Published in J Neurosci on August 10, 2011
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Mutations in TRPM1 are a common cause of complete congenital stationary night blindness. Am J Hum Genet (2009) 1.92
LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature (2010) 1.89
TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal (2009) 1.75
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Mutations in GRM6 cause autosomal recessive congenital stationary night blindness with a distinctive scotopic 15-Hz flicker electroretinogram. Invest Ophthalmol Vis Sci (2005) 1.57
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Nyctalopin expression in retinal bipolar cells restores visual function in a mouse model of complete X-linked congenital stationary night blindness. J Neurophysiol (2007) 1.46
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Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
TRPM1: the endpoint of the mGluR6 signal transduction cascade in retinal ON-bipolar cells. Bioessays (2010) 1.37
TRPM1 mutations are associated with the complete form of congenital stationary night blindness. Mol Vis (2010) 1.37
Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses. J Physiol (2008) 1.36
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. J Neurosci (2008) 1.26
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Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions. J Biol Chem (2011) 1.04
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Optimization of single-photon response transmission at the rod-to-rod bipolar synapse. Physiology (Bethesda) (2007) 1.02
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Transmission of scotopic signals from the rod to rod-bipolar cell in the mammalian retina. Vision Res (2004) 0.93
Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling. J Biol Chem (2009) 0.93
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RGS expression level precisely regulates the duration of rod photoresponses. Neuron (2006) 0.86
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A common NYX mutation in Flemish patients with X linked CSNB. Br J Ophthalmol (2008) 0.84
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Mutations in GNAL cause primary torsion dystonia. Nat Genet (2012) 3.66
RGS expression rate-limits recovery of rod photoresponses. Neuron (2006) 3.48
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. Nature (2004) 2.48
The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling. Cell Biochem Biophys (2009) 1.79
Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse. J Biol Chem (2003) 1.60
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2. J Biol Chem (2006) 1.31
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. J Neurosci (2007) 1.28
Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death. J Neurosci (2008) 1.28
Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons. Proc Natl Acad Sci U S A (2012) 1.26
Targeting of RGS7/Gbeta5 to the dendritic tips of ON-bipolar cells is independent of its association with membrane anchor R7BP. J Neurosci (2008) 1.26
Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling. Nat Neurosci (2010) 1.22
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Mol Cell Neurosci (2007) 1.19
RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate. Circ Res (2010) 1.18
Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP. J Biol Chem (2006) 1.18
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity. J Biol Chem (2002) 1.14
GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J Cell Biol (2012) 1.06
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity. J Neurosci (2010) 1.04
Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors. J Biol Chem (2011) 0.99
Kinetic mechanism of RGS9-1 potentiation by R9AP. Biochemistry (2006) 0.99
Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits. Mol Cell Biol (2009) 0.99
Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells. J Biol Chem (2013) 0.97
Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival. Mol Cell Proteomics (2010) 0.96
Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability. PLoS One (2013) 0.95
R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine. Neuropsychopharmacology (2009) 0.95
The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum. Sci Signal (2012) 0.95
Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling. J Biol Chem (2009) 0.93
Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems. Psychopharmacology (Berl) (2011) 0.92
Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors. J Biol Chem (2011) 0.92
A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins. J Biol Chem (2010) 0.90
Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein. J Neurochem (2010) 0.88
GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci (2014) 0.88
Control of striatal signaling by g protein regulators. Front Neuroanat (2011) 0.87
Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons. J Neurosci (2010) 0.87
Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction. Bioconjug Chem (2005) 0.87
Monitoring G Protein Activation in Cells with BRET. Methods Mol Biol (2015) 0.86
The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit. J Biol Chem (2006) 0.86
Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons. Hippocampus (2013) 0.85
Proteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysis. J Proteome Res (2010) 0.85
RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. Elife (2014) 0.85
Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci (2013) 0.85
R7BP modulates opiate analgesia and tolerance but not withdrawal. Neuropsychopharmacology (2011) 0.84
RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate. J Biol Chem (2013) 0.77