Published in J Cell Sci on June 15, 2007
Retromer. Curr Opin Cell Biol (2008) 3.89
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Sorting nexins provide diversity for retromer-dependent trafficking events. Nat Cell Biol (2011) 2.32
Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5. J Cell Sci (2009) 2.30
Shiga toxins--from cell biology to biomedical applications. Nat Rev Microbiol (2009) 2.19
Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. J Cell Biol (2010) 2.11
The retromer complex - endosomal protein recycling and beyond. J Cell Sci (2012) 2.08
The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev Cell (2009) 1.99
Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy. Mol Biol Cell (2012) 1.90
Retromer terminates the generation of cAMP by internalized PTH receptors. Nat Chem Biol (2011) 1.88
A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. J Cell Biol (2008) 1.63
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol (2012) 1.60
Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3. EMBO J (2008) 1.59
SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting. Semin Cell Dev Biol (2009) 1.49
Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. Mol Biol Cell (2008) 1.49
Retromer: a master conductor of endosome sorting. Cold Spring Harb Perspect Biol (2014) 1.46
Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8. EMBO J (2009) 1.46
Multivesicular bodies: co-ordinated progression to maturity. Curr Opin Cell Biol (2008) 1.45
PIKfyve regulation of endosome-linked pathways. Traffic (2009) 1.39
EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology. J Cell Sci (2009) 1.37
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel) (2010) 1.34
Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei. J Cell Sci (2011) 1.29
Manganese blocks intracellular trafficking of Shiga toxin and protects against Shiga toxicosis. Science (2012) 1.25
Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. Mol Neurodegener (2010) 1.25
The COG complex, Rab6 and COPI define a novel Golgi retrograde trafficking pathway that is exploited by SubAB toxin. Traffic (2009) 1.23
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J Biol Chem (2008) 1.22
Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome. Mol Biol Cell (2008) 1.21
A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. J Biol Chem (2010) 1.10
The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network. Mol Biol Cell (2007) 1.07
Retrograde transport of protein toxins through the Golgi apparatus. Histochem Cell Biol (2013) 1.03
The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry. Virology (2012) 1.00
A retrograde trafficking inhibitor of ricin and Shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses. MBio (2013) 1.00
Physiology and pathology of endosome-to-Golgi retrograde sorting. Traffic (2011) 0.99
The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step. J Cell Biol (2010) 0.98
The complex ultrastructure of the endolysosomal system. Cold Spring Harb Perspect Biol (2014) 0.97
Retrograde Shiga toxin trafficking is regulated by ARHGAP21 and Cdc42. Mol Biol Cell (2009) 0.97
Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin. J Cell Sci (2011) 0.96
Entry at the trans-face of the Golgi. Cold Spring Harb Perspect Biol (2011) 0.94
Diversity and impact of prokaryotic toxins on aquatic environments: a review. Toxins (Basel) (2010) 0.94
Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins. Front Cell Infect Microbiol (2012) 0.92
Sorting in early endosomes reveals connections to docking- and fusion-associated factors. Proc Natl Acad Sci U S A (2009) 0.91
AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis. Mol Biol Cell (2007) 0.91
Retromer guides STxB and CD8-M6PR from early to recycling endosomes, EHD1 guides STxB from recycling endosome to Golgi. Traffic (2012) 0.88
Phosphoinositides in the mammalian endo-lysosomal network. Subcell Biochem (2012) 0.87
FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network. Mol Biol Cell (2010) 0.87
Drosophila liquid facets-Related encodes Golgi epsin and is an essential gene required for cell proliferation, growth, and patterning. Dev Biol (2009) 0.86
Retrograde traffic in the biosynthetic-secretory route. Histochem Cell Biol (2008) 0.85
AGAP2 regulates retrograde transport between early endosomes and the TGN. J Cell Sci (2010) 0.84
Unconventional functions for clathrin, ESCRTs, and other endocytic regulators in the cytoskeleton, cell cycle, nucleus, and beyond: links to human disease. Cold Spring Harb Perspect Biol (2014) 0.84
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin. PLoS One (2012) 0.83
A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2. Traffic (2015) 0.82
Clathrin is not required for SNX-BAR-retromer-mediated carrier formation. J Cell Sci (2012) 0.81
