Published in Proc Natl Acad Sci U S A on December 08, 2010
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis. Cell (2012) 2.18
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa. Proc Natl Acad Sci U S A (2011) 1.87
Stages of ciliogenesis and regulation of ciliary length. Differentiation (2011) 1.59
Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins. Cilia (2012) 1.27
Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation. Proc Natl Acad Sci U S A (2012) 1.20
Exome sequencing and cis-regulatory mapping identify mutations in MAK, a gene encoding a regulator of ciliary length, as a cause of retinitis pigmentosa. Am J Hum Genet (2011) 1.16
Diversity, classification and function of the plant protein kinase superfamily. Philos Trans R Soc Lond B Biol Sci (2012) 1.08
Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina. PLoS One (2011) 1.01
The role of primary cilia in the development and disease of the retina. Organogenesis (2013) 0.98
Autosomal recessive retinitis pigmentosa caused by mutations in the MAK gene. Invest Ophthalmol Vis Sci (2011) 0.98
CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner. EMBO Rep (2013) 0.98
Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling. Proc Natl Acad Sci U S A (2014) 0.92
Primary cilia and kidney injury: current research status and future perspectives. Am J Physiol Renal Physiol (2013) 0.90
Ultrastructural visualization of trans-ciliary rhodopsin cargoes in mammalian rods. Cilia (2015) 0.90
Basolateral Mg2+ extrusion via CNNM4 mediates transcellular Mg2+ transport across epithelia: a mouse model. PLoS Genet (2013) 0.89
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport. EMBO J (2014) 0.89
Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length. Proc Natl Acad Sci U S A (2013) 0.88
Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells. PLoS One (2014) 0.85
A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration. Am J Pathol (2014) 0.82
Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity. PLoS One (2013) 0.82
Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908. J Biol Chem (2012) 0.81
Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice. Cytoskeleton (Hoboken) (2015) 0.78
Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome. PLoS One (2013) 0.77
Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice. PLoS One (2015) 0.77
A NIMA-related kinase, CNK4, regulates ciliary stability and length. Mol Biol Cell (2016) 0.76
No evidence for a genetic blueprint: The case of the "complex" mammalian photoreceptor. Indian J Ophthalmol (2015) 0.75
Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport. J Biol Chem (2016) 0.75
Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. PLoS Genet (2016) 0.75
Intraflagellar transport. Nat Rev Mol Cell Biol (2002) 10.86
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell (2007) 10.75
When cilia go bad: cilia defects and ciliopathies. Nat Rev Mol Cell Biol (2007) 8.28
HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell (2007) 6.50
Centrioles, centrosomes, and cilia in health and disease. Cell (2009) 5.82
The vertebrate primary cilium in development, homeostasis, and disease. Cell (2009) 5.29
The fine structure of the retina studied with the electron microscope. IV. Morphogenesis of outer segments of retinal rods. J Biophys Biochem Cytol (1959) 4.99
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet (2005) 4.76
Genomic analysis of mouse retinal development. PLoS Biol (2004) 4.66
Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors. Cell (2000) 4.51
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J Cell Biol (2002) 3.85
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. J Neurosci (2007) 3.79
A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. Cell (1998) 3.09
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat Neurosci (2003) 3.08
Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. Proc Natl Acad Sci U S A (2004) 3.01
Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau. J Cell Sci (1992) 2.42
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation. Nat Neurosci (2008) 2.35
A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3). Proc Natl Acad Sci U S A (2000) 2.19
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat Cell Biol (2008) 2.03
RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia. Invest Ophthalmol Vis Sci (2003) 2.00
The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A (2003) 1.96
A novel MAP kinase regulates flagellar length in Chlamydomonas. Curr Biol (2003) 1.84
Mutations in a gene encoding a new oxygen-regulated photoreceptor protein cause dominant retinitis pigmentosa. Nat Genet (1999) 1.81
The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment development. Dev Biol (2008) 1.76
