Published in World J Gastroenterol on October 14, 2010
Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma. Virchows Arch (2011) 1.35
KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues. Int J Mol Sci (2011) 1.17
454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples. Onco Targets Ther (2013) 1.08
A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas. J Exp Clin Cancer Res (2012) 1.04
Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients. World J Gastroenterol (2011) 1.00
KRAS Testing: A Tool for the Implementation of Personalized Medicine. Genes Cancer (2012) 0.81
Validation of a Multiplex Allele-Specific Polymerase Chain Reaction Assay for Detection of KRAS Gene Mutations in Formalin-Fixed, Paraffin-Embedded Tissues from Colorectal Cancer Patients. PLoS One (2016) 0.77
Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pie. J Gastrointest Oncol (2017) 0.75
KRAS Mutation Test in Korean Patients with Colorectal Carcinomas: A Methodological Comparison between Sanger Sequencing and a Real-Time PCR-Based Assay. J Pathol Transl Med (2016) 0.75
K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med (2008) 27.35
Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82
Cetuximab for the treatment of colorectal cancer. N Engl J Med (2007) 13.39
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol (2008) 10.29
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol (2004) 9.73
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol (2005) 8.08
Sensitive sequencing method for KRAS mutation detection by Pyrosequencing. J Mol Diagn (2005) 6.00
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature (1987) 5.46
K-ras mutations in putative preneoplastic lesions in human colon. J Natl Cancer Inst (1993) 1.80
K-ras oncogene mutation as a prognostic marker in non-small cell lung cancer: a combined analysis of 881 cases. Carcinogenesis (1999) 1.67
K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location. Br J Cancer (1994) 1.31
K-ras mutation detection in colorectal cancer using the Pyrosequencing technique. Pathol Res Pract (2007) 1.21
Lack of usefulness of epidermal growth factor receptor expression determination for cetuximab therapy in patients with colorectal cancer. Anticancer Drugs (2006) 1.19
K-ras mutations in sporadic colorectal tumors in Israel: unusual high frequency of codon 13 mutations and evidence for nonhomogeneous representation of mutation subtypes. Dig Dis Sci (2002) 0.97
Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan. Cancer Genet Cytogenet (2005) 0.90
The HBV drug entecavir - effects on HIV-1 replication and resistance. N Engl J Med (2007) 3.20
Serum microRNA expression profile as a biomarker in the diagnosis and prognosis of pancreatic cancer. Clin Chem (2011) 2.42
Everolimus for previously treated advanced gastric cancer: results of the randomized, double-blind, phase III GRANITE-1 study. J Clin Oncol (2013) 2.14
Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy. J Gastroenterol (2015) 2.01
Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality. J Natl Cancer Inst (2012) 1.88
Apparent diffusion coefficient: potential imaging biomarker for prediction and early detection of response to chemotherapy in hepatic metastases. Radiology (2008) 1.85
Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle. Proc Natl Acad Sci U S A (2008) 1.72
A quantitative basis for antiretroviral therapy for HIV-1 infection. Nat Med (2012) 1.68
UGT1A1 predicts outcome in colorectal cancer treated with irinotecan and fluorouracil. World J Gastroenterol (2012) 1.56
Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice. Eur J Pharm Sci (2011) 1.39
Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance. Proc Natl Acad Sci U S A (2011) 1.33
Efficacy and safety of bevacizumab plus chemotherapy in Chinese patients with metastatic colorectal cancer: a randomized phase III ARTIST trial. Chin J Cancer (2011) 1.32
Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Invest New Drugs (2010) 1.25
Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. Proc Natl Acad Sci U S A (2009) 1.19
A phase II trial of paclitaxel and cisplatin in patients with advanced squamous-cell carcinoma of the esophagus. Am J Clin Oncol (2008) 1.16
Methylation of p16 CpG islands associated with malignant transformation of gastric dysplasia in a population-based study. Clin Cancer Res (2004) 1.14
Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population. Gastroenterology (2006) 1.14
Preferential cytolysis of peripheral memory CD4+ T cells by in vitro X4-tropic human immunodeficiency virus type 1 infection before the completion of reverse transcription. J Virol (2008) 1.12
Gastrointestinal stromal tumors treated with imatinib mesylate: apparent diffusion coefficient in the evaluation of therapy response in patients. Radiology (2010) 1.11
Neutrophil count and the inflammation-based glasgow prognostic score predict survival in patients with advanced gastric cancer receiving first-line chemotherapy. Asian Pac J Cancer Prev (2014) 1.10
Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. J Virol (2010) 1.10
Predictive value of serum CEA, CA19-9 and CA72.4 in early diagnosis of recurrence after radical resection of gastric cancer. Hepatogastroenterology (2012) 1.09
Automatic segmentation of the caudate nucleus from human brain MR images. IEEE Trans Med Imaging (2007) 1.09
New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo. Curr Opin Infect Dis (2009) 1.03
Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. Gut (2011) 1.02
Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors. J Hematol Oncol (2011) 0.97
Hippocampal and amygdalar volumes in psychotic and nonpsychotic unipolar depression. Am J Psychiatry (2008) 0.96
EGFR fluorescence in situ hybridization pattern of chromosome 7 disomy predicts resistance to cetuximab in KRAS wild-type metastatic colorectal cancer patients. Clin Cancer Res (2010) 0.95
Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus. Chin J Integr Med (2008) 0.95
Neoadjuvant chemotherapy with FOLFOX: improved outcomes in Chinese patients with locally advanced gastric cancer. J Surg Oncol (2011) 0.94
Emotional primes modulate the responses to others' pain: an ERP study. Exp Brain Res (2012) 0.93
Combination chemotherapy with paclitaxel, cisplatin and fluorouracil for patients with advanced and metastatic gastric or esophagogastric junction adenocarcinoma: a multicenter prospective study. Chin J Cancer Res (2012) 0.91
Thymidine Phosphorylase/β-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel. BMC Cancer (2011) 0.91
Efficacy of imatinib dose escalation in Chinese gastrointestinal stromal tumor patients. World J Gastroenterol (2012) 0.90
Magnetic/upconversion fluorescent NaGdF4:Yb,Er nanoparticle-based dual-modal molecular probes for imaging tiny tumors in vivo. ACS Nano (2013) 0.90
Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history. BMC Microbiol (2008) 0.89
UGT1A1 6/28 polymorphisms could predict irinotecan-induced severe neutropenia not diarrhea in Chinese colorectal cancer patients. Med Oncol (2013) 0.89
Preventive effects of taurine and vitamin C on renal DNA damage of mice exposed to arsenic. J Occup Health (2009) 0.89
Eradication of H pylori infection in a rural population: one-day quadruple therapy versus 7-day triple therapy. World J Gastroenterol (2006) 0.89
Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. J Virol (2011) 0.88
Expressions of Thymidylate Synthase,Thymidine Phosphorylase, Class III β-tubulin, and Excision Repair Cross-complementing Group 1predict Response in Advanced Gastric Cancer Patients Receiving Capecitabine Plus Paclitaxel or Cisplatin. Chin J Cancer Res (2011) 0.88
Impact of KRAS mutation and PTEN expression on cetuximab-treated colorectal cancer. World J Gastroenterol (2010) 0.88
