Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa.

PubWeight™: 1.21‹?› | Rank: Top 10%

🔗 View Article (PMID 20942647)

Published in J Infect Dis on October 13, 2010

Authors

Gloria Herrmann1, Liang Yang, Hong Wu, Zhijun Song, Hengzhuang Wang, Niels Høiby, Martina Ulrich, Søren Molin, Joachim Riethmüller, Gerd Döring

Author Affiliations

1: Institute of Medical Microbiology and Hygiene, Universitätsklinikum, University of Tübingen, Tübingen, Germany.

Articles citing this

Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov (2013) 1.82

Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med (2011) 1.49

Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One (2011) 1.31

Strategies for combating bacterial biofilm infections. Int J Oral Sci (2015) 1.17

In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection. Antimicrob Agents Chemother (2012) 1.06

Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms. PLoS One (2013) 1.02

In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells. J Antimicrob Chemother (2012) 0.97

High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2012) 0.95

Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment. Antimicrob Agents Chemother (2011) 0.90

Management of refractory Pseudomonas aeruginosa infection in cystic fibrosis. Infect Drug Resist (2011) 0.90

Antimicrobial peptide GL13K is effective in reducing biofilms of Pseudomonas aeruginosa. Antimicrob Agents Chemother (2013) 0.90

C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth. Sci Rep (2015) 0.88

The MerR-like regulator BrlR impairs Pseudomonas aeruginosa biofilm tolerance to colistin by repressing PhoPQ. J Bacteriol (2013) 0.83

Antibiofilm Peptides: Potential as Broad-Spectrum Agents. J Bacteriol (2016) 0.83

Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm. PLoS One (2014) 0.82

Activities of tobramycin and polymyxin E against Pseudomonas aeruginosa biofilm-coated medical grade endotracheal tubes. Antimicrob Agents Chemother (2013) 0.80

Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms. BMC Microbiol (2015) 0.79

Immune mediators of sea-cucumber Holothuria tubulosa (Echinodermata) as source of novel antimicrobial and anti-staphylococcal biofilm agents. AMB Express (2013) 0.78

Ciprofloxacin DPI: a randomised, placebo-controlled, phase IIb efficacy and safety study on cystic fibrosis. BMJ Open Respir Res (2015) 0.78

Autoinducer-2 regulates Pseudomonas aeruginosa PAO1 biofilm formation and virulence production in a dose-dependent manner. BMC Microbiol (2015) 0.77

Evidence of inhaled tobramycin in non-cystic fibrosis bronchiectasis. Open Respir Med J (2015) 0.77

In Vivo Efficacy of Antimicrobials against Biofilm-Producing Pseudomonas aeruginosa. Antimicrob Agents Chemother (2015) 0.76

Colistimethate sodium for the treatment of chronic pulmonary infection in cystic fibrosis: an evidence-based review of its place in therapy. Core Evid (2014) 0.76

A case of failed eradication of cystic fibrosis-related sinus colonisation by Pseudomonas aeruginosa. BMC Pulm Med (2015) 0.75

Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria. Infect Dis Ther (2015) 0.75

Mitigation of Biofilm Formation on Corrugated Cardboard Fresh Produce Packaging Surfaces Using a Novel Thiazolidinedione Derivative Integrated in Acrylic Emulsion Polymers. Front Microbiol (2016) 0.75

Control of Biofilm Formation: Antibiotics and Beyond. Appl Environ Microbiol (2016) 0.75

Synergistic combinations of polymyxins. Int J Antimicrob Agents (2016) 0.75

Individual and Combined Effects of Engineered Peptides and Antibiotics on Pseudomonas aeruginosa Biofilms. Pharmaceuticals (Basel) (2017) 0.75

In-vitro and in-vivo efficacy of LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm. Antimicrob Agents Chemother (2017) 0.75

Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed? Eur Arch Otorhinolaryngol (2014) 0.75

Articles by these authors

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature (2006) 11.86

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell (2003) 8.11

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature (2006) 7.35

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11

Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell (2007) 6.52

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest (2002) 6.35

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78

Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants. Mol Microbiol (2003) 5.31

Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents (2010) 5.18

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell (2003) 5.13

Cystic fibrosis. Lancet (2003) 5.00

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell (2003) 4.96

A randomized trial comparing radiofrequency ablation and surgical resection for HCC conforming to the Milan criteria. Ann Surg (2010) 4.75

