Published in Brain Imaging Behav on March 01, 2009
The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder. Pharmacol Biochem Behav (2011) 1.29
A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression. Psychopharmacology (Berl) (2013) 0.99
Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive-compulsive symptoms. Psychopharmacology (Berl) (2013) 0.87
Glutamate system genes and brain volume alterations in pediatric obsessive-compulsive disorder: a preliminary study. Psychiatry Res (2012) 0.86
Association between the NMDA glutamate receptor GRIN2B gene and obsessive-compulsive disorder. J Psychiatry Neurosci (2012) 0.85
Imaging-genetics applications in child psychiatry. J Am Acad Child Adolesc Psychiatry (2010) 0.84
Glutamate and the Treatment of Obsessive-Compulsive Disorder. Psychopharm Rev (2010) 0.83
Whole-genome association analysis of treatment response in obsessive-compulsive disorder. Mol Psychiatry (2015) 0.81
An inherited small microdeletion at 15q13.3 in a patient with early-onset obsessive-compulsive disorder. PLoS One (2014) 0.79
The neurobiological link between OCD and ADHD. Atten Defic Hyperact Disord (2014) 0.79
Orbital frontal cortex in treatment-naïve pediatric obsessive-compulsive disorder. Psychiatry Res (2010) 0.79
NEUROBIOLOGICAL EVIDENCE SUPPORTING GLUTAMATE'S ROLE IN PEDIATRIC OBSESSIVE COMPULSIVE DISORDER. Child Adolesc Psychopharmacol News (2010) 0.75
The importance of the excitatory amino acid transporter 3 (EAAT3). Neurochem Int (2016) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry (2005) 58.92
Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry (1997) 41.93
Human MicroRNA targets. PLoS Biol (2004) 34.51
Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A (2002) 25.47
The assessment of anxiety states by rating. Br J Med Psychol (1959) 24.58
Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol (1967) 22.39
The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70
Children's Yale-Brown Obsessive Compulsive Scale: reliability and validity. J Am Acad Child Adolesc Psychiatry (1997) 7.10
The Yale Global Tic Severity Scale: initial testing of a clinician-rated scale of tic severity. J Am Acad Child Adolesc Psychiatry (1989) 6.98
A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res (1991) 6.26
Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat Rev Neurosci (2006) 5.70
Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biol Psychiatry (2007) 4.71
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature (2007) 4.59
A susceptibility gene for affective disorders and the response of the human amygdala. Arch Gen Psychiatry (2005) 4.33
Common Kibra alleles are associated with human memory performance. Science (2006) 3.30
Mechanisms of translational control by the 3' UTR in development and differentiation. Semin Cell Dev Biol (2005) 3.17
Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function. Hum Brain Mapp (2007) 2.36
Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol Psychiatry (2005) 2.29
A family study of obsessive-compulsive disorder. Am J Psychiatry (1995) 2.24
Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Arch Gen Psychiatry (2006) 2.23
A family study of obsessive-compulsive disorder. Arch Gen Psychiatry (2000) 2.03
Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Arch Gen Psychiatry (2006) 2.02
A.E. Bennett Research Award. Toward a neurodevelopmental model of of obsessive--compulsive disorder. Biol Psychiatry (1998) 1.88
Mapping structural brain alterations in obsessive-compulsive disorder. Arch Gen Psychiatry (2004) 1.70
Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder. Arch Gen Psychiatry (1999) 1.61
Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biol Psychiatry (2005) 1.52
Distinct structural and ionotropic roles of NMDA receptors in controlling spine and synapse stability. J Neurosci (2007) 1.50
Decrease in caudate glutamatergic concentrations in pediatric obsessive-compulsive disorder patients taking paroxetine. J Am Acad Child Adolesc Psychiatry (2000) 1.44
Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. NeuroRx (2006) 1.43
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls. J Am Acad Child Adolesc Psychiatry (2004) 1.41
Twin studies on obsessive-compulsive disorder: a review. Twin Res Hum Genet (2005) 1.41
Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: an optimized voxel-based morphometry study. Am J Psychiatry (2008) 1.40
Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study. Psychopharmacology (Berl) (2004) 1.39
Glutamatergic dysfunction in OCD. Neuropsychopharmacology (2005) 1.36
Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive-compulsive disorder. Am J Psychiatry (2004) 1.35
Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. Am J Med Genet (2002) 1.35
Regional gray matter abnormalities in obsessive-compulsive disorder: a voxel-based morphometry study. Biol Psychiatry (2005) 1.30
Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2007) 1.27
Frontostriatal measurement in treatment-naive children with obsessive-compulsive disorder. Arch Gen Psychiatry (1997) 1.26