Cloning of the cDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies. Neuron (1992) 1.76
Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons. Neuron (2004) 1.75
Kinetics of rod outer segment renewal in the developing mouse retina. J Cell Biol (1973) 1.75
Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors. Dev Dyn (2008) 1.73
Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration. Neuron (2004) 1.70
The retinitis pigmentosa 1 protein is a photoreceptor microtubule-associated protein. J Neurosci (2004) 1.68
Intraflagellar transport molecules in ciliary and nonciliary cells of the retina. J Cell Biol (2010) 1.50
A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis. Mol Cell Biol (1990) 1.46
RP1 is required for the correct stacking of outer segment discs. Invest Ophthalmol Vis Sci (2003) 1.42
LmxMPK9, a mitogen-activated protein kinase homologue affects flagellar length in Leishmania mexicana. Mol Microbiol (2005) 1.35
Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans. Proc Natl Acad Sci U S A (2007) 1.31
A testicular germ cell-associated serine-threonine kinase, MAK, is dispensable for sperm formation. Mol Cell Biol (2002) 1.24
The sensory cilium of retinal rods is analogous to the transitional zone of motile cilia. Cell Tissue Res (1975) 1.12
Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. J Biol Chem (2002) 1.02
Characterization and expression analysis of the murine rck gene: a protein kinase with a potential function in sensory cells. Differentiation (1993) 0.98
Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci (2009) 0.97
Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. Brain (2007) 4.82
Guidelines for basic multifocal electroretinography (mfERG). Doc Ophthalmol (2003) 4.53
ISCEV standard for clinical multifocal electroretinography (mfERG) (2011 edition). Doc Ophthalmol (2011) 3.19
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat Neurosci (2003) 3.08
ISCEV guidelines for clinical multifocal electroretinography (2007 edition). Doc Ophthalmol (2007) 2.50
Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation. Nat Neurosci (2008) 2.35
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A (2009) 2.20
Dissociated optic nerve fiber layer appearance after internal limiting membrane peeling for idiopathic macular holes. Ophthalmology (2005) 2.12
Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development (2006) 2.09
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat Cell Biol (2008) 2.03
Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity (2003) 2.03
Cord blood transplantation combined with rituximab for Wiskott-Aldrich syndrome with autoimmune thrombotic thrombocytopenic purpura. J Allergy Clin Immunol (2013) 2.00
On experiences of i2b2 (Informatics for integrating biology and the bedside) database with Japanese clinical patients' data. Bioinformation (2011) 1.82
Endoplasmic reticulum stress induces autophagy in renal proximal tubular cells. Nephrol Dial Transplant (2009) 1.76
Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle. Nucleic Acids Res (2005) 1.60
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. Nat Neurosci (2011) 1.57
Severe intraocular inflammation after intravitreal injection of bevacizumab. Ophthalmology (2010) 1.49
Subretinal transplantation of bone marrow mesenchymal stem cells delays retinal degeneration in the RCS rat model of retinal degeneration. Exp Eye Res (2007) 1.48
Functional roles of Otx2 transcription factor in postnatal mouse retinal development. Mol Cell Biol (2007) 1.46
MRI findings from a case of fulminating adult-onset measles encephalitis. Intern Med (2006) 1.40
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
TRPM1 mutations are associated with the complete form of congenital stationary night blindness. Mol Vis (2010) 1.37
Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Mol Ther (2009) 1.37
The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells. J Neurosci (2002) 1.36
A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites. J Neurosci (2011) 1.24
Luminance dependence of neural components that underlies the primate photopic electroretinogram. Invest Ophthalmol Vis Sci (2004) 1.22
A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers. Invest Ophthalmol Vis Sci (2004) 1.20
Function and morphology of macula before and after removal of idiopathic epiretinal membrane. Invest Ophthalmol Vis Sci (2003) 1.19
Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol (2007) 1.19
Primate Retinal Signaling Pathways: Suppressing ON-Pathway Activity in Monkey With Glutamate Analogues Mimics Human CSNB1-NYX Genetic Night Blindness. J Neurophysiol (2004) 1.18
Two novel mutations in the EYS gene are possible major causes of autosomal recessive retinitis pigmentosa in the Japanese population. PLoS One (2012) 1.17
