Published in J Neurosci on October 13, 2010
Differential function of Gγ13 in rod bipolar and ON cone bipolar cells. J Physiol (2015) 0.93
Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors. J Biol Chem (2011) 0.92
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain. J Biol Chem (2015) 0.86
Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors. J Neurosci (2011) 0.85
R9AP targeting to rod outer segments is independent of rhodopsin and is guided by the SNARE homology domain. Mol Biol Cell (2014) 0.81
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RGS expression rate-limits recovery of rod photoresponses. Neuron (2006) 3.48
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RGS9 modulates dopamine signaling in the basal ganglia. Neuron (2003) 2.61
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. Nature (2004) 2.48
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Identification of an outer segment targeting signal in the COOH terminus of rhodopsin using transgenic Xenopus laevis. J Cell Biol (2000) 2.14
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Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4). Proc Natl Acad Sci U S A (2005) 1.99
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. J Biol Chem (2005) 1.93
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity. J Biol Chem (2003) 1.91
Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice. Neuron (1991) 1.88
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R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. Proc Natl Acad Sci U S A (2002) 1.75
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. J Neurosci (2005) 1.74
Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. J Cell Biol (2005) 1.68
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem (2003) 1.60
The C terminus of peripherin/rds participates in rod outer segment targeting and alignment of disk incisures. Mol Biol Cell (2004) 1.58
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The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J Neurosci (2003) 1.51
A role for rhodopsin in a signal transduction cascade that regulates membrane trafficking and photoreceptor polarity. Vision Res (2006) 1.49
Signaling properties of a short-wave cone visual pigment and its role in phototransduction. J Neurosci (2007) 1.49
A model for transport of membrane-associated phototransduction polypeptides in rod and cone photoreceptor inner segments. Vision Res (2007) 1.44
Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice. J Neurosci (2003) 1.38
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. J Neurosci (2007) 1.35
Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding. Biochem Pharmacol (2001) 1.32
The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors. J Cell Biol (2008) 1.32
R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling. Trends Pharmacol Sci (2008) 1.30
Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia. Science (2009) 1.29
R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. J Biol Chem (2006) 1.29
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. J Neurosci (2008) 1.26
Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. J Biol Chem (2003) 1.20
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Mol Cell Neurosci (2007) 1.19
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP. J Biol Chem (2006) 1.18
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity. J Biol Chem (2002) 1.14
Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain. Neuroscience (2007) 1.13
RGS9 concentration matters in rod phototransduction. Biophys J (2009) 1.12
Motor coordination deficits in mice lacking RGS9. Brain Res (2007) 1.11
An outer segment localization signal at the C terminus of the photoreceptor-specific retinol dehydrogenase. J Neurosci (2004) 1.11
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Light-dependent compartmentalization of transducin in rod photoreceptors. Mol Neurobiol (2008) 1.08
RGS9-2: probing an intracellular modulator of behavior as a drug target. Trends Pharmacol Sci (2009) 1.08
RGS9-G beta 5 substrate selectivity in photoreceptors. Opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complex. J Biol Chem (2001) 1.04
Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous system. Mol Cell Neurosci (2003) 1.01
Kinetic mechanism of RGS9-1 potentiation by R9AP. Biochemistry (2006) 0.99
Enzymology of GTPase acceleration in phototransduction. Methods Enzymol (2000) 0.95
Functional comparison of RGS9 splice isoforms in a living cell. Proc Natl Acad Sci U S A (2008) 0.94
Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling. J Biol Chem (2009) 0.93
Biology and functions of the RGS9 isoforms. Prog Mol Biol Transl Sci (2009) 0.93
Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein. J Neurochem (2010) 0.88
RGS expression level precisely regulates the duration of rod photoresponses. Neuron (2006) 0.86
Kinetic approaches to study the function of RGS9 isoforms. Methods Enzymol (2004) 0.83
Mutations in GNAL cause primary torsion dystonia. Nat Genet (2012) 3.66
RGS expression rate-limits recovery of rod photoresponses. Neuron (2006) 3.48
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. Nature (2004) 2.48
The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling. Cell Biochem Biophys (2009) 1.79
The cone-specific visual cycle. Prog Retin Eye Res (2010) 1.78
Noncanonical autophagy promotes the visual cycle. Cell (2013) 1.74
Intra-retinal visual cycle required for rapid and complete cone dark adaptation. Nat Neurosci (2009) 1.70
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem (2003) 1.60
An alternative pathway mediates the mouse and human cone visual cycle. Curr Biol (2009) 1.56