Secondary mutations of c-KIT contribute to acquired resistance to imatinib and decrease efficacy of sunitinib in Chinese patients with gastrointestinal stromal tumors. Med Oncol (2013) 0.88
Folic acid supplementation and cancer risk: a meta-analysis of randomized controlled trials. Int J Cancer (2013) 0.87
Effects of Olig2-overexpressing neural stem cells and myelin basic protein-activated T cells on recovery from spinal cord injury. Neurotherapeutics (2012) 0.86
MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery. Med Oncol (2013) 0.86
Diagnostic accuracy of 18F-FDG-PET in patients with testicular cancer: a meta-analysis. Asian Pac J Cancer Prev (2014) 0.86
Associations of single nucleotide polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with colorectal cancer susceptibility. Asian Pac J Cancer Prev (2014) 0.85
Inhibitory effect of GSPE on RAGE expression induced by advanced glycation end products in endothelial cells. J Cardiovasc Pharmacol (2007) 0.85
[Preterm birth and preterm infants in Beijing regional district]. Zhonghua Fu Chan Ke Za Zhi (2010) 0.85
C-KIT mutations were closely associated with the response to Imatinib in Chinese advanced gastrointestinal stromal tumor patients. Med Oncol (2012) 0.85
Associations between UGT1A1*6/*28 polymorphisms and irinotecan-induced severe toxicity in Chinese gastric or esophageal cancer patients. Med Oncol (2013) 0.84
High level of serum AMBP is associated with poor response to paclitaxel-capecitabine chemotherapy in advanced gastric cancer patients. Med Oncol (2013) 0.84
Identification of bombesin receptor subtype-specific ligands: effect of N-methyl scanning, truncation, substitution, and evaluation of putative reported selective ligands. J Pharmacol Exp Ther (2006) 0.84
Low plasma adiponectin as a potential biomarker for osteonecrosis of the femoral head. J Rheumatol (2010) 0.83
[Polymorphisms of UGT1A gene and irinotecan toxicity in Chinese colorectal cancer patients]. Zhonghua Zhong Liu Za Zhi (2007) 0.83
Evaluation of multi-dimensional outcomes of chronic diseases: a clinical example from China. Arch Gerontol Geriatr (2010) 0.83
Serum HER2 extracellular domain as a potential alternative for tissue HER2 status in metastatic gastric cancer patients. Biomark Med (2014) 0.83
Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway. Acta Pharmacol Sin (2012) 0.83
Serum β -Catenin Levels Associated with the Ratio of RANKL/OPG in Patients with Postmenopausal Osteoporosis. Int J Endocrinol (2013) 0.83
Peroxisome proliferator-activated receptors (PPARs) and their agonists for hypertension and heart failure: are the reagents beneficial or harmful? Int J Cardiol (2008) 0.82
Albuminuria independently predicts cardiovascular and all-cause mortality in a middle-aged and elderly Chinese population. Scand J Clin Lab Invest (2012) 0.82
Oxymatrine improves TNBS-induced colitis in rats by inhibiting the expression of NF-kappaB p65. J Huazhong Univ Sci Technolog Med Sci (2008) 0.82
Bacterial community compositions of tomato (Lycopersicum esculentum Mill.) seeds and plant growth promoting activity of ACC deaminase producing Bacillus subtilis (HYT-12-1) on tomato seedlings. World J Microbiol Biotechnol (2013) 0.82
Proteomics investigation of protein expression changes in ouabain induced apoptosis in human umbilical vein endothelial cells. J Cell Biochem (2008) 0.82
Preharvest L-arginine treatment induced postharvest disease resistance to Botrysis cinerea in tomato fruits. J Agric Food Chem (2011) 0.82
[Study on corresponding areas the liver and lung channels in brain with fMRI]. Zhongguo Zhen Jiu (2007) 0.82
Serum levels of TUBB3 correlate with clinical outcome in Chinese patients with advanced gastric cancer receiving first-line paclitaxel plus capecitabine. Med Oncol (2012) 0.82
RimJ is responsible for N(alpha)-acetylation of thymosin alpha1 in Escherichia coli. Appl Microbiol Biotechnol (2009) 0.82
