Published in BMC Genomics on November 24, 2010
Control of virulence by small RNAs in Streptococcus pneumoniae. PLoS Pathog (2012) 1.46
Identification of 88 regulatory small RNAs in the TIGR4 strain of the human pathogen Streptococcus pneumoniae. RNA (2012) 0.99
An in silico model for identification of small RNAs in whole bacterial genomes: characterization of antisense RNAs in pathogenic Escherichia coli and Streptococcus agalactiae strains. Nucleic Acids Res (2011) 0.97
Small regulatory RNAs from low-GC Gram-positive bacteria. RNA Biol (2014) 0.91
Single nucleotide resolution RNA-seq uncovers new regulatory mechanisms in the opportunistic pathogen Streptococcus agalactiae. BMC Genomics (2015) 0.87
Sibling rivalry: related bacterial small RNAs and their redundant and non-redundant roles. Front Cell Infect Microbiol (2014) 0.84
Small regulatory RNAs in Streptococcus pneumoniae: discovery and biological functions. Front Genet (2015) 0.80
Highly Variable Streptococcus oralis Strains Are Common among Viridans Streptococci Isolated from Primates. mSphere (2016) 0.79
Regulatory RNAs in the Less Studied Streptococcal Species: From Nomenclature to Identification. Front Microbiol (2016) 0.79
Genome-wide analyses of small non-coding RNAs in streptococci. Front Genet (2015) 0.78
ManLMN is a glucose transporter and central metabolic regulator in Streptococcus pneumoniae. Mol Microbiol (2016) 0.77
Mutation of the Thiol-Disulfide Oxidoreductase SdbA Activates the CiaRH Two-Component System, Leading to Bacteriocin Expression Shutdown in Streptococcus gordonii. J Bacteriol (2015) 0.76
RNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenes. RNA Biol (2016) 0.76
Two novel members of the LhrC family of small RNAs in Listeria monocytogenes with overlapping regulatory functions but distinctive expression profiles. RNA Biol (2016) 0.76
Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. Cell Host Microbe (2016) 0.75
The Mechanisms of Virulence Regulation by Small Noncoding RNAs in Low GC Gram-Positive Pathogens. Int J Mol Sci (2015) 0.75
Identification, Functional Characterization and Regulon Prediction of a Novel Two Component System Comprising BAS0540-BAS0541 of Bacillus anthracis. PLoS One (2016) 0.75
New aspects of the interplay between penicillin binding proteins, murM and the two component system CiaRH of penicillin-resistant Streptococcus pneumoniae serotype 19A isolates from Hungary. Antimicrob Agents Chemother (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc Natl Acad Sci U S A (1974) 62.91
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
Regulatory RNAs in bacteria. Cell (2009) 9.57
The Listeria transcriptional landscape from saprophytism to virulence. Nature (2009) 5.88
Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus. Nat Biotechnol (2004) 5.40
The bacterial Sm-like protein Hfq: a key player in RNA transactions. Mol Microbiol (2004) 4.88
Release of genetic transforming agent from pneumococcal cultures during growth and disintegration. J Exp Med (1962) 4.45
Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptake. Genome Biol (2007) 4.27
Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets. Nucleic Acids Res (2007) 2.75
Structural relationships in the OmpR family of winged-helix transcription factors. J Mol Biol (1997) 2.73
The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor. Structure (1997) 2.63
Small RNA genes expressed from Staphylococcus aureus genomic and pathogenicity islands with specific expression among pathogenic strains. Proc Natl Acad Sci U S A (2005) 2.55
The role of Hfq in bacterial pathogens. Curr Opin Microbiol (2010) 2.40
Cell envelope stress response in Gram-positive bacteria. FEMS Microbiol Rev (2008) 2.32
Appearance of genetic transforming activity in pneumococcal cultures. Science (1960) 2.26
