Lyle J Palmer

Author PubWeight™ 276.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
2 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 20.01
3 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
4 Replicating genotype-phenotype associations. Nature 2007 16.11
5 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
6 Population stratification and spurious allelic association. Lancet 2003 10.53
7 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
8 Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet 2009 6.83
9 C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet 2005 5.51
10 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 2013 4.71
11 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
12 Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet 2006 4.13
13 Genome-wide association study identifies five loci associated with lung function. Nat Genet 2009 4.10
14 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
15 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet 2010 3.37
16 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
17 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
18 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011 3.03
19 Genetic epidemiology and public health: hope, hype, and future prospects. Lancet 2005 3.00
20 Role of prostanoid DP receptor variants in susceptibility to asthma. N Engl J Med 2004 2.86
21 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
22 FTO genotype is associated with phenotypic variability of body mass index. Nature 2012 2.77
23 A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet 2012 2.60
24 Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies. Int J Epidemiol 2010 2.44
25 Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 2010 2.30
26 Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking. Am J Respir Crit Care Med 2004 2.27
27 Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet 2002 2.23
28 The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet 2004 2.19
29 Association between osteopontin and human abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 2006 2.14
30 Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum Mol Genet 2004 2.14
31 Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med 2011 2.07
32 Transforming growth factor-beta1 promoter polymorphism C-509T is associated with asthma. Am J Respir Crit Care Med 2003 1.98
33 Diminished lipoxin biosynthesis in severe asthma. Am J Respir Crit Care Med 2005 1.87
34 Endothelial nitric oxide synthase variants in cystic fibrosis lung disease. Am J Respir Crit Care Med 2002 1.87
35 Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet 2011 1.82
36 Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 2003 1.74
37 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
38 Toward a roadmap in global biobanking for health. Eur J Hum Genet 2012 1.65
39 Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease. Immunol Rev 2002 1.65
40 Fine mapping versus replication in whole-genome association studies. Am J Hum Genet 2007 1.64
41 Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet 2011 1.60
42 The relationship between infant airway function, childhood airway responsiveness, and asthma. Am J Respir Crit Care Med 2004 1.58
43 Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. PLoS One 2013 1.55
44 JLIN: a java based linkage disequilibrium plotter. BMC Bioinformatics 2006 1.51
45 Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet 2012 1.51
46 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med 2012 1.49
47 Analyses of associations with asthma in four asthma population samples from Canada and Australia. Hum Genet 2009 1.48
48 Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes 2012 1.42
49 Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes. Hum Mol Genet 2002 1.36
50 Sex differences in the association of regional fat distribution with the severity of obstructive sleep apnea. Sleep 2010 1.34
51 Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) 2007 1.32
52 Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetes 2011 1.31
53 The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants. PLoS One 2008 1.28
54 Sequence variants in three loci influence monocyte counts and erythrocyte volume. Am J Hum Genet 2009 1.28
55 Asthma and genes encoding components of the vitamin D pathway. Respir Res 2009 1.26
56 Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Respir Crit Care Med 2002 1.22
57 Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation 2009 1.20
58 Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Hum Mol Genet 2013 1.19
59 Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung. Am J Respir Cell Mol Biol 2002 1.16
60 A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One 2011 1.13
61 Loosening the cuff: important new advances in modeling antihypertensive treatment effects in genetic studies of hypertension. Hypertension 2003 1.08
62 Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. Eur J Hum Genet 2002 1.07
63 SimHap GUI: an intuitive graphical user interface for genetic association analysis. BMC Bioinformatics 2008 1.06
64 Infants with flow limitation at 4 weeks: outcome at 6 and 11 years. Am J Respir Crit Care Med 2002 1.05
65 A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome. BMC Med Genet 2013 1.04
66 Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions. Respirology 2010 1.00
67 The apolipoprotein AII rs5082 variant is associated with reduced risk of coronary artery disease in an Australian male population. Atherosclerosis 2008 0.99
68 Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration. Ophthalmology 2009 0.99
69 High prevalence of undiagnosed obstructive sleep apnoea in the general population and methods for screening for representative controls. Sleep Breath 2012 0.96
70 Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One 2013 0.96
71 Covariance components models for longitudinal family data. Int J Epidemiol 2005 0.96
72 Single-nucleotide polymorphisms in the interleukin-10 gene: differences in frequencies, linkage disequilibrium patterns, and haplotypes in three United States ethnic groups. Genomics 2002 0.95
