Published in Br J Cancer Suppl on June 01, 1978
Pharmacokinetic considerations in testing hypoxic cell radiosensitizers in mouse tumours. Br J Cancer (1979) 1.42
Phenytoin shortens the half-life of the hypoxic cell radiosensitizer misonidazole in man: implications for possible reduced toxicity. Br J Cancer (1980) 1.33
Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice. Br J Cancer (1979) 1.23
In vivo assessment of basic 2-nitroimidazole radiosensitizers. Br J Cancer (1982) 1.00
The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Transl Oncol (2010) 0.98
Changes in nerve conduction velocity in the mouse after acute and chronic administration of nitroimidazoles. Br J Cancer (1979) 0.95
Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiat Res (2008) 0.94
Peripheral electrophysiological parameters in mice treated with misonidazole. Br J Cancer (1979) 0.85
Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial. Br J Cancer (1982) 0.85
Misonidazole and MTDQ in combination: cytotoxic and radiosensitizing properties in hypoxic mammalian cells. Br J Cancer (1979) 0.83
Phenytoin-induced changes in the pharmacokinetics of misonidazole in radiotherapy patients. Br J Cancer (1981) 0.81
Hypoxic cell sensitization to radiation damage by a new radiosensitizer: cis-dichloro-bis(1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole-N3)platinum(II) (flap). Br J Cancer (1982) 0.79
The role of dexamethasone in the modification of misonidazole pharmacokinetics. Br J Cancer (1983) 0.75
Effect of acute and chronic misonidazole administration on peripheral-nerve electrophysiology in mice. Br J Cancer (1980) 0.75
Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses. Br J Cancer (1977) 5.58
Clinical testing of the radiosensitiser Ro-07-0582. I. Dose tolerance, serum and tumour concentrations. Clin Radiol (1976) 3.55
Clinical phase I study of the hypoxic cell radiosensitizer RO-07-0582, a 2-nitroimidazole derivative. Radiology (1977) 2.55
Letter: "High-dose" metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials. Br J Radiol (1974) 1.87
Peripheral neuropathy caused by chemical agents. CRC Crit Rev Toxicol (1973) 1.44
Letter: Metronidazole and tissue zinc/iron ratio in cancer therapy. Lancet (1976) 0.97
A more powerful robust sib-pair test of linkage for quantitative traits. Genet Epidemiol (1989) 4.17
A wakeful hypometabolic physiologic state. Am J Physiol (1971) 2.82
Evidence for mendelian inheritance in the pathogenesis of lung cancer. J Natl Cancer Inst (1990) 2.72
Radiation and high-dose metronidazole in supratentorial glioblastomas. N Engl J Med (1976) 2.56
Clinical phase I study of the hypoxic cell radiosensitizer RO-07-0582, a 2-nitroimidazole derivative. Radiology (1977) 2.55
Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med (1996) 2.49
Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet (1993) 2.12
Risk adjustment and Medicare: taking a closer look. Health Aff (Millwood) (1997) 2.08
Epidemiologic study of cystic fibrosis: design and implementation of a prospective, multicenter, observational study of patients with cystic fibrosis in the U.S. and Canada. Pediatr Pulmonol (1999) 2.05
Presence of nucleoside triphosphate phosphohydrolase activity in purified virions of reovirus. J Virol (1970) 2.04
New intermediate subviral particles in the in vitro uncoating of reovirus virions by chymotrypsin. J Virol (1973) 1.99
Phase 1 study of high-dose metronidazole: a specific in vivo and in vitro radiosensitizer of hypoxic cells. Radiology (1975) 1.90
Letter: "High-dose" metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials. Br J Radiol (1974) 1.87
A marker for hypoxic cells in tumours with potential clinical applicability. Br J Cancer (1981) 1.85
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment. Antimicrob Agents Chemother (1981) 1.82
Fundamental dilemmas of the randomized clinical trial process: results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators. J Clin Oncol (1994) 1.79
