PubRank

Michael R Sawaya

Author PubWeight™ 146.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure of the cross-beta spine of amyloid-like fibrils. Nature 2005 11.56
2 Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 2006 7.29
3 Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell 2012 6.83
4 Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science 2009 3.78
5 Protein structures forming the shell of primitive bacterial organelles. Science 2005 3.20
6 Atomic view of a toxic amyloid small oligomer. Science 2012 3.13
7 Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature 2005 2.99
8 An architectural framework that may lie at the core of the postsynaptic density. Science 2006 2.91
9 Structure and mechanisms of a protein-based organelle in Escherichia coli. Science 2010 2.45
10 Atomic-level models of the bacterial carboxysome shell. Science 2008 2.36
11 Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science 2012 2.33
12 Dimerization allows DNA target site recognition by the NarL response regulator. Nat Struct Biol 2002 2.05
13 The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell 2003 1.99
14 Crystal structure of human fibrinogen. Biochemistry 2009 1.97
15 Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci 2010 1.95
16 Molecular mechanisms for protein-encoded inheritance. Nat Struct Mol Biol 2009 1.94
17 Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin). Protein Sci 2008 1.89
18 Deposition diseases and 3D domain swapping. Structure 2006 1.88
19 Expanding metabolism for biosynthesis of nonnatural alcohols. Proc Natl Acad Sci U S A 2008 1.86
20 An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril. Proc Natl Acad Sci U S A 2004 1.85
21 Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A 2011 1.76
22 Discovery and characterization of a unique mycobacterial heme acquisition system. Proc Natl Acad Sci U S A 2011 1.71
23 Bacterial inclusion bodies contain amyloid-like structure. PLoS Biol 2008 1.63
24 Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell 2004 1.59
25 Towards a pharmacophore for amyloid. PLoS Biol 2011 1.58
26 Structural analysis of CsoS1A and the protein shell of the Halothiobacillus neapolitanus carboxysome. PLoS Biol 2007 1.57
27 The crystal structure of a cyanobacterial water-soluble carotenoid binding protein. Structure 2003 1.54
28 Structure and folding of a designed knotted protein. Proc Natl Acad Sci U S A 2010 1.48
29 The structural biology of protein aggregation diseases: Fundamental questions and some answers. Acc Chem Res 2006 1.47
30 Molecular basis for insulin fibril assembly. Proc Natl Acad Sci U S A 2009 1.47
31 Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process. Protein Sci 2009 1.46
32 Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J Mol Biol 2004 1.43
33 The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif. J Biol Chem 2006 1.42
34 Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates. Proc Natl Acad Sci U S A 2012 1.39
35 Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proc Natl Acad Sci U S A 2011 1.33
36 Granulysin crystal structure and a structure-derived lytic mechanism. J Mol Biol 2003 1.30
37 Regulation of enzyme localization by polymerization: polymer formation by the SAM domain of diacylglycerol kinase delta1. Structure 2008 1.28
38 Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics. J Am Chem Soc 2011 1.27
39 Insights from multiple structures of the shell proteins from the beta-carboxysome. Protein Sci 2009 1.27
40 Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J Biol Chem 2005 1.26
41 Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc Natl Acad Sci U S A 2008 1.25
42 Structural insight into the mechanisms of transport across the Salmonella enterica Pdu microcompartment shell. J Biol Chem 2010 1.24
43 Structure of the PduU shell protein from the Pdu microcompartment of Salmonella. Structure 2008 1.24
44 β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat Struct Mol Biol 2010 1.22
45 The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin. Proc Natl Acad Sci U S A 2005 1.18
46 Two amyloid States of the prion protein display significantly different folding patterns. J Mol Biol 2010 1.16
47 Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure 2005 1.16
48 Structure of the dimerization domain of DiGeorge critical region 8. Protein Sci 2010 1.16
49 Crystal structure of a RuBisCO-like protein from the green sulfur bacterium Chlorobium tepidum. Structure 2005 1.14
50 Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD. Biochemistry 2002 1.13
51 The light reactions: a guide to recent acquisitions for the picture gallery. Plant Cell 2005 1.12
52 The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity. Proc Natl Acad Sci U S A 2014 1.11
53 Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide. J Am Chem Soc 2011 1.10
