High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 3072510)

Published in Leukemia on November 30, 2010

Authors

R Quéré1, S Andradottir, A C M Brun, R A Zubarev, G Karlsson, K Olsson, M Magnusson, J Cammenga, S Karlsson

Author Affiliations

1: Molecular Medicine and Gene Therapy, Division of Molecular Medicine and Gene Therapy, Lund Strategic Center for Stem Cell Biology and Cell Therapy, Lund University Hospital, Lund, Sweden.

Articles cited by this

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science (1999) 83.27

Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med (2006) 5.92

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J (1998) 5.21

How do stem cells find their way home? Blood (2005) 5.13

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene (2001) 4.70

HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood (2008) 3.12

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9. Nat Genet (1996) 3.05

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci U S A (2001) 2.84

Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia. Mol Cell Biol (2001) 2.80

Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet (1996) 2.78

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat Med (2006) 2.69

Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol (1997) 2.61

AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol (1997) 2.56

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis. Blood (2004) 2.11

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Mol Cell Biol (1999) 2.06

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci U S A (2005) 2.03

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. Blood (2000) 1.91

Coordinate regulation of HOX genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1991) 1.88

The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells (1996) 1.86

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. Leukemia (1999) 1.80

NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J (2001) 1.78

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. Proc Natl Acad Sci U S A (2003) 1.69

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice. J Clin Invest (2005) 1.68

Regulatable gene expression systems for gene therapy applications: progress and future challenges. Mol Ther (2005) 1.61

Matrix metalloproteinases: old dogs with new tricks. Genome Biol (2003) 1.59

Improving protein identification using complementary fragmentation techniques in fourier transform mass spectrometry. Mol Cell Proteomics (2005) 1.52

Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol (2004) 1.43

Retroviral insertion mutagenesis in mice as a comparative oncogenomics tool to identify disease genes in human leukemia. Mol Ther (2007) 1.39

Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain. Cancer Cell (2010) 1.39

Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood (2001) 1.34

Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression. Blood (2006) 1.31

Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia. Oncogene (2004) 1.26

HOX expression patterns identify a common signature for favorable AML. Leukemia (2008) 1.24

Effects of HOX homeobox genes in blood cell differentiation. J Cell Physiol (1997) 1.24

Commonly dysregulated genes in murine APL cells. Blood (2006) 1.18

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia. Blood (2006) 1.14

The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells. Mol Cell Biol (1999) 1.14

A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene. Blood (2008) 1.12

Second hit mutations in the RTK/RAS signaling pathway in acute myeloid leukemia with inv(16). Haematologica (2004) 1.10

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development. Blood (2007) 1.02

Proliferation of primitive myeloid progenitors can be reversibly induced by HOXA10. Blood (2001) 0.99

A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia. Blood (1998) 0.97

Significance of murine retroviral mutagenesis for identification of disease genes in human acute myeloid leukemia. Cancer Res (2006) 0.94

Expression of CD44 variant exons in acute myeloid leukemia is more common and more complex than that observed in normal blood, bone marrow or CD34+ cells. Leukemia (2000) 0.92

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities. Blood (2008) 0.87

Cooperation of activating Ras/rtk signal transduction pathway mutations and inactivating myeloid differentiation gene mutations in M0 AML: a study of 45 patients. Leukemia (2006) 0.84

AML1-ETO meets JAK2: clinical evidence for the two hit model of leukemogenesis from a myeloproliferative syndrome progressing to acute myeloid leukemia. Leukemia (2007) 0.79

Articles by these authors

(truncated to the top 100)

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A (1993) 10.82

Automated reduction and interpretation of high resolution electrospray mass spectra of large molecules. J Am Soc Mass Spectrom (2000) 5.44

Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization. J Virol (1996) 4.12

Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development (1995) 4.05

The antigens of Mycobacterium bovis, strain BCG, studied by crossed immunoelectrophoresis: a reference system. Scand J Immunol (1980) 3.50

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice. EMBO J (2001) 3.24

Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles. Proc Natl Acad Sci U S A (1996) 3.07

Mycolic acid patterns of some species of Mycobacterium. Arch Microbiol (1984) 3.02

Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J Exp Med (1997) 2.75

Localization of O-glycosylation sites in peptides by electron capture dissociation in a Fourier transform mass spectrometer. Anal Chem (1999) 2.48

Localization of labile posttranslational modifications by electron capture dissociation: the case of gamma-carboxyglutamic acid. Anal Chem (1999) 2.43

Developmental regulation of human globin genes. Annu Rev Biochem (1985) 2.16

Immune dysregulation in TGF-beta 1-deficient mice. J Immunol (1994) 2.00

Complexes between cationic liposomes and DNA visualized by cryo-TEM. Biochim Biophys Acta (1995) 1.89

Automated de novo sequencing of proteins by tandem high-resolution mass spectrometry. Proc Natl Acad Sci U S A (2000) 1.88