Grey matter abnormalities in obsessive-compulsive disorder: statistical parametric mapping of segmented magnetic resonance images. Br J Psychiatry (2001) 1.23
DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biol Psychol (2007) 1.21
Decrease in thalamic volumes of pediatric patients with obsessive-compulsive disorder who are taking paroxetine. Arch Gen Psychiatry (2000) 1.16
Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder. Am J Hum Genet (2004) 1.13
A family study of early-onset obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2005) 1.13
A magnetic resonance spectroscopy investigation of obsessive-compulsive disorder and anxiety. Psychiatry Res (2006) 1.12
A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry. Mol Psychiatry (2002) 1.10
An open-label trial of riluzole, a glutamate antagonist, in children with treatment-resistant obsessive-compulsive disorder. J Child Adolesc Psychopharmacol (2007) 1.10
A family study of obsessive-compulsive disorder with pediatric probands. Am J Med Genet B Neuropsychiatr Genet (2005) 1.10
Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression. J Am Acad Child Adolesc Psychiatry (2004) 1.07
A manual and automated MRI study of anterior cingulate and orbito-frontal cortices, and caudate nucleus in obsessive-compulsive disorder: comparison with healthy controls and patients with schizophrenia. Psychiatry Res (2005) 1.06
The epidemiology and differential diagnosis of obsessive compulsive disorder. J Clin Psychiatry (1994) 1.03
Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study. Biol Psychiatry (2003) 1.03
Volumetric MRI study of key brain regions implicated in obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry (2006) 1.01
Volumetric investigation of the frontal-subcortical circuitry in patients with obsessive-compulsive disorder. J Neuropsychiatry Clin Neurosci (2004) 0.99
Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder. Psychopharmacology (Berl) (2003) 0.97
Increased medial thalamic creatine-phosphocreatine found by proton magnetic resonance spectroscopy in children with obsessive-compulsive disorder versus major depression and healthy controls. J Child Neurol (2006) 0.94
On the role of cortical glutamate in obsessive-compulsive disorder and attention-deficit hyperactivity disorder, two phenomenologically antithetical conditions. Acta Psychiatr Scand (2000) 0.94
Neurochemical analyses in pediatric obsessive-compulsive disorder in patients treated with cognitive-behavioral therapy. J Am Acad Child Adolesc Psychiatry (2003) 0.94
Imaging phenotypes and genotypes in schizophrenia. Neuroinformatics (2006) 0.91
Left anterior subregion of orbitofrontal cortex volume reduction and impaired organizational strategies in obsessive-compulsive disorder. J Psychiatr Res (2004) 0.91
Thalamic volume in pediatric obsessive-compulsive disorder patients before and after cognitive behavioral therapy. Biol Psychiatry (2000) 0.87
Brain anatomy and chemistry may predict treatment response in paediatric obsessive--compulsive disorder. Int J Neuropsychopharmacol (2001) 0.86
Genetic and imaging strategies in obsessive-compulsive disorder: potential implications for treatment development. Biol Psychiatry (2000) 0.83
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet (2006) 6.27
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci U S A (2009) 3.49
Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance? Schizophr Bull (2003) 2.76
Practice guideline for the treatment of patients with obsessive-compulsive disorder. Am J Psychiatry (2007) 2.53
Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Arch Gen Psychiatry (2006) 2.23
Evidence that 'food addiction' is a valid phenotype of obesity. Appetite (2011) 2.02
Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Arch Gen Psychiatry (2006) 2.02
The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet (2002) 1.98
Role of ethnicity in antipsychotic-induced weight gain and tardive dyskinesia: genes or environment? Pharmacogenomics (2013) 1.97
Age-related decline in white matter tract integrity and cognitive performance: a DTI tractography and structural equation modeling study. Neurobiol Aging (2010) 1.77
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia. Biol Psychiatry (2002) 1.66
Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eating. Obesity (Silver Spring) (2009) 1.65
Association between serotonin transporter gene and borderline personality disorder. J Psychiatr Res (2006) 1.64
Pharmacogenetics of psychotropic drug response. Am J Psychiatry (2004) 1.61
Suicide risk in bipolar patients: the role of co-morbid substance use disorders. Bipolar Disord (2003) 1.59
Comorbidity and pathophysiology of obsessive-compulsive disorder in schizophrenia: is there evidence for a schizo-obsessive subtype of schizophrenia? J Psychiatry Neurosci (2005) 1.49
Development of the corpus callosum in childhood, adolescence and early adulthood. Life Sci (2002) 1.47
Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response. Psychopharmacology (Berl) (2008) 1.46
Obsessive-compulsive spectrum disorders: a review of the evidence-based treatments. Can J Psychiatry (2009) 1.45