54 Analysis of lattice-translocation disorder in the layered hexagonal structure of carboxysome shell protein CsoS1C. Acta Crystallogr D Biol Crystallogr 2009 1.09
55 The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Sci 2012 1.05
56 Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J Biol Chem 2010 1.01
57 Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning. Acta Crystallogr D Biol Crystallogr 2003 0.99
58 An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci 2011 0.98
59 Multiple forms of Spire-actin complexes and their functional consequences. J Biol Chem 2012 0.98
60 The crystal structure of the first enzyme in the pantothenate biosynthetic pathway, ketopantoate hydroxymethyltransferase, from M tuberculosis. Structure 2003 0.97
61 Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J Mol Biol 2005 0.96
62 Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophys Chem 2003 0.95
63 Atomic structures suggest determinants of transmission barriers in mammalian prion disease. Biochemistry 2011 0.93
64 Multidimensional structure-activity relationship of a protein in its aggregated states. Angew Chem Int Ed Engl 2010 0.93
65 Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. J Am Chem Soc 2013 0.93
66 An introduction to biomolecular graphics. PLoS Comput Biol 2010 0.93
67 Directed evolution and structural characterization of a simvastatin synthase. Chem Biol 2009 0.92
68 Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proc Natl Acad Sci U S A 2013 0.92
69 The Tim8-Tim13 complex has multiple substrate binding sites and binds cooperatively to Tim23. J Mol Biol 2008 0.90
70 The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase. Acta Crystallogr D Biol Crystallogr 2005 0.90
71 Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J Am Chem Soc 2013 0.90
72 Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr D Biol Crystallogr 2002 0.90
73 Structure of the RuBisCO chaperone RbcX from Synechocystis sp. PCC6803. Acta Crystallogr D Biol Crystallogr 2007 0.89
74 Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Sci 2002 0.87
75 Structural states and dynamics of the D-loop in actin. Biophys J 2012 0.87
76 Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus. Plant Cell Physiol 2003 0.87
77 Structures and functional implications of an AMP-binding cystathionine beta-synthase domain protein from a hyperthermophilic archaeon. J Mol Biol 2008 0.87
78 Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation. Protein Sci 2011 0.86
79 Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole. J Biol Chem 2014 0.85
80 Crystal structure of an RNA.DNA hybrid reveals intermolecular intercalation: dimer formation by base-pair swapping. Proc Natl Acad Sci U S A 2003 0.85
81 X-ray crystallographic structure of an artificial beta-sheet dimer. J Am Chem Soc 2010 0.85
82 Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima. Protein Sci 2011 0.84
83 Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci 2010 0.84
84 Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chem Commun (Camb) 2010 0.83
85 Structural and biochemical characterization of the salicylyl-acyltranferase SsfX3 from a tetracycline biosynthetic pathway. J Biol Chem 2011 0.83
86 Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. PLoS One 2013 0.82
87 Crystal structure of the central coiled-coil domain from human liprin-β2. Biochemistry 2011 0.81
88 Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci 2014 0.81
89 Structure-based design of functional amyloid materials. J Am Chem Soc 2014 0.80
90 Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J Phys Chem B 2014 0.80
91 Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation. Protein Sci 2011 0.80
92 Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A 2010 0.80
93 Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Sci 2009 0.80
94 Crystal structure of human L-isoaspartyl methyltransferase. J Biol Chem 2002 0.78
95 (Quasi-)racemic X-ray structures of glycosylated and non-glycosylated forms of the chemokine Ser-CCL1 prepared by total chemical synthesis. Angew Chem Int Ed Engl 2014 0.77
96 Apo and ligand-bound structures of ModA from the archaeon Methanosarcina acetivorans. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.77
97 The role of Cys-298 in aldose reductase function. J Biol Chem 2010 0.77
98 Function of AGCA tetrads in (CAG)n repeats. Nucleic Acids Symp Ser (Oxf) 2004 0.75
99 Structure of cytochrome c6 from Arthrospira maxima: an assembly of 24 subunits in a nearly symmetric shell. Acta Crystallogr D Biol Crystallogr 2002 0.75
100 Applications of bioinformatics to protein structures: how protein structure and bioinformatics overlap. Methods Mol Biol 2009 0.75
101 Ultrafast Time-Resolved Studies on Fluorescein for Recognition Strands Architecture in Amyloid Fibrils. J Phys Chem B 2017 0.75