Published in Digestion on November 01, 2010
From NAFLD to NASH to cirrhosis-new insights into disease mechanisms. Nat Rev Gastroenterol Hepatol (2013) 1.75
Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis. Am J Pathol (2012) 1.37
Obesity and asthma: an inflammatory disease of adipose tissue not the airway. Am J Respir Crit Care Med (2012) 1.28
Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications. Expert Rev Gastroenterol Hepatol (2011) 1.22
Molecular mechanisms of hepatic apoptosis. Cell Death Dis (2014) 1.21
NLRP3 inflammasome activation is required for fibrosis development in NAFLD. J Mol Med (Berl) (2014) 1.13
Consilience in sarcopenia of cirrhosis. J Cachexia Sarcopenia Muscle (2012) 1.08
Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations. World J Gastroenterol (2014) 1.04
Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice. Am J Physiol Gastrointest Liver Physiol (2011) 1.03
The role of Klotho in energy metabolism. Nat Rev Endocrinol (2012) 0.95
Obesity and cancer pathogenesis. Ann N Y Acad Sci (2014) 0.93
Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers. Clin Pharmacokinet (2014) 0.90
Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels. Mol Metab (2014) 0.89
Molecular Interactions between NAFLD and Xenobiotic Metabolism. Front Genet (2013) 0.88
Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats. Int J Mol Sci (2012) 0.88
Interventions to promote an integrated approach to public health problems: an application to childhood obesity. J Environ Public Health (2012) 0.87
Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease. World J Hepatol (2014) 0.87
Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats. PLoS One (2013) 0.85
Insulin resistance and other metabolic risk factors in the pathogenesis of hepatocellular carcinoma. Clin Liver Dis (2011) 0.84
In Acute Myocardial Infarction Liver Parameters Are Associated With Stenosis Diameter. Medicine (Baltimore) (2016) 0.84
Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. Sci Rep (2014) 0.84
Persistent increase in alpha-fetoprotein level in a patient without underlying liver disease who underwent curative resection of hepatocellular carcinoma. A case report and review of the literature. World J Surg Oncol (2012) 0.84
Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. PLoS One (2012) 0.84
A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet. Sci Rep (2016) 0.82
Association of adiponectin with hepatic steatosis: a study of 1,349 subjects in a random population sample. BMC Res Notes (2014) 0.82
Effect of alcohol on adipose tissue: a review on ethanol mediated adipose tissue injury. Adipocyte (2015) 0.81
Impact of anthropometrical parameters on portal vein diameter and liver size in a subset of Karachi based population. Pak J Med Sci (2014) 0.81
Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation. Cell Death Differ (2015) 0.80
Regional variations in the relationship between arterial stiffness and adipocyte volume or number in obese subjects. Int J Obes (Lond) (2014) 0.80
High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma. BMC Gastroenterol (2014) 0.79
Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation. J Am Heart Assoc (2016) 0.79
Macrophage function in obesity-induced inflammation and insulin resistance. Pflugers Arch (2017) 0.78
Diet-induced obesity modulates epigenetic responses to ionizing radiation in mice. PLoS One (2014) 0.78
Meta-omic platforms to assist in the understanding of NAFLD gut microbiota alterations: tools and applications. Int J Mol Sci (2014) 0.78
Diet, obesity, and cancer progression: are adipocytes the link? Lipid Insights (2013) 0.77
Perturbations of lipid metabolism indexed by lipidomic biomarkers. Metabolites (2012) 0.77
Diet containing low n-6/n-3 polyunsaturated fatty acids ratio, provided by canola oil, alters body composition and bone quality in young rats. Eur J Nutr (2011) 0.76
Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.76
The missing link between obesity and hepatocellular carcinoma: IL-6-mediated STAT-3 activation as a key player in hepatocarcinogenesis. Digestion (2011) 0.76
Targeting Cell Death and Sterile Inflammation Loop for the Treatment of Nonalcoholic Steatohepatitis. Semin Liver Dis (2016) 0.76
Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults. Mol Biol Rep (2016) 0.75
Role of n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity-Induced Metabolic Syndrome in Animal Models and Humans. Int J Mol Sci (2016) 0.75
Diagnostic Value of CK-18, FGF-21, and Related Biomarker Panel in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Biomed Res Int (2017) 0.75
Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control. EBioMedicine (2016) 0.75
Distinct Hepatic Macrophage Populations in Lean and Obese Mice. Front Endocrinol (Lausanne) (2016) 0.75
The impact of cortisol in steatotic and non-steatotic liver surgery. J Cell Mol Med (2017) 0.75
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology (2003) 4.84
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study. Lancet Oncol (2012) 3.88
Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet (2005) 3.33
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology (2004) 3.23
Albumin dialysis in cirrhosis with superimposed acute liver injury: a prospective, controlled study. Hepatology (2002) 3.16
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. J Hepatol (2012) 3.04
Low-molecular-weight heparin in patients with advanced cirrhosis. Liver Int (2010) 2.96
Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury. J Hepatol (2010) 2.71
Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival. Hepatology (2010) 2.60
Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure. Gastroenterology (2012) 2.46
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology (2004) 2.33
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J Hepatol (2003) 2.29
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice. Hepatology (2014) 2.22
Biliary complications after liver transplantation: addition of T1-weighted images to MR cholangiopancreatography facilitates detection of cast in biliary cast syndrome. Radiology (2012) 2.01
Aortoesophageal fistula after thoracic aortic stent-graft placement: a rare but catastrophic complication of a novel emerging technique. JACC Cardiovasc Interv (2009) 1.94
Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis. Int J Cancer (2011) 1.89
The interaction of hepatic lipid and glucose metabolism in liver diseases. J Hepatol (2011) 1.87
Aortoesophageal fistula secondary to stent-graft repair of the thoracic aorta. J Endovasc Ther (2004) 1.85
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis. J Biol Chem (2009) 1.82
Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium. Am J Pathol (2002) 1.80
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. Hepatology (2013) 1.78
The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response. Gut (2010) 1.77
From NAFLD to NASH to cirrhosis-new insights into disease mechanisms. Nat Rev Gastroenterol Hepatol (2013) 1.75
Living-related liver transplantation from the view of the donor: a 1-year follow-up survey. Transplantation (2002) 1.66
Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice. Hepatology (2007) 1.59
Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology (2009) 1.59
Endoscopic therapy of posttransplant biliary stenoses after right-sided adult living donor liver transplantation. Clin Gastroenterol Hepatol (2005) 1.58
Biochemical and histological effects of 26 weeks of glycyrrhizin treatment in chronic hepatitis C: a randomized phase II trial. J Hepatol (2006) 1.54
Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion. Mol Cancer (2010) 1.51
Predictors of graft and patient survival in hepatitis C virus (HCV) recipients: model to predict HCV cirrhosis after liver transplantation. Transplantation (2007) 1.51
MR colonography vs. optical colonoscopy: comparison of patients' acceptance in a screening population. Eur Radiol (2007) 1.48
Magnetic endoscopic imaging saves abdominal compression and patient pain in routine colonoscopies. J Dig Dis (2011) 1.47
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency. Gastroenterology (2009) 1.46
Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR. BMC Cancer (2008) 1.44
Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. Transplantation (2015) 1.44
Extrahepatic complications of nonalcoholic fatty liver disease. Hepatology (2014) 1.41
Elevated gamma-glutamyltransferase is associated with mortality in lung transplantation for cystic fibrosis. Transpl Int (2011) 1.39
Serum versus intrahepatic HCV RNA and liver histology. Hepatology (2002) 1.39
Antiviral treatment of chronic hepatitis B with lamivudine in pediatric renal transplantation. Pediatr Transplant (2006) 1.39
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem (2003) 1.32
Right living donor liver transplantation: an option for adult patients: single institution experience with 74 patients. Ann Surg (2003) 1.31
Quantitative liver function tests in donors and recipients of living donor liver transplantation. Liver Transpl (2006) 1.30
Changes in the expression of plasma membrane calcium extrusion systems during the maturation of hippocampal neurons. Hippocampus (2006) 1.29