Inhibition of Pseudomonas aeruginosa exoenzyme expression by subinhibitory antibiotic concentrations. Antimicrob Agents Chemother (1989) 1.69
Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cells. Cancer Res (1983) 1.67
Chemical radioprotection and radiosensitization of mammalian cells growing in vitro. Radiat Res (1973) 1.66
Measurement of PDT-induced hypoxia in Dunning prostate tumors by iodine-123-iodoazomycin arabinoside. J Nucl Med (1993) 1.64
Impact of microbiology practice on cumulative prevalence of respiratory tract bacteria in patients with cystic fibrosis. J Clin Microbiol (1999) 1.64
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical sites. J Clin Microbiol (1986) 1.60
A single-breath technique with variable flow rate to characterize nitric oxide exchange dynamics in the lungs. J Appl Physiol (1985) (2001) 1.54
Effectiveness of nitrofuran derivatives in sensitizing hypoxic mammalian cells to x rays. Br J Radiol (1973) 1.53
The relative importance of estrogen receptor analysis as a prognostic factor for recurrence or response to chemotherapy in women with breast cancer. Cancer (1980) 1.49
Pseudomonas aeruginosa lasR transcription correlates with the transcription of lasA, lasB, and toxA in chronic lung infections associated with cystic fibrosis. Infect Immun (1998) 1.45
Persistence of Pseudomonas aeruginosa during ciprofloxacin therapy of a cystic fibrosis patient: transient resistance to quinolones and protein F-deficiency. J Antimicrob Chemother (1990) 1.45
Relationship between amount of lung resected and outcome after lung volume reduction surgery. Ann Thorac Surg (2000) 1.44
Lung scan evaluation of thrombolytic therapy for pulmonary embolism. J Nucl Med (1995) 1.44
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Survival following bilateral staple lung volume reduction surgery for emphysema. Chest (1999) 1.39
A device for overcoming discoordination with metered-dose inhalers. J Allergy Clin Immunol (1993) 1.39
Detection of antibodies to Pseudomonas aeruginosa alginate extracellular polysaccharide in animals and cystic fibrosis patients by enzyme-linked immunosorbent assay. J Clin Microbiol (1983) 1.39
A study of linkage and association of body mass index in the Old Order Amish. Am J Med Genet C Semin Med Genet (2003) 1.38
Heritability of platelet function in families with premature coronary artery disease. J Thromb Haemost (2007) 1.37
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia. Int J Radiat Oncol Biol Phys (1986) 1.32
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
The neurotoxicity of misonidazole: pooling of data from five centres. Br J Radiol (1978) 1.31
Adrenocortical activity during meditation. Horm Behav (1978) 1.30
Hypoxic sensitizers--implications for radiation therapy. N Engl J Med (1979) 1.29
The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazole. Br J Radiol (1983) 1.29
Gold microspheres: a selective technique for producing biologically effective dose enhancement. Int J Radiat Biol (2000) 1.27
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Persistence mechanisms in Pseudomonas aeruginosa from cystic fibrosis patients undergoing ciprofloxacin therapy. Antimicrob Agents Chemother (1991) 1.24
Genome-wide meta-analyses of smoking behaviors in African Americans. Transl Psychiatry (2012) 1.23
Role of Alternaria and Penicillium spores in the pathogenesis of asthma. J Allergy Clin Immunol (1985) 1.22
Comparison of variance components, ANOVA and regression of offspring on midparent (ROMP) methods for SNP markers. Genet Epidemiol (2001) 1.21
A novel technique for measuring human tissue pO2 at the cellular level. Br J Cancer (1986) 1.21
Extraordinary effects of specific monovalent cations on activation of reovirus transcriptase by chymotrypsin in vitro. J Virol (1973) 1.20
Histopathology of human coronary atherosclerosis by quantifying its chemical composition with Raman spectroscopy. Circulation (1998) 1.20
High dose radiation therapy in the treatment of malignant gliomas: final report. Int J Radiat Oncol Biol Phys (1979) 1.20
