Published in Behav Brain Res on November 27, 2010
The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building? Neuropharmacology (2011) 1.36
The melatonergic system in mood and anxiety disorders and the role of agomelatine: implications for clinical practice. Int J Mol Sci (2013) 0.92
Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats. Psychopharmacology (Berl) (2011) 0.90
Neuroplasticity and major depression, the role of modern antidepressant drugs. World J Psychiatry (2012) 0.87
Testosterone and imipramine have antidepressant effects in socially isolated male but not female rats. Horm Behav (2012) 0.84
Anger Emotional Stress Influences VEGF/VEGFR2 and Its Induced PI3K/AKT/mTOR Signaling Pathway. Neural Plast (2016) 0.81
Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties. Br J Pharmacol (2014) 0.80
The maternal brain: an organ with peripartal plasticity. Neural Plast (2014) 0.80
Neuroimmunomodulation in unipolar depression: a focus on chronobiology and chronotherapeutics. J Neural Transm (Vienna) (2012) 0.78
Effect of sertraline on proliferation and neurogenic differentiation of human adipose-derived stem cells. Adv Biomed Res (2014) 0.76
Analytical strategies for the marble burying test: avoiding impossible predictions and invalid p-values. BMC Res Notes (2015) 0.75
Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing 5-HT3AR and 5-HT3BR Expression in the Rat Brain. Neural Plast (2016) 0.75
The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease. Neurosci Biobehav Rev (2004) 3.10
Coping styles and behavioural flexibility: towards underlying mechanisms. Philos Trans R Soc Lond B Biol Sci (2010) 2.02
Defensive burying in rodents: ethology, neurobiology and psychopharmacology. Eur J Pharmacol (2003) 1.61
Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol Psychiatry (2006) 1.53
Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat. Behav Brain Res (2007) 1.48
Agomelatine, the first melatonergic antidepressant: discovery, characterization and development. Nat Rev Drug Discov (2010) 1.47
A new animal welfare concept based on allostasis. Physiol Behav (2006) 1.47
Long-term effects of social stress on brain and behavior: a focus on hippocampal functioning. Neurosci Biobehav Rev (2004) 1.44
Evaluation of the effects of therapeutic and supratherapeutic doses of agomelatine on the QT/QTc interval: a phase I, randomized, double-blind, placebo-controlled and positive-controlled, crossover thorough QT/QTc study conducted in healthy volunteers. J Cardiovasc Pharmacol (2014) 1.39
Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies. Eur J Pharmacol (2005) 1.34
Enhancement of attentional performance by selective stimulation of alpha4beta2(*) nAChRs: underlying cholinergic mechanisms. Neuropsychopharmacology (2010) 1.31
5-HT1A and 5-HT1B receptor agonists and aggression: a pharmacological challenge of the serotonin deficiency hypothesis. Eur J Pharmacol (2005) 1.28
Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice. J Biol Chem (2003) 1.17
Individual variation in aggression of feral rodent strains: a standard for the genetics of aggression and violence? Behav Genet (2003) 1.17
Poor sleep as a potential causal factor in aggression and violence. Sleep Med (2012) 1.10
Methotrexate decreases hippocampal cell proliferation and induces memory deficits in rats. Behav Brain Res (2009) 1.08
Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression. Horm Behav (2003) 1.06
Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription. Biochem J (2004) 1.04
Social behavior and social stress in adolescence: a focus on animal models. Neurosci Biobehav Rev (2010) 1.03
Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus. Neuropsychopharmacology (2009) 1.01
Effect of agomelatine in the chronic mild stress model of depression in the rat. Neuropsychopharmacology (2002) 1.01
Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. Int J Neuropsychopharmacol (2009) 1.01
Differential role of the 5-HT1A receptor in aggressive and non-aggressive mice: an across-strain comparison. Physiol Behav (2007) 0.99
A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day. Sleep (2010) 0.99
Development of violence in mice through repeated victory along with changes in prefrontal cortex neurochemistry. Behav Brain Res (2008) 0.99
Social stress during adolescence in Wistar rats induces social anxiety in adulthood without affecting brain monoaminergic content and activity. Physiol Behav (2007) 0.99
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology (2009) 0.98
Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. J Biol Chem (2005) 0.98
The vicious cycle towards violence: focus on the negative feedback mechanisms of brain serotonin neurotransmission. Front Behav Neurosci (2009) 0.98
Activation of serotonergic neurotransmission during the performance of aggressive behavior in rats. Behav Neurosci (2003) 0.95
S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo. J Pharmacol Exp Ther (2007) 0.94
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis. Mol Cell Neurosci (2002) 0.93
Methotrexate reduces hippocampal blood vessel density and activates microglia in rats but does not elevate central cytokine release. Behav Brain Res (2009) 0.93
The acute glucocorticoid stress response does not differentiate between rewarding and aversive social stimuli in rats. Horm Behav (2011) 0.92
Social Defeat during Adolescence and Adulthood Differentially Induce BDNF-Regulated Immediate Early Genes. Front Behav Neurosci (2011) 0.92
Social environment determines the long-term effects of social defeat. Physiol Behav (2004) 0.91
Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors. J Psychiatry Neurosci (2004) 0.91
Basal and stress-induced differences in HPA axis, 5-HT responsiveness, and hippocampal cell proliferation in two mouse lines. Ann N Y Acad Sci (2004) 0.90
Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats. Psychopharmacology (Berl) (2011) 0.90
The cholinergic system and depression. Behav Brain Res (2010) 0.90
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.89
Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model. Behav Pharmacol (2006) 0.89
Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration. World J Biol Psychiatry (2010) 0.88
Testosterone decrease does not play a major role in the suppression of hippocampal cell proliferation following social defeat stress in rats. Physiol Behav (2010) 0.87
Antiaggressive activity of central oxytocin in male rats. Psychopharmacology (Berl) (2013) 0.87
An animal model of emotional blunting in schizophrenia. PLoS One (2007) 0.87
A single social defeat induces short-lasting behavioral sensitization to amphetamine. Physiol Behav (2004) 0.87
The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats. Int J Neuropsychopharmacol (2008) 0.87
Anxiolytic-like action of the antidepressant agomelatine (S 20098) after a social defeat requires the integrity of the SCN. Eur Neuropsychopharmacol (2005) 0.87
Sleep deprivation impairs contextual fear conditioning and attenuates subsequent behavioural, endocrine and neuronal responses. J Sleep Res (2010) 0.86
Toward an animal model for antisocial behavior: parallels between mice and humans. Behav Genet (2003) 0.86
Differences in the effects of 5-HT(1A) receptor agonists on forced swimming behavior and brain 5-HT metabolism between low and high aggressive mice. Psychopharmacology (Berl) (2004) 0.86
Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat. Pharmacol Biochem Behav (2011) 0.86
Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor. Brain Res Bull (2009) 0.86
Adrenocortical reactivity and central serotonin and dopamine turnover in young chicks from a high and low feather-pecking line of laying hens. Physiol Behav (2002) 0.86
Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Behav Pharmacol (2006) 0.86
Delineation of violence from functional aggression in mice: an ethological approach. Behav Genet (2008) 0.85
The stress response to sensory contact in mice: genotype effect of the stimulus animal. Psychoneuroendocrinology (2005) 0.85
Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC. Psychopharmacology (Berl) (2011) 0.85
Aggressive and non-aggressive personalities differ in oxidative status in selected lines of mice (Mus musculus). Biol Lett (2008) 0.84
Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology (2004) 0.84
Structural and electrical myocardial remodeling in a rodent model of depression. Psychosom Med (2012) 0.83
Differential long-term effects of social stress during adolescence on anxiety in Wistar and wild-type rats. Behav Processes (2011) 0.83
Chicks from a high and low feather pecking line of laying hens differ in apomorphine sensitivity. Physiol Behav (2005) 0.83
Cerebrospinal fluid monoamine and metabolite concentrations and aggression in rats. Horm Behav (2003) 0.83
Effect of increased serotonin levels on [18F]MPPF binding in rat brain: fenfluramine vs the combination of citalopram and ketanserin. Neuropsychopharmacology (2005) 0.82
Low tryptophan diet increases stress-sensitivity, but does not affect habituation in rats. Neurochem Int (2007) 0.82
Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine. Psychopharmacology (Berl) (2010) 0.82
Violent phenotype in SAL mice is inflexible and fixed in adulthood. Aggress Behav (2009) 0.82
The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders. J Neurosci (2014) 0.82
The antidepressant agomelatine inhibits stress-mediated changes in amino acid efflux in the rat hippocampus and amygdala. Brain Res (2012) 0.82
Social stress in male mice impairs long-term antiviral immunity selectively in wounded subjects. Physiol Behav (2002) 0.81
The control of feather pecking by serotonin. Behav Neurosci (2004) 0.81
Chronic agomelatine treatment corrects the abnormalities in the circadian rhythm of motor activity and sleep/wake cycle induced by prenatal restraint stress in adult rats. Int J Neuropsychopharmacol (2012) 0.81
Ketamine administration disturbs behavioural and distributed neural correlates of fear conditioning in the rat. Prog Neuropsychopharmacol Biol Psychiatry (2006) 0.80
Chronic agomelatine and fluoxetine induce antidepressant-like effects in H/Rouen mice, a genetic mouse model of depression. Pharmacol Biochem Behav (2011) 0.80
Chronic stress and antidepressant agomelatine induce region-specific changes in synapsin I expression in the rat brain. J Neurosci Res (2011) 0.80
Agomelatine suppresses locomotor hyperactivity in olfactory bulbectomised rats: a comparison to melatonin and to the 5-HT(2c) antagonist, S32006. Eur J Pharmacol (2011) 0.79
Male Wistar rats are more susceptible to lasting social anxiety than Wild-type Groningen rats following social defeat stress during adolescence. Behav Processes (2011) 0.79
Gender differences in hyperthermia and regional 5-HT and 5-HIAA depletion in the brain following MDMA administration in rats. Brain Res (2011) 0.79
Impulsivity and aggressive behavior in Roman high and low avoidance rats: baseline differences and adolescent social stress induced changes. Physiol Behav (2011) 0.79
Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes. BMC Neurosci (2013) 0.78
Abrupt rather than gradual hormonal changes induce postpartum blues-like behavior in rats. Life Sci (2008) 0.78
Does the early social environment affect structure and consistency of personality in wild-type male's rat? Dev Psychobiol (2011) 0.78
Neonatal handling increases sensitivity to acute neurodegeneration in adult rats. J Neurobiol (2004) 0.78
The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats. CNS Neurosci Ther (2010) 0.78
Like melatonin, agomelatine (S20098) increases the amplitude of oscillations of two clock outputs: melatonin and temperature rhythms. Chronobiol Int (2013) 0.78