Assessing the potential for AAV vector genotoxicity in a murine model.

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Published in Blood on November 24, 2010

Authors

Hojun Li1, Nirav Malani, Shari R Hamilton, Alexander Schlachterman, Giulio Bussadori, Shyrie E Edmonson, Rachel Shah, Valder R Arruda, Federico Mingozzi, J Fraser Wright, Frederic D Bushman, Katherine A High

Author Affiliations

1: Department of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Associated clinical trials:

Dose-Escalation Study Of A Self Complementary Adeno-Associated Viral Vector For Gene Transfer in Hemophilia B | NCT00979238

LTFU for Gene Transfer Subjects With Hemophilia B | NCT00515710

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