Visual cycle: Dependence of retinol production and removal on photoproduct decay and cell morphology. J Gen Physiol (2006) 1.54
The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J Neurosci (2003) 1.51
Signaling properties of a short-wave cone visual pigment and its role in phototransduction. J Neurosci (2007) 1.49
Establishment of clonal cell lines of taste buds from a p53(-/-) mouse tongue. In Vitro Cell Dev Biol Anim (2011) 1.40
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein. J Neurosci (2011) 1.33
The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2. J Biol Chem (2006) 1.31
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. J Neurosci (2007) 1.28
Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death. J Neurosci (2008) 1.28
Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons. Proc Natl Acad Sci U S A (2012) 1.26
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. J Neurosci (2008) 1.26
Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling. Nat Neurosci (2010) 1.22
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Mol Cell Neurosci (2007) 1.19
RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate. Circ Res (2010) 1.18
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP. J Biol Chem (2006) 1.18
TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner. J Neurosci (2011) 1.17
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity. J Biol Chem (2002) 1.14
Role of guanylyl cyclase modulation in mouse cone phototransduction. J Neurosci (2011) 1.13
Age-related deterioration of rod vision in mice. J Neurosci (2010) 1.10
Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle. J Neurosci (2011) 1.10
GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J Cell Biol (2012) 1.06
G-protein betagamma-complex is crucial for efficient signal amplification in vision. J Neurosci (2011) 1.05
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity. J Neurosci (2010) 1.04
Functional interchangeability of rod and cone transducin alpha-subunits. Proc Natl Acad Sci U S A (2009) 1.02
Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors. J Biol Chem (2011) 0.99
Kinetic mechanism of RGS9-1 potentiation by R9AP. Biochemistry (2006) 0.99
Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits. Mol Cell Biol (2009) 0.99
Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci (2009) 0.97
Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells. J Biol Chem (2013) 0.97
Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival. Mol Cell Proteomics (2010) 0.96
Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability. PLoS One (2013) 0.95
R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine. Neuropsychopharmacology (2009) 0.95
Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest (2012) 0.95
The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum. Sci Signal (2012) 0.95
Reprogramming of adult rod photoreceptors prevents retinal degeneration. Proc Natl Acad Sci U S A (2013) 0.94
Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors. Invest Ophthalmol Vis Sci (2011) 0.94
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis. Hum Mol Genet (2013) 0.93
Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling. J Biol Chem (2009) 0.93
Anti-idiotypic antibody mimics proteolytic function of parent antigen. Biochemistry (2007) 0.92
Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors. J Biol Chem (2011) 0.92
Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems. Psychopharmacology (Berl) (2011) 0.92
CRALBP supports the mammalian retinal visual cycle and cone vision. J Clin Invest (2015) 0.90
A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins. J Biol Chem (2010) 0.90
Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein. J Neurochem (2010) 0.88
GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci (2014) 0.88
Control of striatal signaling by g protein regulators. Front Neuroanat (2011) 0.87
Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction. Bioconjug Chem (2005) 0.87
Monitoring G Protein Activation in Cells with BRET. Methods Mol Biol (2015) 0.86
Single-cell suction recordings from mouse cone photoreceptors. J Vis Exp (2010) 0.86
The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit. J Biol Chem (2006) 0.86
Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons. Hippocampus (2013) 0.85
Proteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysis. J Proteome Res (2010) 0.85
Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors. J Neurosci (2013) 0.85
Transretinal ERG recordings from mouse retina: rod and cone photoresponses. J Vis Exp (2012) 0.85
Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci (2013) 0.85
RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. Elife (2014) 0.85
R7BP modulates opiate analgesia and tolerance but not withdrawal. Neuropsychopharmacology (2011) 0.84
Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability. Invest Ophthalmol Vis Sci (2009) 0.84
Substrate recognition of anthrax lethal factor examined by combinatorial and pre-steady-state kinetic approaches. J Biol Chem (2009) 0.82
Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse. J Neurosci (2013) 0.82
R9AP overexpression alters phototransduction kinetics in iCre75 mice. Invest Ophthalmol Vis Sci (2014) 0.82
The 9-methyl group of retinal is essential for rapid Meta II decay and phototransduction quenching in red cones. J Gen Physiol (2009) 0.81
Purification of filamentous bacteriophage for phage display using size-exclusion chromatography. Biotechniques (2005) 0.80
Distribution of regulator of G protein signaling 8 (RGS8) protein in the cerebellum. Cerebellum (2003) 0.78
RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate. J Biol Chem (2013) 0.77
Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex. Invest Ophthalmol Vis Sci (2012) 0.76