Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
2
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
3
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
4
|
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|
Nat Genet
|
2012
|
5.48
|
5
|
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
|
Lancet
|
2012
|
3.48
|
6
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
7
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
8
|
Identification of genetic loci associated with Helicobacter pylori serologic status.
|
JAMA
|
2013
|
3.15
|
9
|
Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction.
|
JAMA
|
2004
|
2.93
|
10
|
The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis.
|
Ann Intern Med
|
2006
|
2.74
|
11
|
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.
|
Arthritis Rheum
|
2009
|
2.47
|
12
|
Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes.
|
JAMA
|
2004
|
2.20
|
13
|
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
|
Hum Mol Genet
|
2009
|
2.03
|
14
|
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.
|
Arthritis Rheum
|
2010
|
2.02
|
15
|
Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study.
|
Am J Hum Genet
|
2005
|
1.97
|
16
|
The association between lumbar disc degeneration and low back pain: the influence of age, gender, and individual radiographic features.
|
Spine (Phila Pa 1976)
|
2010
|
1.94
|
17
|
Mild hyponatremia as a risk factor for fractures: the Rotterdam Study.
|
J Bone Miner Res
|
2011
|
1.77
|
18
|
Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
|
Nat Genet
|
2009
|
1.72
|
19
|
Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study.
|
PLoS Med
|
2006
|
1.68
|
20
|
Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk.
|
Arthritis Rheum
|
2013
|
1.65
|
21
|
Methylenetetrahydrofolate reductase C677T genotype and PD.
|
Ann Neurol
|
2005
|
1.64
|
22
|
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis.
|
Hum Mol Genet
|
2008
|
1.60
|
23
|
A variant in MCF2L is associated with osteoarthritis.
|
Am J Hum Genet
|
2011
|
1.60
|
24
|
SIRT1 genetic variation is related to BMI and risk of obesity.
|
Diabetes
|
2009
|
1.44
|
25
|
Vitamin D receptor gene polymorphisms in relation to Vitamin D related disease states.
|
J Steroid Biochem Mol Biol
|
2004
|
1.36
|
26
|
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.
|
Proc Natl Acad Sci U S A
|
2012
|
1.28
|
27
|
Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites.
|
Am J Hum Genet
|
2004
|
1.26
|
28
|
High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study.
|
Diabetes Care
|
2013
|
1.19
|
29
|
Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly.
|
J Bone Miner Res
|
2003
|
1.18
|
30
|
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.
|
Ann Rheum Dis
|
2012
|
1.13
|
31
|
Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women.
|
J Bone Miner Res
|
2006
|
1.10
|
32
|
Vitamin D receptor gene haplotype is associated with body height and bone size.
|
J Clin Endocrinol Metab
|
2007
|
1.10
|
33
|
Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women.
|
Eur J Endocrinol
|
2005
|
1.09
|
34
|
Vitamin D binding protein genotype and osteoporosis.
|
Calcif Tissue Int
|
2009
|
1.07
|
35
|
Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.
|
Bone
|
2007
|
1.07
|
36
|
Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index.
|
Ann Rheum Dis
|
2010
|
1.05
|
37
|
Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 and folic acid on fracture incidence.
|
BMC Geriatr
|
2011
|
1.00
|
38
|
Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms.
|
J Clin Endocrinol Metab
|
2004
|
0.99
|
39
|
SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin.
|
Free Radic Biol Med
|
2009
|
0.97
|
40
|
Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: a meta-analysis.
|
Bone
|
2006
|
0.97
|
41
|
The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men.
|
J Clin Endocrinol Metab
|
2007
|
0.94
|
42
|
No clear association between female hormonal aspects and osteoarthritis of the hand, hip and knee: a systematic review.
|
Rheumatology (Oxford)
|
2009
|
0.93
|
43
|
Body mass index is an important determinant of methylation biomarkers in women of reproductive ages.
|
J Nutr
|
2009
|
0.90
|
44
|
Epigenetic Signatures of Cigarette Smoking.
|
Circ Cardiovasc Genet
|
2016
|
0.88
|
45
|
Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus.
|
Bone
|
2014
|
0.88
|
46
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
47
|
Genetic variation in homocysteine metabolism, cognition, and white matter lesions.
|
Neurobiol Aging
|
2008
|
0.88
|
48
|
Effect of dietary B vitamins on BMD and risk of fracture in elderly men and women: the Rotterdam study.
|
Bone
|
2007
|
0.87
|
49
|
The role of vitamin D receptor gene polymorphisms in bone biology.
|
Mol Cell Endocrinol
|
2002
|
0.85
|
50
|
The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study.
|
Calcif Tissue Int
|
2007
|
0.85
|
51
|
A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease.
|
Hum Mutat
|
2014
|
0.85
|
52
|
Factors for pain in patients with different grades of knee osteoarthritis.
|
Arthritis Care Res (Hoboken)
|
2013
|
0.84
|
53
|
A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.
|
J Med Genet
|
2013
|
0.84
|
54
|
Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index.
|
Am J Clin Nutr
|
2010
|
0.84
|
55
|
Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners.
|
J Appl Physiol (1985)
|
2009
|
0.81
|
56
|
Vitamin D-binding protein polymorphisms are not associated with development of (multiple) basal cell carcinomas.
|
Exp Dermatol
|
2010
|
0.81
|
57
|
Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study.
|
Drugs Aging
|
2014
|
0.80
|
58
|
Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis.
|
BMC Med Genet
|
2010
|
0.79
|
59
|
Scheuermann disease: evaluation of radiological criteria and population prevalence.
|
Spine (Phila Pa 1976)
|
2013
|
0.79
|
60
|
Scheuermann's Disease: Evaluation of Radiological Criteria and Population Prevalence.
|
Spine (Phila Pa 1976)
|
2013
|
0.78
|
61
|
Homocysteine and fracture prevention.
|
JAMA
|
2005
|
0.78
|
62
|
The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study.
|
Bone
|
2007
|
0.77
|
63
|
Finger length pattern as a biomarker for osteoarthritis and chronic joint pain: a population-based study and meta-analysis after systematic review.
|
Arthritis Care Res (Hoboken)
|
2014
|
0.76
|
64
|
Genetic polymorphisms in the locus control region and promoter of GH1 are related to serum IGF-I levels and height in patients with isolated growth hormone deficiency and healthy controls.
|
Horm Res Paediatr
|
2010
|
0.75
|
65
|
A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone.
|
Thyroid
|
2012
|
0.75
|
66
|
Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women.
|
Pain
|
2016
|
0.75
|