Published in Neurol Sci on October 16, 2010
Effects of the BDNF Val66Met polymorphism on white matter microstructure in healthy adults. Neuropsychopharmacology (2012) 0.90
Association study of gene polymorphisms and depression with abnormal humor in traditional Uighur medicine. BMC Complement Altern Med (2013) 0.78
The BDNF Val66Met polymorphism has opposite effects on memory circuits of multiple sclerosis patients and controls. PLoS One (2013) 0.75
Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology (1983) 40.64
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell (2003) 12.50
Axonal transection in the lesions of multiple sclerosis. N Engl J Med (1998) 12.21
Neurotrophins as synaptic modulators. Nat Rev Neurosci (2001) 7.08
Multiple sclerosis--the plaque and its pathogenesis. N Engl J Med (2006) 6.60
Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain (2005) 5.29
Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci (2003) 5.11
The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci (2004) 4.84
BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol (2005) 4.34
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol (2001) 4.06
Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci (2004) 3.47
Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients. Ann Neurol (2006) 2.93
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics (2007) 2.89
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med (1999) 2.84
Cortical lesions in multiple sclerosis. Brain (1999) 2.83
BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biol Psychiatry (2006) 2.79
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem (2002) 2.79
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J (1990) 2.77
Environmental factors and multiple sclerosis. Lancet Neurol (2008) 2.66
The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol (2006) 2.47
Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Arch Gen Psychiatry (2007) 2.05
Evidence of early cortical atrophy in MS: relevance to white matter changes and disability. Neurology (2003) 1.94
Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability. J Neurol Sci (2007) 1.61
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach. Magn Reson Med (1997) 1.60
Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers. Arch Gen Psychiatry (2006) 1.59
Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology (2001) 1.53
Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly. Genes Brain Behav (2007) 1.47
BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain (2002) 1.33
Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia. Am J Psychiatry (2007) 1.33
Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males. Brain Res Mol Brain Res (2005) 1.21
The pathology of MS: new insights and potential clinical applications. Neurologist (2007) 1.19
The Val66Met polymorphism of the brain-derived neurotrophic factor gene affects age-related brain morphology. Neurosci Lett (2006) 1.18
Cutting edge: clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors. J Immunol (1999) 1.16
Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. J Neurosci Res (2001) 1.16
Cellular sources of enhanced brain-derived neurotrophic factor production in a mouse model of allergic inflammation. Am J Respir Cell Mol Biol (1999) 1.14
Evidence for pathogenic heterogeneity in multiple sclerosis. Ann Neurol (2004) 1.10
Brain atrophy and lesion load in a large population of patients with multiple sclerosis. Neurology (2005) 1.10
Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis. J Magn Reson Imaging (2000) 1.05
Measurement of whole-brain atrophy in multiple sclerosis. J Neuroimaging (2004) 0.99
Distribution and localization of pro-brain-derived neurotrophic factor-like immunoreactivity in the peripheral and central nervous system of the adult rat. J Neurochem (2004) 0.98
Immune cell BDNF secretion is associated with white matter volume in multiple sclerosis. J Neuroimmunol (2007) 0.98
Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor. Hum Mol Genet (2007) 0.93
Effect of BDNF val66met polymorphism on age-related amygdala volume changes in healthy subjects. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.93
Genes for multiple sclerosis. Lancet (2008) 0.91
Brain atrophy in relapsing-remitting multiple sclerosis: fractional volumetric analysis of gray matter and white matter. Radiology (2001) 0.91
Impact of the brain-derived neurotrophic factor Val66Met polymorphism on levels of hippocampal N-acetyl-aspartate assessed by magnetic resonance spectroscopic imaging at 3 Tesla. Biol Psychiatry (2008) 0.90
MR correlates of cerebral atrophy in patients with multiple sclerosis. J Neurol (2002) 0.90
Environment-gene interaction in multiple sclerosis: human herpesvirus 6 and MHC2TA. Hum Immunol (2007) 0.89
Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons. Neurosci Lett (2008) 0.85
In vivo effects of neurotrophin-3 during sensory neurogenesis. Development (1996) 0.85
Brain tissue volume changes in relapsing-remitting multiple sclerosis: correlation with lesion load. Neuroimage (2003) 0.83
A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis. Brain Res (2008) 0.82
Investigating the role of brain-derived neurotrophic factor in relapsing-remitting multiple sclerosis. Genes Brain Behav (2007) 0.79
Neuropsychological assessment, quantitative MRI and ApoE gene polymorphisms in a series of MS patients treated with IFN beta-1b. J Neurol Sci (2006) 0.78
Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant. Biol Psychiatry (2009) 0.78
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation. Magn Reson Med (1998) 0.76
The BDNF-Val66Met polymorphism: implications for susceptibility to multiple sclerosis and severity of disease. J Neuroimmunol (2005) 0.76
No association of the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) to multiple sclerosis. Neurosci Lett (2005) 0.76
Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study. Mult Scler (2008) 0.76
The fission yeast cdc18+ gene product couples S phase to START and mitosis. Cell (1993) 6.25
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer (2001) 5.36
Founder mutations in BRCA1 and BRCA2 genes. Ann Oncol (2007) 3.26
Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases. J Viral Hepat (2007) 2.87
Intake of macronutrients and risk of breast cancer. Lancet (1996) 2.81
High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. Am J Pathol (1999) 2.80
A centralised telephone service for tobacco cessation: the California experience. Tob Control (2000) 2.55
The many roles of an RNA editor. Nat Rev Genet (2001) 2.55
Neurophysiological correlates of age-related changes in human motor function. Neurology (2002) 2.52
Reconstitution of simian virus 40 DNA replication with purified proteins. Proc Natl Acad Sci U S A (1990) 2.32
Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis. Am J Pathol (2001) 2.13
Overexpression of folate binding protein in ovarian cancers. Int J Cancer (1997) 2.13
Different patterns of lung recruitment maneuvers in primary acute respiratory distress syndrome: effects on oxygenation and central hemodynamics. Minerva Anestesiol (2010) 2.12
Serum lactate dehydrogenase as early marker of posterior reversible encephalopathy syndrome: keep your eyes open. Anaesth Intensive Care (2012) 2.01
HPV in oral squamous cell carcinoma vs head and neck squamous cell carcinoma biopsies: a meta-analysis (1988-2007). Ann Oncol (2008) 1.99
Follow-up strategies for women treated for early breast cancer. Cochrane Database Syst Rev (2005) 1.98
Predictors of delayed gastric emptying in diabetes. Diabetes Care (2001) 1.98
Pattern of cancer risk in persons with AIDS in Italy in the HAART era. Br J Cancer (2009) 1.95
Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. Cancer Res (1993) 1.88
High speed 1H spectroscopic imaging in human brain by echo planar spatial-spectral encoding. Magn Reson Med (1995) 1.87
Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut (2005) 1.84
Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine. Biochem Pharmacol (1982) 1.83
Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype. Ann Oncol (2002) 1.74
Tracheostomy in Intensive Care Unit: a national survey in Italy. Minerva Anestesiol (2012) 1.73
On the spin trapping and ESR detection of oxygen-derived radicals generated inside cells. Proc Natl Acad Sci U S A (1986) 1.72
Biologically active metal-independent superoxide dismutase mimics. Biochemistry (1990) 1.72
Factors affecting in-hospital heat-related mortality: a multi-city case-crossover analysis. J Epidemiol Community Health (2008) 1.70
Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis. J Clin Oncol (2003) 1.69
Intake of selected micronutrients and risk of colorectal cancer. Int J Cancer (1997) 1.68
The effects of hydroxyethyl starch solution in critically ill patients. Minerva Anestesiol (2006) 1.67
Chronic effects of therapeutic irradiation for localized prostatic carcinoma on anorectal function. Int J Radiat Oncol Biol Phys (2000) 1.64
Factors affecting splanchnic haemodynamics in Crohn's disease: a prospective controlled study using Doppler ultrasound. Gut (1998) 1.64
Systematic pelvic and para-aortic lymphadenectomy during cytoreductive surgery in advanced ovarian cancer: potential benefit on survival. Gynecol Oncol (1995) 1.60
Bromodeoxyuridine in tumors and chromosomes detected with a monoclonal antibody. J Clin Invest (1983) 1.59
Do nitroxide antioxidants act as scavengers of O2-. or as SOD mimics? J Biol Chem (1996) 1.59
Intrapleural photodynamic therapy: results of a phase I trial. Ann Surg Oncol (1994) 1.56
Petrous bone cholesteatoma. Skull Base Surg (1993) 1.55
The impact of the summer 2003 heat waves on mortality in four Italian cities. Euro Surveill (2005) 1.55
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide. Proc Natl Acad Sci U S A (1992) 1.54
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol. Arch Biochem Biophys (1991) 1.53
Systematic review: green tea and gastrointestinal cancer risk. Aliment Pharmacol Ther (2004) 1.49
Syphilitic aortitis. Catheter Cardiovasc Interv (2001) 1.49
The Frontal Assessment Battery (FAB): normative values in an Italian population sample. Neurol Sci (2005) 1.48
Informed consent for tracheostomy procedures in Intensive Care Unit: an Italian national survey. Minerva Anestesiol (2013) 1.48
Thyrotropin receptor mutations and thyroid hyperfunctioning adenomas ten years after their first discovery: unresolved questions. Thyroid (2003) 1.46
A novel Angiogenin gene mutation in a sporadic patient with amyotrophic lateral sclerosis from southern Italy. Neuromuscul Disord (2007) 1.45
Telephone counseling as adjuvant treatment for nicotine replacement therapy in a "real-world" setting. Prev Med (2000) 1.45