The Arabidopsis lyrata genome sequence and the basis of rapid genome size change. Nat Genet (2011) 4.65

A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol Microbiol (2006) 4.49

Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell (2011) 4.43

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell (2011) 4.41

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis (2002) 4.23

PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet (2007) 4.09

Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res (2008) 3.99

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell (2009) 3.78

Complex Loci in human and mouse genomes. PLoS Genet (2006) 3.74

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature (2011) 3.63

Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell (2011) 3.56

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41

Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell (2010) 3.41

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A (2004) 3.40

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (2002) 3.37

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol (2008) 3.36

Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc Natl Acad Sci U S A (2006) 3.34

Multiple sensors control reciprocal expression of Pseudomonas aeruginosa regulatory RNA and virulence genes. Proc Natl Acad Sci U S A (2005) 3.31

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell (2012) 3.26

Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell (2005) 3.15

OXA-type carbapenemases. J Antimicrob Chemother (2006) 3.15

In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05

Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms. Mol Microbiol (2003) 3.05

Evolution of species interactions in a biofilm community. Nature (2007) 3.01

Cutaneous metastases from genitourinary malignancies. Urology (2004) 2.97

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proc Natl Acad Sci U S A (2005) 2.93

Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis. Microbiology (2007) 2.92

Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression. Mol Microbiol (2004) 2.86

Development and maturation of Escherichia coli K-12 biofilms. Mol Microbiol (2003) 2.86

Evolutionary dynamics of bacteria in a human host environment. Proc Natl Acad Sci U S A (2011) 2.75

Class A carbapenemases. J Antimicrob Chemother (2007) 2.72

The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. J Immunol (2009) 2.68

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc Natl Acad Sci U S A (2002) 2.60

Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus. J Cyst Fibros (2009) 2.59

Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen (2008) 2.58

Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr Pulmonol (2009) 2.53

PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat Immunol (2004) 2.52

Mini-Tn7 transposons for site-specific tagging of bacteria with fluorescent proteins. Environ Microbiol (2004) 2.52

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective. Nat Rev Microbiol (2012) 2.50

Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model. Cancer Res (2009) 2.49

A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression. Cancer Cell (2008) 2.48

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Nature (2008) 2.47

Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res (2012) 2.45

Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. Cancer Cell (2007) 2.43

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. Development (2002) 2.42

Increased expression of stem cell markers in malignant melanoma. Mod Pathol (2006) 2.39

PTENless means more. Dev Biol (2004) 2.31

NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell (2006) 2.29

Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol (2008) 2.27

First case of E anophelis outbreak in an intensive-care unit. Lancet (2013) 2.26

Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. J Clin Invest (2007) 2.26

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (2005) 2.24

Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group Study. Clin Cancer Res (2005) 2.22

Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Appl Environ Microbiol (2002) 2.19

Retracted CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med (2010) 2.17

Stratified growth in Pseudomonas aeruginosa biofilms. Appl Environ Microbiol (2004) 2.16

Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. Cancer Cell (2007) 2.14

Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence. Am J Respir Crit Care Med (2009) 2.08

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. J Biol Chem (2008) 2.07

PTEN dosage is essential for neurofibroma development and malignant transformation. Proc Natl Acad Sci U S A (2009) 2.07

Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology (2009) 2.06

Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nat Immunol (2003) 2.05

Murine cell lines derived from Pten null prostate cancer show the critical role of PTEN in hormone refractory prostate cancer development. Cancer Res (2007) 2.04

A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery. J Neurosci (2006) 2.04

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest (2006) 2.03

Hepatocellular carcinoma: stiffness value and ratio to discriminate malignant from benign focal liver lesions. Radiology (2015) 2.03

Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production. Antimicrob Agents Chemother (2004) 1.99

Occurrence of hypermutable Pseudomonas aeruginosa in cystic fibrosis patients is associated with the oxidative stress caused by chronic lung inflammation. Antimicrob Agents Chemother (2005) 1.94

A detrimental mitochondrial-nuclear interaction causes cytoplasmic male sterility in rice. Nat Genet (2013) 1.92

Volatile metabolites from actinomycetes. J Agric Food Chem (2002) 1.91

Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. J Biol Chem (2005) 1.89

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. Proc Natl Acad Sci U S A (2012) 1.88

The clinical impact of bacterial biofilms. Int J Oral Sci (2011) 1.88

Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology (2007) 1.88

The genomics of selection in dogs and the parallel evolution between dogs and humans. Nat Commun (2013) 1.86