Published in Development on November 01, 2010
Claudins and the modulation of tight junction permeability. Physiol Rev (2013) 2.05
Neural tube defects. Annu Rev Neurosci (2014) 1.69
Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis. J Cell Sci (2013) 1.63
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. Cancer Res (2012) 1.50
A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells. PLoS Comput Biol (2016) 1.42
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts. Elife (2017) 1.38
Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Mol Biol Cell (2012) 1.15
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem (2012) 1.10
Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression. PLoS One (2012) 1.07
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer. J Biol Chem (2013) 1.07
Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer. Nucleic Acids Res (2013) 1.03
Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. Proc Natl Acad Sci U S A (2013) 1.01
Mechanisms of tissue fusion during development. Development (2012) 0.99
Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1. Cancer Biol Ther (2014) 0.96
Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism. Cell Death Dis (2012) 0.94
How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals. Cell Mol Life Sci (2012) 0.92
Roles for claudins in alveolar epithelial barrier function. Ann N Y Acad Sci (2012) 0.92
Claudins and alveolar epithelial barrier function in the lung. Ann N Y Acad Sci (2012) 0.92
Genome-scale study of transcription factor expression in the branching mouse lung. Dev Dyn (2012) 0.91
Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning. Dev Biol (2011) 0.91
Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome. Am J Hum Genet (2014) 0.90
A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion. J Am Soc Nephrol (2015) 0.90
Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer. Exp Biol Med (Maywood) (2015) 0.88
Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell (2015) 0.88
GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. Sci Rep (2016) 0.88
Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. EBioMedicine (2015) 0.86
Epithelial fusion during neural tube morphogenesis. Birth Defects Res A Clin Mol Teratol (2012) 0.86
Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse. Hum Mol Genet (2011) 0.86
Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer. J Cancer (2015) 0.84
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J Cell Biol (2015) 0.84
Association between genetic variations in GRHL2 and noise-induced hearing loss in Chinese high intensity noise exposed workers: a case-control analysis. Ind Health (2013) 0.84
Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction. Elife (2015) 0.83
Confirmation of GRHL2 as the gene for the DFNA28 locus. Am J Med Genet A (2013) 0.83
Role of grainyhead-like 2 in the formation of functional tight junctions. Tissue Barriers (2013) 0.80
The functions of grainy head-like proteins in animals and fungi and the evolution of apical extracellular barriers. PLoS One (2012) 0.80
Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherin. Acta Biochim Biophys Sin (Shanghai) (2016) 0.80
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer. Oncogenesis (2017) 0.80
Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure. Development (2016) 0.78
Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer. Int J Clin Exp Pathol (2014) 0.78
Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2. Mol Cell Biol (2016) 0.78
Progress and prospects in human genetic research into age-related hearing impairment. Biomed Res Int (2014) 0.77
WAVE2 regulates epithelial morphology and cadherin isoform switching through regulation of Twist and Abl. PLoS One (2013) 0.77
Neural tube closure: cellular, molecular and biomechanical mechanisms. Development (2017) 0.76
Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition. Mol Biol Cell (2016) 0.76
Midline craniofacial malformations with a lipomatous cephalocele are associated with insufficient closure of the neural tube in the tuft mouse. Birth Defects Res A Clin Mol Teratol (2014) 0.76
Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial-Mesenchymal Transition: Effects on Anoikis. Mol Cancer Res (2016) 0.76
Characterization of Chicken MMP13 Expression and Genetic Effect on Egg Production Traits of Its Promoter Polymorphisms. G3 (Bethesda) (2016) 0.75
Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary. Dev Dyn (2016) 0.75
A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT). Cell Death Dis (2016) 0.75
Grhl2 is required in nonneural tissues for neural progenitor survival and forebrain development. Genesis (2015) 0.75
A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Dis Model Mech (2016) 0.75
Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium. Cell Death Differ (2017) 0.75
Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells. Cell Cycle (2017) 0.75
A tail of two voltages: Proteomic comparison of the three electric organs of the electric eel. Sci Adv (2017) 0.75
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer. Am J Transl Res (2017) 0.75
Claudins are essential for cell shape changes and convergent extension movements during neural tube closure. Dev Biol (2017) 0.75
Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet (2005) 13.77
Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol (2003) 9.08
Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med (2008) 5.89
Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest (2005) 5.51
Lrp5 functions in bone to regulate bone mass. Nat Med (2011) 5.33
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A (2003) 5.08
Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol (2007) 4.99
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med (2005) 4.84
Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science (2003) 4.58
Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol (2008) 4.56
The renal arterial resistance index and renal allograft survival. N Engl J Med (2003) 4.36
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med (2009) 4.07