Experimental discovery of sRNAs in Vibrio cholerae by direct cloning, 5S/tRNA depletion and parallel sequencing. Nucleic Acids Res (2009) 2.25
Group A streptococcal growth phase-associated virulence factor regulation by a novel operon (Fas) with homologies to two-component-type regulators requires a small RNA molecule. Mol Microbiol (2001) 2.24
A two-component signal-transducing system is involved in competence and penicillin susceptibility in laboratory mutants of Streptococcus pneumoniae. Mol Microbiol (1994) 2.22
Genome of the opportunistic pathogen Streptococcus sanguinis. J Bacteriol (2007) 2.21
Interconnection of competence, stress and CiaR regulons in Streptococcus pneumoniae: competence triggers stationary phase autolysis of ciaR mutant cells. Mol Microbiol (2004) 2.10
The transcriptionally active regions in the genome of Bacillus subtilis. Mol Microbiol (2009) 2.02
Identification of small RNAs in diverse bacterial species. Curr Opin Microbiol (2007) 2.01
The Streptococcus pneumoniae cia regulon: CiaR target sites and transcription profile analysis. J Bacteriol (2003) 1.99
Identification of regulatory RNAs in Bacillus subtilis. Nucleic Acids Res (2010) 1.99
Identification of bacterial small non-coding RNAs: experimental approaches. Curr Opin Microbiol (2007) 1.98
Experimental approaches for the discovery and characterization of regulatory small RNA. Curr Opin Microbiol (2009) 1.92
Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule. Mol Microbiol (2004) 1.92
Role of HtrA in growth and competence of Streptococcus mutans UA159. J Bacteriol (2005) 1.86
No detectable effect of RNA-binding protein Hfq absence in Staphylococcus aureus. BMC Microbiol (2007) 1.79
A functional dlt operon, encoding proteins required for incorporation of d-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae. J Bacteriol (2006) 1.69
Inactivation of the ciaH Gene in Streptococcus mutans diminishes mutacin production and competence development, alters sucrose-dependent biofilm formation, and reduces stress tolerance. Infect Immun (2004) 1.62
The genome of Streptococcus mitis B6--what is a commensal? PLoS One (2010) 1.51
Identification of the genes directly controlled by the response regulator CiaR in Streptococcus pneumoniae: five out of 15 promoters drive expression of small non-coding RNAs. Mol Microbiol (2007) 1.50
Involvement of sensor kinases in the stress tolerance response of Streptococcus mutans. J Bacteriol (2007) 1.50
Genetic loci of Streptococcus mitis that mediate binding to human platelets. Infect Immun (2001) 1.38
A new integrative reporter plasmid for Streptococcus pneumoniae. FEMS Microbiol Lett (2007) 1.37
A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus. PLoS One (2009) 1.36
A global gene pool for high-level cephalosporin resistance in commensal Streptococcus species and Streptococcus pneumoniae. J Infect Dis (1997) 1.33
Defining a role for Hfq in Gram-positive bacteria: evidence for Hfq-dependent antisense regulation in Listeria monocytogenes. Nucleic Acids Res (2009) 1.25
Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae. J Bacteriol (2004) 1.23
Systemic inactivation and phenotypic characterization of two-component systems in expression of Streptococcus mutans virulence properties. Lett Appl Microbiol (2007) 1.23
On the facultative requirement of the bacterial RNA chaperone, Hfq. Trends Microbiol (2009) 1.21
Identification and characterization of noncoding small RNAs in Streptococcus pneumoniae serotype 2 strain D39. J Bacteriol (2010) 1.19
The CiaRH system of Streptococcus pneumoniae prevents lysis during stress induced by treatment with cell wall inhibitors and by mutations in pbp2x involved in beta-lactam resistance. J Bacteriol (2006) 1.16
