PubRank

Lari Lehtiö

Author PubWeight™ 25.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch. J Biol Chem 2009 1.39
2 Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78. PLoS One 2010 1.33
3 PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA. J Biol Chem 2010 1.32
4 Structural basis of selective inhibition of human tankyrases. J Med Chem 2012 1.25
5 Comparative structural analysis of human DEAD-box RNA helicases. PLoS One 2010 1.21
6 Comparative structural analysis of lipid binding START domains. PLoS One 2011 1.19
7 Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim. FEBS Lett 2008 1.13
8 Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion. FEBS J 2007 1.09
9 A trimetal site and substrate distortion in a family II inorganic pyrophosphatase. J Biol Chem 2006 1.03
10 Structural studies of metal ions in family II pyrophosphatases: the requirement for a Janus ion. Biochemistry 2004 0.93
11 Crystal structure of the N-terminal NC4 domain of collagen IX, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (LNS) domain family. J Biol Chem 2007 0.91
12 Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors. Eur J Pharm Sci 2013 0.89
13 Structural studies of tri-functional human GART. Nucleic Acids Res 2010 0.88
14 Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4. PLoS One 2013 0.88
15 Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J Med Chem 2013 0.88
16 Screening and structural analysis of flavones inhibiting tankyrases. J Med Chem 2013 0.85
17 para-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitors. ChemMedChem 2013 0.84
18 Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite. PLoS One 2012 0.84
19 Homogeneous screening assay for human tankyrase. J Biomol Screen 2012 0.83
20 Structure of the Streptococcus agalactiae family II inorganic pyrophosphatase at 2.80 A resolution. Acta Crystallogr D Biol Crystallogr 2007 0.82
21 Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif. J Biol Chem 2010 0.81
22 Crystallization and preliminary crystallographic analysis of two Streptococcus agalactiae proteins: the family II inorganic pyrophosphatase and the serine/threonine phosphatase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.80
23 The crystal structure of the Dachshund domain of human SnoN reveals flexibility in the putative protein interaction surface. PLoS One 2010 0.80
24 Substrate specificity and oligomerization of human GMP synthetase. J Mol Biol 2013 0.79
25 The structure of Pseudomonas P51 Cl-muconate lactonizing enzyme: co-evolution of structure and dynamics with the dehalogenation function. Protein Sci 2003 0.77
26 Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2. FEBS J 2006 0.77