PubRank

Kenneth M Murphy

Author PubWeight™ 218.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 30.22
2 Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 2006 10.53
3 Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 2008 7.87
4 T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells. Nat Immunol 2002 7.28
5 A validated regulatory network for Th17 cell specification. Cell 2012 4.82
6 Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells. J Exp Med 2010 4.56
7 BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol 2003 4.56
8 Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. J Exp Med 2011 4.02
9 Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med 2011 3.85
10 The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature 2009 3.75
11 B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nat Immunol 2004 3.49
12 The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat Immunol 2011 3.21
13 Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity 2012 3.18
14 A distal conserved sequence element controls Ifng gene expression by T cells and NK cells. Immunity 2006 3.16
15 Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 2003 2.83
16 Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development 2006 2.82
17 Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med 2012 2.74
18 Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose. Immunity 2009 2.61
19 ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature 2005 2.58
20 Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002 2.54
21 CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity 2011 2.50
22 Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell 2008 2.46
23 A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science 2012 2.30
24 Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature 2012 2.25
25 Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature 2008 2.18
26 Re(de)fining the dendritic cell lineage. Nat Immunol 2012 2.17
27 BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 2012 2.00
28 CD8α(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. Immunity 2011 1.99
29 CX3CR1+ CD8alpha+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells. Proc Natl Acad Sci U S A 2010 1.94
30 Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol 2013 1.87
31 Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity 2013 1.81
32 B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells. J Immunol 2005 1.78
33 Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. Proc Natl Acad Sci U S A 2005 1.76
34 Slow down and survive: Enigmatic immunoregulation by BTLA and HVEM. Annu Rev Immunol 2010 1.73
35 CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms. Nat Immunol 2009 1.70
36 Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells. J Exp Med 2009 1.67
37 A crucial role for HVEM and BTLA in preventing intestinal inflammation. J Exp Med 2008 1.67
38 From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce T(H)1 development. Nat Immunol 2009 1.61
39 Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. J Clin Invest 2012 1.57
40 DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues. Blood 2012 1.56
41 Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS One 2008 1.56
42 Differential effects of B and T lymphocyte attenuator and programmed death-1 on acceptance of partially versus fully MHC-mismatched cardiac allografts. J Immunol 2005 1.55
43 Batf3-dependent dendritic cells in the renal lymph node induce tolerance against circulating antigens. J Am Soc Nephrol 2013 1.54
44 BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice. J Leukoc Biol 2009 1.53
45 N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation. Nat Immunol 2004 1.51
46 Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation. Nat Immunol 2008 1.51
47 Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks. Nat Rev Immunol 2013 1.50
48 Unconventional ligand activation of herpesvirus entry mediator signals cell survival. Proc Natl Acad Sci U S A 2009 1.49
49 Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human. J Immunol 2002 1.40
50 Evidence for carbohydrate recognition and homotypic and heterotypic binding by the TIM family. Int Immunol 2007 1.37
51 Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation. J Immunol 2006 1.35
52 Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation. J Immunol 2007 1.30
53 Competition for cytokines: T(reg) cells take all. Nat Immunol 2007 1.30
54 A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection. PLoS Pathog 2011 1.26
55 Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. PLoS One 2011 1.25
56 Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2. Biochem Biophys Res Commun 2003 1.24
57 The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells. J Immunol 2008 1.23
58 B and T lymphocyte attenuator tempers early infection immunity. J Immunol 2009 1.18
59 Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator. Arthritis Rheum 2008 1.18
60 Issues in T-helper 1 development--resolved and unresolved. Immunol Rev 2004 1.17
61 Selective requirement of p38alpha MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses. J Immunol 2006 1.16
