Published in J Mol Biol on July 02, 2004
Cell cycle regulation of DNA replication. Annu Rev Genet (2007) 3.80
Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. Cell (2011) 2.40
Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci U S A (2009) 1.88
Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev (2010) 1.71
Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast. Mol Cell Biol (2006) 1.45
Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication. Mol Biol Cell (2007) 1.44
Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation. EMBO J (2012) 1.37
Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice. Plant Physiol (2007) 1.32
Helicase activation and establishment of replication forks at chromosomal origins of replication. Cold Spring Harb Perspect Biol (2013) 1.32
Biological context networks: a mosaic view of the interactome. Mol Syst Biol (2006) 1.24
Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae. PLoS Genet (2006) 1.22
Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. J Biol Chem (2011) 1.21
The effect of the intra-S-phase checkpoint on origins of replication in human cells. Genes Dev (2011) 1.21
Enigmatic roles of Mcm10 in DNA replication. Trends Biochem Sci (2013) 1.17
Ancient diversification of eukaryotic MCM DNA replication proteins. BMC Evol Biol (2009) 1.17
Nuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast. BMC Mol Biol (2005) 1.15
Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components. EMBO J (2012) 1.15
Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells. Cell Cycle (2009) 1.11
Hexameric ring structure of human MCM10 DNA replication factor. EMBO Rep (2007) 1.10
Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin. Mol Cell Biol (2005) 1.06
Multiple functions for Drosophila Mcm10 suggested through analysis of two Mcm10 mutant alleles. Genetics (2010) 1.02
Alternative mechanisms for coordinating polymerase alpha and MCM helicase. Mol Cell Biol (2009) 1.02
Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae. Genetics (2005) 1.01
Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe. Genetics (2007) 0.98
Mcm10 mediates the interaction between DNA replication and silencing machineries. Genetics (2008) 0.95
Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae. J Biol Chem (2009) 0.94
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. Cell Cycle (2016) 0.92
Mcm10 coordinates the timely assembly and activation of the replication fork helicase. Nucleic Acids Res (2015) 0.88
Ubc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication. Mol Biol Cell (2010) 0.88
MCM10: one tool for all-Integrity, maintenance and damage control. Semin Cell Dev Biol (2014) 0.87
Structural biology of replication initiation factor Mcm10. Subcell Biochem (2012) 0.86
Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation. Nucleic Acids Res (2013) 0.82
Retracted The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase. J Biol Chem (2015) 0.82
Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair. Cell Cycle (2014) 0.82
Emerging players in the initiation of eukaryotic DNA replication. Cell Div (2012) 0.78
An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation. J Mol Biol (2016) 0.78
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the central zinc-binding domain of the human Mcm10 DNA-replication factor. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.75
Insights into the Initiation of Eukaryotic DNA Replication. Nucleus (2015) 0.75
Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks. Genes (Basel) (2017) 0.75
The Mcm2-7- interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing. J Biol Chem (2017) 0.75
An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7. Nucleic Acids Res (2017) 0.75
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (2007) 8.56
A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat Genet (2006) 3.35
Telomere-end processing the terminal nucleotides of human chromosomes. Mol Cell (2005) 2.39
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci (2008) 2.09
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion. EMBO J (2012) 1.65
Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. Mol Biol Cell (2003) 1.60
Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice. J Neurosci (2009) 1.54
Telomere dynamics in macaques and humans. J Gerontol A Biol Sci Med Sci (2007) 1.46
The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings. EMBO Rep (2002) 1.34
Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity. EMBO J (2013) 1.25
Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae. PLoS Genet (2006) 1.22
Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in. Cell Res (2012) 1.20
Collagen VI protects neurons against Abeta toxicity. Nat Neurosci (2009) 1.19
Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration. J Biol Chem (2005) 1.13
Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection. EMBO J (2010) 1.11
Evidence for a role of MCM (mini-chromosome maintenance)5 in transcriptional repression of sub-telomeric and Ty-proximal genes in Saccharomyces cerevisiae. J Biol Chem (2003) 1.09
Mcm7, a subunit of the presumptive MCM helicase, modulates its own expression in conjunction with Mcm1. J Biol Chem (2003) 1.07
Mcm1 binds replication origins. J Biol Chem (2002) 1.05
Alternative mechanisms for coordinating polymerase alpha and MCM helicase. Mol Cell Biol (2009) 1.02
Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae. Genetics (2005) 1.01
Mcm1 promotes replication initiation by binding specific elements at replication origins. Mol Cell Biol (2004) 0.99
Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells (2003) 0.98
Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS Biol (2009) 0.97
Mcm10 mediates the interaction between DNA replication and silencing machineries. Genetics (2008) 0.95
Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation. J Biol Chem (2011) 0.95
Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory. J Neurosci (2013) 0.93
Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance. J Biol Chem (2008) 0.93
Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model. Food Chem (2012) 0.87
Mcm3 is polyubiquitinated during mitosis before establishment of the pre-replication complex. J Biol Chem (2002) 0.86
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading. Nucleic Acids Res (2011) 0.86
Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies. PLoS One (2012) 0.85
Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast. BMC Bioinformatics (2008) 0.85
ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin. PLoS One (2010) 0.84
Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees. J Agric Food Chem (2009) 0.84
Telomere replication: poised but puzzling. J Cell Mol Med (2011) 0.82
Two mcm3 mutations affect different steps in the initiation of DNA replication. J Biol Chem (2002) 0.81
DNA2, a new player in telomere maintenance and tumor suppression. Cell Cycle (2013) 0.79
Ploidy dictates repair pathway choice under DNA replication stress. Genetics (2011) 0.79
Causal link between microsatellite instability and hMRE11 dysfunction in human cancers. Mol Cancer Res (2011) 0.79
Potential blood biomarker for disease severity in the Taiwanese population with Alzheimer's disease. Am J Alzheimers Dis Other Demen (2012) 0.78
CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase. Cell Cycle (2012) 0.77
Mapping the FEN1 interaction domain with hTERT. Biochem Biophys Res Commun (2011) 0.75
Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production. J Neurochem (2014) 0.75