Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy.

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Published in Br J Cancer on October 19, 2010

Authors

A M Hong1, T A Dobbins, C S Lee, D Jones, G B Harnett, B K Armstrong, J R Clark, C G Milross, J Kim, C J O'Brien, B R Rose

Author Affiliations

1: Department of Radiation Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Building 27, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia. ahon6809@mail.usyd.edu.au

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Malignant tumours of the heart: a review of tumour type, diagnosis and therapy. Clin Oncol (R Coll Radiol) (2007) 2.67

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Neonatal detection of developmental dysplasia of the hip (DDH) J Bone Joint Surg Br (1998) 2.56

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Scientific publication productivity of Korean medical colleges: an analysis of 1988-1999 MEDLINE papers. J Korean Med Sci (2000) 2.44

Cyclization of eucaryotic deoxyribonucleic acid fragments. J Mol Biol (1970) 2.43

Cutaneous malignant melanoma and indicators of total accumulated exposure to the sun: an analysis separating histogenetic types. J Natl Cancer Inst (1984) 2.39

Relationship of cutaneous malignant melanoma to individual sunlight-exposure habits. J Natl Cancer Inst (1986) 2.39

Emergence of gentamicin- and methicillin-resistant Staphylococcus aureus strains in New York City hospitals. J Clin Microbiol (1981) 2.39

Distinct functional phenotypes of cloned Ia-restricted helper T cells. J Exp Med (1985) 2.39

Design of biomimetic fibrillar interfaces: 1. Making contact. J R Soc Interface (2004) 2.38

Elective lymph node dissection in patients with primary melanoma of the trunk and limbs treated at the Sydney Melanoma unit from 1960 to 1991. J Am Coll Surg (1995) 2.38

Giant aneurysm of main pulmonary artery. Ann Thorac Surg (1996) 2.36

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The TAPS project. 6: New long-stay psychiatric patients and social deprivation. Br J Psychiatry (1992) 2.29

Electron microscope studies of heteroduplex DNA from a deletion mutant of bacteriophage phiX-174. Proc Natl Acad Sci U S A (1972) 2.29

Quality of life measures in health care. II: Design, analysis, and interpretation. BMJ (1992) 2.28

Mutations affecting expression of the rosy locus in Drosophila melanogaster. Genetics (1987) 2.27

Retrorectal cystic hamartoma: report of 5 cases with malignancy arising in 2. Arch Pathol Lab Med (2000) 2.27

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Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proc Natl Acad Sci U S A (1997) 2.11

Genetic transfer and bacterial taxonomy. Bacteriol Rev (1970) 2.10

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L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. Eur J Neurosci (1998) 2.10

Expression of chemokine receptors by subsets of neurons in the central nervous system. J Immunol (1997) 2.10

Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10

Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J Immunol (1990) 2.09

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Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months. J Am Coll Cardiol (1999) 2.09

Use of rifabutin with protease inhibitors for human immunodeficiency virus-infected patients with tuberculosis. Clin Infect Dis (2000) 2.08

Concentration of ofloxacin in canine prostate tissue and prostate fluid after intraprostatic injection of biodegradable sustained-releasing microspheres containing ofloxacin. J Urol (2000) 2.07

High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice. Nat Biotechnol (1996) 2.07

Effects of exercise during long-term support with a left ventricular assist device. Results of the experience with left ventricular assist device with exercise (EVADE) pilot trial. Circulation (1997) 2.06

A review of the effects of random measurement error on relative risk estimates in epidemiological studies. Int J Epidemiol (1989) 2.05

Orthostatic hypotension as a risk factor for stroke: the atherosclerosis risk in communities (ARIC) study, 1987-1996. Stroke (2000) 2.05

Predictions of future cases of asbestos-related disease among former miners and millers of crocidolite in Western Australia. Med J Aust (1990) 2.05

Melasma: histopathological characteristics in 56 Korean patients. Br J Dermatol (2002) 2.05