 1.68
Agonistic monoclonal antibodies potentiate tumorigenic and invasive activities of splicing variant of the RON receptor tyrosine kinase. Cancer Biol Ther (2006) 1.67
The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation. J Immunol (2009) 1.67
Validation of the simplified criteria for diagnosis of autoimmune hepatitis in Chinese patients. J Hepatol (2010) 1.63
Dissecting metal ion-dependent folding and catalysis of a single DNAzyme. Nat Chem Biol (2007) 1.63
ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecol Oncol (2013) 1.61
Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group. Leuk Res (2009) 1.60
Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes. Nat Protoc (2006) 1.60
Rational design of a structural and functional nitric oxide reductase. Nature (2009) 1.60
Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res (2006) 1.59
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res (2005) 1.56
A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity. Proc Natl Acad Sci U S A (2007) 1.56
Unique autonomic profile of the pulmonary veins and posterior left atrium. J Am Coll Cardiol (2007) 1.56
Soluble receptor activator of nuclear factor kappaB Fc diminishes prostate cancer progression in bone. Cancer Res (2003) 1.55
Antimicrobial susceptibility testing using high surface-to-volume ratio microchannels. Anal Chem (2010) 1.54
Accelerated color change of gold nanoparticles assembled by DNAzymes for simple and fast colorimetric Pb2+ detection. J Am Chem Soc (2004) 1.53
A modular microfluidic architecture for integrated biochemical analysis. Proc Natl Acad Sci U S A (2005) 1.52
Reversible cell-specific drug delivery with aptamer-functionalized liposomes. Angew Chem Int Ed Engl (2009) 1.50
Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification. J Biol Chem (2006) 1.48
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients. Clin Cancer Res (2011) 1.47
Competencies: a cure for pre-med curriculum. Science (2011) 1.47
Meta-analysis of the relationship between Parkinson disease and melanoma. Neurology (2011) 1.45
Tumour necrosis factor-α and its receptors in the beneficial effects of vagal stimulation after myocardial infarction in rats. Clin Exp Pharmacol Physiol (2011) 1.45
Laser-layered microfabrication of spatially patterned functionalized tissue-engineering scaffolds. J Biomed Mater Res B Appl Biomater (2005) 1.44
Pediatric video laryngoscope versus direct laryngoscope: a meta-analysis of randomized controlled trials. Paediatr Anaesth (2014) 1.42
Retracted Integrated gene network analysis and text mining revealing PIK3R1 regulated by miR-127 in human bladder cancer. Eur J Med Res (2013) 1.39
Effects of norepinephrine on kidney in a swine model of cardiopulmonary resuscitation. Am J Emerg Med (2010) 1.39
A DNAzyme catalytic beacon sensor for paramagnetic Cu2+ ions in aqueous solution with high sensitivity and selectivity. J Am Chem Soc (2007) 1.39
Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells. J Cell Biochem (2008) 1.38
A simple and sensitive "dipstick" test in serum based on lateral flow separation of aptamer-linked nanostructures. Angew Chem Int Ed Engl (2006) 1.37
Novel diagnostic biomarkers for prostate cancer. J Cancer (2010) 1.36
Immobilized nerve growth factor and microtopography have distinct effects on polarization versus axon elongation in hippocampal cells in culture. Biomaterials (2006) 1.36
Rational design of "turn-on" allosteric DNAzyme catalytic beacons for aqueous mercury ions with ultrahigh sensitivity and selectivity. Angew Chem Int Ed Engl (2007) 1.35
CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway. Cancer Res (2008) 1.33
Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids. J Am Chem Soc (2006) 1.33
Adenosine-dependent assembly of aptazyme-functionalized gold nanoparticles and its application as a colorimetric biosensor. Anal Chem (2004) 1.30
Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin. Proc Natl Acad Sci U S A (2010) 1.29
Improving fluorescent DNAzyme biosensors by combining inter- and intramolecular quenchers. Anal Chem (2003) 1.29
Highly sensitive and selective colorimetric sensors for uranyl (UO2(2+)): development and comparison of labeled and label-free DNAzyme-gold nanoparticle systems. J Am Chem Soc (2008) 1.28
MRI detection of thrombin with aptamer functionalized superparamagnetic iron oxide nanoparticles. Bioconjug Chem (2008) 1.26
FRET study of a trifluorophore-labeled DNAzyme. J Am Chem Soc (2002) 1.24
FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages. Diabetes (2009) 1.22
A lead-dependent DNAzyme with a two-step mechanism. Biochemistry (2003) 1.22
3D printing and neurosurgery--ready for prime time? World Neurosurg (2013) 1.22
Oxygenated cembranoids from the cultured and wild-type soft corals Sinularia flexibilis. Chem Pharm Bull (Tokyo) (2009) 1.21
