Published in Dev Cell on November 16, 2010
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat Immunol (2013) 1.28
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages. Elife (2014) 0.90
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Uncovering the link between malfunctions in Drosophila neuroblast asymmetric cell division and tumorigenesis. Cell Biosci (2012) 0.76
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Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet (2005) 3.99
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila. Science (2010) 3.21
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Science (2007) 2.97
Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet (2009) 2.93
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes Dev (2006) 2.06
A small peptide mimicking the key domain of MEPE/OF45 interacting with CHK1 protects human cells from radiation-induced killing. Cell Cycle (2010) 2.06
Biochemical evidence for Ku-independent backup pathways of NHEJ. Nucleic Acids Res (2003) 2.05
Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila. Curr Biol (2007) 1.99
Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system. Mol Ther (2011) 1.96
Computer-aided design of a PDZ domain to recognize new target sequences. Nat Struct Biol (2002) 1.89
A genome-wide search for signals of high-altitude adaptation in Tibetans. Mol Biol Evol (2010) 1.86
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon. Nature (2007) 1.83
Lats2, a putative tumor suppressor, inhibits G1/S transition. Oncogene (2003) 1.82
Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesion. Dev Cell (2005) 1.73
Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins. Nat Cell Biol (2005) 1.72
Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis. J Cell Biol (2008) 1.70
Neurogenesis and asymmetric cell division. Curr Opin Neurobiol (2008) 1.65
Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. Curr Biol (2008) 1.64
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nat Genet (2009) 1.62
Drosophila neuroblasts retain the daughter centrosome. Nat Commun (2011) 1.59
Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell (2003) 1.57
Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia. Blood (2012) 1.51
Calcitriol restores renovascular function in estrogen-deficient rats through downregulation of cyclooxygenase-2 and the thromboxane-prostanoid receptor. Kidney Int (2013) 1.49
Contribution of noncentrosomal microtubules to spindle assembly in Drosophila spermatocytes. PLoS Biol (2004) 1.48
Mutations in TUBB8 and Human Oocyte Meiotic Arrest. N Engl J Med (2016) 1.46
The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe. J Cell Sci (2004) 1.45
A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning. Nat Neurosci (2009) 1.38
Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. J Cell Biol (2003) 1.33
RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia. Blood (2012) 1.33
Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development (2002) 1.31
Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia. Clin Cancer Res (2013) 1.30
T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes. Immunity (2010) 1.29
Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities. J Neurosci (2007) 1.26
Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs. Free Radic Biol Med (2011) 1.23
NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. Cell Res (2012) 1.21
Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression. Mol Biol Cell (2003) 1.19
An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R. J Exp Med (2005) 1.18
Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease. J Neurosci (2008) 1.17
The interphase microtubule aster is a determinant of asymmetric division orientation in Drosophila neuroblasts. J Cell Biol (2010) 1.17
Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. Genes Dev (2005) 1.15
CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity. Cell Cycle (2002) 1.15
An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts. Dev Cell (2011) 1.13
Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia. Mol Pharmacol (2004) 1.13
A positive feedback loop between Dumbfounded and Rolling pebbles leads to myotube enlargement in Drosophila. J Cell Biol (2005) 1.12
Biased segregation of DNA and centrosomes: moving together or drifting apart? Nat Rev Mol Cell Biol (2009) 1.11
Fhit and CHK1 have opposing effects on homologous recombination repair. Cancer Res (2005) 1.11
The localization of the integral membrane protein Cps1p to the cell division site is dependent on the actomyosin ring and the septation-inducing network in Schizosaccharomyces pombe. Mol Biol Cell (2002) 1.10
Radiosensitizing effects of ectopic miR-101 on non-small-cell lung cancer cells depend on the endogenous miR-101 level. Int J Radiat Oncol Biol Phys (2011) 1.10
Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions. Genes Dev (2009) 1.09
A construct with fluorescent indicators for conditional expression of miRNA. BMC Biotechnol (2008) 1.08
Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2014) 1.08
Integrin signalling and function in immune cells. Immunology (2012) 1.07
Bis{1-[(4-methyl-phen-yl)imino-meth-yl]-2-naphtho-lato-κN,O}copper(II). Acta Crystallogr Sect E Struct Rep Online (2010) 1.07
Localized transfection on arrays of magnetic beads coated with PCR products. Nat Methods (2005) 1.06
The paradox of functional heterochromatin. Bioessays (2005) 1.04
Roles of Bifocal, Homer, and F-actin in anchoring Oskar to the posterior cortex of Drosophila oocytes. Genes Dev (2004) 1.04
Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts. EMBO J (2006) 1.04
High proportion of 22q13 deletions and SHANK3 mutations in Chinese patients with intellectual disability. PLoS One (2012) 1.01
Connecting cancer to the asymmetric division of stem cells. Cell (2006) 1.00
The Drosophila HMG-domain proteins SoxNeuro and Dichaete direct trichome formation via the activation of shavenbaby and the restriction of Wingless pathway activity. Development (2007) 1.00
Tissue culture-induced transpositional activity of mPing is correlated with cytosine methylation in rice. BMC Plant Biol (2009) 1.00
Modulation of DNA methylation by a sesquiterpene lactone parthenolide. J Pharmacol Exp Ther (2009) 0.99
Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells. Development (2009) 0.99
Intrinsic epigenetic factors cooperate with the steroid hormone ecdysone to govern dendrite pruning in Drosophila. Neuron (2011) 0.98
Muscle wasted: a novel component of the Drosophila histone locus body required for muscle integrity. J Cell Sci (2010) 0.98
Spindle alignment is achieved without rotation after the first cell cycle in Drosophila embryonic neuroblasts. Development (2009) 0.98
Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes. J Cell Sci (2003) 0.98
Membrane targeting and asymmetric localization of Drosophila partner of inscuteable are discrete steps controlled by distinct regions of the protein. Mol Cell Biol (2002) 0.97
Silencing MTA1 by RNAi reverses adhesion, migration and invasiveness of cervical cancer cells (SiHa) via altered expression of p53, and E-cadherin/β-catenin complex. J Huazhong Univ Sci Technolog Med Sci (2011) 0.97
A newly identified 191A/C mutation in the Rv2629 gene that was significantly associated with rifampin resistance in Mycobacterium tuberculosis. J Proteome Res (2007) 0.96
Loss of E-cadherin promotes prostate cancer metastasis via upregulation of metastasis-associated gene 1 expression. Oncol Lett (2012) 0.96
Motility screen identifies Drosophila IGF-II mRNA-binding protein--zipcode-binding protein acting in oogenesis and synaptogenesis. PLoS Genet (2008) 0.95
Neural stem cells: the need for a proper orientation. Curr Opin Genet Dev (2010) 0.95
Drosophila T box proteins break the symmetry of hedgehog-dependent activation of wingless. Curr Biol (2004) 0.94
On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN. Open Biol (2012) 0.94
FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements. Chromosoma (2003) 0.94
The Drosophila EAST protein associates with a nuclear remnant during mitosis and constrains chromosome mobility. J Cell Sci (2003) 0.93
Modulation of caspase activity regulates skeletal muscle regeneration and function in response to vasopressin and tumor necrosis factor. PLoS One (2009) 0.93
CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase. J Immunol (2007) 0.93
MicroRNA-21 is involved in ionizing radiation-promoted liver carcinogenesis. Int J Clin Exp Med (2010) 0.93
A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts. J Cell Sci (2003) 0.92
The superior turbinate as a source of functional human olfactory receptor neurons. Laryngoscope (2002) 0.92
Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome. Development (2007) 0.92
Recombinant BCG coexpressing Ag85B, ESAT-6 and mouse-IFN-gamma confers effective protection against Mycobacterium tuberculosis in C57BL/6 mice. FEMS Immunol Med Microbiol (2007) 0.91
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer (2012) 0.91
MEPE/OF45 protects cells from DNA damage induced killing via stabilizing CHK1. Nucleic Acids Res (2009) 0.91
Nortriptyline protects mitochondria and reduces cerebral ischemia/hypoxia injury. Stroke (2008) 0.91
Identification of functional mutations in GATA4 in patients with congenital heart disease. PLoS One (2013) 0.91
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages. Elife (2014) 0.90
Identification of a tumor-suppressive human-specific microRNA within the FHIT tumor-suppressor gene. Cancer Res (2014) 0.90
The genetic epidemiology of psoriasis vulgaris in Chinese Han. Int J Dermatol (2002) 0.90
Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks. Oncogene (2004) 0.89