Medial temporal N-acetyl-aspartate in pediatric major depression. Psychiatry Res (2008) 1.44
Diffusion tensor tractography findings in schizophrenia across the adult lifespan. Brain (2010) 1.43
Connexin 50 gene on human chromosome 1q21 is associated with schizophrenia in matched case control and family-based studies. J Med Genet (2007) 1.42
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls. J Am Acad Child Adolesc Psychiatry (2004) 1.41
Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: an optimized voxel-based morphometry study. Am J Psychiatry (2008) 1.40
Pharmacogenetics in psychiatry satellite meeting at the American College of Neuropsychopharmacology, 2000. Neuropsychopharmacology (2002) 1.39
Psychological treatment of obsessive-compulsive disorder in patients with major depression: a pilot randomized controlled trial. Can J Psychiatry (2009) 1.39
Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study. Psychopharmacology (Berl) (2004) 1.39
Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive-compulsive disorder. Am J Psychiatry (2004) 1.35
Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism. Am J Med Genet (2002) 1.31
Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder. Prog Neuropsychopharmacol Biol Psychiatry (2007) 1.31
The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder. Pharmacol Biochem Behav (2011) 1.29
Early age at onset as a risk factor for poor outcome of bipolar disorder. J Psychiatr Res (2003) 1.27
Increased amygdala: hippocampal volume ratios associated with severity of anxiety in pediatric major depression. J Child Adolesc Psychopharmacol (2003) 1.26
Altered function and connectivity of the medial frontal cortex in pediatric obsessive-compulsive disorder. Biol Psychiatry (2010) 1.26
Amygdala and hippocampal volumes in familial early onset major depressive disorder. Biol Psychiatry (2007) 1.25
Development of CMX001 for the Treatment of Poxvirus Infections. Viruses (2010) 1.23
Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism. Neuropsychopharmacology (2002) 1.23
Reduced anterior cingulate glutamate in pediatric major depression: a magnetic resonance spectroscopy study. Biol Psychiatry (2005) 1.20
Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: preliminary findings. Neuropsychopharmacology (2004) 1.20
Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain. Arch Gen Psychiatry (2012) 1.20
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet (2009) 1.18
N-methyl-D-aspartate receptor NR2B subunit gene GRIN2B in schizophrenia and bipolar disorder: Polymorphisms and mRNA levels. Schizophr Res (2006) 1.18
Decision-making deficits and overeating: a risk model for obesity. Obes Res (2004) 1.16
Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity. Can J Psychiatry (2003) 1.15
Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia. Neuropsychobiology (2004) 1.10
Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. PLoS One (2012) 1.10
Developmental alterations of frontal-striatal-thalamic connectivity in obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry (2011) 1.09
Serotonin transporter polymorphisms and persistent, pervasive childhood aggression. Am J Psychiatry (2006) 1.08
The dopamine-4 receptor gene associated with binge eating and weight gain in women with seasonal affective disorder: an evolutionary perspective. Biol Psychiatry (2004) 1.07
Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression. J Am Acad Child Adolesc Psychiatry (2004) 1.07
Genetic aspects of pathological gambling: a complex disorder with shared genetic vulnerabilities. Addiction (2009) 1.06
Evidence for the gamma-amino-butyric acid type B receptor 1 (GABBR1) gene as a susceptibility factor in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2005) 1.06
The ZNF804A gene: characterization of a novel neural risk mechanism for the major psychoses. Neuropsychopharmacology (2011) 1.06
Brain imaging in pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry (2008) 1.06
Genetics of antipsychotic treatment emergent weight gain in schizophrenia. Pharmacogenomics (2006) 1.05
The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease. Arch Gen Psychiatry (2011) 1.05
Reduced superior temporal gyrus volume in young offspring of patients with schizophrenia. Am J Psychiatry (2004) 1.05
Gene for the serotonin transporter and ADHD: no association with two functional polymorphisms. Am J Med Genet B Neuropsychiatr Genet (2006) 1.04
Quantitative examination of a novel clustering method using magnetic resonance diffusion tensor tractography. Neuroimage (2008) 1.04
Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis. Pharmacogenomics (2010) 1.04
Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study. Biol Psychiatry (2003) 1.03
Investigation of the G protein subunit Galphaolf gene (GNAL) in attention deficit/hyperactivity disorder. J Psychiatr Res (2006) 1.03
Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder. Psychiatry Res (2009) 1.03
Personality and eating behaviors: a case-control study of binge eating disorder. Int J Eat Disord (2008) 1.03