What are biomarkers?

PubWeight™: 1.80‹?› | Rank: Top 3%

🔗 View Article (PMC 3078627)

Published in Curr Opin HIV AIDS on November 01, 2010

Authors

Kyle Strimbu1, Jorge A Tavel

Author Affiliations

1: Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Articles citing this

Overview of the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project. Adv Nutr (2016) 1.22

DNA methylation biomarkers: cancer and beyond. Genes (Basel) (2014) 1.11

Biomarkers in acute lung injury--marking forward progress. Crit Care Clin (2011) 0.95

Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer? Oncotarget (2015) 0.95

Eye Tracking Reveals Abnormal Visual Preference for Geometric Images as an Early Biomarker of an Autism Spectrum Disorder Subtype Associated With Increased Symptom Severity. Biol Psychiatry (2015) 0.93

A proposed panel of biomarkers of healthy ageing. BMC Med (2015) 0.90

Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing. BMC Med Genomics (2015) 0.89

Circulating Tumor Cells: Who is the Killer? Cancer Microenviron (2014) 0.87

Inhibition-Based Biomarkers for Autism Spectrum Disorder. Neurotherapeutics (2015) 0.86

Identifying biomarkers as diagnostic tools in kidney transplantation. Expert Rev Mol Diagn (2011) 0.83

Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives. Mem Inst Oswaldo Cruz (2015) 0.82

Can Molecular Biomarkers Change the Paradigm of Pancreatic Cancer Prognosis? Biomed Res Int (2016) 0.82

Minireview: Clinical severity in sickle cell disease: the challenges of definition and prognostication. Exp Biol Med (Maywood) (2016) 0.82

Electrochemistry-based approaches to low cost, high sensitivity, automated, multiplexed protein immunoassays for cancer diagnostics. Analyst (2015) 0.81

An Alzheimer's Disease-Derived Biomarker Signature Identifies Parkinson's Disease Patients with Dementia. PLoS One (2016) 0.81

Circulating glioma biomarkers. Neuro Oncol (2014) 0.80

Multimodal Imaging Signatures of Parkinson's Disease. Front Neurosci (2016) 0.79

Omics-Based Biomarkers: Application of Metabolomics in Neuropsychiatric Disorders. Int J Neuropsychopharmacol (2015) 0.79

Allergic asthma biomarkers using systems approaches. Front Genet (2014) 0.79

Temporal bone carcinoma: a first glance beyond the conventional clinical and pathological prognostic factors. Eur Arch Otorhinolaryngol (2015) 0.78

Metabolomics to Explore Impact of Dairy Intake. Nutrients (2015) 0.78

Contemporary approaches for imaging skeletal metastasis. Bone Res (2015) 0.78

The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism. Metabolomics (2017) 0.77

The Importance of Endophenotypes to Evaluate the Relationship between Genotype and External Phenotype. Int J Mol Sci (2017) 0.77

The potential use of biomarkers in predicting contrast-induced acute kidney injury. Int J Nephrol Renovasc Dis (2016) 0.77

Genomic Biomarkers for Breast Cancer Risk. Adv Exp Med Biol (2016) 0.77

Sources and Functions of Extracellular Small RNAs in Human Circulation. Annu Rev Nutr (2016) 0.77

Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics. Biomed Res Int (2015) 0.77

Potential Biomarkers of Fat Loss as a Feature of Cancer Cachexia. Mediators Inflamm (2015) 0.77

Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers. Int J Mol Sci (2016) 0.76

The American Geriatrics Society/National Institute on Aging Bedside-to-Bench Conference: Research Agenda on Delirium in Older Adults. J Am Geriatr Soc (2015) 0.76

A Review of Cutoffs for Nutritional Biomarkers. Adv Nutr (2016) 0.76

Can innate and autoimmune reactivity forecast early and advance stages of age-related macular degeneration? Autoimmun Rev (2017) 0.76

The importance of early life in childhood obesity and related diseases: a report from the 2014 Gravida Strategic Summit. J Dev Orig Health Dis (2014) 0.76

Correlation of biomarkers thiobarbituric acid reactive substance, nitric oxide and central subfield and cube average thickness in diabetic retinopathy: a cross-sectional study. Int J Retina Vitreous (2016) 0.76

Skeletal Muscle Quantitative Nuclear Magnetic Resonance Imaging and Spectroscopy as an Outcome Measure for Clinical Trials. J Neuromuscul Dis (2016) 0.76

Translational Prospects and Challenges in Human Induced Pluripotent Stem Cell Research in Drug Discovery. Cells (2016) 0.76

Moyamoya Biomarkers. J Korean Neurosurg Soc (2015) 0.76

Biomarkers of Reflux Disease. Clin Gastroenterol Hepatol (2015) 0.75

Overall Adiposity, Adipose Tissue Distribution, and Endometriosis: A Systematic Review. Nurs Res (2016) 0.75

Elevated blood plasma levels of epinephrine, norepinephrine, tyrosine hydroxylase, TGFβ1, and TNFα associated with high-altitude pulmonary edema in an Indian population. Ther Clin Risk Manag (2016) 0.75

The Role of Clinical Records in Narrative Medicine: A Discourse of Message. Perm J (2016) 0.75

Changes in Membrane Receptors and Ion Channels as Potential Biomarkers for Osteoarthritis. Front Physiol (2015) 0.75

Serum Surfactant Protein D and Haptoglobin as Potential Biomarkers for Inflammatory Airway Disease in Horses. J Vet Intern Med (2015) 0.75

Big Data in Pharmaceutical R&D: Creating a Sustainable R&D Engine. Pharmaceut Med (2015) 0.75