Increased levels of interleukin-10 in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of circulating dendritic cell subsets. Clin Cancer Res (2004) 1.27
Risk prediction and outcomes in patients with liver cirrhosis undergoing open-heart surgery. Eur J Cardiothorac Surg (2010) 1.25
TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury. J Biol Chem (2009) 1.25
Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver. J Leukoc Biol (2005) 1.24
Volumetric and functional recovery of the liver after right hepatectomy for living donation. Liver Transpl (2004) 1.22
Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation. Hepatology (2010) 1.22
Balloon dilatation vs. balloon dilatation plus bile duct endoprostheses for treatment of anastomotic biliary strictures after liver transplantation. Liver Transpl (2006) 1.22
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology (2009) 1.21
Living donor liver transplantation for hepatocellular carcinoma: a single-center preliminary report. Liver Transpl (2006) 1.20
Hepatitis B virus-induced defect of monocyte-derived dendritic cells leads to impaired T helper type 1 response in vitro: mechanisms for viral immune escape. Immunology (2003) 1.20
Apoptosis versus necrosis rate as a predictor in acute liver failure following acetaminophen intoxication compared with acute-on-chronic liver failure. Liver Int (2008) 1.20
Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines. Gastroenterology (2009) 1.14
NLRP3 inflammasome activation is required for fibrosis development in NAFLD. J Mol Med (Berl) (2014) 1.13
Hepatitis B-associated acute liver failure: immediate treatment with entecavir inhibits hepatitis B virus replication and potentially its sequelae. Digestion (2009) 1.13
Impact of a self-expanding, plastic esophageal stent on various esophageal stenoses, fistulas, and leakages: a single-center experience in 39 patients. Gastrointest Endosc (2005) 1.13
Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis. Liver Int (2010) 1.12
Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication. J Hepatol (2008) 1.11
Recurrent lymphocytic myocarditis in a young male with ulcerative colitis. Eur J Med Res (2014) 1.08
Preoperative assessment of hilar cholangiocarcinoma by dual-modality PET/CT. J Surg Oncol (2008) 1.08
Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther (2002) 1.07
A combination of α-fetoprotein and des-γ-carboxy prothrombin is superior in detection of hepatocellular carcinoma. Digestion (2013) 1.06
Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. J Hepatol (2012) 1.05
Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer. Gastroenterology (2011) 1.05
Major histocompatibility complex class I-related chains A and B (MIC A/B): a novel role in nonalcoholic steatohepatitis. Hepatology (2010) 1.04
Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: therapeutic implications for hepatitis C. J Hepatol (2008) 1.04
Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance. J Immunol (2006) 1.03
Acute liver failure: a life-threatening disease. Dtsch Arztebl Int (2011) 1.03
Etiologies and outcomes of acute liver failure in Germany. Clin Gastroenterol Hepatol (2012) 1.02
Experience after the evaluation of 700 potential donors for living donor liver transplantation in a single center. Liver Transpl (2004) 1.02
Severe acute pancreatitis: nonsurgical treatment of infected necroses. Pancreas (2005) 1.00
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases. World J Gastroenterol (2010) 1.00
Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication. J Hepatol (2009) 1.00
Pulmonary and blood stream infections in adult living donor and cadaveric liver transplant patients. Transplantation (2008) 1.00
Magnetic resonance colonography without bowel cleansing: a prospective cross sectional study in a screening population. Gut (2007) 1.00
Overweight patients are more susceptible for acute liver failure. Hepatogastroenterology (2005) 0.99
Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C. J Hepatol (2007) 0.98
Diagnosis of biliary strictures after liver transplantation: which is the best tool? World J Gastroenterol (2005) 0.98
Comparison of the sixth and the seventh editions of the UICC classification for perihilar cholangiocarcinoma. Ann Surg Oncol (2012) 0.97
Removal of metabolites, cytokines and hepatic growth factors by extracorporeal liver support in children. J Pediatr Gastroenterol Nutr (2005) 0.97
Small bowel homing T cells are associated with symptoms and delayed gastric emptying in functional dyspepsia. Am J Gastroenterol (2011) 0.95