Published in Cell Signal on November 08, 2010
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Targeting the Wnt pathways for therapies. Mol Cell Ther (2014) 0.93
Wnt5a promotes inflammatory responses via nuclear factor κB (NF-κB) and mitogen-activated protein kinase (MAPK) pathways in human dental pulp cells. J Biol Chem (2014) 0.87
Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation (2012) 0.86
Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. J Biol Chem (2015) 0.83
Kermit interacts with Gαo, Vang, and motor proteins in Drosophila planar cell polarity. PLoS One (2013) 0.77
WNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Gα12/13. Mol Pharmacol (2016) 0.75
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell (2012) 2.54
Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature (2008) 2.24
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J Cell Sci (2007) 1.65
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A (2007) 1.46
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc Natl Acad Sci U S A (2005) 1.33
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal (2006) 1.26
CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J Biol Chem (2008) 1.23
Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Mol Cell Biol (2010) 1.19
Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation. PLoS One (2012) 1.18
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation. EMBO J (2011) 1.18
Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. J Neurosci (2004) 1.18
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. PLoS One (2008) 1.14
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proc Natl Acad Sci U S A (2013) 1.12
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep (2008) 1.12
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain (2011) 1.10
Modulation of glial cell functions by adenosine receptors. Physiol Behav (2007) 1.09
Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol Cell Neurosci (2005) 1.09
WNT signaling in activated microglia is proinflammatory. Glia (2010) 1.07
Molecular pathology of the fibroblast growth factor family. Hum Mutat (2009) 1.06
Brain-derived neurotrophic factor controls functional differentiation and microcircuit formation of selectively isolated fast-spiking GABAergic interneurons. Eur J Neurosci (2004) 1.05
FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells. Exp Cell Res (2004) 1.05
Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases. J Biol Chem (2011) 1.04
Vang-like protein 2 and Rac1 interact to regulate adherens junctions. J Cell Sci (2010) 1.02
Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage. PLoS One (2008) 1.02
Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway. Sci Signal (2014) 1.01
Evidence for functional adenosine A3 receptors in microglia cells. J Neurochem (2003) 1.01
Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2. FASEB J (2010) 1.00
Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia. Am J Hum Genet (2011) 1.00
Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway. BMC Cell Biol (2008) 0.98
Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha. Circ Res (2008) 0.97
FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence. Bone (2010) 0.96
SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem Cells (2012) 0.90
NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells. J Biol Chem (2010) 0.89
Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1). J Biol Chem (2011) 0.88
Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC. Eur J Pharmacol (2008) 0.87
Wnt2 regulates progenitor proliferation in the developing ventral midbrain. J Biol Chem (2009) 0.87
Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation (2012) 0.86
WNT-3A and WNT-5A counteract lipopolysaccharide-induced pro-inflammatory changes in mouse primary microglia. J Neurochem (2013) 0.86
The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia. Anesthesiology (2010) 0.85
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. Mol Cell Biol (2012) 0.85
Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. Cell Signal (2008) 0.84
Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3'-kinase. Biochem Pharmacol (2004) 0.83
Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. FASEB J (2014) 0.83
WNT unrelated activities in commercially available preparations of recombinant WNT3a. J Cell Biochem (2010) 0.82
Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells. Biochem Biophys Res Commun (2003) 0.81
PKC 412 sensitizes U1810 non-small cell lung cancer cells to DNA damage. Exp Cell Res (2005) 0.80
Pertussis toxin-sensitive heterotrimeric G(αi/o) proteins mediate WNT/β-catenin and WNT/ERK1/2 signaling in mouse primary microglia stimulated with purified WNT-3A. Cell Signal (2012) 0.79
Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway. Cell Commun Signal (2015) 0.79
β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. J Biol Chem (2013) 0.78
The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells. Biochem Biophys Res Commun (2003) 0.76