RivR and the small RNA RivX: the missing links between the CovR regulatory cascade and the Mga regulon. Mol Microbiol (2007) 1.16
Pneumococcal HtrA protease mediates inhibition of competence by the CiaRH two-component signaling system. J Bacteriol (2005) 1.15
Identification of novel non-coding small RNAs from Streptococcus pneumoniae TIGR4 using high-resolution genome tiling arrays. BMC Genomics (2010) 1.12
The CiaR response regulator in group B Streptococcus promotes intracellular survival and resistance to innate immune defenses. J Bacteriol (2008) 1.08
Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation. J Bacteriol (2008) 1.02
Multiple two-component systems modulate alkali generation in Streptococcus gordonii in response to environmental stresses. J Bacteriol (2009) 1.01
Sequence analysis and characterization of plasmids from Streptococcus thermophilus. Plasmid (2003) 0.89
Multiple two-component systems of Streptococcus mutans regulate agmatine deiminase gene expression and stress tolerance. J Bacteriol (2009) 0.89
Small RNAs shed some light. Cell (2004) 0.86
Regulation of ciaXRH operon expression and identification of the CiaR regulon in Streptococcus mutans. J Bacteriol (2010) 0.85
Transcriptome analyses extend understanding of Streptococcus pyogenes regulatory mechanisms and behavior toward immunomodulatory substances. Int J Med Microbiol (2007) 0.83
Ensembl Genomes 2013: scaling up access to genome-wide data. Nucleic Acids Res (2013) 3.08
Ensembl Genomes: an integrative resource for genome-scale data from non-vertebrate species. Nucleic Acids Res (2011) 2.87
Anthrax kills wild chimpanzees in a tropical rainforest. Nature (2004) 2.01
The Streptococcus pneumoniae cia regulon: CiaR target sites and transcription profile analysis. J Bacteriol (2003) 1.99
A functional dlt operon, encoding proteins required for incorporation of d-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae. J Bacteriol (2006) 1.69
The genome of Streptococcus mitis B6--what is a commensal? PLoS One (2010) 1.51
Identification of the genes directly controlled by the response regulator CiaR in Streptococcus pneumoniae: five out of 15 promoters drive expression of small non-coding RNAs. Mol Microbiol (2007) 1.50
Pneumococcal capsular switching: a historical perspective. J Infect Dis (2012) 1.43
Diversity of bacteriocins and activity spectrum in Streptococcus pneumoniae. J Bacteriol (2007) 1.38
Crossing the barrier: evolution and spread of a major class of mosaic pbp2x in Streptococcus pneumoniae, S. mitis and S. oralis. Int J Med Microbiol (2007) 1.38
A new integrative reporter plasmid for Streptococcus pneumoniae. FEMS Microbiol Lett (2007) 1.37
Mosaic genes and mosaic chromosomes-genomic variation in Streptococcus pneumoniae. Int J Med Microbiol (2004) 1.20
Molecular mechanisms of β-lactam resistance in Streptococcus pneumoniae. Future Microbiol (2012) 1.20
The CiaRH system of Streptococcus pneumoniae prevents lysis during stress induced by treatment with cell wall inhibitors and by mutations in pbp2x involved in beta-lactam resistance. J Bacteriol (2006) 1.16
The two-component regulatory system TCS08 is involved in cellobiose metabolism of Streptococcus pneumoniae R6. J Bacteriol (2006) 1.16
The pneumococcal cell envelope stress-sensing system LiaFSR is activated by murein hydrolases and lipid II-interacting antibiotics. J Bacteriol (2010) 1.12
Genome of Streptococcus oralis strain Uo5. J Bacteriol (2011) 1.08
The ciaR/ciaH regulatory network of Streptococcus pneumoniae. J Mol Microbiol Biotechnol (2002) 1.07
Biosynthesis of teichoic acids in Streptococcus pneumoniae and closely related species: lessons from genomes. Microb Drug Resist (2012) 1.05