62 Regulatory T cell expression of herpesvirus entry mediator suppresses the function of B and T lymphocyte attenuator-positive effector T cells. J Immunol 2008 1.15
63 T helper subset development: roles of instruction, selection, and transcription. J Clin Invest 2002 1.14
64 Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation. Eur J Immunol 2011 1.12
65 PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. J Biol Chem 2003 1.12
66 Effects of ETV5 (ets variant gene 5) on testis and body growth, time course of spermatogonial stem cell loss, and fertility in mice. Biol Reprod 2007 1.12
67 Mechanistic insights into the regulation of the spermatogonial stem cell niche. Cell Cycle 2006 1.12
68 T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. J Immunol 2009 1.11
69 Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells 2011 1.11
70 Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation. Blood 2005 1.10
71 Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA. Biochem Biophys Res Commun 2006 1.09
72 CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNgamma. Virology 2005 1.07
73 Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator. J Immunol 2008 1.06
74 Loss of Etv5 decreases proliferation and RET levels in neonatal mouse testicular germ cells and causes an abnormal first wave of spermatogenesis. Biol Reprod 2009 1.05
75 Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins. J Immunol 2010 1.04
76 Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression. J Exp Med 2010 1.03
77 Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha. J Immunol 2006 1.03
78 Transcription factor networks in dendritic cell development. Semin Immunol 2011 1.03
79 Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance. Exp Cell Res 2007 0.99
80 ETV5 regulates sertoli cell chemokines involved in mouse stem/progenitor spermatogonia maintenance. Stem Cells 2010 0.98
81 Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod 2009 0.96
82 CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA. PLoS One 2013 0.96
83 B and T lymphocyte attenuator regulates T cell survival in the lung. J Immunol 2008 0.95
84 Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization. J Immunol 2010 0.94
85 The central role of the Th17 lineage in regulating the inflammatory/autoimmune axis. Semin Immunol 2008 0.94
86 B and T lymphocyte attenuator restricts the protective immune response against experimental malaria. J Immunol 2011 0.94
87 Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria. J Immunol 2007 0.93
88 Frontline: absence of functional STAT4 activation despite detectable tyrosine phosphorylation induced by murine IFN-alpha. Eur J Immunol 2004 0.92
89 ETV5 is required for continuous spermatogenesis in adult mice and may mediate blood testes barrier function and testicular immune privilege. Ann N Y Acad Sci 2007 0.91
90 Snail promotes the cell-autonomous generation of Flk1(+) endothelial cells through the repression of the microRNA-200 family. Stem Cells Dev 2011 0.91
91 Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3(-/-) mice. Mol Immunol 2011 0.91
92 BTLA and HVEM cross talk regulates inhibition and costimulation. Adv Immunol 2006 0.91
93 IL-12, but not IFN-alpha, promotes STAT4 activation and Th1 development in murine CD4+ T cells expressing a chimeric murine/human Stat2 gene. J Immunol 2005 0.89
94 Origin, development, and homeostasis of tissue-resident macrophages. Immunol Rev 2014 0.88
95 Cross-presenting dendritic cells are required for control of Leishmania major infection. Eur J Immunol 2014 0.87
96 Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination. Proc Natl Acad Sci U S A 2012 0.87
97 Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation. Blood 2012 0.87
98 Activation-induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells. J Leukoc Biol 2009 0.86
99 T-cell subsets: the more the merrier. Curr Biol 2007 0.84
100 CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection. J Exp Med 2014 0.84
101 MHC class I cross-presentation by dendritic cells counteracts viral immune evasion. Front Immunol 2012 0.83
102 Host-derived CD8+ dendritic cells are required for induction of optimal graft-versus-tumor responses after experimental allogeneic bone marrow transplantation. Blood 2013 0.83
103 Complex ovarian defects lead to infertility in Etv5-/- female mice. Mol Hum Reprod 2011 0.83
104 Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS One 2013 0.82
105 The role of co-inhibitory signals in spontaneous tolerance of weakly mismatched transplants. Immunobiology 2011 0.82
106 Negative and positive co-signaling with anti-BTLA (PJ196) and CTLA4Ig prolongs islet allograft survival. Transplantation 2007 0.81
107 Pillars article: development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. 1993. Science 260(5107): 547-549. J Immunol 2008 0.79
108 Therapeutic potential of B and T lymphocyte attenuator expressed on CD8+ T cells for contact hypersensitivity. J Invest Dermatol 2012 0.79
109 In search of the CTD. Nat Immunol 2003 0.78
110 Stress management for T helper differentiation. Nat Immunol 2006 0.75
111 Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nat Commun 2017 0.75