Retrograde trafficking of AB₅ toxins: mechanisms to therapeutics. J Mol Med (Berl) (2013) 0.81
Shiga toxins: intracellular trafficking to the ER leading to activation of host cell stress responses. Toxins (Basel) (2010) 0.80
Uptake and processing of the cytolethal distending toxin by mammalian cells. Toxins (Basel) (2014) 0.80
Arf6 regulation of Gyrating-clathrin. Traffic (2012) 0.78
Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signaling. PLoS One (2012) 0.78
Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol (2016) 0.78
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells. PLoS One (2015) 0.77
Receptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics. J Biol Chem (2015) 0.76
Genome-wide RNAi screen reveals a role for multipass membrane proteins in endosome-to-golgi retrieval. Cell Rep (2014) 0.76
TSSC1 is novel component of the endosomal retrieval machinery. Mol Biol Cell (2016) 0.75
Role of the Retromer Complex in Neurodegenerative Diseases. Front Aging Neurosci (2016) 0.75
The giardial VPS35 retromer subunit is necessary for multimeric complex assembly and interaction with the vacuolar protein sorting receptor. Biochim Biophys Acta (2013) 0.75
Imaging intracellular fluorescent proteins at nanometer resolution. Science (2006) 38.97
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature (2010) 6.26
Exosomal-like vesicles are present in human blood plasma. Int Immunol (2005) 6.04
Exosomes: a common pathway for a specialized function. J Biochem (2006) 5.79
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 4.94
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol (2004) 4.24
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell (2002) 4.13
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol (2014) 3.97
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature (2007) 3.51
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. J Cell Biol (2002) 3.36
Exosome secretion: molecular mechanisms and roles in immune responses. Traffic (2011) 3.36
A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane. EMBO J (2002) 3.35
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Sorting of lysosomal proteins. Biochim Biophys Acta (2008) 2.86
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Nat Struct Mol Biol (2006) 2.85
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
Interactions of GGA3 with the ubiquitin sorting machinery. Nat Cell Biol (2004) 2.63
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell (2002) 2.55
PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer. Cancer Res (2012) 2.43
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 2.28
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes. J Cell Biol (2003) 2.24
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol (2003) 2.12
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat Struct Mol Biol (2006) 2.09
Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol (2005) 2.09
Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature (2002) 2.09
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles (2012) 2.06
Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Mol Cell Biol (2006) 2.05
GM1 structure determines SV40-induced membrane invagination and infection. Nat Cell Biol (2009) 2.04
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
Coatomer-dependent protein delivery to lipid droplets. J Cell Sci (2009) 2.01
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins. Mol Biol Cell (2005) 1.99
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex. Dev Cell (2010) 1.98
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. J Cell Biol (2002) 1.98
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J Virol (2007) 1.90
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol (2004) 1.86
Actin dynamics drive membrane reorganization and scission in clathrin-independent endocytosis. Cell (2010) 1.85
Clathrin-dependent or not: is it still the question? Traffic (2002) 1.85
Endosomes, exosomes and Trojan viruses. Trends Microbiol (2004) 1.84
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease. Nat Genet (2003) 1.77
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol (2005) 1.76
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi network. Mol Biol Cell (2003) 1.70
Genetic analyses of adaptin function from yeast to mammals. Gene (2002) 1.70
The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain. J Biol Chem (2006) 1.68
Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. PLoS Pathog (2010) 1.66
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex. EMBO J (2003) 1.63
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell (2007) 1.63
Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. Dev Cell (2004) 1.62
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60