Versatility of choline metabolism and choline-binding proteins in Streptococcus pneumoniae and commensal streptococci. FEMS Microbiol Rev (2009) 1.03
Ins and outs of glucose transport systems in eubacteria. FEMS Microbiol Rev (2008) 1.02
Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974. BMC Genomics (2013) 1.01
The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success. Genome Biol (2012) 1.01
New Streptococcus pneumoniae clones in deceased wild chimpanzees. J Bacteriol (2007) 0.99
An important site in PBP2x of penicillin-resistant clinical isolates of Streptococcus pneumoniae: mutational analysis of Thr338. Antimicrob Agents Chemother (2008) 0.97
Streptococcus pneumoniae R6 interspecies transformation: genetic analysis of penicillin resistance determinants and genome-wide recombination events. Mol Microbiol (2012) 0.96
An ABC transporter of Streptococcus pneumoniae involved in susceptibility to vancoresmycin and bacitracin. Antimicrob Agents Chemother (2009) 0.94
Target evaluation of the non-coding csRNAs reveals a link of the two-component regulatory system CiaRH to competence control in Streptococcus pneumoniae R6. Mol Microbiol (2013) 0.92
Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for cell shape maintenance. Mol Microbiol (2014) 0.91
Carbon catabolite repression by the catabolite control protein CcpA in Staphylococcus xylosus. J Mol Microbiol Biotechnol (2002) 0.90
Characterisation of the katA gene encoding a catalase and evidence for at least a second catalase activity in Staphylococcus xylosus, bacteria used in food fermentation. FEMS Microbiol Lett (2002) 0.90
Highly variable penicillin resistance determinants PBP 2x, PBP 2b, and PBP 1a in isolates of two Streptococcus pneumoniae clonal groups, Poland 23F-16 and Poland 6B-20. Antimicrob Agents Chemother (2007) 0.90
Activity of the two-component regulatory system CiaRH in Streptococcus pneumoniae R6. J Mol Microbiol Biotechnol (2011) 0.89
Mutations in Streptococcus pneumoniae penicillin-binding protein 2x: importance of the C-terminal penicillin-binding protein and serine/threonine kinase-associated domains for beta-lactam binding. Microb Drug Resist (2012) 0.88
Penicillin-binding protein 2x of Streptococcus pneumoniae: three new mutational pathways for remodelling an essential enzyme into a resistance determinant. J Mol Biol (2008) 0.87
Carbon catabolite repression of sucrose utilization in Staphylococcus xylosus: catabolite control protein CcpA ensures glucose preference and autoregulatory limitation of sucrose utilization. J Mol Microbiol Biotechnol (2007) 0.85
Different pathways of choline metabolism in two choline-independent strains of Streptococcus pneumoniae and their impact on virulence. J Bacteriol (2008) 0.85
Effect of new alleles of the histidine kinase gene ciaH on the activity of the response regulator CiaR in Streptococcus pneumoniae R6. Microbiology (2011) 0.83
Characterization of German penicillin non-susceptible serotype 23F pneumococci using multilocus sequence typing. J Med Microbiol (2003) 0.83
Penicillin-binding protein 2x of Streptococcus pneumoniae: the mutation Ala707Asp within the C-terminal PASTA2 domain leads to destabilization. Microb Drug Resist (2014) 0.80
Williopsis saturnus yeast killer toxin does not kill Streptococcus pneumoniae. Antonie Van Leeuwenhoek (2010) 0.78
A XerD recombinase with unusual active site motifs in Streptococcus pneumoniae. J Mol Microbiol Biotechnol (2002) 0.78
The capsule of Streptococcus pneumoniae contributes to virulence in the insect model Manduca sexta. J Mol Microbiol Biotechnol (2012) 0.77
A new variant of the capsule 3 cluster occurs in Streptococcus pneumoniae from deceased wild chimpanzees. PLoS One (2011) 0.76
A tetracycline inducible integrative expression system for Streptococcus pneumoniae. FEMS Microbiol Lett (2017) 0.75