Published in Hum Mol Genet on November 30, 2010
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (2013) 4.12
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol (2015) 1.53
Live-cell chromosome dynamics and outcome of X chromosome pairing events during ES cell differentiation. Cell (2011) 1.36
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Res (2012) 1.35
Xist regulation and function explored. Hum Genet (2011) 1.28
X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells. Hum Genet (2011) 1.14
The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever. PLoS Genet (2011) 1.08
Dosage compensation in mammals. Cold Spring Harb Perspect Biol (2015) 1.07
MOF-associated complexes ensure stem cell identity and Xist repression. Elife (2014) 1.06
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells. Hum Genet (2011) 1.04
X-chromosome inactivation: molecular mechanisms from the human perspective. Hum Genet (2011) 1.03
Noncoding RNA in oncogenesis: a new era of identifying key players. Int J Mol Sci (2013) 1.03
Reactivation of the inactive X chromosome in development and reprogramming. Cell Mol Life Sci (2012) 0.98
Guided by RNAs: X-inactivation as a model for lncRNA function. J Mol Biol (2013) 0.96
Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. Stem Cells (2012) 0.94
Long noncoding RNA FTX inhibits hepatocellular carcinoma proliferation and metastasis by binding MCM2 and miR-374a. Oncogene (2016) 0.93
Long nonoding RNAs in the X-inactivation center. Chromosome Res (2013) 0.92
Conformation regulation of the X chromosome inactivation center: a model. PLoS Comput Biol (2011) 0.92
Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome. BMC Genomics (2012) 0.91
A prominent and conserved role for YY1 in Xist transcriptional activation. Nat Commun (2014) 0.90
Clustered transcripts that escape X inactivation at mouse XqD. Mamm Genome (2011) 0.90
A statistical framework to predict functional non-coding regions in the human genome through integrated analysis of annotation data. Sci Rep (2015) 0.87
Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation. PLoS Genet (2015) 0.85
Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos. Sci Rep (2014) 0.84
Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders. EBioMedicine (2015) 0.84
Coupling of X-chromosome reactivation with the pluripotent stem cell state. RNA Biol (2014) 0.84
Sex-specific silencing of X-linked genes by Xist RNA. Proc Natl Acad Sci U S A (2016) 0.83
Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding. BMC Genet (2014) 0.82
Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation. PLoS One (2011) 0.82
Identification of an imprinted gene cluster in the X-inactivation center. PLoS One (2013) 0.82
Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development. BMC Genomics (2015) 0.82
Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation. Biochim Biophys Acta (2015) 0.82
X chromosome inactivation in a female carrier of a 1.28 Mb deletion encompassing the human X inactivation centre. Philos Trans R Soc Lond B Biol Sci (2017) 0.81
Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma. Oncotarget (2016) 0.80
What makes the maternal X chromosome resistant to undergoing imprinted X inactivation? Philos Trans R Soc Lond B Biol Sci (2017) 0.80
Nonrandom X chromosome inactivation is influenced by multiple regions on the murine X chromosome. Genetics (2012) 0.80
A Comprehensive Analysis of Cell Type-Specific Nuclear RNA From Neurons and Glia of the Brain. Biol Psychiatry (2016) 0.80
The X chromosome in space. Nat Rev Genet (2017) 0.79
Cis- and trans-regulation in X inactivation. Chromosoma (2015) 0.79
Gene expression profiling of peripheral blood mononuclear cells in the setting of peripheral arterial disease. J Clin Bioinforma (2012) 0.79
Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome. Epigenetics (2015) 0.78
Interplay of chromatin modifications and non-coding RNAs in the heart. Epigenetics (2013) 0.78
The evolutionary pathway of x chromosome inactivation in mammals. Acta Naturae (2013) 0.78
Long non-coding RNAs and human X-chromosome regulation: a coat for the active X chromosome. RNA Biol (2013) 0.77
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression. PLoS Genet (2017) 0.77
Determining the role of skewed X-chromosome inactivation in developing muscle symptoms in carriers of Duchenne muscular dystrophy. Hum Genet (2016) 0.76
Xist and Tsix Transcription Dynamics Is Regulated by the X-to-Autosome Ratio and Semistable Transcriptional States. Mol Cell Biol (2016) 0.76
Regulation of Mammalian Gene Dosage by Long Noncoding RNAs. Biomolecules (2013) 0.76
CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma. Mol Ther (2017) 0.75
Systematic Mapping of RNA-Chromatin Interactions In Vivo. Curr Biol (2017) 0.75
Long noncoding RNA FTX is upregulated in gliomas and promotes proliferation and invasion of glioma cells by negatively regulating miR-342-3p. Lab Invest (2017) 0.75
Unusual semi-extractability as a hallmark of nuclear body-associated architectural noncoding RNAs. EMBO J (2017) 0.75
Sex chromosome abnormalities and psychiatric diseases. Oncotarget (2016) 0.75
