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1
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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model.
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Science
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2007
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8.56
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2
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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.
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Nat Neurosci
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2008
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2.09
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3
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Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
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J Neurosci
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2009
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1.54
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4
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Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.
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J Mol Biol
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2004
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1.42
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5
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Collagen VI protects neurons against Abeta toxicity.
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Nat Neurosci
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2009
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1.19
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6
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Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration.
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J Biol Chem
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2005
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1.13
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7
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Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation.
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J Biol Chem
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2011
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0.95
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8
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Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory.
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J Neurosci
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2013
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0.93
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9
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Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model.
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Food Chem
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2012
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0.87
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10
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Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies.
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PLoS One
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2012
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0.85
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11
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Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees.
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J Agric Food Chem
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2009
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0.84
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12
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ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
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PLoS One
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2010
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0.84
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13
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Two mcm3 mutations affect different steps in the initiation of DNA replication.
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J Biol Chem
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2002
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0.81
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14
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Potential blood biomarker for disease severity in the Taiwanese population with Alzheimer's disease.
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Am J Alzheimers Dis Other Demen
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2012
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0.78
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15
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Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.
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J Neurochem
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2014
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0.75
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