Effect of chronic renal failure on bone turnover and bone alkaline phosphatase isoforms. Kidney Int (2001) 1.88

Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. Proc Natl Acad Sci U S A (1989) 1.84

Dominant paternal transmission of Cornelia de Lange syndrome: a new case and review of 25 previously reported familial recurrences. Am J Med Genet (2001) 1.78

Outcome measurement in economic evaluation. Health Econ (1997) 1.69

Electron capture dissociation of singly and multiply phosphorylated peptides. Rapid Commun Mass Spectrom (2000) 1.65

Phase II study of oral fingolimod (FTY720) in multiple sclerosis: 3-year results. Mult Scler (2009) 1.65

Preoperative levosimendan infusion in combined aortic valve and coronary bypass surgery. Br J Anaesth (2011) 1.65

A co-operative numerical analysis of nonscoto- and nonphotochromogenic slowly growing mycobacteria. J Gen Microbiol (1974) 1.64

Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype. Proc Natl Acad Sci U S A (1993) 1.64

Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease. Am J Pathol (1993) 1.64

Serotonine and temperature control. Acta Physiol Scand (1966) 1.64

Three cases of neonatal meningitis caused by Enterobacter sakazakii in powdered milk. J Clin Microbiol (1989) 1.60

Identification of human postural dynamics. IEEE Trans Biomed Eng (1988) 1.59

Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance. J Am Soc Mass Spectrom (2001) 1.57

Aromatic DNA adducts in foundry workers in relation to exposure, life style and CYP1A1 and glutathione transferase M1 genotype. Carcinogenesis (1997) 1.53

Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse. Blood (1996) 1.51

A study of Mycobacterium fortuitum (ranae). J Med Microbiol (1974) 1.51

Arterial anatomy of the upper extremity. Acta Radiol Diagn (Stockh) (1982) 1.50

Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist. Stroke (2000) 1.47

Promoter sequences required for function of the human gamma globin gene in erythroid cells. EMBO J (1986) 1.47

Applications of electron-ion dissociation reactions for analysis of polycationic chitooligosaccharides in Fourier transform mass spectrometry. Anal Chem (2003) 1.47

Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity. Am J Obstet Gynecol (1983) 1.46

Treatment of Alzheimer disease with tacrine: a cost-analysis model. Alzheimer Dis Assoc Disord (1997) 1.42

Impact of implant interdependency when evaluating success rates: a statistical analysis of multicenter results. Int J Prosthodont (1999) 1.42

Whole-body vibration exposure and occupational work-hardening. J Occup Environ Med (1997) 1.41

CGP 35348: a centrally active blocker of GABAB receptors. Eur J Pharmacol (1990) 1.40

Improved low-energy electron injection systems for high rate electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom (2001) 1.40

Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci U S A (1993) 1.40

Two unusual pediatric presentations of sarcoidosis. Arch Pediatr Adolesc Med (1998) 1.40

[Flucticasone propionate is safe in recommended doses]. Lakartidningen (1997) 1.39

Parathyroid hormone-related protein in neonatal and reproductive goats determined by a sensitive time-resolved immunofluorometric assay. Eur J Endocrinol (1997) 1.39

Techview: biochemistry. Biomolecule mass spectrometry. Science (1999) 1.39

Carriage of respiratory tract pathogens and molecular epidemiology of Streptococcus pneumoniae colonization in healthy children attending day care centers in Lisbon, Portugal. Microb Drug Resist (1999) 1.38

Delineation of Nocardia farcinica by delayed type skin reactions on guinea pigs. J Gen Microbiol (1968) 1.38

Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. J Virol (2000) 1.38

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma. Genes Dev (1994) 1.37

Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry. Anal Chem (2001) 1.37

Water sorption and solubility of dental composites and identification of monomers released in an aqueous environment. J Oral Rehabil (2001) 1.37

Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein. Proc Natl Acad Sci U S A (1987) 1.34

Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest (1987) 1.33

The clinical condition of IgA-deficient patients is related to the proportion of IgD- and IgM-producing cells in their nasal mucosa. Clin Exp Immunol (1987) 1.29

Evaluation of three commercial enzyme-linked immunosorbent assays and two latex agglutination assays for diagnosis of primary Epstein-Barr virus infection. J Clin Microbiol (1997) 1.28

The prognostic impact of follow-up assessments in patients with idiopathic pulmonary arterial hypertension. Eur Respir J (2011) 1.28

Human postural dynamics. Crit Rev Biomed Eng (1991) 1.28

Characterization of purified protein derivative of tuberculin by use of monoclonal antibodies: isolation of a delayed-type hypersensitivity reactive component from M. tuberculosis culture filtrate. Scand J Immunol (1994) 1.27

Sensitivity to sensitins and tuberculin in Swedish children. I. A study of schoolchildren in an urban area. Tubercle (1991) 1.27

