Published in J Cell Biol on October 11, 2010
The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs. Bioinformatics (2013) 2.31
DENN domain proteins: regulators of Rab GTPases. J Biol Chem (2011) 1.81
Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles. J Cell Biol (2012) 1.59
Review series: Rab GTPases and membrane identity: causal or inconsequential? J Cell Biol (2013) 1.56
Identification of an oncogenic RAB protein. Science (2015) 1.56
Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet (2011) 1.51
Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases. J Cell Biol (2013) 1.43
Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission. J Cell Biol (2010) 1.43
Rab proteins and the compartmentalization of the endosomal system. Cold Spring Harb Perspect Biol (2014) 1.40
Coordination between RAB GTPase and phosphoinositide regulation and functions. Nat Rev Mol Cell Biol (2012) 1.35
A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis. Dev Cell (2013) 1.34
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. Open Biol (2012) 1.29
RabGEFs are a major determinant for specific Rab membrane targeting. J Cell Biol (2013) 1.26
Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells. Dev Cell (2012) 1.23
An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss. Genome Biol (2015) 1.19
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Proc Natl Acad Sci U S A (2011) 1.15
Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells. PLoS Biol (2012) 1.13
Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion. EMBO Rep (2015) 1.09
Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. J Biol Chem (2011) 1.07
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation. Elife (2014) 1.02
The autophagic roles of Rab small GTPases and their upstream regulators: a review. Autophagy (2014) 1.00
Prognostic impact of expression and methylation status of DENN/MADD domain-containing protein 2D in gastric cancer. Gastric Cancer (2014) 1.00
Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy. EMBO Rep (2015) 0.99
eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation. Genes Dev (2013) 0.99
Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Mol Biol Cell (2013) 0.99
Rab18 and a Rab18 GEF complex are required for normal ER structure. J Cell Biol (2014) 0.99
Discovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-II. Small GTPases (2013) 0.98
DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior. J Cell Biol (2015) 0.97
Genetics of the polycystic ovary syndrome. Mol Cell Endocrinol (2012) 0.97
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. J Cell Sci (2014) 0.96
Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton. Mol Biol Cell (2011) 0.96
Expression of RABEX-5 and its clinical significance in prostate cancer. J Exp Clin Cancer Res (2014) 0.94
Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit. Proc Natl Acad Sci U S A (2012) 0.94
Rab GTPase localization and Rab cascades in Golgi transport. Biochem Soc Trans (2012) 0.92
Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast. J Biol Chem (2013) 0.91
Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. Mol Biol Cell (2014) 0.88
Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2. PLoS One (2012) 0.88
Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. Mol Biol Cell (2012) 0.87
Whole exome sequencing in females with autism implicates novel and candidate genes. Int J Mol Sci (2015) 0.87
Functional characterisation of the YIPF protein family in mammalian cells. Histochem Cell Biol (2016) 0.87
Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts. J Biol Chem (2014) 0.86
Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding. Traffic (2011) 0.86
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS. Brain Res (2016) 0.85
The Genetics of Infertility: Current Status of the Field. Curr Genet Med Rep (2013) 0.85
Rabex-5 protein regulates dendritic localization of small GTPase Rab17 and neurite morphogenesis in hippocampal neurons. J Biol Chem (2013) 0.85
C. elegans as a model for membrane traffic. WormBook (2014) 0.84
Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice. PLoS One (2014) 0.83
Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles. Invest Ophthalmol Vis Sci (2013) 0.83
A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Sci Adv (2016) 0.83
TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun (2015) 0.83
Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction. J Biol Chem (2017) 0.83
C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling. Mol Biol Cell (2016) 0.83
Mediation of clathrin-dependent trafficking during cytokinesis and cell expansion by Arabidopsis stomatal cytokinesis defective proteins. Plant Cell (2013) 0.82
Identifying candidate genes for Type 2 Diabetes Mellitus and obesity through gene expression profiling in multiple tissues or cells. J Diabetes Res (2013) 0.81
Charcot-Marie-Tooth disease and intracellular traffic. Prog Neurobiol (2012) 0.81
Intermediates in the guanine nucleotide exchange reaction of Rab8 protein catalyzed by guanine nucleotide exchange factors Rabin8 and GRAB. J Biol Chem (2013) 0.80
Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D. Sci Rep (2016) 0.80
Building from the Ground up: Basement Membranes in Drosophila Development. Curr Top Membr (2015) 0.79
The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to the Schwann cell cytoplasm and endomembrane compartments, where they depend upon each other to achieve wild-type levels of protein expression. Hum Mol Genet (2013) 0.79
TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells. Mol Biol Cell (2014) 0.79
Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners. Mol Biol Cell (2016) 0.79
Rab10 joins the ER social network. Nat Cell Biol (2013) 0.78
Mapping the interactions between a RUN domain from DENND5/Rab6IP1 and sorting nexin 1. PLoS One (2012) 0.78
Influenza Virus Induces Cholesterol-Enriched Endocytic Recycling Compartments for Budozone Formation via Cell Cycle-Independent Centrosome Maturation. PLoS Pathog (2015) 0.78
Rab9A is required for delivery of cargo from recycling endosomes to melanosomes. Pigment Cell Melanoma Res (2016) 0.78
IG20/MADD plays a critical role in glucose-induced insulin secretion. Diabetes (2013) 0.78
Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol (2016) 0.78
Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis. Oncoscience (2014) 0.77
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells. J Cell Biol (2016) 0.77
RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport. PLoS Genet (2015) 0.77
piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation. Stem Cell Reports (2015) 0.76
Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest. Sci Rep (2015) 0.76
Small GTPase Rab12 regulates transferrin receptor degradation: Implications for a novel membrane trafficking pathway from recycling endosomes to lysosomes. Cell Logist (2011) 0.76
Rabex-5 determines the neurite localization of its downstream Rab proteins in hippocampal neurons. Commun Integr Biol (2013) 0.76
Regulation of Cancer Cell Behavior by the Small GTPase Rab13. J Biol Chem (2016) 0.76
Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors. J Biol Chem (2015) 0.76
Measuring Rab GTPase-activating protein (GAP) activity in live cells and extracts. Methods Mol Biol (2015) 0.75
Epileptic Encephalopathy Caused by Mutations in the Guanine Nucleotide Exchange Factor DENND5A. Am J Hum Genet (2016) 0.75
Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors. PLoS One (2016) 0.75
C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease. Traffic (2017) 0.75
FLCN: The causative gene for Birt-Hogg-Dubé syndrome. Gene (2017) 0.75
MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res (2004) 168.89
Clustal W and Clustal X version 2.0. Bioinformatics (2007) 126.47
Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res (2003) 38.75
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol (2008) 38.00
Jalview Version 2--a multiple sequence alignment editor and analysis workbench. Bioinformatics (2009) 31.84
Rab proteins as membrane organizers. Nat Rev Mol Cell Biol (2001) 19.95
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell (2007) 10.75
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature (1996) 9.36
Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J (1993) 4.35
Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J Cell Biol (1997) 3.94
Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol (2007) 3.67
Targeting Rab GTPases to distinct membrane compartments. Nat Rev Mol Cell Biol (2004) 3.52
Organelle identity and the signposts for membrane traffic. Nature (2005) 3.36
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism. Nature (2006) 3.04
The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature (2007) 3.01
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol (1994) 2.95
The genome of Naegleria gruberi illuminates early eukaryotic versatility. Cell (2010) 2.93
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
Rab GEFs and GAPs. Curr Opin Cell Biol (2010) 2.73
Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit. Nat Cell Biol (2005) 2.70
Prediction of protein binding regions in disordered proteins. PLoS Comput Biol (2009) 2.69
A GTPase-activating protein controls Rab5 function in endocytic trafficking. Nat Cell Biol (2005) 2.68
The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell (2008) 2.61
ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Res (2009) 2.59
Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts. J Cell Biol (1996) 2.57
TRAPP stimulates guanine nucleotide exchange on Ypt1p. J Cell Biol (2000) 2.24
The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7. Curr Biol (2010) 2.19
Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. J Cell Sci (2007) 2.18
Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5. Cell (2004) 2.17
Prediction of disordered regions in proteins based on the meta approach. Bioinformatics (2008) 2.09
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J (2000) 2.04
The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes. Mol Cell (2010) 1.97
Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma. Am J Hum Genet (2003) 1.96
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J Cell Biol (2007) 1.95
A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. Mol Biol Cell (2002) 1.93
Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells. Mol Biol Cell (2006) 1.92
Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly. Am J Hum Genet (2010) 1.87
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules. J Biol Chem (2002) 1.86
aex-3 encodes a novel regulator of presynaptic activity in C. elegans. Neuron (1997) 1.86
The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci (2007) 1.80
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A novel Rab9 effector required for endosome-to-TGN transport. J Cell Biol (1997) 1.69
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Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein. EMBO J (2008) 1.65
Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans. Mol Biol Cell (2006) 1.61
Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic (2006) 1.61
Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins. J Biol Chem (1997) 1.59
SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting. Semin Cell Dev Biol (2009) 1.49
A catalytic coiled coil: structural insights into the activation of the Rab GTPase Sec4p by Sec2p. Mol Cell (2007) 1.48
Lightoid and Claret: a rab GTPase and its putative guanine nucleotide exchange factor in biogenesis of Drosophila eye pigment granules. Proc Natl Acad Sci U S A (2004) 1.34
Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells. J Cell Biol (2008) 1.30
Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. Dev Cell (2008) 1.28
uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways. Biochem Biophys Res Commun (2001) 1.25
Crystal structure of the Sec4p.Sec2p complex in the nucleotide exchanging intermediate state. Proc Natl Acad Sci U S A (2007) 1.24
RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport. Cell (2009) 1.23
Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. J Biol Chem (2010) 1.19
Sec2 is a highly efficient exchange factor for the Rab protein Sec4. J Mol Biol (2006) 1.18
The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells. Biochem J (2002) 1.15
Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein. J Biol Chem (1998) 1.15
The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery. J Biol Chem (2010) 1.09
Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes. J Biol Chem (2008) 1.07
Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway. Mol Biol Cell (2007) 1.05
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A (2008) 0.98
Assay and properties of rab6 interaction with dynein-dynactin complexes. Methods Enzymol (2005) 0.97
Assay and functional properties of Rabkinesin-6/Rab6-KIFL/MKlp2 in cytokinesis. Methods Enzymol (2005) 0.88
A chemical genetic screen for modulators of exocytic transport identifies inhibitors of a transport mechanism linked to GTR2 function. Eukaryot Cell (2009) 0.82
Disruption of ST5 is associated with mental retardation and multiple congenital anomalies. J Med Genet (2009) 0.81
Purification and properties of Rab3 GEP (DENN/MADD). Methods Enzymol (2005) 0.81
Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol (2007) 3.67
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol (2003) 3.12
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy (2010) 2.91
A GTPase-activating protein controls Rab5 function in endocytic trafficking. Nat Cell Biol (2005) 2.68
Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nat Cell Biol (2007) 2.54
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol (2010) 2.52
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol (2004) 2.44
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell (2007) 2.38
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. J Cell Biol (2004) 2.29
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase. Nucleic Acids Res (2007) 2.19
Golgins and GTPases, giving identity and structure to the Golgi apparatus. Biochim Biophys Acta (2005) 2.18
Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. J Cell Sci (2007) 2.18
KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol (2006) 2.06
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes. J Cell Biol (2012) 2.00
Calicivirus translation initiation requires an interaction between VPg and eIF 4 E. EMBO Rep (2005) 1.98
The UIM domain of Hrs couples receptor sorting to vesicle formation. J Cell Sci (2003) 1.97
Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling. EMBO J (2005) 1.96
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J Cell Biol (2007) 1.95
Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis. J Cell Biol (2002) 1.89
The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes. Curr Biol (2002) 1.84
Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout. Mol Biol Cell (2003) 1.82
BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor. Curr Biol (2012) 1.74
Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2. J Cell Biol (2010) 1.73
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biol (2013) 1.62
Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases. Curr Biol (2003) 1.61
Genomic determinants of sporulation in Bacilli and Clostridia: towards the minimal set of sporulation-specific genes. Environ Microbiol (2012) 1.59
Plant-like traits associated with metabolism of Trypanosoma parasites. Proc Natl Acad Sci U S A (2003) 1.59
Deubiquitylases from genes to organism. Physiol Rev (2013) 1.54
Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission. J Cell Biol (2010) 1.43
Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi. Mol Biol Cell (2008) 1.43
The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. J Cell Biol (2007) 1.42
Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. Nat Genet (2008) 1.40
Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1. Genome Biol (2008) 1.39
Inheritance and biogenesis of organelles in the secretory pathway. Nat Rev Mol Cell Biol (2007) 1.38
Plant alpha-amylase inhibitors and their interaction with insect alpha-amylases. Eur J Biochem (2002) 1.38
The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment. J Cell Biol (2011) 1.36
Loss-of-function mutations in RAB18 cause Warburg micro syndrome. Am J Hum Genet (2011) 1.36
Convergence of cell cycle regulation and growth factor signals on GRASP65. J Biol Chem (2005) 1.35
Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer. Open Biol (2012) 1.29
Autophagy in protists. Autophagy (2011) 1.29
Cooperation between mitotic kinesins controls the late stages of cytokinesis. Curr Biol (2006) 1.28
Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase. Plant Physiol (2004) 1.27
The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection. Nucleic Acids Res (2013) 1.26
RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. J Biol Chem (2011) 1.25
Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. J Cell Sci (2005) 1.25
Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells. Dev Cell (2012) 1.23
The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation. Mol Cell (2013) 1.23
CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis. J Cell Biol (2012) 1.20
Autophagy in parasitic protists: unique features and drug targets. Mol Biochem Parasitol (2011) 1.19
Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. J Cell Biol (2005) 1.18
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Proc Natl Acad Sci U S A (2011) 1.15
AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models. Acta Crystallogr D Biol Crystallogr (2012) 1.15
Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol (2013) 1.13
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am J Hum Genet (2013) 1.11
Order within a mosaic distribution of mitochondrial c-type cytochrome biogenesis systems? FEBS J (2008) 1.11
Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions. Mol Biol Cell (2012) 1.06
Autophagy and related processes in trypanosomatids: insights from genomic and bioinformatic analyses. Autophagy (2006) 1.05
Cathepsin L digestion of nanobioconjugates upon endocytosis. ACS Nano (2009) 1.05
Dynamics of Golgi matrix proteins after the blockage of ER to Golgi transport. J Biochem (2004) 1.05
Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation. J Cell Biol (2012) 1.04
Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics. FEBS J (2007) 1.03
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation. Elife (2014) 1.02
Mining metagenomic data for novel domains: BACON, a new carbohydrate-binding module. FEBS Lett (2010) 1.02
L-Ascorbic acid 6-hexadecanoate, a potent hyaluronidase inhibitor. X-ray structure and molecular modeling of enzyme-inhibitor complexes. J Biol Chem (2004) 1.02
A new type of antimicrobial protein with multiple histidines from the hard tick, Amblyomma hebraeum. FASEB J (2004) 1.00
Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment. J Virol (2011) 1.00
Melanoma-associated mutations in protein phosphatase 6 cause chromosome instability and DNA damage owing to dysregulated Aurora-A. J Cell Sci (2013) 0.98
Discovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-II. Small GTPases (2013) 0.98
Assay and properties of rab6 interaction with dynein-dynactin complexes. Methods Enzymol (2005) 0.97
Identification of differentially expressed cDNA sequences in ovaries of sexual and apomictic plants of Brachiaria brizantha. Plant Mol Biol (2003) 0.97
The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes. J Cell Sci (2014) 0.96
CUCU modification of mRNA promotes decapping and transcript degradation in Aspergillus nidulans. Mol Cell Biol (2009) 0.95
Inhibition of trypsin by cowpea thionin: characterization, molecular modeling, and docking. Proteins (2002) 0.95
The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles. Mol Biol Cell (2012) 0.94
The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis. FEBS Lett (2002) 0.93
Characterization and functional investigation of an Arabidopsis cDNA encoding a homologue to the d-PGMase superfamily. J Exp Bot (2005) 0.93
RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36. J Biol Chem (2012) 0.93
Regulation of ecdysteroid signalling during Drosophila development: identification, characterization and modelling of ecdysone oxidase, an enzyme involved in control of ligand concentration. Biochem J (2005) 0.93
Sequence analysis and characterization of a novel fibronectin-binding repeat domain from the surface of Streptococcus pneumoniae. OMICS (2004) 0.91
Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif? PLoS One (2012) 0.90
Improving Cry8Ka toxin activity towards the cotton boll weevil (Anthonomus grandis). BMC Biotechnol (2011) 0.89
Cell motility in chronic lymphocytic leukemia: defective Rap1 and alphaLbeta2 activation by chemokine. Cancer Res (2008) 0.88
Assay and functional properties of Rabkinesin-6/Rab6-KIFL/MKlp2 in cytokinesis. Methods Enzymol (2005) 0.88
An unsuspected ecdysteroid/steroid phosphatase activity in the key T-cell regulator, Sts-1: surprising relationship to insect ecdysteroid phosphate phosphatase. Proteins (2007) 0.87
mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation. Mol Cell Biol (2012) 0.87
The structure-function relationship in the clostripain family of peptidases. Eur J Biochem (2004) 0.87
Structural variability of the ubiquitin specific protease DUSP-UBL double domains. FEBS Lett (2011) 0.86
Analysis of Rab GTPase and GTPase-activating protein function at primary cilia. Methods Enzymol (2008) 0.85
Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase. Eur J Biochem (2003) 0.84
Characterization of the ligandin site of maize glutathione S-transferase I. Biochem J (2004) 0.84
The crystal structure of Trypanosoma brucei enolase: visualisation of the inhibitory metal binding site III and potential as target for selective, irreversible inhibition. J Mol Biol (2003) 0.84
Evolutionary analysis of fructose 2,6-bisphosphate metabolism. IUBMB Life (2006) 0.84
Kinases regulating Golgi apparatus structure and function. Biochem Soc Symp (2005) 0.83
Identification, characterization and essentiality of the unusual peroxin 13 from Trypanosoma brucei. Biochim Biophys Acta (2009) 0.83