Published in J Immunol on May 01, 1990
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway. J Exp Med (1992) 2.71
Diphosphoryl lipid A obtained from the nontoxic lipopolysaccharide of Rhodopseudomonas sphaeroides is an endotoxin antagonist in mice. Infect Immun (1991) 1.46
Shiga toxin-associated hemolytic uremic syndrome: combined cytotoxic effects of shiga toxin and lipopolysaccharide (endotoxin) on human vascular endothelial cells in vitro. Infect Immun (1992) 1.38
Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells. Proc Natl Acad Sci U S A (1993) 1.32
Cyanobacterial lipopolysaccharides and human health - a review. Environ Health (2006) 1.12
Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14. Infect Immun (1995) 1.09
Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells. Infect Immun (1991) 1.06
Enzymatically deacylated Neisseria lipopolysaccharide (LPS) inhibits murine splenocyte mitogenesis induced by LPS. Infect Immun (1991) 1.03
In vivo inhibition of lipopolysaccharide-induced lethality and tumor necrosis factor synthesis by Rhodobacter sphaeroides diphosphoryl lipid A is dependent on corticosterone induction. Infect Immun (1992) 1.00
Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells. J Exp Med (2003) 0.99
From agonist to antagonist: structure and dynamics of innate immune glycoprotein MD-2 upon recognition of variably acylated bacterial endotoxins. Mol Immunol (2011) 0.97
Anti-endotoxin therapy in primate bacteremia with HA-1A and BPI. Ann Surg (1994) 0.93
Adenovirus-mediated transfer of a gene encoding acyloxyacyl hydrolase (AOAH) into mice increases tissue and plasma AOAH activity. Infect Immun (1996) 0.87
Chapter 2: Kill the bacteria...and also their messengers? Adv Immunol (2009) 0.84
Deacylation of purified lipopolysaccharides by cellular and extracellular components of a sterile rabbit peritoneal inflammatory exudate. Infect Immun (1999) 0.83
Lipopolysaccharide augments HLA-A,B,C molecule expression but inhibits interferon-gamma-induced HLA-DR molecule expression on cultured human endothelial cells. Immunology (1991) 0.81
Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury. Toxicology (2011) 0.80
PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell (1999) 10.08
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest (1993) 9.56
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc Natl Acad Sci U S A (1991) 5.60
Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor. Science (1994) 4.84
Size heterogeneity of Salmonella typhimurium lipopolysaccharides in outer membranes and culture supernatant membrane fragments. J Bacteriol (1980) 4.84
MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell (1997) 4.67
Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol (1994) 4.65
Anti-endotoxin monoclonal antibodies. N Engl J Med (1992) 4.39
Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ Res (2001) 4.38
Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc Natl Acad Sci U S A (1999) 4.11
Signaling pathways for cardiac hypertrophy and failure. N Engl J Med (1999) 3.97
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc Natl Acad Sci U S A (1993) 3.92
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem (1998) 3.80
Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell (1999) 3.76
Pre-arrest morbidity and other correlates of survival after in-hospital cardiopulmonary arrest. Am J Med (1989) 3.66
T antigen and template requirements for SV40 DNA replication in vitro. EMBO J (1985) 3.59
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev (1994) 3.54
Transthoracic echocardiography in models of cardiac disease in the mouse. Circulation (1996) 3.34
A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Cell (2001) 3.13
Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci U S A (1998) 3.05
Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development (1998) 2.91
New host cell system for regulated simian virus 40 DNA replication. Mol Cell Biol (1985) 2.82
Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution. Structure (1994) 2.80
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci U S A (2001) 2.77
Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci U S A (1998) 2.76
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway. J Exp Med (1992) 2.71
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell (1999) 2.68
Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res (2000) 2.67
Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. J Biol Chem (1990) 2.64
Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli. J Virol (1994) 2.56
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med (1998) 2.54
Prevention of venous thromboembolism in general surgical patients. Results of meta-analysis. Ann Surg (1988) 2.52
Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes. Nat Med (2001) 2.40
Development of childhood allergy in infants fed breast, soy, or cow milk. J Allergy Clin Immunol (1973) 2.38
Structural basis of latency in plasminogen activator inhibitor-1. Nature (1992) 2.33
Spread of meningococcal infection within households. Lancet (1974) 2.32
Fashioning the vertebrate heart: earliest embryonic decisions. Development (1997) 2.29
Statins and the acute-phase response. N Engl J Med (2001) 2.28
Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia. Am J Pathol (1981) 2.28
Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice. J Biol Chem (1995) 2.27
Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism. J Biol Chem (1992) 2.19
Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. Am J Physiol (1999) 2.12
Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci U S A (1995) 2.11
Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells. J Biol Chem (1998) 2.05
Selective requirement of myosin light chain 2v in embryonic heart function. J Biol Chem (1998) 2.05
Biological activity, lipoprotein-binding behavior, and in vivo disposition of extracted and native forms of Salmonella typhimurium lipopolysaccharides. J Clin Invest (1982) 2.01
Deacylated lipopolysaccharide inhibits neutrophil adherence to endothelium induced by lipopolysaccharide in vitro. J Exp Med (1987) 2.01
Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation (1997) 2.00
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. N Engl J Med (1981) 2.00
Anomalous origin of the left circumflex coronary artery. Recognition, antiographic demonstration and clinical significance. Circulation (1974) 1.97
Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J Biol Chem (1994) 1.96
Detoxification of bacterial lipopolysaccharides (endotoxins) by a human neutrophil enzyme. Science (1986) 1.94
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94
Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice. Circulation (1997) 1.91
HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. J Biol Chem (1993) 1.91
A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells. Mol Cell Biol (1991) 1.88
Randomized clinical trial comparing surgery with conservative treatment for uncomplicated varicose veins. Br J Surg (2006) 1.87
Epidemic disease due to serogroup C Neisseria meningitidis in Saõ Paulo, Brazil. J Infect Dis (1974) 1.85
Epidemiologic studies of serotype antigens common to groups B and C Neisseria meningitidis. J Infect Dis (1975) 1.84
CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development (1997) 1.83
Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure. J Clin Invest (1999) 1.82
Sites of tissue binding and uptake in vivo of bacterial lipopolysaccharide-high density lipoprotein complexes: studies in the rat and squirrel monkey. J Clin Invest (1981) 1.81
Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen. J Biol Chem (1988) 1.81
Heart myosin light chain 2 gene. Nucleotide sequence of full length cDNA and expression in normal and hypertensive rat. J Biol Chem (1986) 1.80
The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. J Biol Chem (1997) 1.80
Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy. J Biol Chem (1997) 1.78
Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube. Proc Natl Acad Sci U S A (1993) 1.76
Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver. Mol Cell Biol (2000) 1.76
Proposed cutoff values to define bladder outlet obstruction in women. Urology (1998) 1.76
Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J Vasc Res (1995) 1.76
Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone. Circ Res (1999) 1.75
Lower limb amputation: striking the balance. Ann R Coll Surg Engl (1994) 1.74
Enzymatic deacylation of the lipid A moiety of Salmonella typhimurium lipopolysaccharides by human neutrophils. Proc Natl Acad Sci U S A (1983) 1.71
Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem (1996) 1.69
Alpha 1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells. Effects on myosin light chain-2 gene expression. J Biol Chem (1988) 1.69
Human disease caused by Brucella canis. A clinical and epidemiologic study of two cases. JAMA (1975) 1.69
Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. J Neurochem (1997) 1.68
Structure, organization, and expression of the rat cardiac myosin light chain-2 gene. Identification of a 250-base pair fragment which confers cardiac-specific expression. J Biol Chem (1989) 1.68
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. J Biol Chem (1993) 1.68
Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J Pharmacol Exp Ther (1999) 1.67
The pharmacologic alteration of renin release. Pharmacol Rev (1980) 1.65
Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury. J Biol Chem (1978) 1.64
The management of short saphenous varicose veins: a survey of the members of the vascular surgical society of Great Britain and Ireland. Eur J Vasc Endovasc Surg (2004) 1.63
DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. J Biol Chem (1999) 1.62
Serpin-resistant mutants of human tissue-type plasminogen activator. Nature (1989) 1.61
A ubiquitous factor (HF-1a) and a distinct muscle factor (HF-1b/MEF-2) form an E-box-independent pathway for cardiac muscle gene expression. Mol Cell Biol (1992) 1.61
Molecular and physiological alterations in murine ventricular dysfunction. Proc Natl Acad Sci U S A (1994) 1.59
Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol (1994) 1.57
Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. Biochim Biophys Acta (1995) 1.57
Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease. Blood (1998) 1.57
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice. Proc Natl Acad Sci U S A (1995) 1.56
Correlation of interleukin-1 beta and cachectin concentrations in cerebrospinal fluid and outcome from bacterial meningitis. J Pediatr (1989) 1.56
Enzymatically deacylated lipopolysaccharide (LPS) can antagonize LPS at multiple sites in the LPS recognition pathway. J Biol Chem (1995) 1.56
Binding of Salmonella typhimurium lipopolysaccharides to rat high-density lipoproteins. Infect Immun (1981) 1.55
Accumulation of unesterified arachidonic acid in ischemic canine myocardium. Relationship to a phosphatidylcholine deacylation-reacylation cycle and the depletion of membrane phospholipids. Circ Res (1984) 1.55
Quality of life following surgery for abdominal aortic aneurysm. Br J Surg (1992) 1.55
Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein. Circ Res (1997) 1.53