73 Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels. Am J Respir Crit Care Med 2003 0.93
74 Postdisaster emotional distress, depression and event-related variables: findings across child and adolescent developmental stages. Aust N Z J Psychiatry 2002 0.92
75 Association of an allele on chromosome 9 and abdominal aortic aneurysm. Atherosclerosis 2010 0.91
76 Association of an allelic variant of interleukin-6 with subclinical carotid atherosclerosis in an Australian community population. Eur Heart J 2003 0.90
77 Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease. Hum Genet 2007 0.90
78 Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease. Hepatology 2013 0.89
79 Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm. Atherosclerosis 2009 0.89
80 Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes. Am J Med Genet B Neuropsychiatr Genet 2008 0.89
81 Association of PPARgamma allelic variation, osteoprotegerin and abdominal aortic aneurysm. Clin Endocrinol (Oxf) 2009 0.87
82 Relationship between obstructive sleep apnea and diurnal leptin rhythms. Sleep 2004 0.87
83 Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters. J Clin Endocrinol Metab 2011 0.87
84 Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea. J Clin Sleep Med 2013 0.87
85 Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population data. PLoS One 2011 0.86
86 Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity. J Gastroenterol Hepatol 2012 0.85
87 Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS). Stroke 2003 0.85
88 Prenatal, perinatal, and heritable influences on cord blood immune responses. Ann Allergy Asthma Immunol 2006 0.85
89 Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude. Clin Neurophysiol 2011 0.85
90 Genetic influences on trajectories of systolic blood pressure across childhood and adolescence. Circ Cardiovasc Genet 2013 0.84
91 15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intima-media thickness. Hum Genet 2008 0.84
92 Modelling BMI trajectories in children for genetic association studies. PLoS One 2013 0.84
93 Make it HuGE: human genome epidemiology reviews, population health, and the IJE. Int J Epidemiol 2006 0.83
94 Nuclear factor kappa B activation in human cord blood mononuclear cells. Pediatr Res 2004 0.83
95 DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma. Am J Respir Crit Care Med 2002 0.83
96 Association of Interleukin-1 gene polymorphisms with central obesity and metabolic syndrome in a coronary heart disease population. Hum Genet 2008 0.83
97 Celestial3D: a novel method for 3D visualization of familial data. Bioinformatics 2008 0.82
98 Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus. J Diabetes Complications 2008 0.82
99 Rationale, design and methods for a community-based study of clustering and cumulative effects of chronic disease processes and their effects on ageing: the Busselton healthy ageing study. BMC Public Health 2013 0.81
100 Smoking status and occupational exposure affects oxidative DNA injury in boilermakers exposed to metal fume and residual oil fly ash. Cancer Epidemiol Biomarkers Prev 2004 0.81
101 1-hydroxypyrene as a biomarker of occupational exposure to polycyclic aromatic hydrocarbons (PAH) in boilermakers. J Occup Environ Med 2002 0.81
102 Association of PARL rs3732581 genetic variant with insulin levels, metabolic syndrome and coronary artery disease. Hum Genet 2008 0.81
103 The effect of missing data on linkage disequilibrium mapping and haplotype association analysis in the GAW14 simulated datasets. BMC Genet 2005 0.81
104 Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma. J Allergy Clin Immunol 2006 0.81
105 Urinary metal and polycyclic aromatic hydrocarbon biomarkers in boilermakers exposed to metal fume and residual oil fly ash. Am J Ind Med 2005 0.81
106 Investigating the association between K198N coding polymorphism in EDN1 and hypertension, lipoprotein levels, the metabolic syndrome and cardiovascular disease. Hum Genet 2008 0.81
107 A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. Am J Hypertens 2009 0.80
108 Stromelysin-1 (MMP-3) gene 5A/6A promoter polymorphism is associated with blood pressure in a community population. J Hypertens 2005 0.80
109 A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm. Eur J Hum Genet 2010 0.78
110 The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI. BMC Med Genet 2010 0.78
111 Effectiveness of individual-focused interventions to prevent chronic disease. Eur J Clin Invest 2014 0.77
112 A vision for chronic disease prevention intervention research: report from a workshop. Can J Public Health 2014 0.77
113 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Circ Cardiovasc Genet 2016 0.77
114 The role of prostaglandin D receptor gene in asthma pathogenesis. Am J Respir Cell Mol Biol 2005 0.77
115 A genome-wide association study for malignant mesothelioma risk. Lung Cancer 2013 0.77
116 Functional haplotypes in the PTGDR gene fail to associate with asthma in two Australian populations. Respirology 2011 0.76
117 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
118 Lack of reproducibility of linkage results in serially measured blood pressure data. BMC Genet 2003 0.75
119 Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts. PLoS One 2012 0.75
120 Correction: genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. PLoS One 2015 0.75
121 Response to Epstein et al. Am J Hum Genet 2002 0.75
122 Genome-wide linkage and association mapping of disease genes with the GAW14 simulated datasets. BMC Genet 2005 0.75
123 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
124 Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study. Prev Med 2012 0.75
125 Respiratory infections and lung function in an Australian Aboriginal community. Respirology 2008 0.75
126 The Western Australian Melanoma Health Study: study design and participant characteristics. Cancer Epidemiol 2011 0.75
127 The Western Australian Twin Register: a population-based register of adult and child multiples. Twin Res Hum Genet 2006 0.75
128 The New Epidemiology: putting the pieces together in complex disease aetiology. Int J Epidemiol 2004 0.75