Isolated acute vertigo in the elderly; vestibular or vascular disease? Acta Neurol Scand (1995) 1.25

Mycobacterial sensitins: where are we now? Rev Infect Dis (1982) 1.25

Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation. Hum Gene Ther (1998) 1.25

Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells. J Exp Med (2000) 1.24

Synthetic fibronectin peptides interrupt inflammatory cell infiltration in transforming growth factor beta 1 knockout mice. Proc Natl Acad Sci U S A (1994) 1.23

Improved quantitation of minimal residual disease in multiple myeloma using real-time polymerase chain reaction and plasmid-DNA complementarity determining region III standards. Cancer Res (1998) 1.23

Classification of Mycobacterium simiae by means of comparative reciprocal intradermal sensitin testing on guinea-pigs and deoxyribonucleic acid hybridization. Acta Pathol Microbiol Immunol Scand B (1982) 1.21

Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders. Am J Pathol (1995) 1.19

Morphological changes induced by phospholipase C and by sphingomyelinase on large unilamellar vesicles: a cryo-transmission electron microscopy study of liposome fusion. Biophys J (1997) 1.17

High levels of human glucocerebrosidase activity in macrophages of long-term reconstituted mice after retroviral infection of hematopoietic stem cells. Blood (1992) 1.17

Determination of fatty acids and carbohydrate monomers in micro-organisms by means of glass capillary gas chromatography: analysis of Mycobacterium gordonae and Mycobacterium scrofulaceum. J Gen Microbiol (1983) 1.15

Effect of polyethyleneglycol-phospholipids on aggregate structure in preparations of small unilamellar liposomes. Biophys J (1997) 1.15

Lenticular opacities in individuals exposed to ionizing radiation in infancy. Radiat Res (1999) 1.14

The friction cost method: a comment. J Health Econ (1997) 1.14

An ancient retrovirus-like element contains hot spots for SINE insertion. Genetics (2001) 1.14

Influence of pH and storage time on the sorption and solubility behaviour of three composite resin materials. J Dent (2001) 1.14

Mycolic acid patterns of representatives of Mycobacterium bovis BCG. J Gen Microbiol (1984) 1.14

Trichophyton asthma: sensitisation of bronchi and upper airways to dermatophyte antigen. Lancet (1989) 1.14

The incidence and time-course of latanoprost-induced iridial pigmentation as a function of eye color. Surv Ophthalmol (1997) 1.13

Stable gene transfer and tissue-specific expression of a human globin gene using adenoviral vectors. EMBO J (1986) 1.13

European School of Oncology Advisory report to the Commission of the European Communities for the "Europe Against Cancer Programme" cost-effectiveness in cancer care. Eur J Cancer (1995) 1.12

The blood groups of Icelanders. Ann Hum Genet (1973) 1.12

Transfer of genes into hematopoietic cells using recombinant DNA viruses. Proc Natl Acad Sci U S A (1985) 1.12

Dual skin testing with Mycobacterium avium sensitin and purified protein derivative to discriminate pulmonary disease due to M. avium complex from pulmonary disease due to Mycobacterium tuberculosis. J Infect Dis (1998) 1.11

A randomized trial of intranasal beclomethasone dipropionate after polypectomy. Rhinology (1982) 1.11

Child health services in transition: I. Theories, methods and launching. Acta Paediatr (2005) 1.11

Immunoglobulin G subclass deficiencies. Int Arch Allergy Appl Immunol (1987) 1.10

Survival rate and failure characteristics for two post designs. J Prosthet Dent (1995) 1.10

Corynebacterium equi Magnusson isolated from a tuberculoid lesion in a child with adenitis colli. Dan Med Bull (1968) 1.10

A new sensitive and highly specific chromogenic peptide substrate for factor Xa. Thromb Res (1977) 1.09

The role of Smad signaling in hematopoiesis and translational hematology. Leukemia (2011) 1.08

Dual skin testing with Mycobacterium avium sensitin and purified protein derivative: an open study of patients with M. avium complex infection or tuberculosis. Clin Infect Dis (1994) 1.08

Pharmacological treatment of vertigo. Acta Otolaryngol Suppl (1988) 1.08

Quantitative comparison of the mycolic and fatty acid compositions of Mycobacterium leprae and Mycobacterium gordonae. J Gen Microbiol (1985) 1.07

Child health services in transition: II. Mothers' perceptions of 18-month-old children in the light of socio-economic status and some subjective factors. Acta Paediatr (2005) 1.07

Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene. Mol Pathol (1999) 1.06

Carbon fiber reinforced root canal posts. Mechanical and cytotoxic properties. Eur J Oral Sci (1997) 1.06

Training methods for horses: habituation to a frightening stimulus. Equine Vet J (2006) 1.05

Dissimilarities between the central control of thirst and the release of antidiuretic hormone (ADH). Acta Physiol Scand (1967) 1.05