Nanoscale patterns of oligonucleotides formed by electrohydrodynamic jet printing with applications in biosensing and nanomaterials assembly. Nano Lett (2008) 1.21
The role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin. Proc Natl Acad Sci U S A (2003) 1.20
Stimuli-responsive disassembly of nanoparticle aggregates for light-up colorimetric sensing. J Am Chem Soc (2005) 1.20
Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers. PLoS One (2011) 1.20
Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction. Proc Natl Acad Sci U S A (2003) 1.20
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response. J Immunol (2009) 1.19
Toward an understanding of the molecular mechanism for successful blood feeding by coupling proteomics analysis with pharmacological testing of horsefly salivary glands. Mol Cell Proteomics (2007) 1.17
Arthroscopic Bankart repair combined with remplissage technique for the treatment of anterior shoulder instability with engaging Hill-Sachs lesion: a report of 49 cases with a minimum 2-year follow-up. Am J Sports Med (2011) 1.17
Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt. Int J Pharm (2009) 1.16
Multimodality data integration in epilepsy. Int J Biomed Imaging (2007) 1.16
Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids. J Am Chem Soc (2003) 1.15
Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates. Adv Drug Deliv Rev (2010) 1.14
Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers. Chem Rev (2014) 1.13
CSF biomarker changes precede symptom onset of mild cognitive impairment. Neurology (2013) 1.13
An engineered azurin variant containing a selenocysteine copper ligand. J Am Chem Soc (2002) 1.12
Pd(II)-catalyzed hydroxyl-directed C-H activation/C-O cyclization: expedient construction of dihydrobenzofurans. J Am Chem Soc (2010) 1.12
Bioactive cembranoids from the dongsha atoll soft coral Sarcophyton crassocaule. Mar Drugs (2011) 1.11
Androgen deprivation by activating the liver X receptor. Endocrinology (2008) 1.10
Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles. Chem Commun (Camb) (2007) 1.10
Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener. Angew Chem Int Ed Engl (2007) 1.10
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Hum Genet (2012) 1.09
The selenocysteine-substituted blue copper center: spectroscopic investigations of Cys112SeCys Pseudomonas aeruginosa azurin. J Am Chem Soc (2004) 1.09
Uptake of folate-conjugated albumin nanoparticles to the SKOV3 cells. Int J Pharm (2004) 1.09
General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription factor 4 and runt-related transcription factor 2. J Biol Chem (2008) 1.09
Smart "turn-on" magnetic resonance contrast agents based on aptamer-functionalized superparamagnetic iron oxide nanoparticles. Chembiochem (2007) 1.08
A site-selective dual anchoring strategy for artificial metalloprotein design. J Am Chem Soc (2004) 1.07
Biomimetic surface engineering of lanthanide-doped upconversion nanoparticles as versatile bioprobes. Angew Chem Int Ed Engl (2012) 1.07
Cognitive changes preceding clinical symptom onset of mild cognitive impairment and relationship to ApoE genotype. Curr Alzheimer Res (2014) 1.07
Metal ion sensors based on DNAzymes and related DNA molecules. Annu Rev Anal Chem (Palo Alto Calif) (2011) 1.06
Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma. World J Gastroenterol (2002) 1.06
Aptamer-based origami paper analytical device for electrochemical detection of adenosine. Angew Chem Int Ed Engl (2012) 1.06
Is dexmedetomidine superior to midazolam as a premedication in children? A meta-analysis of randomized controlled trials. Paediatr Anaesth (2014) 1.05
Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. Eur J Pharm Biopharm (2012) 1.05
DNA aptamer functionalized nanomaterials for intracellular analysis, cancer cell imaging and drug delivery. Curr Opin Chem Biol (2012) 1.05
Abasic site-containing DNAzyme and aptamer for label-free fluorescent detection of Pb(2+) and adenosine with high sensitivity, selectivity, and tunable dynamic range. J Am Chem Soc (2009) 1.04
A DNAzyme-gold nanoparticle probe for uranyl ion in living cells. J Am Chem Soc (2013) 1.03
Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions in vivo. Neoplasia (2009) 1.03
Using commercially available personal glucose meters for portable quantification of DNA. Anal Chem (2012) 1.03
Suppression of breast cancer metastasis through the inhibition of VEGF-mediated tumor angiogenesis. Cancer Ther (2007) 1.02
Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation. Int J Nanomedicine (2011) 1.02
Phylogenetics of wigeons and allies (Anatidae: Anas): the importance of sampling multiple loci and multiple individuals. Mol Phylogenet Evol (2005) 1.01