Integrating Epigenomics into the Understanding of Biomedical Insight. Bioinform Biol Insights (2016) 0.75
Overexpression of OCT4A ortholog elevates endogenous XIST in porcine parthenogenic blastocysts. J Reprod Dev (2015) 0.75
Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression. Mol Cell Biol (2015) 0.75
Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice. PLoS Genet (2016) 0.75
Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse. PLoS Genet (2016) 0.75
Long non-coding RNAs in hepatocellular carcinoma: Potential roles and clinical implications. World J Gastroenterol (2017) 0.75
Regulatory Roles of Long Non-Coding RNAs in the Central Nervous System and Associated Neurodegenerative Diseases. Front Cell Neurosci (2017) 0.75
Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia. Nature (2006) 5.06
Integr8 and Genome Reviews: integrated views of complete genomes and proteomes. Nucleic Acids Res (2005) 4.15
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell (2010) 3.70
Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation. Nat Cell Biol (2006) 3.66
Tree pattern matching in phylogenetic trees: automatic search for orthologs or paralogs in homologous gene sequence databases. Bioinformatics (2005) 3.62
Recombination drives the evolution of GC-content in the human genome. Mol Biol Evol (2004) 3.50
The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Science (2006) 3.50
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (2005) 2.91
Genome-wide studies highlight indirect links between human replication origins and gene regulation. Proc Natl Acad Sci U S A (2008) 2.77
Molecular coupling of Xist regulation and pluripotency. Science (2008) 2.74
Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature (2005) 2.46
Differential histone H3 Lys-9 and Lys-27 methylation profiles on the X chromosome. Mol Cell Biol (2004) 2.43
A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex. Mol Cell (2010) 2.31
2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol (2010) 2.30
The relationship among gene expression, the evolution of gene dosage, and the rate of protein evolution. PLoS Genet (2010) 2.20
Adaptation or biased gene conversion? Extending the null hypothesis of molecular evolution. Trends Genet (2007) 2.18
Translational control of intron splicing in eukaryotes. Nature (2008) 2.15
Neutral effect of recombination on base composition in Drosophila. Genet Res (2003) 2.11
Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. Genome Res (2002) 2.04
Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations. Nat Commun (2011) 2.03
Databases of homologous gene families for comparative genomics. BMC Bioinformatics (2009) 2.01
The endogenous retroviral locus ERVWE1 is a bona fide gene involved in hominoid placental physiology. Proc Natl Acad Sci U S A (2004) 1.98
Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation. Genes Dev (2005) 1.92
The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes. Genome Res (2013) 1.83
Genome-scale coestimation of species and gene trees. Genome Res (2012) 1.82
Molecular coupling of Tsix regulation and pluripotency. Nature (2010) 1.69
Regulation of the large (approximately 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn. Nucleic Acids Res (2004) 1.67
Preventing dangerous nonsense: selection for robustness to transcriptional error in human genes. PLoS Genet (2011) 1.63
Evolutionary origin and maintenance of coexpressed gene clusters in mammals. Mol Biol Evol (2006) 1.62
GC-biased gene conversion promotes the fixation of deleterious amino acid changes in primates. Trends Genet (2008) 1.54
ROSO: optimizing oligonucleotide probes for microarrays. Bioinformatics (2004) 1.53
Pervasive positive selection on duplicated and nonduplicated vertebrate protein coding genes. Genome Res (2008) 1.45
Ultra-fast sequence clustering from similarity networks with SiLiX. BMC Bioinformatics (2011) 1.40
HOPPSIGEN: a database of human and mouse processed pseudogenes. Nucleic Acids Res (2005) 1.38
The Paramecium germline genome provides a niche for intragenic parasitic DNA: evolutionary dynamics of internal eliminated sequences. PLoS Genet (2012) 1.38
Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues. Proc Natl Acad Sci U S A (2010) 1.37
Relationship between gene expression and GC-content in mammals: statistical significance and biological relevance. Hum Mol Genet (2004) 1.33
No evidence for tissue-specific adaptation of synonymous codon usage in humans. Mol Biol Evol (2005) 1.32
The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene. EMBO J (2004) 1.31
Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program. Genes Dev (2006) 1.29
The decline of isochores in mammals: an assessment of the GC content variation along the mammalian phylogeny. J Mol Evol (2004) 1.28
Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies. Nucleic Acids Res (2007) 1.28
An essential role for the DXPas34 tandem repeat and Tsix transcription in the counting process of X chromosome inactivation. Proc Natl Acad Sci U S A (2006) 1.28
Detecting positive selection within genomes: the problem of biased gene conversion. Philos Trans R Soc Lond B Biol Sci (2010) 1.25