Recording focal macular photopic negative response (PhNR) from monkeys. Invest Ophthalmol Vis Sci (2008) 1.16
TRPM1: a vertebrate TRP channel responsible for retinal ON bipolar function. Cell Calcium (2010) 1.13
Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene. Proc Natl Acad Sci U S A (2013) 1.13
Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina. J Neurosci (2005) 1.12
Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction. PLoS One (2011) 1.12
Changes in focal macular electroretinograms and foveal thickness after vitrectomy for diabetic macular edema. Invest Ophthalmol Vis Sci (2003) 1.12
Generation of a transgenic rabbit model of retinal degeneration. Invest Ophthalmol Vis Sci (2008) 1.11
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Mol Ther (2011) 1.09
Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells. Genesis (2007) 1.08
Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J Neurosci (2010) 1.08
Is Broca's area involved in the processing of passive sentences? An event-related fMRI study. Neuropsychologia (2006) 1.07
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization. Invest Ophthalmol Vis Sci (2008) 1.06
A method for observing silver-stained osteocytes in situ in 3-microm sections using ultra-high voltage electron microscopy tomography. Microsc Microanal (2009) 1.06
Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice. BMC Neurosci (2005) 1.06
Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation. J Neurophysiol (2012) 1.05
Right frontopolar cortex activity correlates with reliability of retrospective rating of confidence in short-term recognition memory performance. Neurosci Res (2010) 1.05
An essential role for RAX homeoprotein and NOTCH-HES signaling in Otx2 expression in embryonic retinal photoreceptor cell fate determination. J Neurosci (2011) 1.05
Reduction of oscillatory potentials and photopic negative response in patients with autosomal dominant optic atrophy with OPA1 mutations. Invest Ophthalmol Vis Sci (2007) 1.05
Foveal thickness in occult macular dystrophy. Am J Ophthalmol (2003) 1.05
Cortical activation in the processing of passive sentences in L1 and L2: an fMRI study. Neuroimage (2005) 1.04
Ultrastructural evidence for thermal injury to pilosebaceous units during the treatment of acne using photopneumatic (PPX) therapy. J Cosmet Laser Ther (2008) 1.03
Selective amplitude reduction of the PhNR after macular hole surgery: ganglion cell damage related to ICG-assisted ILM peeling and gas tamponade. Invest Ophthalmol Vis Sci (2006) 1.03
Anti-cachectic effect of ghrelin in nude mice bearing human melanoma cells. Biochem Biophys Res Commun (2003) 1.02
Corneal endothelial cell damage by free radicals associated with ultrasound oscillation. Arch Ophthalmol (2008) 1.01
Optical coherence tomography and focal macular electroretinogram in eyes with epiretinal membrane and macular pseudohole. Am J Ophthalmol (2003) 1.01
Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina. PLoS One (2011) 1.01
Correlation between macular volume and focal macular electroretinogram in patients with retinitis pigmentosa. Invest Ophthalmol Vis Sci (2008) 1.00
Effects of flanking genes on the phenotypes of mice deficient in basigin/CD147. Biochem Biophys Res Commun (2004) 1.00
mGluR6 deletion renders the TRPM1 channel in retina inactive. J Neurophysiol (2011) 1.00
Effect of Pupil Size on Flicker ERGs Recorded With RETeval System: New Mydriasis-Free Full-Field ERG System. Invest Ophthalmol Vis Sci (2015) 0.99
CSF chemokine levels in relapsing neuromyelitis optica and multiple sclerosis. J Neuroimmunol (2004) 0.99
Focal macular electroretinograms before and after removal of choroidal neovascular lesions. Invest Ophthalmol Vis Sci (2002) 0.98
Multiple brain networks for visual self-recognition with different sensitivity for motion and body part. Neuroimage (2006) 0.98
Ultrastructural changes during in situ early postmortem autolysis in kidney, pancreas, liver, heart and skeletal muscle of rats. Leg Med (Tokyo) (2004) 0.98
Relationship between retinal layer thickness and focal macular electroretinogram components after epiretinal membrane surgery. Invest Ophthalmol Vis Sci (2013) 0.97
Cortical mechanisms involved in the processing of verbs: an fMRI study. J Cogn Neurosci (2006) 0.97
Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. Ann Bot (2006) 0.97
SMOC1 is essential for ocular and limb development in humans and mice. Am J Hum Genet (2010) 0.97
Isolation and developmental expression of tyrosinase family genes in Xenopus laevis. Pigment Cell Res (2003) 0.97
Cloning and regulation of the vertebrate homologue of lin-41 that functions as a heterochronic gene in Caenorhabditis elegans. Dev Dyn (2006) 0.96
Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Invest Ophthalmol Vis Sci (2011) 0.96