Published in Learn Mem on October 02, 2002
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol (2008) 2.83
The diseasome of physical inactivity--and the role of myokines in muscle--fat cross talk. J Physiol (2009) 2.47
BDNF is essential to promote persistence of long-term memory storage. Proc Natl Acad Sci U S A (2008) 2.16
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. Learn Mem (2004) 1.99
Review: microglia of the aged brain: primed to be activated and resistant to regulation. Neuropathol Appl Neurobiol (2013) 1.82
Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol (2006) 1.77
Brain-derived neurotrophic factor and cocaine addiction. Brain Res (2009) 1.76
The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases. J Biomed Biotechnol (2010) 1.75
Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. Mol Psychiatry (2009) 1.71
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci (2005) 1.68
Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones. J Physiol (2003) 1.67
Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J Neurosci (2003) 1.64
BDNF activates mTOR to regulate GluR1 expression required for memory formation. PLoS One (2009) 1.63
TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation. J Neurosci (2007) 1.56
Leptin promotes rapid dynamic changes in hippocampal dendritic morphology. Mol Cell Neurosci (2007) 1.55
Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS. Front Neuroendocrinol (2006) 1.40
The lighter side of BDNF. Am J Physiol Regul Integr Comp Physiol (2011) 1.38
Role of BDNF and GDNF in drug reward and relapse: a review. Neurosci Biobehav Rev (2009) 1.31
Experimental models of Rett syndrome based on Mecp2 dysfunction. Exp Biol Med (Maywood) (2011) 1.27
BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses. J Physiol (2006) 1.26
Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice. J Neurosci (2012) 1.25
Molecular mechanisms of psychostimulant-induced structural plasticity. Pharmacopsychiatry (2009) 1.25
Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases. Genome Biol (2008) 1.22
Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. Learn Mem (2007) 1.21
Little exercise, big effects: reversing aging and infection-induced memory deficits, and underlying processes. J Neurosci (2011) 1.19
From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders. Neurobiol Learn Mem (2013) 1.19
Foreground contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation. Learn Mem (2006) 1.18
The role of neurotrophins in neurotransmitter release. Neuroscientist (2002) 1.17
Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response. Arch Gen Psychiatry (2009) 1.15
Escalating ethanol intake is associated with altered corticostriatal BDNF expression. J Neurochem (2009) 1.13
Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation. Exp Neurol (2010) 1.12
A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning. Hippocampus (2009) 1.12
Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism. J Neurodev Disord (2009) 1.10
Memory impairments in healthy aging: Role of aging-induced microglial sensitization. Aging Dis (2010) 1.09
Changes in hippocampal function of ovariectomized rats after sequential low doses of estradiol to simulate the preovulatory estrogen surge. Eur J Neurosci (2007) 1.09
BDNF induces calcium elevations associated with IBDNF, a nonselective cationic current mediated by TRPC channels. J Neurophysiol (2007) 1.08
Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology. Proc Natl Acad Sci U S A (2010) 1.07
The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media. J Neurosci Methods (2007) 1.06
Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood? J Biosci (2006) 1.06
Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity. Nat Neurosci (2013) 1.04
miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF. Cell Mol Life Sci (2014) 1.03
β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1. J Biol Chem (2013) 1.03
Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. J Neurosci (2011) 1.03
Transient receptor potential channels as novel effectors of brain-derived neurotrophic factor signaling: potential implications for Rett syndrome. Pharmacol Ther (2006) 1.03
BDNF deregulation in Rett syndrome. Neuropharmacology (2013) 1.02
Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. Am J Drug Alcohol Abuse (2009) 1.02
An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide. Acta Neuropathol (2011) 1.02
Brain derived neurotrophic factor (BDNF) expression is regulated by microRNAs miR-26a and miR-26b allele-specific binding. PLoS One (2011) 1.01
Differential regional expression of brain-derived neurotrophic factor following olfactory fear learning. Learn Mem (2007) 1.01