Searches for Lepton flavor violation in the decays tau{+/-}-->e{+/-}gamma and tau{+/-}-->mu{+/-}gamma. Phys Rev Lett (2010) 1.44
Left atrial thrombus and spontaneous echo-contrast in nonanticoagulated mitral stenosis. A transesophageal echocardiographic study. Chest (1993) 1.43
Evidence for neuroaxonal injury in patients with proteolipid protein gene mutations. Neurology (2001) 1.42
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion. Oncogene (2008) 1.42
Intra-abdominal hypertension is not reliable as an early predictor of mortality in the intensive care unit. Minerva Anestesiol (2007) 1.41
[Anterior chamber migration of intravitreal dexamethasone implant (Ozurdex®) in pseudophakic eyes: report of three cases]. J Fr Ophtalmol (2013) 1.40
Antithrombotic drugs in secondary stroke prevention among a community dwelling older population. J Neurol Neurosurg Psychiatry (2003) 1.40
Facial nerve neuromas: diagnosis and management. Am J Otol (1995) 1.40
Baseline and CRH-stimulated ACTH and cortisol levels after administration of the peroxisome proliferator-activated receptor-gamma ligand, rosiglitazone, in Cushing's disease. J Endocrinol Invest (2004) 1.39
Derecruitment of the lung induced by stepwise lowering of positive end-expiratory pressure in patients with adult respiratory distress syndrome. Eur J Anaesthesiol (2003) 1.39
Prolonging proton pump inhibitor-based anti-Helicobacter pylori treatment from one to two weeks in duodenal ulcer: is it worthwhile? Dig Liver Dis (2000) 1.39
Navigator® and SmartPilot® View are helpful in guiding anesthesia and reducing anesthetic drug dosing. Minerva Anestesiol (2015) 1.38
Interferon therapy in HCV-positive mixed cryoglobulinaemia: viral and host factors contributing to efficacy of the therapy. Ital J Gastroenterol Hepatol (1997) 1.38
Leukocyte alkaline phosphatase (LAP). A useful marker of zinc status in beta-thalassemic patients. Am J Pediatr Hematol Oncol (1987) 1.38
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates. Chemical aspects involved in the balance between oxidative and nitrosative stress. J Biol Chem (1997) 1.37
Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer. Int J Cancer (1998) 1.36
Vogt-Koyanagi-Harada syndrome. Autoimmun Rev (2013) 1.35
Breast cancer genome-wide association studies: there is strength in numbers. Oncogene (2011) 1.34
Epidemiological trend of human leptospirosis in Italy between 1994 and 1996. Eur J Epidemiol (2000) 1.34
Patterns of genomic instability in gastric cancer: clinical implications and perspectives. Ann Oncol (2006) 1.33
Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism. J Biol Chem (1996) 1.33
Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia (2002) 1.33
The present and the future of neuroimaging in amyotrophic lateral sclerosis. AJNR Am J Neuroradiol (2010) 1.30
Myringoplasty in children: factors influencing surgical outcome. Otolaryngol Head Neck Surg (1998) 1.29
Ras family genes: an interesting link between cell cycle and cancer. J Cell Physiol (2002) 1.29
Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance? Ann Oncol (2012) 1.28
Large-scale spatial distribution of virioplankton in the Adriatic Sea: testing the trophic state control hypothesis. Appl Environ Microbiol (2003) 1.28
Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes. Neurology (2010) 1.27
Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1. Mol Psychiatry (2008) 1.27
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs. Cancer Res (1986) 1.27
A novel metal-free low molecular weight superoxide dismutase mimic. J Biol Chem (1988) 1.26
In vivo imaging of a stable paramagnetic probe by pulsed-radiofrequency electron paramagnetic resonance spectroscopy. Magn Reson Med (1997) 1.26
Pain management in frail, community-living elderly patients. Arch Intern Med (2001) 1.26
Carotid vascular abnormalities in primary hyperparathyroidism. J Clin Endocrinol Metab (2009) 1.26
Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis. Int J Cancer (2001) 1.26
Photodynamic therapy. J Clin Oncol (1988) 1.25
'Isolated' pulmonary valve stenosis as part of more widespread cardiovascular disease. Br Heart J (1976) 1.25
Grey matter loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study. Neuroimage (2005) 1.25
Discriminative and predictive power of an informant report in mild cognitive impairment. J Neurol Neurosurg Psychiatry (2006) 1.25
Meal-generated oxidative stress in type 2 diabetic patients. Diabetes Care (1998) 1.24
Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging. Am J Psychiatry (1996) 1.23
Prognostic factors for lymphedema after primary treatment of breast carcinoma. Cancer (2001) 1.21
Impact of in situ chemical oxidation on contaminant mass discharge: linking source-zone and plume-scale characterizations of remediation performance. Environ Sci Technol (2011) 1.21
Prevalence of anxiety disorders comorbidity in bipolar depression, unipolar depression and dysthymia. J Affect Disord (1997) 1.21
Characterizing long-term contaminant mass discharge and the relationship between reductions in discharge and reductions in mass for DNAPL source areas. J Contam Hydrol (2013) 1.21
Initiation of SV40 DNA replication: mechanism and control. Cold Spring Harb Symp Quant Biol (1991) 1.21
Antioxidant defences are reduced during the oral glucose tolerance test in normal and non-insulin-dependent diabetic subjects. Eur J Clin Invest (1998) 1.21