Employment opportunities for non-coding RNAs. FEBS Lett (2004) 1.24
Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation. PLoS Genet (2006) 1.22
Congenic mice: cutting tools for complex immune disorders. Nat Rev Immunol (2003) 1.22
XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells. Nat Genet (2013) 1.20
Evidence that functional transcription units cover at least half of the human genome. Trends Genet (2004) 1.15
Functional role of epsilon-tubulin in the assembly of the centriolar microtubule scaffold. J Cell Biol (2002) 1.14
When X-inactivation meets pluripotency: an intimate rendezvous. FEBS Lett (2009) 1.13
Homology-dependent methylation in primate repetitive DNA. Proc Natl Acad Sci U S A (2005) 1.13
Gene expression in a paleopolyploid: a transcriptome resource for the ciliate Paramecium tetraurelia. BMC Genomics (2010) 1.12
Integrated databanks access and sequence/structure analysis services at the PBIL. Nucleic Acids Res (2003) 1.11
Evidence of selection on the domesticated ERVWE1 env retroviral element involved in placentation. Mol Biol Evol (2004) 1.09
The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever. PLoS Genet (2011) 1.08
Expected relationship between the silent substitution rate and the GC content: implications for the evolution of isochores. J Mol Evol (2002) 1.06
Interactions between conserved domains within homodimers in the BIG1, BIG2, and GBF1 Arf guanine nucleotide exchange factors. J Biol Chem (2007) 1.05
Promoter-restricted H3 Lys 4 di-methylation is an epigenetic mark for monoallelic expression. Hum Mol Genet (2003) 1.05
Placenta-specific INSL4 expression is mediated by a human endogenous retrovirus element. Biol Reprod (2002) 1.03
Polymorphix: a sequence polymorphism database. Nucleic Acids Res (2005) 1.03
Differential retention of metabolic genes following whole-genome duplication. Mol Biol Evol (2009) 1.02
Evidence for widespread GC-biased gene conversion in eukaryotes. Genome Biol Evol (2012) 1.00
The relationship between DNA replication and human genome organization. Mol Biol Evol (2009) 1.00
Identitag, a relational database for SAGE tag identification and interspecies comparison of SAGE libraries. BMC Bioinformatics (2004) 0.99
Is RAD-seq suitable for phylogenetic inference? An in silico assessment and optimization. Ecol Evol (2013) 0.99
Tagging genes with cassette-exchange sites. Nucleic Acids Res (2005) 0.98
Energy biogenesis: one key for coordinating two genomes. Trends Genet (2005) 0.97
GC-biased gene conversion in yeast is specifically associated with crossovers: molecular mechanisms and evolutionary significance. Mol Biol Evol (2013) 0.95
Unexpected observations after mapping LongSAGE tags to the human genome. BMC Bioinformatics (2007) 0.95
Origin and evolution of the long non-coding genes in the X-inactivation center. Biochimie (2011) 0.93
GC content evolution of the human and mouse genomes: insights from the study of processed pseudogenes in regions of different recombination rates. J Mol Evol (2006) 0.93
The GC content of primates and rodents genomes is not at equilibrium: a reply to Antezana. J Mol Evol (2006) 0.93
X-inactivation modifies disease severity in female carriers of murine X-linked Alport syndrome. Nephrol Dial Transplant (2009) 0.92
Patterns of selection against transposons inferred from the distribution of Tc1, Tc3 and Tc5 insertions in the mut-7 line of the nematode Caenorhabditis elegans. Genetics (2003) 0.92
The role of antisense transcription in the regulation of X-inactivation. Curr Top Dev Biol (2004) 0.92
An embryonic story: analysis of the gene regulative network controlling Xist expression in mouse embryonic stem cells. Bioessays (2010) 0.92
The coupling of X-chromosome inactivation to pluripotency. Annu Rev Cell Dev Biol (2011) 0.91
Meiotic recombination favors the spreading of deleterious mutations in human populations. Hum Mutat (2011) 0.91
Controlling X-inactivation in mammals: what does the centre hold? Semin Cell Dev Biol (2003) 0.90
Nap1l2 promotes histone acetylation activity during neuronal differentiation. Mol Cell Biol (2007) 0.90
Monoallelic expression and tissue specificity are associated with high crossover rates. Trends Genet (2009) 0.89
ISG20L2, a novel vertebrate nucleolar exoribonuclease involved in ribosome biogenesis. Mol Cell Proteomics (2007) 0.89
Random X-chromosome inactivation: skewing lessons for mice and men. Curr Opin Genet Dev (2006) 0.88
Natural history of the ERVWE1 endogenous retroviral locus. Retrovirology (2005) 0.88
Silencing specific Paramecium tetraurelia genes by feeding double-stranded RNA. Cold Spring Harb Protoc (2010) 0.87
Subcellular localization of 14-3-3 proteins in Toxoplasma gondii tachyzoites and evidence for a lipid raft-associated form. FEMS Microbiol Lett (2003) 0.87
Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 diabetes locus Idd6. Hum Mol Genet (2006) 0.87
A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes. Genome Biol (2010) 0.86
Genetics and epigenetics of the X chromosome. Ann N Y Acad Sci (2010) 0.86
Paramecium tetraurelia: the renaissance of an early unicellular model. Cold Spring Harb Protoc (2010) 0.86