Published in Nature on January 09, 2008
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature (2012) 2.73
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GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches. Physiology (Bethesda) (2009) 1.14
Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol (2008) 1.11
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Regulation of boundary cap neural crest stem cell differentiation after transplantation. Stem Cells (2009) 0.94
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BNP signaling is crucial for embryonic stem cell proliferation. PLoS One (2009) 0.90
GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nat Neurosci (2015) 0.89
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GABA regulates the multidirectional tangential migration of GABAergic interneurons in living neonatal mice. PLoS One (2011) 0.86
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Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression. Breast Cancer Res (2009) 0.85
Ion channels in hematopoietic and mesenchymal stem cells. Stem Cells Int (2012) 0.84
GABA regulates stem cell proliferation before nervous system formation. Epilepsy Curr (2008) 0.84
Development of cortical GABAergic innervation. Front Cell Neurosci (2011) 0.83
Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice. PLoS One (2010) 0.83
GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)R Signaling. Front Cell Neurosci (2012) 0.82
α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. Acta Neuropathol (2013) 0.82
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Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models. Front Neural Circuits (2013) 0.81
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ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration. DNA Repair (Amst) (2013) 0.81
Effect of specific activation of γ-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy. Hepatol Res (2012) 0.81
GABA increases Ca2+ in cerebellar granule cell precursors via depolarization: implications for proliferation. IUBMB Life (2009) 0.81
Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease. Int J Mol Sci (2013) 0.80
The p53 co-activator Zac1 neither induces cell cycle arrest nor apoptosis in chicken Lim1 horizontal progenitor cells. Cell Death Discov (2015) 0.80
GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium. PLoS One (2012) 0.80
Phosphorylation of histone H2AX in the mouse brain from development to senescence. Int J Mol Sci (2014) 0.79
Cancer stem cells and cell size: A causal link? Semin Cancer Biol (2015) 0.79
Transcriptional Profiling of Hypoxic Neural Stem Cells Identifies Calcineurin-NFATc4 Signaling as a Major Regulator of Neural Stem Cell Biology. Stem Cell Reports (2015) 0.79
Non-neuronal release of gamma-aminobutyric Acid by embryonic pluripotent stem cells. Stem Cells Dev (2013) 0.78
Novel functions of GABA signaling in adult neurogenesis. Front Biol (Beijing) (2013) 0.78
Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced γH2AX accumulation. EMBO Rep (2015) 0.78
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Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants. Reprod Toxicol (2014) 0.78
The altered expression of α1 and β3 subunits of the gamma-aminobutyric acid A receptor is related to the hepatitis C virus infection. Eur J Clin Microbiol Infect Dis (2011) 0.77
Liver graft pretreated in vivo or ex vivo by γ-aminobutyric acid receptor regulation. J Surg Res (2012) 0.77
A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells. PLoS One (2014) 0.77
Pretreatment of Small-for-Size Grafts In Vivo by γ -Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation. Int J Hepatol (2013) 0.77
A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation. Cell Mol Life Sci (2015) 0.76
Pretreatment of liver grafts in vivo by γ-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat. Ann Transplant (2013) 0.76
DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment. Oncogene (2015) 0.76
Ion channel activities in neural stem cells of the neuroepithelium. Stem Cells Int (2012) 0.76
Ketamine exposure in early development impairs specification of the primary germ cell layers. Neurotoxicol Teratol (2014) 0.76
Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels. BMC Dev Biol (2017) 0.75
Autocrine glutamatergic transmission for the regulation of embryonal carcinoma stem cells. Oncotarget (2016) 0.75
Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. PLoS One (2013) 0.75
A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma. Acta Neuropathol (2016) 0.75
Glutamate Decarboxylase 1 Overexpression as a Poor Prognostic Factor in Patients with Nasopharyngeal Carcinoma. J Cancer (2016) 0.75
To go or not to go? Cell Cycle (2015) 0.75
Neurotransmitter-Regulated Regeneration in the Zebrafish Retina. Stem Cell Reports (2017) 0.75
Sodium valproate enhances urethane tumorigenicity in lungs of male but not female mice. EXCLI J (2014) 0.75
A miRNAs panel promotes the proliferation and invasion of colorectal cancer cells by targeting GABBR1. Cancer Med (2016) 0.75
ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent manner. Springerplus (2016) 0.75
Effect of midazolam on the proliferation of neural stem cells isolated from rat hippocampus. Neural Regen Res (2012) 0.75
γ-Aminobutyric A receptor (GABA(A)R) regulates aquaporin 4 expression in the subependymal zone: relevance to neural precursors and water exchange. J Biol Chem (2014) 0.75
Sodium Valproate Enhances the Urethane-Induced Lung Adenomas and Suppresses Malignization of Adenomas in Ovariectomized Female Mice. Int J Endocrinol (2015) 0.75
Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation. Cell Rep (2016) 0.75
An autocrine γ-aminobutyric acid signaling system exists in pancreatic β-cell progenitors of fetal and postnatal mice. Int J Physiol Pathophysiol Pharmacol (2013) 0.75
The effects of etomidate and midazolam on adipose tissue-derived mesenchymal stem cell proliferation. Korean J Anesthesiol (2016) 0.75
Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons. Mol Cell Neurosci (2010) 0.75
Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Rep (2014) 0.75
Valerian inhibits rat hepatocarcinogenesis by activating GABA(A) receptor-mediated signaling. PLoS One (2014) 0.75
Phenotypic Screening Identifies Synergistically Acting Natural Product Enhancing the Performance of Biomaterial Based Wound Healing. Front Pharmacol (2017) 0.75
Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq. Genome Res (2011) 6.90
Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (2002) 5.08
Temporal difference models describe higher-order learning in humans. Nature (2004) 4.94
Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons. J Neurosci (2010) 3.61
Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons. Dev Neurobiol (2011) 3.50
Axoplasmic importins enable retrograde injury signaling in lesioned nerve. Neuron (2003) 3.40
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell (2006) 3.12