Scriptaid improves in vitro development and nuclear reprogramming of somatic cell nuclear transfer bovine embryos. Cell Reprogram (2011) 0.82
The multicenter, phase II prospective study of paclitaxel plus capecitabine as first-line chemotherapy in advanced gastric carcinoma. Oncologist (2014) 0.81
Wild-Type KRAS and BRAF Could Predict Response to Cetuximab in Chinese Colorectal Cancer Patients. Chin J Cancer Res (2011) 0.81
p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer. Med Oncol (2014) 0.81
Genetic polymorphisms are associated with variations in warfarin maintenance dose in Han Chinese patients with venous thromboembolism. Pharmacogenomics (2012) 0.81
Axitinib alone or in combination with chemotherapeutic drugs exerts potent antitumor activity against human gastric cancer cells in vitro and in vivo. J Cancer Res Clin Oncol (2014) 0.81
[Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma: analyses of 966 cases]. Zhonghua Bing Li Xue Za Zhi (2012) 0.81
Association between CHFR methylation and chemosensitivity of paclitaxel in advanced gastric cancer. Med Oncol (2014) 0.81
Effect of Qing'e formula on circulating sclerostin levels in patients with postmenopausal osteoporosis. J Huazhong Univ Sci Technolog Med Sci (2015) 0.80
Serum 25-hydroxyvitamin D levels in Chinese children with autism spectrum disorders. Neuroreport (2014) 0.80
Up-regulating arginase contributes to amelioration of chilling stress and the antioxidant system in cherry tomato fruits. J Sci Food Agric (2010) 0.80
Defined media optimization for in vitro culture of bovine somatic cell nuclear transfer (SCNT) embryos. Theriogenology (2012) 0.80
Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial for gastric cancer prevention. World J Gastroenterol (2008) 0.80
Evidence for a left-over-right inhibitory mechanism during figural creative thinking in healthy nonartists. Hum Brain Mapp (2012) 0.80
Detection of gastric carcinoma-associated MG7-Ag by serum immuno-PCR assay in a high-risk Chinese population, with implication for screening. Int J Cancer (2010) 0.80
The assessment of clinicopathological features, therapy pattern and survival benefit of 162 gastric cancers with liver metastases. Hepatogastroenterology (2013) 0.80
Ethylene and cold participate in the regulation of LeCBF1 gene expression in postharvest tomato fruits. FEBS Lett (2009) 0.80
[Determination of six mineral elements in roots, stems, leaves, flowers and seeds of Scutellaria baicalensis by FAAS]. Guang Pu Xue Yu Guang Pu Fen Xi (2009) 0.79
[Three-dimensional spiral CT in advanced gastric cancer]. Zhonghua Zhong Liu Za Zhi (2004) 0.79
Transcatheter arterial chemoembolization for gastrointestinal stromal tumors with liver metastases. World J Gastroenterol (2012) 0.79
Prognostic role of circulating tumor cells in patients with pancreatic cancer: a meta-analysis. Asian Pac J Cancer Prev (2014) 0.79
Effects of Salivae Miltiorrhizae Liguspyragine Hydrochloride and Glucose Injection on the levels of main platelet thrombin receptors in chronic haemodialysis patients. Chin J Integr Med (2011) 0.79
Olig1 and ID4 interactions in living cells visualized by bimolecular fluorescence complementation technique. Mol Biol Rep (2010) 0.79
A statistical design for testing apomictic diversification through linkage analysis. Brief Bioinform (2012) 0.79
Rapid inactivation of chloroplastic ascorbate peroxidase is responsible for oxidative modification to Rubisco in tomato (Lycopersicon esculentum) under cadmium stress. J Integr Plant Biol (2008) 0.79
PI3K/AKT/mTOR pathway is activated after imatinib secondary resistance in gastrointestinal stromal tumors (GISTs). Med Oncol (2015) 0.79
Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy. Biochim Biophys Acta (2013) 0.79
[Comparative study on selenium and amino acids content in leaves of planted and wild Scutellaria baicalensis]. Guang Pu Xue Yu Guang Pu Fen Xi (2009) 0.79