Early prediction of typical outcome and mild developmental delay for prioritisation of service delivery for very preterm and very low birthweight infants: a study protocol. BMJ Open (2016) 0.75

Ultrashort time to echo magnetic resonance techniques for the musculoskeletal system. Quant Imaging Med Surg (2016) 0.75

A Timely Shift from Shotgun to Targeted Proteomics and How It Can Be Groundbreaking for Cancer Research. Front Oncol (2017) 0.75

Identification of new biosignatures for clinical outcomes in stable coronary artery disease - The study protocol and initial observations of a prospective follow-up study in Taiwan. BMC Cardiovasc Disord (2017) 0.75

Asymmetric Dimethylarginine and Its Relation As a Biomarker in Nephrologic Diseases. Biomark Insights (2016) 0.75

Reliability of Potential Pain Biomarkers in the Saliva of Healthy Subjects: Inter-Individual Differences and Intersession Variability. PLoS One (2016) 0.75

C-reactive protein levels in the perioperative period as a predictive marker of endoscopic recurrence after ileo-colonic resection for Crohn's disease. Cell Death Discov (2016) 0.75

Circulating microRNAs as Potential Biomarkers of Infectious Disease. Front Immunol (2017) 0.75

Serum N-Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism. J Vet Intern Med (2016) 0.75

Random Forest Segregation of Drug Responses May Define Regions of Biological Significance. Front Comput Neurosci (2016) 0.75

A systematically structured review of biomarkers of dying in cancer patients in the last months of life; An exploration of the biology of dying. PLoS One (2017) 0.75

Biomarkers, Genetics, and Epigenetic Studies to Explore the Neurocognitive Effects of Anesthesia in Children. J Neurosurg Anesthesiol (2016) 0.75

The potential of spectral domain optical coherence tomography imaging based retinal biomarkers. Int J Retina Vitreous (2017) 0.75

Aptamer-Based Screens of Human Body Fluids for Biomarkers. Microarrays (Basel) (2015) 0.75

Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus. Dis Markers (2016) 0.75

Exploring Biomarkers for Alzheimer's Disease. J Clin Diagn Res (2016) 0.75

Materiomics for Oral Disease Diagnostics and Personal Health Monitoring: Designer Biomaterials for the Next Generation Biomarkers. OMICS (2016) 0.75

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis. Antimicrob Agents Chemother (2014) 0.75

Identification of Gingival Crevicular Fluid Sampling, Analytical Methods, and Oral Biomarkers for the Diagnosis and Monitoring of Periodontal Diseases: A Systematic Review. Dis Markers (2016) 0.75

Decrease in brain-derived neurotrophic factor at plasma level but not in serum concentrations in suicide behavior: A systematic review and meta-analysis. Brain Behav (2017) 0.75

Biomarkers in the assessment of oral mucositis in head and neck cancer patients: a systematic review and meta-analysis. Support Care Cancer (2017) 0.75

Machine learning and microsimulation techniques on the prognosis of dementia: A systematic literature review. PLoS One (2017) 0.75

A multiple biomarker assay for quality assessment of botanical drugs using a versatile microfluidic chip. Sci Rep (2017) 0.75

microRNAs Make the Call in Cancer Personalized Medicine. Front Cell Dev Biol (2017) 0.75

Personalized Computational Models as Biomarkers. J Pers Med (2017) 0.75

A Review of Biomarkers for Neurodegenerative Disease: Will They Swing Us Across the Valley? Neurol Ther (2017) 0.75

Progress and roadblocks in the search for brain-based biomarkers of autism and attention-deficit/hyperactivity disorder. Transl Psychiatry (2017) 0.75

Renal cell carcinoma: the search for a reliable biomarker. Transl Cancer Res (2017) 0.75

Gene-wide Association Study Reveals RNF122 Ubiquitin Ligase as a Novel Susceptibility Gene for Attention Deficit Hyperactivity Disorder. Sci Rep (2017) 0.75

Transcriptome predictors of coral survival and growth in a highly variable environment. Ecol Evol (2017) 0.75

Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets. Nat Rev Gastroenterol Hepatol (2017) 0.75

Articles by these authors

Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans. Blood (2007) 1.52

Regulatory approvals in a large multinational clinical trial: the ESPRIT experience. Control Clin Trials (2002) 1.37

Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease. PLoS One (2012) 1.31

Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals. Hum Gene Ther (2005) 1.17

The quality of informed consent in a clinical research study in Thailand. IRB (2005) 1.13

CD4 cell response to 3 doses of subcutaneous interleukin 2: meta-analysis of 3 Vanguard studies. Clin Infect Dis (2004) 1.10

Induction and maintenance therapy with intermittent interleukin-2 in HIV-1 infection. Blood (2004) 1.06

CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients. J Infect Dis (2008) 0.99

A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study. PLoS Clin Trials (2006) 0.95

Post-trial access to tested interventions: the views of IRB/REC chair, investigators, and research participants in a multinational HIV/AIDS study. AIDS Res Hum Retroviruses (2006) 0.94

Analysis of generic nevirapine products in developing countries. JAMA (2003) 0.88

Informed consent: practices and views of investigators in a multinational clinical trial. IRB (2006) 0.83

Antiretroviral drug content in products from developing countries. Clin Infect Dis (2004) 0.82

Protocol Development Program: A Novel Approach to Overcoming Barriers to Clinical Research. Monitor (Assoc Clin Pharmacol) (2013) 0.77

Therapeutic use of interleukin-2 in HIV-infected patients. Curr Opin Pharmacol (2002) 0.75