Opponent appetitive-aversive neural processes underlie predictive learning of pain relief. Nat Neurosci (2005) 3.05
Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci (2005) 3.02
Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci (2009) 2.69
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci (2003) 2.66
Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex (2009) 2.61
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell (2012) 2.54
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin. Cell (2009) 2.53
The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors. J Neurosci (2010) 2.50
Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. J Cell Biol (2003) 2.47
Noninvasive in vivo imaging of pancreatic islet cell biology. Nat Med (2008) 2.41
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron (2008) 2.33
Specification and connectivity of neuronal subtypes in the sensory lineage. Nat Rev Neurosci (2007) 2.28
Nociceptors lacking TRPV1 and TRPV2 have normal heat responses. J Neurosci (2004) 2.24
Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3. Science (2002) 2.24
Highly multiplexed and strand-specific single-cell RNA 5' end sequencing. Nat Protoc (2012) 2.21
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A (2003) 2.14
Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma. BMC Genomics (2006) 2.04
Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS. Nat Neurosci (2004) 2.01
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression. J Neurosci (2007) 1.87
Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions. Curr Biol (2010) 1.86
Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell (2009) 1.84
The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons. Nat Neurosci (2006) 1.83
Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling. Cell (2007) 1.82
A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (2006) 1.79
Derivation of mouse embryonic stem cells. Nat Protoc (2006) 1.76
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. J Neurosci (2004) 1.76
Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells. Eur J Immunol (2013) 1.76
ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors. Mol Pharmacol (2008) 1.72
Decoding the rules of recruitment of excitatory interneurons in the adult zebrafish locomotor network. Proc Natl Acad Sci U S A (2012) 1.70
Brain damage after coronary artery bypass grafting. Arch Neurol (2002) 1.67
The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron (2009) 1.66
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J Cell Sci (2007) 1.65
Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex. Nat Neurosci (2009) 1.64
Molecular mechanisms of cancer pain. Nat Rev Cancer (2002) 1.62
Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons. Development (2006) 1.58
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.57
Control of myelination in Schwann cells: a Krox20 cis-regulatory element integrates Oct6, Brn2 and Sox10 activities. EMBO Rep (2006) 1.56
Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest (2014) 1.55
BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Development (2003) 1.54
Many cold sensitive peripheral neurons of the mouse do not express TRPM8 or TRPA1. Cell Calcium (2006) 1.54
Peripheral myelin maintenance is a dynamic process requiring constant Krox20 expression. J Neurosci (2006) 1.52
L-2-Hydroxyglutaric aciduria: identification of a mutant gene C14orf160, localized on chromosome 14q22.1. Hum Mol Genet (2004) 1.50
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A (2007) 1.46
Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. Stem Cells (2010) 1.44
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J (2003) 1.44
Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells. Proc Natl Acad Sci U S A (2011) 1.41
Peripheral nerve damage associated with administration of taxanes in patients with cancer. Crit Rev Oncol Hematol (2008) 1.40
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development (2012) 1.37
Chemotherapy-induced peripheral neurotoxicity: a critical analysis. CA Cancer J Clin (2014) 1.36
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. J Neurosci (2007) 1.34
Ebf gene function is required for coupling neuronal differentiation and cell cycle exit. Development (2003) 1.34
Characterisation of cis-acting sequences reveals a biphasic, axon-dependent regulation of Krox20 during Schwann cell development. Development (2002) 1.33
Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc Natl Acad Sci U S A (2005) 1.33
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proc Natl Acad Sci U S A (2010) 1.31
Molecular interactions underlying the specification of sensory neurons. Trends Neurosci (2012) 1.30
Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest (2008) 1.29
TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception. J Neurosci (2011) 1.28
Hoxa2- and rhombomere-dependent development of the mouse facial somatosensory map. Science (2006) 1.27
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal (2006) 1.26
Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci (2010) 1.26
Antagonism of nerve growth factor-TrkA signaling and the relief of pain. Anesthesiology (2011) 1.25
New moves in motor control. Curr Biol (2011) 1.24
Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. J Neurochem (2005) 1.24
GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons. J Cell Sci (2004) 1.24
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? J Biol Chem (2009) 1.23
CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J Biol Chem (2008) 1.23
The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. Mol Biol Cell (2008) 1.23
An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Dis Model Mech (2009) 1.22
An efficient method for the derivation of mouse embryonic stem cells. Stem Cells (2005) 1.20
Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points. Neuron (2003) 1.19
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Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation. PLoS One (2012) 1.18
Modulation of pain processing in hyperalgesia by cognitive demand. Neuroimage (2005) 1.18
Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3. J Neurosci (2004) 1.18
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation. EMBO J (2011) 1.18
Wnt5a regulates midbrain dopaminergic axon growth and guidance. PLoS One (2011) 1.18
BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development. Development (2003) 1.18
The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes. Development (2005) 1.17
Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. Eur J Neurosci (2006) 1.14
Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. PLoS One (2008) 1.14
Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev (2003) 1.13
The p75 neurotrophin receptor interacts with multiple MAGE proteins. J Biol Chem (2002) 1.13
Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep (2008) 1.12
In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells. Exp Neurol (2006) 1.12
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proc Natl Acad Sci U S A (2013) 1.12