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat Immunol (2006) 3.98
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet (2009) 3.73
An iron delivery pathway mediated by a lipocalin. Mol Cell (2002) 3.38
Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care (2007) 3.29
Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Biol (2005) 3.28
The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med (2011) 3.20
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci (2013) 3.11
Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med (2008) 3.10
Platelet-derived serotonin mediates liver regeneration. Science (2006) 2.98
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study. J Am Coll Cardiol (2012) 2.97
Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol (2004) 2.96
Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes. Kidney Int (2011) 2.94
Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity. Am J Nephrol (2004) 2.91
Activation of the peripheral endocannabinoid system in human obesity. Diabetes (2005) 2.90
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel. Circ Res (2006) 2.67
Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell (2009) 2.60
Weight loss and the renin-angiotensin-aldosterone system. Hypertension (2005) 2.58
Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50
Kidney NGAL is a novel early marker of acute injury following transplantation. Pediatr Nephrol (2006) 2.48
Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum Mol Genet (2004) 2.45
Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension (2004) 2.41
Serotonin regulates mammary gland development via an autocrine-paracrine loop. Dev Cell (2004) 2.40
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. PLoS Biol (2009) 2.40
Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance. Cell Metab (2013) 2.38
Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension (2010) 2.38
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J (2007) 2.34
Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens (2006) 2.34
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A (2002) 2.32
Periadventitial fat releases a vascular relaxing factor. FASEB J (2002) 2.29
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell (2003) 2.28
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage. Circ Res (2007) 2.25
A unique central tryptophan hydroxylase isoform. Biochem Pharmacol (2003) 2.23
Lipocalin 2 is essential for chronic kidney disease progression in mice and humans. J Clin Invest (2010) 2.23
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning. Nat Med (2002) 2.20
Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease. Pediatr Nephrol (2006) 2.18
Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia. Hypertension (2007) 2.17
Retinol-binding protein 4 in human obesity. Diabetes (2006) 2.17
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation (2003) 2.15
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells. Nat Genet (2006) 2.10
A stomatin-domain protein essential for touch sensation in the mouse. Nature (2006) 2.08
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex. Nat Chem Biol (2010) 2.06
Acquired Brugada syndrome. Am J Cardiol (2003) 2.05
Association between adiponectin and mediators of inflammation in obese women. Diabetes (2003) 2.05
Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol (2011) 2.04
Using Google Earth to conduct a neighborhood audit: reliability of a virtual audit instrument. Health Place (2010) 2.03
Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies. Am J Kidney Dis (2002) 2.01
Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci U S A (2009) 2.01
Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension (2010) 2.01
Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol (2007) 1.99
The sympathetic nervous system in hypertension: assessment by blood pressure variability and ganglionic blockade. J Hypertens (2003) 1.98
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element. Mol Cell Biol (2005) 1.96
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. J Cell Biol (2004) 1.92
Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils. J Am Soc Nephrol (2002) 1.92
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest (2013) 1.92
C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis. J Am Soc Nephrol (2008) 1.92
Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss. Obes Res (2004) 1.91
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element. Genes Dev (2008) 1.90
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema. Stroke (2008) 1.90
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization. Cardiovasc Res (2003) 1.89
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension (2005) 1.89
Dysfunction of dysferlin-deficient hearts. J Mol Med (Berl) (2007) 1.89
Lin28 sustains early renal progenitors and induces Wilms tumor. Genes Dev (2014) 1.87
Resistin gene expression in human adipocytes is not related to insulin resistance. Obes Res (2002) 1.86
WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny. Kidney Int (2008) 1.86
Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons. Kidney Int (2008) 1.85
Autonomic nervous system and blood pressure regulation in RGS2-deficient mice. Am J Physiol Regul Integr Comp Physiol (2005) 1.84
Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem (2010) 1.83
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis (2010) 1.83
Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea. J Am Soc Nephrol (2003) 1.83
Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol (2010) 1.82
Biomarkers in acute and chronic kidney disease. Curr Opin Nephrol Hypertens (2008) 1.81
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension (2008) 1.81
Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension. J Hypertens (2002) 1.79
RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells. Proc Natl Acad Sci U S A (2007) 1.78
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. PLoS Genet (2009) 1.77
Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation (2009) 1.77
Axonal transcription factors signal retrogradely in lesioned peripheral nerve. EMBO J (2012) 1.77