Nitrofurans as radiosensitizers of hypoxic mammalian cells. Cancer Res (1972) 1.19
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
Inhibition of gamma-ray-induced degradation of E. coli Bs-1 DNA by infection with T1, T2 and T4 bacteriophage. Nature (1968) 1.19
Paraquat poisoning: manifestations and therapy. Am J Med (1975) 1.19
Increasing levels of hypoxia in prostate carcinoma correlate significantly with increasing clinical stage and patient age: an Eppendorf pO(2) study. Cancer (2000) 1.18
Bilateral carpal tunnel syndrome in childhood. A report of two sisters with mucolipidosis III (pseudo-Hurler polydystrophy). Neurology (1975) 1.18
Heritability of salt sensitivity in black Americans. Hypertension (1996) 1.17
Reovirus transcriptase activation in vitro: involvement of an endogenous uncoating activity in the second stage of the process. Intervirology (1974) 1.17
DNA strand breaks, repair, and survival in x-irradiated mammalian cells. Proc Natl Acad Sci U S A (1976) 1.16
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
Hypoxic regions exist in human prostate carcinoma. Urology (1999) 1.13
Comparison of sib-pair and variance-components methods for genomic screening. Genet Epidemiol (1997) 1.13
The detection and measurement of hypoxic cells in solid tumors. Cancer (1984) 1.12
Paraquat poisoning: new aspects of therapy. Q J Med (1976) 1.12
Segregation analysis of bronchial response to methacholine inhalation challenge in families with and without asthma. J Allergy Clin Immunol (1986) 1.11
Cicutoxin poisoning (water hemlock). Neurology (1975) 1.10
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia. J Nucl Med (1991) 1.10
Hypoxia in human prostate carcinoma: an Eppendorf PO2 study. Am J Clin Oncol (2001) 1.10
Single-arm, open-label phase II study of intravenously administered tirapazamine and radiation therapy for glioblastoma multiforme. J Clin Oncol (2000) 1.09
The significance of regional pulmonary function changes in bronchial asthma. Am J Med (1970) 1.09
Intracellular localization of radioactively labeled misonidazole in EMT-6-tumor cells in vitro. Int J Radiat Oncol Biol Phys (1982) 1.09
Radiobiological characterization of the inactivating events produced in mammalian cells by helium and heavy ions. Int J Radiat Oncol Biol Phys (1977) 1.08
Large airway constriction in allergic rhinitis. J Allergy Clin Immunol (1977) 1.08
Pulmonary clearance and hilar lymph node content in rats after particle exposure. Environ Res (1978) 1.08
Search for tb resonances in proton-proton collisions at √s=7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.07
Thoracoscopic carbon dioxide laser treatment of bullous emphysema. Lancet (1991) 1.07
Effects of breathing retraining in patients with chronic obstructive pulmonary disease. Chest (1981) 1.06
The transcendental meditation technique, adrenocortical activity, and implications for stress. Experientia (1978) 1.06
Optical properties of experimental prostate tumors in vivo. Photochem Photobiol (1993) 1.05
Search for a light Higgs boson decaying to long-lived weakly interacting particles in proton-proton collisions at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.05
Linkage and segregation analyses of apolipoproteins A1 and B, and lipoprotein cholesterol levels in a large pedigree with excess coronary heart disease: the Bogalusa Heart Study. Genet Epidemiol (1987) 1.04
Population transcript accumulation of Pseudomonas aeruginosa exotoxin A and elastase in sputa from patients with cystic fibrosis. Infect Immun (1992) 1.04
Letter: Studies on the radiosensitizing effect of oxygen in Chinese hamster cells. Int J Radiat Biol Relat Stud Phys Chem Med (1974) 1.04
Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis. Infect Immun (1997) 1.02
Chemical agents that promote chromatin compaction radiosensitize tumour cells. Int J Radiat Biol (2001) 1.01
Reovirus transcriptase activation in vitro: further studies on the facilitation phenomenon. Intervirology (1974) 1.01