Low BDNF is associated with cognitive impairment in chronic patients with schizophrenia. Psychopharmacology (Berl) (2012) 0.98
Dendritic spine dysgenesis in Rett syndrome. Front Neuroanat (2014) 0.97
Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3 CA1 connections in the hippocampus. Proc Natl Acad Sci U S A (2007) 0.97
Endogenous BDNF is required for long-term memory formation in the rat parietal cortex. Learn Mem (2005) 0.96
Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus. Neuroscience (2011) 0.96
Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism. Behav Neurosci (2010) 0.96
Intracellular Ca2+ stores and Ca2+ influx are both required for BDNF to rapidly increase quantal vesicular transmitter release. Neural Plast (2012) 0.96
Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus. Neurobiol Aging (2011) 0.94
Brain-derived neurotrophic factor-estrogen interactions in the hippocampal mossy fiber pathway: implications for normal brain function and disease. Neuroscience (2012) 0.94
BDNF-TrkB signaling through Erk1/2 MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids. Mol Psychiatry (2013) 0.94
Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF). Horm Behav (2007) 0.93
Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning. Genes Brain Behav (2012) 0.93
Object-place recognition learning triggers rapid induction of plasticity-related immediate early genes and synaptic proteins in the rat dentate gyrus. Neural Plast (2009) 0.93
Altered balance of proteolytic isoforms of pro-brain-derived neurotrophic factor in autism. J Neuropathol Exp Neurol (2012) 0.92
Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS One (2013) 0.92
Increasing genotype-phenotype model determinism: application to bivariate reading/language traits and epistatic interactions in language-impaired families. Hum Hered (2010) 0.92
Estrogen-growth factor interactions and their contributions to neurological disorders. Headache (2008) 0.91
Impaired spatial working memory and decreased frontal cortex BDNF protein level in dopamine transporter knockout mice. Eur J Pharmacol (2009) 0.91
BDNF modulation of NMDA receptors is activity dependent. J Neurophysiol (2008) 0.91
Acupuncture stimulation alleviates corticosterone-induced impairments of spatial memory and cholinergic neurons in rats. Evid Based Complement Alternat Med (2011) 0.91
Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory. Acta Pharmacol Sin (2009) 0.90
The Effects of Antecedent Exercise on Motor Function Recovery and Brain-derived Neurotrophic Factor Expression after Focal Cerebral Ischemia in Rats. J Phys Ther Sci (2013) 0.90
Acupuncture stimulation improves scopolamine-induced cognitive impairment via activation of cholinergic system and regulation of BDNF and CREB expressions in rats. BMC Complement Altern Med (2014) 0.90
The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease. Aging Dis (2015) 0.90
Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models. Transl Psychiatry (2013) 0.90
Environmental enrichment attenuates hippocampal neuroinflammation and improves cognitive function during influenza infection. Brain Behav Immun (2012) 0.89
Preliminary evidence of cannabinoid effects on brain-derived neurotrophic factor (BDNF) levels in humans. Psychopharmacology (Berl) (2008) 0.89
Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Hum Genet (2012) 0.89
Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor. Neurobiol Learn Mem (2010) 0.89
Aging-related changes in neuroimmune-endocrine function: implications for hippocampal-dependent cognition. Horm Behav (2012) 0.89
BDNF evokes release of endogenous cannabinoids at layer 2/3 inhibitory synapses in the neocortex. J Neurophysiol (2010) 0.88
Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise. Bone (2015) 0.88
Decreased mRNA and Protein Expression of BDNF, NGF, and their Receptors in the Hippocampus from Suicide: An Analysis in Human Postmortem Brain. Clin Med Insights Pathol (2013) 0.88
Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity. Neuropharmacology (2014) 0.87
Divergent roles of p75NTR and Trk receptors in BDNF's effects on dendritic spine density and morphology. Neural Plast (2012) 0.87
LIM kinase 1 (LIMK1) interacts with tropomyosin-related kinase B (TrkB) and Mediates brain-derived neurotrophic factor (BDNF)-induced axonal elongation. J Biol Chem (2012) 0.87
BDNF boosts spike fidelity in chaotic neural oscillations. Biophys J (2004) 0.86
Enriched environment prevents hypobaric hypoxia induced memory impairment and neurodegeneration: role of BDNF/PI3K/GSK3β pathway coupled with CREB activation. PLoS One (2013) 0.86
Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model. J Inherit Metab Dis (2012) 0.85
BDNF enhances dendritic Ca2+ signals evoked by coincident EPSPs and back-propagating action potentials in CA1 pyramidal neurons. Brain Res (2006) 0.85
The BDNF Val66Met polymorphism modulates the generalization of cued fear responses to a novel context. Neuropsychopharmacology (2013) 0.85
Mammary tumors induce select cognitive impairments. Brain Behav Immun (2010) 0.84
Regulation of BDNF expression by cocaine. Yale J Biol Med (2012) 0.84
VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. J Neurosci (2015) 0.84
Serum brain-derived neurotrophic factor (BDNF) levels in attention deficit-hyperactivity disorder (ADHD). Eur Child Adolesc Psychiatry (2013) 0.84
Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability. J Neurochem (2014) 0.83
HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons. Hippocampus (2011) 0.83
Multistage drug effects of ketamine in the treatment of major depression. Eur Arch Psychiatry Clin Neurosci (2014) 0.82
Persistent downregulation of hippocampal CREB mRNA parallels a Y-maze deficit in adolescent rats following semi-chronic amphetamine administration. Br J Pharmacol (2008) 0.82
BDNF transcripts, proBDNF and proNGF, in the cortex and hippocampus throughout the life span of the rat. Age (Dordr) (2012) 0.82
Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci (2001) 11.40
Synaptic plasticity and memory: an evaluation of the hypothesis. Annu Rev Neurosci (2000) 8.20
Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02
Dendritic spine changes associated with hippocampal long-term synaptic plasticity. Nature (1999) 7.72
Neurotrophins as synaptic modulators. Nat Rev Neurosci (2001) 7.08
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell (1996) 6.96
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell (1994) 6.67
Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu Rev Neurosci (2001) 6.36
Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science (1999) 6.08
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron (1996) 5.19
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci (1995) 5.10
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.03
Synaptic modification by correlated activity: Hebb's postulate revisited. Annu Rev Neurosci (2001) 4.60
Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science (1992) 4.58
Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci (2000) 4.55
Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature (1996) 4.41
Essential role for TrkB receptors in hippocampus-mediated learning. Neuron (1999) 4.20
Exercise and brain neurotrophins. Nature (1995) 4.06
Neurotrophins and synaptic plasticity. Annu Rev Neurosci (1999) 4.01
Requirement of a critical period of transcription for induction of a late phase of LTP. Science (1994) 3.85
The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem (2001) 3.81
Neurotrophins regulate dendritic growth in developing visual cortex. Neuron (1995) 3.64
LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite. Nature (1999) 3.55
Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron (1993) 3.44
Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci (1997) 3.41
Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res (1996) 3.18
Structural changes accompanying memory storage. Annu Rev Physiol (1993) 3.11
Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11
CREB: a major mediator of neuronal neurotrophin responses. Neuron (1997) 3.04
Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron (1997) 3.03
Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science (2002) 3.02
Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci (1996) 2.98
Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature (1994) 2.96
Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J Neurosci (2002) 2.94
Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Prog Neurobiol (2001) 2.88
Molecular mechanisms of memory acquisition, consolidation and retrieval. Curr Opin Neurobiol (2001) 2.78
Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron (1992) 2.69
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron (2002) 2.65
Rapid and selective induction of BDNF expression in the hippocampus during contextual learning. Nat Neurosci (2000) 2.64
Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc Natl Acad Sci U S A (1995) 2.58
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J Neurosci (2001) 2.51
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature (1995) 2.47
Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron (1994) 2.44
Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J (2001) 2.38
Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity. Proc Natl Acad Sci U S A (1998) 2.37
Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. J Neurosci (1999) 2.36
Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF. Science (1995) 2.30
Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice. J Neurosci (1999) 2.26
Learning deficit in BDNF mutant mice. Eur J Neurosci (1997) 2.20
The neurotrophin hypothesis for synaptic plasticity. Trends Neurosci (2000) 2.18
Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J Neurosci (2000) 2.11
Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10
BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron (1991) 2.10
An increase in dendritic spine density on hippocampal CA1 pyramidal cells following spatial learning in adult rats suggests the formation of new synapses. Proc Natl Acad Sci U S A (1994) 2.06
Neurotrophin signal transduction by the Trk receptor. J Neurobiol (1994) 1.97
Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain. Exp Neurol (2000) 1.91
Localized sources of neurotrophins initiate axon collateral sprouting. J Neurosci (1998) 1.90
Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons. Science (2001) 1.89
Destabilization of cortical dendrites and spines by BDNF. Neuron (1999) 1.88
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell (1993) 1.84
Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron (1998) 1.84
Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience (1997) 1.84
Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo. J Neurosci (2002) 1.80
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79
D.O. Hebb: The Organization of Behavior, Wiley: New York; 1949. Brain Res Bull (2000) 1.74
Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis. Neuron (1991) 1.74
BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus (2002) 1.71
The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70
Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J (1994) 1.68
Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain Res (1998) 1.67
Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behav Neurosci (1998) 1.57
Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57
Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats. Brain Res (1999) 1.56
BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain Res Mol Brain Res (1998) 1.53
BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons. J Cell Sci (1998) 1.52
A role for BDNF in the late-phase of hippocampal long-term potentiation. Neuropharmacology (1999) 1.49
Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1. Proc Natl Acad Sci U S A (1997) 1.47
Neurotrophins and activity-dependent plasticity. Prog Brain Res (2000) 1.47
Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience (2000) 1.47
Pattern of dendritic branching in occipital cortex of rats reared in complex environments. Exp Neurol (1973) 1.46
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience (1999) 1.44
Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment? Exp Physiol (2000) 1.44
TrkB signaling modulates spine density and morphology independent of dendrite structure in cultured neonatal Purkinje cells. J Neurosci (1998) 1.43
Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Brain Res Mol Brain Res (1998) 1.42
A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell (1995) 1.37
Acute intrahippocampal infusion of BDNF induces lasting potentiation of synaptic transmission in the rat dentate gyrus. J Neurophysiol (1998) 1.36
TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections. J Neurosci (1998) 1.36
BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels. Eur J Neurosci (1995) 1.31
Mechanisms for memory types differ. Nature (1998) 1.31
Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience (1998) 1.27
Trophic regulation of synaptic plasticity. J Neurobiol (1999) 1.27
Ultrastructural localization of full-length trkB immunoreactivity in rat hippocampus suggests multiple roles in modulating activity-dependent synaptic plasticity. J Neurosci (1999) 1.26
Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment. Neurosci Lett (1992) 1.25
Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1. Nature (1996) 1.25
GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (1995) 1.25
Spatial training in a complex environment and isolation alter the spine distribution differently in rat CA1 pyramidal cells. J Comp Neurol (1997) 1.23
Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation. Proc Natl Acad Sci U S A (1993) 1.23
5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. J Neurosci (1997) 1.19
Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci (2006) 5.89
Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J Neurosci (2002) 2.94
Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo. J Neurosci (2007) 2.57
Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo. Eur J Neurosci (2010) 2.15
Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo. J Neurosci (2002) 1.80
Novel translational control in Arc-dependent long term potentiation consolidation in vivo. J Biol Chem (2009) 1.52
Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. Mol Cell (2010) 1.38
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia. Biol Psychiatry (2011) 1.36
Identification of genes co-upregulated with Arc during BDNF-induced long-term potentiation in adult rat dentate gyrus in vivo. Eur J Neurosci (2006) 1.35
BDNF mechanisms in late LTP formation: A synthesis and breakdown. Neuropharmacology (2013) 1.22
BDNF-induced LTP in dentate gyrus is impaired with age: analysis of changes in cell signaling events. Neurobiol Aging (2004) 1.18
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. J Neurochem (2006) 1.18
Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy. Curr Opin Drug Discov Devel (2006) 1.17
The role of neurotrophins in neurotransmitter release. Neuroscientist (2002) 1.17
Activity-dependent local translation of matrix metalloproteinase-9. J Neurosci (2012) 1.10
Bursts of high-frequency stimulation trigger rapid delivery of pre-existing alpha-CaMKII mRNA to synapses: a mechanism in dendritic protein synthesis during long-term potentiation in adult awake rats. Eur J Neurosci (2003) 1.08
MicroRNA regulation of the synaptic plasticity-related gene Arc. PLoS One (2012) 1.07
How, when, and where new inhibitory neurons release neurotransmitters in the adult olfactory bulb. J Neurosci (2010) 1.06
Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNF-induced long-term potentiation. Neural Plast (2007) 1.05
Correlated calcium uptake and release by mitochondria and endoplasmic reticulum of CA3 hippocampal dendrites after afferent synaptic stimulation. J Neurosci (2002) 1.02
The coupling of a trkB tyrosine residue to LTP. Trends Neurosci (2003) 1.00
Balancing Arc synthesis, mRNA decay, and proteasomal degradation: maximal protein expression triggered by rapid eye movement sleep-like bursts of muscarinic cholinergic receptor stimulation. J Biol Chem (2012) 0.99
Learning modulation by endogenous hippocampal IL-1: blockade of endogenous IL-1 facilitates memory formation. Hippocampus (2004) 0.99
Consolidation and translation regulation. Learn Mem (2012) 0.99
Object-place recognition learning triggers rapid induction of plasticity-related immediate early genes and synaptic proteins in the rat dentate gyrus. Neural Plast (2009) 0.93
Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities. PLoS One (2009) 0.92
Social Defeat during Adolescence and Adulthood Differentially Induce BDNF-Regulated Immediate Early Genes. Front Behav Neurosci (2011) 0.92
Chronic fluoxetine induces region-specific changes in translation factor eIF4E and eEF2 activity in the rat brain. Eur J Neurosci (2006) 0.90
Selective survival and maturation of adult-born dentate granule cells expressing the immediate early gene Arc/Arg3.1. PLoS One (2009) 0.89
Modulation of neuronal calcium signaling by neurotrophic factors. Int J Dev Neurosci (2002) 0.88
Additive viability-loss following hsp70/hsc70 double interference and Hsp90 inhibition in two breast cancer cell lines. Oncol Rep (2007) 0.88
Early activation of extracellular signal-regulated kinase signaling pathway in the hippocampus is required for short-term memory formation of a fear-motivated learning. Cell Mol Neurobiol (2006) 0.84
Impairment of in vivo theta-burst long-term potentiation and network excitability in the dentate gyrus of synaptopodin-deficient mice lacking the spine apparatus and the cisternal organelle. Hippocampus (2009) 0.84
Selective viral transduction of adult-born olfactory neurons for chronic in vivo optogenetic stimulation. J Vis Exp (2011) 0.82
Post-transcriptional effects and interactions between chronic mild stress and acute sleep deprivation: regulation of translation factor and cytoplasmic polyadenylation element-binding protein phosphorylation. Behav Brain Res (2012) 0.80
Enhanced cognitive function and antidepressant-like effects after krill oil supplementation in rats. Lipids Health Dis (2013) 0.80
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis. Acta Neuropathol (2014) 0.80
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLoS One (2012) 0.79
Synaptically driven Ca2+ release in hippocampal neurons. J Neurophysiol (2003) 0.75
[Oxygen therapy during Argentine-based national and international flights]. Medicina (B Aires) (2008) 0.75